Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues

BMC Genomics

Volumn 14, Issue 1, 2013, Pages

  Schupp, Michael ^c   Chen, Fang ^d   Briggs, Erika R ^d   Rao, Shilpa ^f   Pelzmann, Helmut J ^a,b   Pessentheiner, Ariane R ^a,b   Bogner Strauss, Juliane G ^a,b   Lazar, Mitchell A ^d   Baldwin, Don ^e   Prokesch, Andreas ^a,b  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e Pathonomics LLC   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adipose tissue; Ddit4; Fasting; Lipolysis; Nutrient deprivation; p53 signaling; Starvation

Indexed keywords

PROTEIN DDIT4; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTOME; UNCLASSIFIED DRUG; DDIT4 PROTEIN, MOUSE;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIET RESTRICTION; EPIDIDYMIS; GENE EXPRESSION; GLUCONEOGENESIS; IN VIVO STUDY; KETOGENESIS; LIPOLYSIS; LIVER METABOLISM; MALE; METABOLITE; MOUSE; MUSCLE METABOLISM; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TISSUE METABOLISM; TRANSCRIPTION REGULATION; UNINDEXED SEQUENCE; WEIGHT CHANGE; WHITE ADIPOSE TISSUE; ANIMAL; C3H MOUSE; C57BL MOUSE; CELL LINE; DNA MICROARRAY; FOOD DEPRIVATION; GENE EXPRESSION PROFILING; GENETICS; LIPOGENESIS; LIVER; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGICAL STRESS; TRANSCRIPTION INITIATION; UPREGULATION;

MUS;

ADIPOSE TISSUE, WHITE; ANIMALS; CELL LINE; FOOD DEPRIVATION; GENE EXPRESSION PROFILING; GLUCONEOGENESIS; LIPOGENESIS; LIPOLYSIS; LIVER; MALE; MICE, INBRED C3H; MICE, INBRED C57BL; MOLECULAR SEQUENCE ANNOTATION; MUSCLE, SKELETAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84887056665     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-14-758     Document Type: Article

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