Age-related modifications in circulating IL-15 levels in humans

Mediators of Inflammation

Volumn 2005, Issue 4, 2005, Pages 245-247

  Gangemi, Sebastiano ^a   Basile, Giorgio ^a   Monti, Daniela ^b   Merendino, Rosaria Alba ^a   Di Pasquale, Giuseppe ^a   Bisignano, Ursula ^a   Nicita Mauro, Vittorio ^a   Franceschi, Claudio ^c  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15;

AGE; AGED; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CIRCULATION; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FEMALE; HUMAN; INFECTION; INFLAMMATION; MALE; MEMORY CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN MODIFICATION; SENESCENCE; STATISTICAL ANALYSIS;

ADULT; AGED; AGING; CELL PROLIFERATION; FEMALE; HUMANS; IMMUNOLOGIC MEMORY; INFLAMMATION; INTERLEUKIN-15; MALE; MIDDLE AGED; T-LYMPHOCYTES;

EID: 25644432665     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/MI.2005.245     Document Type: Article

References (5)

1. De Martinis M, Franceschi C, Monti D, Ginaldi L. Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett. 2005;579(10):2035-2039.
2. Fehniger TA, Caligiuri MA. Interleukin 15: biology and relevance to human disease. Blood. 2001;97(1):14-32.
3. Tortorella C, Pisconti A, Piazzolla G, Antonaci S. APC-dependent impairment of T cell proliferation in aging: role of CD28- and IL-12/IL-15-mediated signaling. Mech Ageing Dev. 2002;123(10):1389-1402.
4. Gangemi S, Basile G, Merendino RA, et al. Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity? Exp Gerontol. 2003;38(6):669-672.
5. + T cells is dispensable for T cell memory. Proc Natl Acad Sci U S A. 2003;100(8):4724-4729.