-
1
-
-
34247604351
-
Inflammatory process in type 2 diabetes: the role of cytokines
-
Alexandraki K, Piperi C, Kalofoutis C, Singh J, Alaveras A, Kalofoutis A (2006) Inflammatory process in type 2 diabetes: the role of cytokines. Ann. N. Y. Acad. Sci. 1084, 89-117.
-
(2006)
Ann. N. Y. Acad. Sci.
, vol.1084
, pp. 89-117
-
-
Alexandraki, K.1
Piperi, C.2
Kalofoutis, C.3
Singh, J.4
Alaveras, A.5
Kalofoutis, A.6
-
2
-
-
33846902022
-
Lack of myostatin results in excessive muscle growth but impaired force generation
-
Amthor H, Macharia R, Navarrete R, Schuelke M, Brown SC, Otto A, Voit T, Muntoni F, Vrbova G, Partridge T, Zammit P, Bunger L, Patel K (2007) Lack of myostatin results in excessive muscle growth but impaired force generation. Proc. Natl Acad. Sci. USA 104, 1835-1840.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 1835-1840
-
-
Amthor, H.1
Macharia, R.2
Navarrete, R.3
Schuelke, M.4
Brown, S.C.5
Otto, A.6
Voit, T.7
Muntoni, F.8
Vrbova, G.9
Partridge, T.10
Zammit, P.11
Bunger, L.12
Patel, K.13
-
3
-
-
0030972278
-
Wasting as independent risk factor for mortality in chronic heart failure
-
Anker SD, Ponikowski P, Varney S, Chua TP, Clark AL, Webb-Peploe KM, Harrington D, Kox WJ, Poole-Wilson PA, Coats AJ (1997) Wasting as independent risk factor for mortality in chronic heart failure. Lancet 349, 1050-1053.
-
(1997)
Lancet
, vol.349
, pp. 1050-1053
-
-
Anker, S.D.1
Ponikowski, P.2
Varney, S.3
Chua, T.P.4
Clark, A.L.5
Webb-Peploe, K.M.6
Harrington, D.7
Kox, W.J.8
Poole-Wilson, P.A.9
Coats, A.J.10
-
4
-
-
84876946818
-
A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise
-
Aoi W, Naito Y, Takagi T, Tanimura Y, Takanami Y, Kawai Y, Sakuma K, Hang LP, Mizushima K, Hirai Y, Koyama R, Wada S, Higashi A, Kokura S, Ichikawa H, Yoshikawa T (2013) A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise. Gut 62, 882-889.
-
(2013)
Gut
, vol.62
, pp. 882-889
-
-
Aoi, W.1
Naito, Y.2
Takagi, T.3
Tanimura, Y.4
Takanami, Y.5
Kawai, Y.6
Sakuma, K.7
Hang, L.P.8
Mizushima, K.9
Hirai, Y.10
Koyama, R.11
Wada, S.12
Higashi, A.13
Kokura, S.14
Ichikawa, H.15
Yoshikawa, T.16
-
5
-
-
39749140405
-
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha
-
Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM (2008) HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature 451, 1008-1012.
-
(2008)
Nature
, vol.451
, pp. 1008-1012
-
-
Arany, Z.1
Foo, S.Y.2
Ma, Y.3
Ruas, J.L.4
Bommi-Reddy, A.5
Girnun, G.6
Cooper, M.7
Laznik, D.8
Chinsomboon, J.9
Rangwala, S.M.10
Baek, K.H.11
Rosenzweig, A.12
Spiegelman, B.M.13
-
6
-
-
78651086513
-
PGC-1alpha and myokines in the aging muscle - a mini-review
-
Arnold AS, Egger A, Handschin C (2010) PGC-1alpha and myokines in the aging muscle - a mini-review. Gerontology 57, 37-43.
-
(2010)
Gerontology
, vol.57
, pp. 37-43
-
-
Arnold, A.S.1
Egger, A.2
Handschin, C.3
-
7
-
-
0026720759
-
Physical activity and fitness
-
Astrand PO (1992) Physical activity and fitness. Am. J. Clin. Nutr. 55, 1231S-1236S.
-
(1992)
Am. J. Clin. Nutr.
, vol.55
-
-
Astrand, P.O.1
-
8
-
-
0028049995
-
Penetration of interleukin-6 across the murine blood-brain barrier
-
Banks WA, Kastin AJ, Gutierrez EG (1994) Penetration of interleukin-6 across the murine blood-brain barrier. Neurosci Lett. 179, 53-56.
-
(1994)
Neurosci Lett.
, vol.179
, pp. 53-56
-
-
Banks, W.A.1
Kastin, A.J.2
Gutierrez, E.G.3
-
9
-
-
84855351190
-
Interleukin-15 treatment improves glucose homeostasis and insulin sensitivity in obese mice
-
Barra NG, Chew MV, Holloway AC, Ashkar AA (2012) Interleukin-15 treatment improves glucose homeostasis and insulin sensitivity in obese mice. Diabetes Obes. Metab. 14, 190-193.
-
(2012)
Diabetes Obes. Metab.
, vol.14
, pp. 190-193
-
-
Barra, N.G.1
Chew, M.V.2
Holloway, A.C.3
Ashkar, A.A.4
-
10
-
-
0037358776
-
Myostatin expression in age and denervation-induced skeletal muscle atrophy
-
Baumann AP, Ibebunjo C, Grasser WA, Paralkar VM (2003) Myostatin expression in age and denervation-induced skeletal muscle atrophy. J. Musculoskelet. Neuronal Interact. 3, 8-16.
-
(2003)
J. Musculoskelet. Neuronal Interact.
, vol.3
, pp. 8-16
-
-
Baumann, A.P.1
Ibebunjo, C.2
Grasser, W.A.3
Paralkar, V.M.4
-
11
-
-
79958241817
-
Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology
-
Belarbi K, Burnouf S, Fernandez-Gomez FJ, Laurent C, Lestavel S, Figeac M, Sultan A, Troquier L, Leboucher A, Caillierez R, Grosjean ME, Demeyer D, Obriot H, Brion I, Barbot B, Galas MC, Staels B, Humez S, Sergeant N, Schraen-Maschke S, Muhr-Tailleux A, Hamdane M, Buée L, Blum D (2011) Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology. Neurobiol. Dis. 43, 486-494.
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 486-494
-
-
Belarbi, K.1
Burnouf, S.2
Fernandez-Gomez, F.J.3
Laurent, C.4
Lestavel, S.5
Figeac, M.6
Sultan, A.7
Troquier, L.8
Leboucher, A.9
Caillierez, R.10
Grosjean, M.E.11
Demeyer, D.12
Obriot, H.13
Brion, I.14
Barbot, B.15
Galas, M.C.16
Staels, B.17
Humez, S.18
Sergeant, N.19
Schraen-Maschke, S.20
Muhr-Tailleux, A.21
Hamdane, M.22
Buée, L.23
Blum, D.24
more..
-
12
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
Blüher M, Kahn BB, Kahn CR (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299, 572-574.
