Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues

Journal of Lipid Research

Volumn 46, Issue 4, 2005, Pages 697-705

  Gosmain, Yvan ^a   Dif, Nicolas ^a   Berbe, Vanessa ^a   Loizon, Emmanuelle ^a   Rieusset, Jennifer ^a   Vidal, Hubert ^a   Lefai, Etienne ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Chromatin immunoprecipitation; Fatty acid synthase; Gene expression; Glucose metabolism; Hexokinase 2; Lipogenesis; Nutritional regulation; Quantitative reverse transcriptase polymerase chain reaction; Sterol regulatory element binding protein 1

Indexed keywords

FAS ANTIGEN; HEXOKINASE; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; CCAAT ENHANCER BINDING PROTEIN; DNA BINDING PROTEIN; SREBF1 PROTEIN, RAT; TRANSCRIPTION FACTOR;

ADIPOSE TISSUE; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DIET RESTRICTION; ENZYME REGULATION; GLUCOSE METABOLISM; HOMEOSTASIS; IN VIVO STUDY; LIPID METABOLISM; LIPOGENESIS; MALE; NONHUMAN; NUTRITION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; RAT; REFEEDING; SKELETAL MUSCLE; ANIMAL; ANIMAL FOOD; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LIVER; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADIPOSE TISSUE; ANIMAL FEED; ANIMALS; ANTIGENS, CD95; CCAAT-ENHANCER-BINDING PROTEINS; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; FASTING; GENE EXPRESSION REGULATION; HEXOKINASE; LIVER; MALE; MUSCLE, SKELETAL; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 19344361859     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M400261-JLR200     Document Type: Article

References (50)

