The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker

European Journal of Medicinal Chemistry

Volumn 70, Issue , 2013, Pages 703-722

  Głowacka, Iwona E ^a   Balzarini, Jan ^b   Wróblewski, Andrzej E ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

1,2,3 Triazoles; Acyclonucleotides; Antiviral; Aziodophosphonates; Cytostatic; Synthesis

Indexed keywords

ACYCLIC NUCLEOSIDE; ANTIVIRUS AGENT; CYTOSTATIC AGENT; NUCLEOTIDE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOSTASIS; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG SCREENING; DRUG SYNTHESIS; HELA CELL; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; LEUKEMIA; MICROWAVE IRRADIATION; NONHUMAN; T LYMPHOCYTE; UTERINE CERVIX CARCINOMA;

1,2,3-TRIAZOLES; ACYCLONUCLEOTIDES; ANTIVIRAL; AZIODOPHOSPHONATES; CYTOSTATIC; SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOSTATIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HUMANS; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES;

EID: 84887184290     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.10.057     Document Type: Article

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