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Blüher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
13
-
-
84862776702
-
A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Bostrom EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BM (2012) A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481, 463-468.
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Boström, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
Rasbach, K.A.7
Bostrom, E.A.8
Choi, J.H.9
Long, J.Z.10
Kajimura, S.11
Zingaretti, M.C.12
Vind, B.F.13
Tu, H.14
Cinti, S.15
Højlund, K.16
Gygi, S.P.17
Spiegelman, B.M.18
-
14
-
-
77953495952
-
Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy
-
Brault JJ, Jespersen JG, Goldberg AL (2010) Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy. J. Biol. Chem. 285, 19460-19471.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 19460-19471
-
-
Brault, J.J.1
Jespersen, J.G.2
Goldberg, A.L.3
-
15
-
-
79960209054
-
LIF is a contraction-induced myokine stimulating human myocyte proliferation
-
Broholm C, Laye MJ, Brandt C, Vadalasetty R, Pilegaard H, Pedersen BK, Scheele C (2011) LIF is a contraction-induced myokine stimulating human myocyte proliferation. J. Appl. Physiol. 111, 251-259.
-
(2011)
J. Appl. Physiol.
, vol.111
, pp. 251-259
-
-
Broholm, C.1
Laye, M.J.2
Brandt, C.3
Vadalasetty, R.4
Pilegaard, H.5
Pedersen, B.K.6
Scheele, C.7
-
16
-
-
33748175583
-
The evolution of aging and age-related physical decline in mice selectively bred for high voluntary exercise
-
Bronikowski AM, Morgan TJ, Garland T Jr, Carter PA (2006) The evolution of aging and age-related physical decline in mice selectively bred for high voluntary exercise. Evolution 60, 1494-1508.
-
(2006)
Evolution
, vol.60
, pp. 1494-1508
-
-
Bronikowski, A.M.1
Morgan, T.J.2
Garland Jr., T.3
Carter, P.A.4
-
17
-
-
0037799688
-
Dissociation between functional senescence and oxidative stress resistance in Drosophila
-
Cook-Wiens E, Grotewiel MS (2002) Dissociation between functional senescence and oxidative stress resistance in Drosophila. Exp. Gerontol. 37, 1347-1357.
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 1347-1357
-
-
Cook-Wiens, E.1
Grotewiel, M.S.2
-
18
-
-
78650918920
-
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
-
Demontis F, Perrimon N (2010) FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 143, 813-825.
-
(2010)
Cell
, vol.143
, pp. 813-825
-
-
Demontis, F.1
Perrimon, N.2
-
19
-
-
78049438081
-
The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles
-
Duteil D, Chambon C, Ali F, Malivindi R, Zoll J, Kato S, Geny B, Chambon P, Metzger D (2010) The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles. Cell Metab. 12, 496-508.
-
(2010)
Cell Metab.
, vol.12
, pp. 496-508
-
-
Duteil, D.1
Chambon, C.2
Ali, F.3
Malivindi, R.4
Zoll, J.5
Kato, S.6
Geny, B.7
Chambon, P.8
Metzger, D.9
-
20
-
-
81255157471
-
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
-
Ellingsgaard H, Hauselmann I, Schuler B, Habib AM, Baggio LL, Meier DT, Eppler E, Bouzakri K, Wueest S, Muller YD, Hansen AM, Reinecke M, Konrad D, Gassmann M, Reimann F, Halban PA, Gromada J, Drucker DJ, Gribble FM, Ehses JA, Donath MY (2011) Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat. Med. 17, 1481-1489.
-
(2011)
Nat. Med.
, vol.17
, pp. 1481-1489
-
-
Ellingsgaard, H.1
Hauselmann, I.2
Schuler, B.3
Habib, A.M.4
Baggio, L.L.5
Meier, D.T.6
Eppler, E.7
Bouzakri, K.8
Wueest, S.9
Muller, Y.D.10
Hansen, A.M.11
Reinecke, M.12
Konrad, D.13
Gassmann, M.14
Reimann, F.15
Halban, P.A.16
Gromada, J.17
Drucker, D.J.18
Gribble, F.M.19
Ehses, J.A.20
Donath, M.Y.21
more..
-
21
-
-
33750345334
-
Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects
-
Feldman BJ, Streeper RS, Farese RV Jr, Yamamoto KR (2006) Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects. Proc. Natl Acad. Sci. USA 103, 15675-15680.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 15675-15680
-
-
Feldman, B.J.1
Streeper, R.S.2
Farese Jr., R.V.3
Yamamoto, K.R.4
-
22
-
-
25644432665
-
Age-related modifications in circulating IL-15 levels in humans
-
Gangemi S, Basile G, Monti D, Merendino RA, Di Pasquale G, Bisignano U, Nicita-Mauro V, Franceschi C (2005) Age-related modifications in circulating IL-15 levels in humans. Mediators Inflamm. 2005, 245-247.
-
(2005)
Mediators Inflamm.
, vol.2005
, pp. 245-247
-
-
Gangemi, S.1
Basile, G.2
Monti, D.3
Merendino, R.A.4
Di Pasquale, G.5
Bisignano, U.6
Nicita-Mauro, V.7
Franceschi, C.8
-
23
-
-
77953218871
-
Age- and temperature-dependent somatic mutation accumulation in Drosophila melanogaster
-
Garcia AM, Calder RB, Dolle ME, Lundell M, Kapahi P, Vijg J (2010) Age- and temperature-dependent somatic mutation accumulation in Drosophila melanogaster. PLoS Genet. 6, e1000950.
-
(2010)
PLoS Genet.
, vol.6
-
-
Garcia, A.M.1
Calder, R.B.2
Dolle, M.E.3
Lundell, M.4
Kapahi, P.5
Vijg, J.6
-
24
-
-
79957791224
-
Physical exercise protects against Alzheimer's disease in 3xTg-AD mice
-
Garcia-Mesa Y, Lopez-Ramos JC, Gimenez-Llort L, Revilla S, Guerra R, Gruart A, Laferla FM, Cristofol R, Delgado-Garcia JM, Sanfeliu C (2011) Physical exercise protects against Alzheimer's disease in 3xTg-AD mice. J. Alzheimers Dis. 24, 421-454.
-
(2011)
J. Alzheimers Dis.
, vol.24
, pp. 421-454
-
-
Garcia-Mesa, Y.1
Lopez-Ramos, J.C.2
Gimenez-Llort, L.3
Revilla, S.4
Guerra, R.5
Gruart, A.6
Laferla, F.M.7
Cristofol, R.8
Delgado-Garcia, J.M.9
Sanfeliu, C.10
-
25
-
-
20144366852
-
Rapid iterative negative geotaxis (RING): a new method for assessing age-related locomotor decline in Drosophila
-
Gargano JW, Martin I, Bhandari P, Grotewiel MS (2005) Rapid iterative negative geotaxis (RING): a new method for assessing age-related locomotor decline in Drosophila. Exp. Gerontol. 40, 386-395.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 386-395
-
-
Gargano, J.W.1
Martin, I.2
Bhandari, P.3
Grotewiel, M.S.4
-
26
-
-
0036021375
-
Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation
-
Garigan D, Hsu AL, Fraser AG, Kamath RS, Ahringer J, Kenyon C (2002) Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 161, 1101-1112.
