Synthesis and cytotoxicity evaluation of novel 1,4-disubstituted 1,2,3-triazoles via CuI catalysed 1,3-dipolar cycloaddition

European Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2010, Pages 5044-5050

  Vantikommu, Jyothi ^a   Palle, Sadanandam ^b   Surendra Reddy, Punganuru ^b,c   Ramanatham, Vinodkumar ^b   Khagga, Mukkanti ^b   Pallapothula, Venkateswara Rao ^a  

^a OSMANIA UNIVERSITY   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^c INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Keto 1,2,3 triazoles; 1,3 Dipolar cycloaddition; Copper iodide; Cytotoxicity; Terminal alkynes; Tosyloxyketones

Indexed keywords

1 (4 BROMO PHENYL) 2 (4 PHENYL[1,2,3]TRIAZOL 1 YL) ETHANONE; 1 (4 CHLORO-PHENYL) 2 (4 PHENYL[1,2,3]TRIAZOL 1 YL) ETHANONE; 1 PHENYL 2 (4 PHENYL[1,2,3]TRIAZOL 1 YL) BUTAN 1 ONE; 1 PHENYL 2 (4 PHENYL[1,2,3]TRIAZOL 1 YL) ETHANONE; 1 PHENYL 2 (4 PHENYL[1,2,3]TRIAZOL 1 YL) PROPAN 1 ONE; 1 PHENYL 2 (4 PYRIDIN 2 YL [1,2,3]TRIAZOL 1 YL) ETHANONE; 1 PHENYL 2 (4 THIOPHEN 3 YL [1,2,3]TRIAZOL 1 YL) ETHANONE; 1 PHENYL 2 [4 (2,4,5 TRIMETHYL PHENYL) [1,2,3]TRIAZOL 1 YL] ETHANONE; 1,2,3 TRIAZOLE DERIVATIVE; 2 (4 HEXYL [1,2,3]TRIAZOL 1 YL) 1 PHENYL ETHANONE; 2 (4 HYDROXYMETHYL [1,2,3]TRIAZOL 1 YL) 1 PHENYL ETHANONE; 2 (4 PHENYL[1,2,3]TRIAZOL 1 YL) 1 4 TOLYL ETHANONE; 2 [4 (3 METHOXY PHENYL) [1,2,3]TRIAZOL 1 YL] 1 PHENYL ETHANONE; 2 [4 (4 METHOXY PHENYL) [1,2,3]TRIAZOL 1 YL] 1 PHENYL ETHANONE; 2 [4 (4 PENTYL PHENYL) [1,2,3]TRIAZOL 1 YL] 1 PHENYL ETHANONE; 2 [4 (6 METHOXY NAPHTHALEN 2 YL) [1,2,3]TRIAZOL 1 YL] 1-PHENYL ETHANONE; ACETONE; ALKYNE; ANTINEOPLASTIC AGENT; COLCHICINE; COPPER; PODOPHYLLOTOXIN; UNCLASSIFIED DRUG; WATER;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; COLON CANCER; CONTROLLED STUDY; CYCLOADDITION; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; LUNG CANCER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ROOM TEMPERATURE; UTERINE CERVIX CANCER;

CATALYSIS; CELL LINE, TUMOR; COPPER; CYCLIZATION; DRUG EVALUATION, PRECLINICAL; HUMANS; TRIAZOLES;

EID: 77957825923     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.08.012     Document Type: Article

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