Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Guo, Tingqing ^a   Jou, William ^a   Chanturiya, Tatyana ^a   Portas, Jennifer ^a   Gavrilova, Oksana ^a   McPherron, Alexandra C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR 2B; GLUCOSE; INSULIN; MYOSTATIN; UNCLASSIFIED DRUG; PROTEIN KINASE B;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CALORIMETRY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE RESISTANCE; DRUG TARGETING; GENE DELETION; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HYPERINSULINEMIA; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LEAN BODY WEIGHT; LIPID DIET; LIPID OXIDATION; MALE; MOUSE; MUSCLE MASS; NONHUMAN; OBESITY; PROTEIN EXPRESSION; RISK REDUCTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSGENIC MOUSE; WEIGHT GAIN; ANIMAL; C57BL MOUSE; DIET; DRUG ANTAGONISM; FAT INTAKE; GLUCOSE CLAMP TECHNIQUE; HISTOLOGY; HUMAN; INSULIN RESISTANCE; LIPID METABOLISM; METABOLISM; MOUSE MUTANT; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

MUS; MUS MUSCULUS;

ADIPOSE TISSUE; ANIMALS; DIET; DIETARY FATS; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; MYOSTATIN; OXIDATION-REDUCTION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 63349107479     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004937     Document Type: Article

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