-
(2002)
Genetics
, vol.161
, pp. 1101-1112
-
-
Garigan, D.1
Hsu, A.L.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Kenyon, C.6
-
27
-
-
36448950118
-
Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease
-
Gates AC, Bernal-Mizrachi C, Chinault SL, Feng C, Schneider JG, Coleman T, Malone JP, Townsend RR, Chakravarthy MV, Semenkovich CF (2007) Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease. Cell Metab. 6, 497-505.
-
(2007)
Cell Metab.
, vol.6
, pp. 497-505
-
-
Gates, A.C.1
Bernal-Mizrachi, C.2
Chinault, S.L.3
Feng, C.4
Schneider, J.G.5
Coleman, T.6
Malone, J.P.7
Townsend, R.R.8
Chakravarthy, M.V.9
Semenkovich, C.F.10
-
28
-
-
33745512110
-
Specific age-related signatures in Drosophila body parts transcriptome
-
Girardot F, Lasbleiz C, Monnier V, Tricoire H (2006) Specific age-related signatures in Drosophila body parts transcriptome. BMC Genomics 7, 69.
-
(2006)
BMC Genomics
, vol.7
, pp. 69
-
-
Girardot, F.1
Lasbleiz, C.2
Monnier, V.3
Tricoire, H.4
-
29
-
-
82855169509
-
Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI deficient muscles
-
Grumati P, Coletto L, Schiavinato A, Castagnaro S, Bertaggia E, Sandri M, Bonaldo P (2011) Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI deficient muscles. Autophagy 7, 1415-1423.
-
(2011)
Autophagy
, vol.7
, pp. 1415-1423
-
-
Grumati, P.1
Coletto, L.2
Schiavinato, A.3
Castagnaro, S.4
Bertaggia, E.5
Sandri, M.6
Bonaldo, P.7
-
30
-
-
63349107479
-
Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity
-
Guo T, Jou W, Chanturiya T, Portas J, Gavrilova O, McPherron AC (2009) Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity. PLoS ONE 4, e4937.
-
(2009)
PLoS ONE
, vol.4
-
-
Guo, T.1
Jou, W.2
Chanturiya, T.3
Portas, J.4
Gavrilova, O.5
McPherron, A.C.6
-
31
-
-
41949090708
-
Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors
-
Haidet AM, Rizo L, Handy C, Umapathi P, Eagle A, Shilling C, Boue D, Martin PT, Sahenk Z, Mendell JR, Kaspar BK (2008) Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors. Proc. Natl Acad. Sci. USA 105, 4318-4322.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4318-4322
-
-
Haidet, A.M.1
Rizo, L.2
Handy, C.3
Umapathi, P.4
Eagle, A.5
Shilling, C.6
Boue, D.7
Martin, P.T.8
Sahenk, Z.9
Mendell, J.R.10
Kaspar, B.K.11
-
32
-
-
36348972777
-
Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse
-
Hakimi P, Yang J, Casadesus G, Massillon D, Tolentino-Silva F, Nye CK, Cabrera ME, Hagen DR, Utter CB, Baghdy Y, Johnson DH, Wilson DL, Kirwan JP, Kalhan SC, Hanson RW (2007) Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J. Biol. Chem. 282, 32844-32855.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32844-32855
-
-
Hakimi, P.1
Yang, J.2
Casadesus, G.3
Massillon, D.4
Tolentino-Silva, F.5
Nye, C.K.6
Cabrera, M.E.7
Hagen, D.R.8
Utter, C.B.9
Baghdy, Y.10
Johnson, D.H.11
Wilson, D.L.12
Kirwan, J.P.13
Kalhan, S.C.14
Hanson, R.W.15
-
33
-
-
35648937073
-
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals
-
Handschin C, Chin S, Li P, Liu F, Maratos-Flier E, Lebrasseur NK, Yan Z, Spiegelman BM (2007a) Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J. Biol. Chem. 282, 30014-30021.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30014-30021
-
-
Handschin, C.1
Chin, S.2
Li, P.3
Liu, F.4
Maratos-Flier, E.5
Lebrasseur, N.K.6
Yan, Z.7
Spiegelman, B.M.8
-
34
-
-
36048931015
-
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk
-
Handschin C, Choi CS, Chin S, Kim S, Kawamori D, Kurpad AJ, Neubauer N, Hu J, Mootha VK, Kim YB, Kulkarni RN, Shulman GI, Spiegelman BM (2007b) Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk. J. Clin. Invest. 117, 3463-3474.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3463-3474
-
-
Handschin, C.1
Choi, C.S.2
Chin, S.3
Kim, S.4
Kawamori, D.5
Kurpad, A.J.6
Neubauer, N.7
Hu, J.8
Mootha, V.K.9
Kim, Y.B.10
Kulkarni, R.N.11
Shulman, G.I.12
Spiegelman, B.M.13
-
35
-
-
44449133522
-
Born to run; the story of the PEPCK-Cmus mouse
-
Hanson RW, Hakimi P (2008) Born to run; the story of the PEPCK-Cmus mouse. Biochimie 90, 838-842.
-
(2008)
Biochimie
, vol.90
, pp. 838-842
-
-
Hanson, R.W.1
Hakimi, P.2
-
36
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, Gilpin C, Xiao G, Bassel-Duby R, Scherer PE, Levine B (2012) Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 481, 511-515.
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
Bassik, M.C.2
Moresi, V.3
Sun, K.4
Wei, Y.5
Zou, Z.6
An, Z.7
Loh, J.8
Fisher, J.9
Sun, Q.10
Korsmeyer, S.11
Packer, M.12
May, H.I.13
Hill, J.A.14
Virgin, H.W.15
Gilpin, C.16
Xiao, G.17
Bassel-Duby, R.18
Scherer, P.E.19
Levine, B.20
more..
-
37
-
-
84870912911
-
E-peptides control bioavailability of IGF-1
-
Hede MS, Salimova E, Piszczek A, Perlas E, Winn N, Nastasi T, Rosenthal N (2012) E-peptides control bioavailability of IGF-1. PLoS ONE 7, e51152.
-
(2012)
PLoS ONE
, vol.7
-
-
Hede, M.S.1
Salimova, E.2
Piszczek, A.3
Perlas, E.4
Winn, N.5
Nastasi, T.6
Rosenthal, N.7
-
38
-
-
78149306422
-
Dynamics of the skeletal muscle secretome during myoblast differentiation
-
Henningsen J, Rigbolt KT, Blagoev B, Pedersen BK, Kratchmarova I (2010) Dynamics of the skeletal muscle secretome during myoblast differentiation. Mol. Cell. Proteomics 9, 2482-2496.
-
(2010)
Mol. Cell. Proteomics
, vol.9
, pp. 2482-2496
-
-
Henningsen, J.1
Rigbolt, K.T.2
Blagoev, B.3
Pedersen, B.K.4
Kratchmarova, I.5
-
39
-
-
0037167855
-
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
-
Herndon LA, Schmeissner PJ, Dudaronek JM, Brown PA, Listner KM, Sakano Y, Paupard MC, Hall DH, Driscoll M (2002) Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419, 808-814.
-
(2002)
Nature
, vol.419
, pp. 808-814
-
-
Herndon, L.A.1
Schmeissner, P.J.2
Dudaronek, J.M.3
Brown, P.A.4
Listner, K.M.5
Sakano, Y.6
Paupard, M.C.7
Hall, D.H.8
Driscoll, M.9
-
40
-
-
80052067994
-
Exercise-induced muscle-derived cytokines inhibit mammary cancer cell growth
-
Hojman P, Dethlefsen C, Brandt C, Hansen J, Pedersen L, Pedersen BK (2011) Exercise-induced muscle-derived cytokines inhibit mammary cancer cell growth. Am. J. Physiol. Endocrinol. Metab. 301, E504-E510.
-
(2011)
Am. J. Physiol. Endocrinol. Metab.
, vol.301
-
-
Hojman, P.1
Dethlefsen, C.2
Brandt, C.3
Hansen, J.4
Pedersen, L.5
Pedersen, B.K.6
-
41
-
-
0024226812
-
Exercise and longevity: studies on rats
-
Holloszy JO (1988) Exercise and longevity: studies on rats. J. Gerontol. 43, B149-B151.
-
(1988)
J. Gerontol.
, vol.43
-
-
Holloszy, J.O.1
-
42
-
-
0027252538
-
Exercise increases average longevity of female rats despite increased food intake and no growth retardation
-
Holloszy JO (1993) Exercise increases average longevity of female rats despite increased food intake and no growth retardation. J. Gerontol. 48, B97-B100.
-
(1993)
J. Gerontol.
, vol.48
-
-
Holloszy, J.O.1
-
43
-
-
2942563805
-
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
-
Hwangbo DS, Gershman B, Tu MP, Palmer M, Tatar M (2004) Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 429, 562-566.
-
(2004)
Nature
, vol.429
, pp. 562-566
-
-
Hwangbo, D.S.1
Gershman, B.2
Tu, M.P.3
Palmer, M.4
Tatar, M.5
-
44
-
-
54849438574
-
FGF21 is an Akt-regulated myokine
-
Izumiya Y, Bina HA, Ouchi N, Akasaki Y, Kharitonenkov A, Walsh K (2008) FGF21 is an Akt-regulated myokine. FEBS Lett. 582, 3805-3810.
-
(2008)
FEBS Lett.
, vol.582
, pp. 3805-3810
-
-
Izumiya, Y.1
Bina, H.A.2
Ouchi, N.3
Akasaki, Y.4
Kharitonenkov, A.5
Walsh, K.6
-
45
-
-
0029994377
-
Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism
-
James PL, Stewart CE, Rotwein P (1996) Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism. J. Cell Biol. 133, 683-693.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 683-693
-
-
James, P.L.1
Stewart, C.E.2
Rotwein, P.3
-
46
-
-
84863514544
-
intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster
-
Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon N, Melov S, Kapahi P (2012) intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metab. 16, 97-103.
-
(2012)
Cell Metab.
, vol.16
, pp. 97-103
-
-
Katewa, S.D.1
Demontis, F.2
Kolipinski, M.3
Hubbard, A.4
Gill, M.S.5
Perrimon, N.6
Melov, S.7
Kapahi, P.8
-
47
-
-
78651269800
-
Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice
-
Keipert S, Voigt A, Klaus S (2011) Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice. Aging Cell 10, 122-136.
-
(2011)
Aging Cell
, vol.10
, pp. 122-136
-
-
Keipert, S.1
Voigt, A.2
Klaus, S.3
-
48
-
-
84874546118
-
Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system
-
Keipert S, Ost M, Chadt A, Voigt A, Ayala V, Portero-Otin M, Pamplona R, Al-Hasani H, Klaus S (2013) Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system. Am. J. Physiol. Endocrinol. Metab. 304, E495-E506.
-
(2013)
Am. J. Physiol. Endocrinol. Metab.
, vol.304
-
-
Keipert, S.1
Ost, M.2
Chadt, A.3
Voigt, A.4
Ayala, V.5
Portero-Otin, M.6
Pamplona, R.7
Al-Hasani, H.8
Klaus, S.9
-
49
-
-
0035651023
-
Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content
-
Keller C, Steensberg A, Pilegaard H, Osada T, Saltin B, Pedersen BK, Neufer PD (2001) Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content. FASEB J. 15, 2748-2750.
-
(2001)
FASEB J.
, vol.15
, pp. 2748-2750
-
-
Keller, C.1
Steensberg, A.2
Pilegaard, H.3
Osada, T.4
Saltin, B.5
Pedersen, B.K.6
Neufer, P.D.7
-
50
-
-
63849172657
-
FGF21: a novel prospect for the treatment of metabolic diseases
-
Kharitonenkov A, Shanafelt AB (2009) FGF21: a novel prospect for the treatment of metabolic diseases. Curr. Opin. Investig. Drugs 10, 359-364.
-
(2009)
Curr. Opin. Investig. Drugs
, vol.10
, pp. 359-364
-
-
Kharitonenkov, A.1
Shanafelt, A.B.2
-
51
-
-
33644755633
-
Interleukin-6 and diabetes: the good, the bad, or the indifferent?
-
Kristiansen OP, Mandrup-Poulsen T (2005) Interleukin-6 and diabetes: the good, the bad, or the indifferent? Diabetes 54, S114-S124.
-
(2005)
Diabetes
, vol.54
-
-
Kristiansen, O.P.1
Mandrup-Poulsen, T.2
-
52
-
-
84856695688
-
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
-
Lavasani M, Robinson AR, Lu A, Song M, Feduska JM, Ahani B, Tilstra JS, Feldman CH, Robbins PD, Niedernhofer LJ, Huard J (2012) Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model. Nat. Commun. 3, 608.
-
(2012)
Nat. Commun.
, vol.3
, pp. 608
-
-
Lavasani, M.1
Robinson, A.R.2
Lu, A.3
Song, M.4
Feduska, J.M.5
Ahani, B.6
Tilstra, J.S.7
Feldman, C.H.8
Robbins, P.D.9
Niedernhofer, L.J.10
Huard, J.11
-
53
-
-
68949108753
-
Myostatin inhibition enhances the effects of exercise on performance and metabolic outcomes in aged mice
-
LeBrasseur NK, Schelhorn TM, Bernardo BL, Cosgrove PG, Loria PM, Brown TA (2009) Myostatin inhibition enhances the effects of exercise on performance and metabolic outcomes in aged mice. J. Gerontol. A Biol. Sci. Med. Sci. 64, 940-948.
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.64
, pp. 940-948
-
-
LeBrasseur, N.K.1
Schelhorn, T.M.2
Bernardo, B.L.3
Cosgrove, P.G.4
Loria, P.M.5
Brown, T.A.6
-
54
-
-
0347285363
-
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
-
Lecker SH, Jagoe RT, Gilbert A, Gomes M, Baracos V, Bailey J, Price SR, Mitch WE, Goldberg AL (2004) Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. Faseb J. 18, 39-51.
-
(2004)
Faseb J.
, vol.18
, pp. 39-51
-
-
Lecker, S.H.1
Jagoe, R.T.2
Gilbert, A.3
Gomes, M.4
Baracos, V.5
Bailey, J.6
Price, S.R.7
Mitch, W.E.8
Goldberg, A.L.9
-
55
-
-
8444243360
-
Regulation of muscle mass by myostatin
-
Lee SJ (2004) Regulation of muscle mass by myostatin. Annu. Rev. Cell Dev. Biol. 20, 61-86.
-
(2004)
Annu. Rev. Cell Dev. Biol.
, vol.20
, pp. 61-86
-
-
Lee, S.J.1
-
56
-
-
0345447590
-
Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
-
Libina N, Berman JR, Kenyon C (2003) Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115, 489-502.
-
(2003)
Cell
, vol.115
, pp. 489-502
-
-
Libina, N.1
Berman, J.R.2
Kenyon, C.3
-
57
-
-
0020622536
-
The effects of enforced running on the gastrocnemius muscle in aging mice: an ultrastructural study
-
Ludatscher R, Silbermann M, Gershon D, Reznick A (1983) The effects of enforced running on the gastrocnemius muscle in aging mice: an ultrastructural study. Exp. Gerontol. 18, 113-123.
-
(1983)
Exp. Gerontol.
, vol.18
, pp. 113-123
-
-
Ludatscher, R.1
Silbermann, M.2
Gershon, D.3
Reznick, A.4
-
58
-
-
33644682192
-
Flight activity, mortality rates, and lipoxidative damage in Drosophila
-
Magwere T, Pamplona R, Miwa S, Martinez-Diaz P, Portero-Otin M, Brand MD, Partridge L (2006) Flight activity, mortality rates, and lipoxidative damage in Drosophila. J. Gerontol. A Biol. Sci. Med. Sci. 61, 136-145.
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 136-145
-
-
Magwere, T.1
Pamplona, R.2
Miwa, S.3
Martinez-Diaz, P.4
Portero-Otin, M.5
Brand, M.D.6
Partridge, L.7
-
59
-
-
67649366540
-
Sod2 knockdown in the musculature has whole-organism consequences in Drosophila
-
Martin I, Jones MA, Rhodenizer D, Zheng J, Warrick JM, Seroude L, Grotewiel M (2009) Sod2 knockdown in the musculature has whole-organism consequences in Drosophila. Free Radic. Biol. Med. 47, 803-813.
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 803-813
-
-
Martin, I.1
Jones, M.A.2
Rhodenizer, D.3
Zheng, J.4
Warrick, J.M.5
Seroude, L.6
Grotewiel, M.7
-
62
-
-
73949131481
-
Effects of myostatin deletion in aging mice
-
Morissette MR, Stricker JC, Rosenberg MA, Buranasombati C, Levitan EB, Mittleman MA, Rosenzweig A (2009) Effects of myostatin deletion in aging mice. Aging Cell 8, 573-583.
-
(2009)
Aging Cell
, vol.8
, pp. 573-583
-
-
Morissette, M.R.1
Stricker, J.C.2
Rosenberg, M.A.3
Buranasombati, C.4
Levitan, E.B.5
Mittleman, M.A.6
Rosenzweig, A.7
-
63
-
-
20544440861
-
Aging muscle
-
Nair KS (2005) Aging muscle. Am. J. Clin. Nutr. 81, 953-963.
-
(2005)
Am. J. Clin. Nutr.
, vol.81
, pp. 953-963
-
-
Nair, K.S.1
-
64
-
-
2442540309
-
Musclin, a novel skeletal muscle-derived secretory factor
-
Nishizawa H, Matsuda M, Yamada Y, Kawai K, Suzuki E, Makishima M, Kitamura T, Shimomura I (2004) Musclin, a novel skeletal muscle-derived secretory factor. J. Biol. Chem. 279, 19391-19395.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19391-19395
-
-
Nishizawa, H.1
Matsuda, M.2
Yamada, Y.3
Kawai, K.4
Suzuki, E.5
Makishima, M.6
Kitamura, T.7
Shimomura, I.8
-
65
-
-
80054963118
-
Proteomic identification of secreted proteins from human skeletal muscle cells and expression in response to strength training
-
Norheim F, Raastad T, Thiede B, Rustan AC, Drevon CA, Haugen F (2011) Proteomic identification of secreted proteins from human skeletal muscle cells and expression in response to strength training. Am. J. Physiol. Endocrinol. Metab. 301, E1013-E1021.
-
(2011)
Am. J. Physiol. Endocrinol. Metab.
, vol.301
-
-
Norheim, F.1
Raastad, T.2
Thiede, B.3
Rustan, A.C.4
Drevon, C.A.5
Haugen, F.6
-
66
-
-
0031895668
-
Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running
-
Ostrowski K, Rohde T, Zacho M, Asp S, Pedersen BK (1998) Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running. J. Physiol. 508, 949-953.
-
(1998)
J. Physiol.
, vol.508
, pp. 949-953
-
-
Ostrowski, K.1
Rohde, T.2
Zacho, M.3
Asp, S.4
Pedersen, B.K.5
-
67
-
-
57749107636
-
Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism
-
Ouchi N, Oshima Y, Ohashi K, Higuchi A, Ikegami C, Izumiya Y, Walsh K (2008) Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism. J. Biol. Chem. 283, 32802-32811.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 32802-32811
-
-
Ouchi, N.1
Oshima, Y.2
Ohashi, K.3
Higuchi, A.4
Ikegami, C.5
Izumiya, Y.6
Walsh, K.7
-
68
-
-
68149169938
-
Signals of youth: endocrine regulation of aging in Caenorhabditis elegans
-
Panowski SH, Dillin A (2009) Signals of youth: endocrine regulation of aging in Caenorhabditis elegans. Trends Endocrinol. Metab. 20, 259-264.
-
(2009)
Trends Endocrinol. Metab.
, vol.20
, pp. 259-264
-
-
Panowski, S.H.1
Dillin, A.2
-
70
-
-
33751198463
-
Increased Rheb-TOR signaling enhances sensitivity of the whole organism to oxidative stress
-
Patel PH, Tamanoi F (2006) Increased Rheb-TOR signaling enhances sensitivity of the whole organism to oxidative stress. J. Cell Sci. 119, 4285-4292.
-
(2006)
J. Cell Sci.
, vol.119
, pp. 4285-4292
-
-
Patel, P.H.1
Tamanoi, F.2
-
71
-
-
84864283300
-
Muscles, exercise and obesity: skeletal muscle as a secretory organ
-
Pedersen BK, Febbraio MA (2012) Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat. Rev. Endocrinol. 8, 457-465.
-
(2012)
Nat. Rev. Endocrinol.
, vol.8
, pp. 457-465
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
72
-
-
84859469390
-
Muscle-derived expression of the chemokine CXCL1 attenuates diet-induced obesity and improves fatty acid oxidation in the muscle
-
Pedersen L, Olsen CH, Pedersen BK, Hojman P (2012) Muscle-derived expression of the chemokine CXCL1 attenuates diet-induced obesity and improves fatty acid oxidation in the muscle. Am. J. Physiol. Endocrinol. Metab. 302, E831-E840.
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.302
-
-
Pedersen, L.1
Olsen, C.H.2
Pedersen, B.K.3
Hojman, P.4
-
73
-
-
34250738329
-
Age-dependent stability of sensorimotor functions in the life-extended Drosophila mutant methuselah
-
Petrosyan A, Hsieh IH, Saberi K (2007) Age-dependent stability of sensorimotor functions in the life-extended Drosophila mutant methuselah. Behav. Genet. 37, 585-594.
-
(2007)
Behav. Genet.
, vol.37
, pp. 585-594
-
-
Petrosyan, A.1
Hsieh, I.H.2
Saberi, K.3
-
74
-
-
67650002155
-
Exercise-training in young Drosophila melanogaster reduces age-related decline in mobility and cardiac performance
-
Piazza N, Gosangi B, Devilla S, Arking R, Wessells R (2009) Exercise-training in young Drosophila melanogaster reduces age-related decline in mobility and cardiac performance. PLoS ONE 4, e5886.
-
(2009)
PLoS ONE
, vol.4
-
-
Piazza, N.1
Gosangi, B.2
Devilla, S.3
Arking, R.4
Wessells, R.5
-
75
-
-
35548999739
-
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes
-
Pospisilik JA, Knauf C, Joza N, Benit P, Orthofer M, Cani PD, Ebersberger I, Nakashima T, Sarao R, Neely G, Esterbauer H, Kozlov A, Kahn CR, Kroemer G, Rustin P, Burcelin R, Penninger JM (2007) Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell 131, 476-491.
-
(2007)
Cell
, vol.131
, pp. 476-491
-
-
Pospisilik, J.A.1
Knauf, C.2
Joza, N.3
Benit, P.4
Orthofer, M.5
Cani, P.D.6
Ebersberger, I.7
Nakashima, T.8
Sarao, R.9
Neely, G.10
Esterbauer, H.11
Kozlov, A.12
Kahn, C.R.13
Kroemer, G.14
Rustin, P.15
Burcelin, R.16
Penninger, J.M.17
-
76
-
-
84871674116
-
IL-15 overexpression promotes endurance, oxidative energy metabolism, and muscle PPARδ, SIRT1, PGC-1α, and PGC-1β expression in male mice
-
Quinn LS, Anderson BG, Conner JD, Wolden-Hanson T (2013) IL-15 overexpression promotes endurance, oxidative energy metabolism, and muscle PPARδ, SIRT1, PGC-1α, and PGC-1β expression in male mice. Endocrinology 154, 232-245.
-
(2013)
Endocrinology
, vol.154
, pp. 232-245
-
-
Quinn, L.S.1
Anderson, B.G.2
Conner, J.D.3
Wolden-Hanson, T.4
-
77
-
-
47649097993
-
Association between muscular strength and mortality in men: prospective cohort study
-
Ruiz JR, Sui X, Lobelo F, Morrow JR Jr, Jackson AW, Sjöström M, Blair SN (2008) Association between muscular strength and mortality in men: prospective cohort study. BMJ 337, a439.
-
(2008)
BMJ
, vol.337
-
-
Ruiz, J.R.1
Sui, X.2
Lobelo, F.3
Morrow Jr., J.R.4
Jackson, A.W.5
Sjöström, M.6
Blair, S.N.7
-
78
-
-
79951952404
-
Strenuous endurance exercise improves life expectancy: it's in our genes
-
Ruiz JR, Moran M, Arenas J, Lucia A (2011) Strenuous endurance exercise improves life expectancy: it's in our genes. Br. J. Sports Med. 45, 159-161.
-
(2011)
Br. J. Sports Med.
, vol.45
, pp. 159-161
-
-
Ruiz, J.R.1
Moran, M.2
Arenas, J.3
Lucia, A.4
-
80
-
-
79952753140
-
Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice
-
Safdar A, Bourgeois JM, Ogborn DI, Little JP, Hettinga BP, Akhtar M, Thompson JE, Melov S, Mocellin NJ, Kujoth GC, Prolla TA, Tarnopolsky MA (2011) Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice. Proc. Natl Acad. Sci. USA 108, 4135-4140.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 4135-4140
-
-
Safdar, A.1
Bourgeois, J.M.2
Ogborn, D.I.3
Little, J.P.4
Hettinga, B.P.5
Akhtar, M.6
Thompson, J.E.7
Melov, S.8
Mocellin, N.J.9
Kujoth, G.C.10
Prolla, T.A.11
Tarnopolsky, M.A.12
-
81
-
-
66749167618
-
Smad2 and 3 transcription factors control muscle mass in adulthood
-
Sartori R, Milan G, Patron M, Mammucari C, Blaauw B, Abraham R, Sandri M (2009) Smad2 and 3 transcription factors control muscle mass in adulthood. Am. J. Physiol. Cell Physiol. 296, C1248-C1257.
-
(2009)
Am. J. Physiol. Cell Physiol.
, vol.296
-
-
Sartori, R.1
Milan, G.2
Patron, M.3
Mammucari, C.4
Blaauw, B.5
Abraham, R.6
Sandri, M.7
-
82
-
-
84859488137
-
Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis
-
Seldin MM, Peterson JM, Byerly MS, Wei Z, Wong GW (2012) Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis. J. Biol. Chem. 287, 11968-11980.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 11968-11980
-
-
Seldin, M.M.1
Peterson, J.M.2
Byerly, M.S.3
Wei, Z.4
Wong, G.W.5
-
83
-
-
0028911421
-
Skeletal muscle cell-derived insulin-like growth factor (IGF) binding proteins inhibit IGF-I-induced myogenesis in rat L6E9 cells
-
Silverman LA, Cheng ZQ, Hsiao D, Rosenthal SM (1995) Skeletal muscle cell-derived insulin-like growth factor (IGF) binding proteins inhibit IGF-I-induced myogenesis in rat L6E9 cells. Endocrinology 136, 720-726.
-
(1995)
Endocrinology
, vol.136
, pp. 720-726
-
-
Silverman, L.A.1
Cheng, Z.Q.2
Hsiao, D.3
Rosenthal, S.M.4
-
84
-
-
33750527757
-
Prolonged absence of myostatin reduces sarcopenia
-
Siriett V, Platt L, Salerno MS, Ling N, Kambadur R, Sharma M (2006) Prolonged absence of myostatin reduces sarcopenia. J. Cell. Physiol. 209, 866-873.
-
(2006)
J. Cell. Physiol.
, vol.209
, pp. 866-873
-
-
Siriett, V.1
Platt, L.2
Salerno, M.S.3
Ling, N.4
Kambadur, R.5
Sharma, M.6
-
85
-
-
0037304275
-
Skeletal muscle IGF-binding protein-3 and -5 expressions are age, muscle, and load dependent
-
Spangenburg EE, Abraha T, Childs TE, Pattison JS, Booth FW (2003) Skeletal muscle IGF-binding protein-3 and -5 expressions are age, muscle, and load dependent. Am. J. Physiol. Endocrinol. Metab. 284, E340-E350.
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.284
-
-
Spangenburg, E.E.1
Abraha, T.2
Childs, T.E.3
Pattison, J.S.4
Booth, F.W.5
-
86
-
-
62749136195
-
Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans
-
Staiger H, Haas C, Machann J, Werner R, Weisser M, Schick F, Machicao F, Stefan N, Fritsche A, Häring HU (2009) Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. Diabetes 58, 579-589.
-
(2009)
Diabetes
, vol.58
, pp. 579-589
-
-
Staiger, H.1
Haas, C.2
Machann, J.3
Werner, R.4
Weisser, M.5
Schick, F.6
Machicao, F.7
Stefan, N.8
Fritsche, A.9
Häring, H.U.10
-
87
-
-
84872137308
-
Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies
-
Stenesen D, Suh JM, Seo J, Yu K, Lee KS, Kim JS, Min KJ, Graff JM (2013) Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies. Cell Metab. 17, 101-112.
-
(2013)
Cell Metab.
, vol.17
, pp. 101-112
-
-
Stenesen, D.1
Suh, J.M.2
Seo, J.3
Yu, K.4
Lee, K.S.5
Kim, J.S.6
Min, K.J.7
Graff, J.M.8
-
88
-
-
77953036663
-
Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: susceptibility of skeletal muscles to oxidative injury
-
Szczesny B, Tann AW, Mitra S (2011) Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: susceptibility of skeletal muscles to oxidative injury. Mech. Ageing Dev. 131, 330-337.
-
(2011)
Mech. Ageing Dev.
, vol.131
, pp. 330-337
-
-
Szczesny, B.1
Tann, A.W.2
Mitra, S.3
-
89
-
-
34547097247
-
Brain IRS2 signaling coordinates life span and nutrient homeostasis
-
Taguchi A, Wartschow LM, White MF (2007) Brain IRS2 signaling coordinates life span and nutrient homeostasis. Science 317, 369-372.
-
(2007)
Science
, vol.317
, pp. 369-372
-
-
Taguchi, A.1
Wartschow, L.M.2
White, M.F.3
-
90
-
-
77949872870
-
A critical role of SNF1A/dAMPKalpha (Drosophila AMP-activated protein kinase alpha) in muscle on longevity and stress resistance in Drosophila melanogaster
-
Tohyama D, Yamaguchi A (2010) A critical role of SNF1A/dAMPKalpha (Drosophila AMP-activated protein kinase alpha) in muscle on longevity and stress resistance in Drosophila melanogaster. Biochem. Biophys. Res. Commun. 394, 112-118.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.394
, pp. 112-118
-
-
Tohyama, D.1
Yamaguchi, A.2
-
91
-
-
79955040521
-
Flight restriction prevents associative learning deficits but not changes in brain protein-adduct formation during honeybee ageing
-
Tolfsen CC, Baker N, Kreibich C, Amdam GV (2011) Flight restriction prevents associative learning deficits but not changes in brain protein-adduct formation during honeybee ageing. J. Exp. Biol. 214, 1322-1332.
-
(2011)
J. Exp. Biol.
, vol.214
, pp. 1322-1332
-
-
Tolfsen, C.C.1
Baker, N.2
Kreibich, C.3
Amdam, G.V.4
-
93
-
-
80054722470
-
A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila
-
Vrailas-Mortimer A, Del Rivero T, Mukherjee S, Nag S, Gaitanidis A, Kadas D, Consoulas C, Duttaroy A, Sanyal S (2011) A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila. Dev. Cell 21, 783-795.
-
(2011)
Dev. Cell
, vol.21
, pp. 783-795
-
-
Vrailas-Mortimer, A.1
Del Rivero, T.2
Mukherjee, S.3
Nag, S.4
Gaitanidis, A.5
Kadas, D.6
Consoulas, C.7
Duttaroy, A.8
Sanyal, S.9
-
94
-
-
0024593922
-
Muscular contraction stimulates posterior hypothalamic neurons
-
Waldrop TG, Stremel RW (1989) Muscular contraction stimulates posterior hypothalamic neurons. Am. J. Physiol. 256, R348-R356.
-
(1989)
Am. J. Physiol.
, vol.256
-
-
Waldrop, T.G.1
Stremel, R.W.2
-
95
-
-
84860347786
-
Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation
-
Wang Q, McPherron AC (2012) Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation. J. Physiol. 590, 2151-2165.
-
(2012)
J. Physiol.
, vol.590
, pp. 2151-2165
-
-
Wang, Q.1
McPherron, A.C.2
-
96
-
-
0035957323
-
Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication
-
Wang Y, Michikawa Y, Mallidis C, Bai Y, Woodhouse L, Yarasheski KE, Miller CA, Askanas V, Engel WK, Bhasin S, Attardi G (2001) Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication. Proc. Natl Acad. Sci. USA 98, 4022-4027.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 4022-4027
-
-
Wang, Y.1
Michikawa, Y.2
Mallidis, C.3
Bai, Y.4
Woodhouse, L.5
Yarasheski, K.E.6
Miller, C.A.7
Askanas, V.8
Engel, W.K.9
Bhasin, S.10
Attardi, G.11
-
97
-
-
17044408768
-
JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
-
Wang MC, Bohmann D, Jasper H (2005) JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 121, 115-125.
-
(2005)
Cell
, vol.121
, pp. 115-125
-
-
Wang, M.C.1
Bohmann, D.2
Jasper, H.3
-
98
-
-
0018938819
-
Differential decrease in protein synthesis by microsomes from aging Drosophila melanogaster
-
Webster GC, Beachell VT, Webster SL (1980) Differential decrease in protein synthesis by microsomes from aging Drosophila melanogaster. Exp. Gerontol. 15, 495-497.
-
(1980)
Exp. Gerontol.
, vol.15
, pp. 495-497
-
-
Webster, G.C.1
Beachell, V.T.2
Webster, S.L.3
-
99
-
-
73949099327
-
Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging
-
Wenz T, Rossi SG, Rotundo RL, Spiegelman BM, Moraes CT (2009) Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging. Proc. Natl Acad. Sci. USA 106, 20405-20410.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 20405-20410
-
-
Wenz, T.1
Rossi, S.G.2
Rotundo, R.L.3
Spiegelman, B.M.4
Moraes, C.T.5
-
100
-
-
0037462964
-
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength
-
Whittemore LA, Song K, Li X, Aghajanian J, Davies M, Girgenrath S, Hill JJ, Jalenak M, Kelley P, Knight A, Maylor R, O'Hara D, Pearson A, Quazi A, Ryerson S, Tan XY, Tomkinson KN, Veldman GM, Widom A, Wright JF, Wudyka S, Zhao L, Wolfman NM (2003) Inhibition of myostatin in adult mice increases skeletal muscle mass and strength. Biochem. Biophys. Res. Commun. 300, 965-971.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.300
, pp. 965-971
-
-
Whittemore, L.A.1
Song, K.2
Li, X.3
Aghajanian, J.4
Davies, M.5
Girgenrath, S.6
Hill, J.J.7
Jalenak, M.8
Kelley, P.9
Knight, A.10
Maylor, R.11
O'Hara, D.12
Pearson, A.13
Quazi, A.14
Ryerson, S.15
Tan, X.Y.16
Tomkinson, K.N.17
Veldman, G.M.18
Widom, A.19
Wright, J.F.20
Wudyka, S.21
Zhao, L.22
Wolfman, N.M.23
more..
-
101
-
-
19944431011
-
Cardiovascular risk factors emerge after artificial selection for low aerobic capacity
-
Wisloff U, Najjar SM, Ellingsen O, Haram PM, Swoap S, Al-Share Q, Fernstrom M, Rezaei K, Lee SJ, Koch LG, Britton SL (2005) Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science 307, 418-420.
-
(2005)
Science
, vol.307
, pp. 418-420
-
-
Wisloff, U.1
Najjar, S.M.2
Ellingsen, O.3
Haram, P.M.4
Swoap, S.5
Al-Share, Q.6
Fernstrom, M.7
Rezaei, K.8
Lee, S.J.9
Koch, L.G.10
Britton, S.L.11
-
102
-
-
84864287504
-
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
-
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, Khandekar M, Virtanen KA, Nuutila P, Schaart G, Huang K, Tu H, van Marken Lichtenbelt WD, Hoeks J, Enerbäck S, Schrauwen P, Spiegelman BM (2012) Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150, 366-376.
-
(2012)
Cell
, vol.150
, pp. 366-376
-
-
Wu, J.1
Boström, P.2
Sparks, L.M.3
Ye, L.4
Choi, J.H.5
Giang, A.H.6
Khandekar, M.7
Virtanen, K.A.8
Nuutila, P.9
Schaart, G.10
Huang, K.11
Tu, H.12
van Marken Lichtenbelt, W.D.13
Hoeks, J.14
Enerbäck, S.15
Schrauwen, P.16
Spiegelman, B.M.17
-
103
-
-
0034565122
-
Prevention of flight activity prolongs the life span of the housefly, Musca domestica, and attenuates the age-associated oxidative damage to specific mitochondrial proteins
-
Yan LJ, Sohal RS (2000) Prevention of flight activity prolongs the life span of the housefly, Musca domestica, and attenuates the age-associated oxidative damage to specific mitochondrial proteins. Free Radic. Biol. Med. 29, 1143-1150.
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 1143-1150
-
-
Yan, L.J.1
Sohal, R.S.2
-
104
-
-
35449004069
-
Foxo1 represses expression of musclin, a skeletal muscle-derived secretory factor
-
Yasui A, Nishizawa H, Okuno Y, Morita K, Kobayashi H, Kawai K, Matsuda M, Kishida K, Kihara S, Kamei Y, Ogawa Y, Funahashi T, Shimomura I (2007) Foxo1 represses expression of musclin, a skeletal muscle-derived secretory factor. Biochem. Biophys. Res. Commun. 364, 358-365.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.364
, pp. 358-365
-
-
Yasui, A.1
Nishizawa, H.2
Okuno, Y.3
Morita, K.4
Kobayashi, H.5
Kawai, K.6
Matsuda, M.7
Kishida, K.8
Kihara, S.9
Kamei, Y.10
Ogawa, Y.11
Funahashi, T.12
Shimomura, I.13
-
105
-
-
0042471736
-
Accumulation of deleted mitochondrial DNA in aging Drosophila melanogaster
-
Yui R, Ohno Y, Matsuura ET (2003) Accumulation of deleted mitochondrial DNA in aging Drosophila melanogaster. Genes Genet. Syst. 78, 245-251.
-
(2003)
Genes Genet. Syst.
, vol.78
, pp. 245-251
-
-
Yui, R.1
Ohno, Y.2
Matsuura, E.T.3
-
106
-
-
78149270788
-
Insulin-like 6 is induced by muscle injury and functions as a regenerative factor
-
Zeng L, Akasaki Y, Sato K, Ouchi N, Izumiya Y, Walsh K (2010) Insulin-like 6 is induced by muscle injury and functions as a regenerative factor. J. Biol. Chem. 285, 36060-36069.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 36060-36069
-
-
Zeng, L.1
Akasaki, Y.2
Sato, K.3
Ouchi, N.4
Izumiya, Y.5
Walsh, K.6
-
107
-
-
24744456694
-
Differential patterns of apoptosis in response to aging in Drosophila
-
Zheng J, Edelman SW, Tharmarajah G, Walker DW, Pletcher SD, Seroude L (2005) Differential patterns of apoptosis in response to aging in Drosophila. Proc. Natl. Acad. Sci U S A 102, 12083-12088.
-
(2005)
Proc. Natl. Acad. Sci U S A
, vol.102
, pp. 12083-12088
-
-
Zheng, J.1
Edelman, S.W.2
Tharmarajah, G.3
Walker, D.W.4
Pletcher, S.D.5
Seroude, L.6
-
108
-
-
77955642517
-
Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival
-
Zhou X, Wang JL, Lu J, Song Y, Kwak KS, Jiao Q, Rosenfeld R, Chen Q, Boone T, Simonet WS, Lacey DL, Goldberg AL, Han HQ (2010) Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival. Cell 142, 531-543.
-
(2010)
Cell
, vol.142
, pp. 531-543
-
-
Zhou, X.1
Wang, J.L.2
Lu, J.3
Song, Y.4
Kwak, K.S.5
Jiao, Q.6
Rosenfeld, R.7
Chen, Q.8
Boone, T.9
Simonet, W.S.10
Lacey, D.L.11
Goldberg, A.L.12
Han, H.Q.13
-
109
-
-
71849089034
-
Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency
-
Zigmond MJ, Cameron JL, Leak RK, Mirnics K, Russell VA, Smeyne RJ, Smith AD (2009) Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency. Parkinsonism Relat. Disord. 15, S42-S45.
-
(2009)
Parkinsonism Relat. Disord.
, vol.15
-
-
Zigmond, M.J.1
Cameron, J.L.2
Leak, R.K.3
Mirnics, K.4
Russell, V.A.5
Smeyne, R.J.6
Smith, A.D.7
-
110
-
-
0037165983
-
Induction of cachexia in mice by systemically administered myostatin
-
Zimmers TA, Davies MV, Koniaris LG, Haynes P, Esquela AF, Tomkinson KN, McPherron AC, Wolfman NM, Lee SJ (2002) Induction of cachexia in mice by systemically administered myostatin. Science 296, 1486-1488.
-
(2002)
Science
, vol.296
, pp. 1486-1488
-
-
Zimmers, T.A.1
Davies, M.V.2
Koniaris, L.G.3
Haynes, P.4
Esquela, A.F.5
Tomkinson, K.N.6
McPherron, A.C.7
Wolfman, N.M.8
Lee, S.J.9
|