1. Foufelle, F., and P. Ferre. 2002. New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1. Biochem. J. 366: 377-391.
2. Osborne, T. F. 2000. Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J. Biol. Chem. 275: 32379-32382.
3. Brown, M. S., and J. L. Goldstein. 1997. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membranebound transcription factor. Cell. 89: 331-340.
4. Briggs, M. R., C. Yokoyama, X. Wang, M. S. Brown, and J. L. Goldstein. 1993. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence. J. Biol. Chem. 268: 14490-14496.
5. Hua, X., C. Yokoyama, J. Wu, M. R. Briggs, M. S. Brown, J. L. Goldstein, and X. Wang. 1993. SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. Proc. Natl. Acad. Sci. USA. 90: 11603-11607.
6. Sakai, J., E. A. Duncan, R. B. Rawson, X. Hua, M. S. Brown, and J. L. Goldstein. 1996. Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment. Cell. 85: 1037-1046.
7. Wang, X., M. R. Briggs, X. Hua, C. Yokoyama, J. L. Goldstein, and M. S. Brown. 1993. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization. J. Biol. Chem. 268: 14497-14504.
8. Becard, D., I. Hainault, D. Azzout-Marniche, L. Bertry-Coussot, P. Ferre, and F. Foufelle. 2001. Adenovirus-mediated overexpression of sterol regulatory element hinding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice. Diabetes. 50: 2425-2430.
9. Foretz, M., C. Guichard, P. Ferre, and F. Foufelle. 1999. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc. Natl, Acad. Sci. USA. 96: 12737-12742.
10. Gosmain, Y, E. Lefai, S. Ryser, M. Roques, and H. Vidal. 2004. Sterol regulatory element-binding protein-1 mediates the effect of insulin on hexokinase 11 gene expression in human muscle cells. Diabetes. 53: 321-329.
11. Guillet-Deniau, I., V. Mieulet, S. Le Lay, Y. Achouri, D. Carre, J. Girard, F. Foufelle, and P. Ferre. 2002. Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression. Diabetes. 51: 1722-1728.
12. Kim, J. B., P. Sarraf, M. Wright, K. M. Yao, E. Mueller, G. Solanes, B. B. Lowell, and B. M. Spiegelman. 1998. Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J. Clin. Invest. 101: 1-9.
13. Azzout-Marniche, D., D. Becard, C. Guichard, M. Foretz, P. Ferre, and F. Foufelle. 2000. Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. Biochem. J. 350: 389-393.
14. Ducluzeau, P. H., N. Perretti, M. Laville, F. Andreelli, N. Vega, J. P. Riou, and H. Vidal. 2001. Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes. 50: 1134-1142.
15. Shimomura, I, Y. Bashmakov, S. Ikemoto, J. D. Horton, M. S. Brown, and J. L. Goldstein. 1999. Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes. Proc. Natl. Acad. Sci. USA. 96: 13656-13661.
16. Fleischmann, M., and P. B. Iynedjian. 2000. Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt. Biochem. J. 349: 13-17.
17. Horton, J. D., Y Bashmakov, I. Shimomura, and H. Shimano. 1998. Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc. Natl. Acad. Sci. USA. 95: 5987-5992.
18. Ribot, J., M. Rantala, Y A. Kesaniemi, A. Palou, and M. J. Savolainen. 2001. Weight loss reduces expression of SREBP1c/ADD1 and PPARgamma2 in adipose tissue of obese women. Pflugers Arch. 441: 498-505.
19. Andreolas, C., G. da Silva Xavier, F. Diraison, C. Zhao, A. Varadi, F. Lopez-Casillas, P. Ferre, F. Foufelle, and G. A. Rutter. 2002. Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells. Diabetes. 51: 2536-2545.
20. Kajita, K., T. Ishizuka, T. Mune, A. Miura, M. Ishizawa, Y. Kanoh, Y Kawai, Y Natsume, and K. Yasuda. 2003. Dehydroepiandrosterone down-regulates the expression of peroxisome proliferator-activated receptor gamma in adipocytes. Endocrinology. 144: 253-259.
21. Latasa, M. J., M. J. Griffin, Y S. Moon, C. Kang, and H. S. Sul. 2003. Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals. Mol. Cell. Biol. 23: 5896-5907.
22. Shimomura, I., H. Shimano, J. D. Horton, J. L. Goldstein, and M. S. Brown. 1997. Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J. Clin. Invest. 99: 838-845.
23. Bizeau, M. E., P. S. MacLean, G. C. Johnson, and Y Wei. 2003. Skeletal muscle sterol regulatory element binding protein-1c decreases with food deprivation and increases with feeding in rats. J. Nutr. 133: 1787-1792.
24. Commerford, S. R., L. Peng, J. J. Dube, and R. M. O'Doherty. 2004. In vivo regulation of SREBP-1c in skeletal muscle: effects of nutritional status, glucose, insulin and leptin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 287: 218-227.
25. Auboeuf, D., and H. Vidal. 1997. The use of the reverse transcription-competitive polymerase chain reaction to investigate the in vivo regulation of gene expression in small tissue samples. Anal. Biochem. 245: 141-148.
26. Mingrone, G., G. Rosa, A. V. Greco, M. Manco, N. Vega, G. Nanni, M. Castagneto, and H. Vidal. 2003. Intramyocitic lipid accumulation and SREBP-1c expression are related to insulin resistance and cardiovascular risk in morbid obesity. Atherosclerosis. 170: 155-161.
27. Orlando, V, H. Strutt, and R. Paro. 1997. Analysis of chromatin structure by in vivo formaldehyde cross-linking. Methods. 11: 205-214.
28. Duong, D. T., M. E. Waltner-Law, R. Sears, L. Sealy, and D. K. Granner. 2002. Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter. J. Biol. Chem. 277: 32234-32242.
29. Foretz, M., C. Pacot, I. Dugail, P. Lemarchand, C. Guichard, X. Le Liepvre, C. Berthelier-Lubrano, B. Spiegelman, J. B. Kim, P. Ferre, and F. Foufelle. 1999. ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose. Mol. Cell. Biol. 19: 3760-3768.
30. Kim, J. B., and B. M. Spiegelman. 1996. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev. 10: 1096-1107.
31. Le Lay, S., I. Lefrere, C. Trautwein, I. Dugail, and S. Krief. 2002. Insulin and sterol-regulatory element-binding protein-1c (SREBP-1c) regulation of gene expression in 3T3-L1 adipocytes. Identification of CCAAT/enhancer- binding protein beta as an SREBP-1c target. J. Biol. Chem. 277: 35625-35634.
32. Koo, S. H., A. K. Dutcher, and H. C. Towle. 2001. Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver. J. Biol. Chem. 276: 9437-9445.
33. Sone, H., H. Shimano, Y. Sakakura, N. Inoue, M. Amemiya-Kudo, N. Yahagi, M. Osawa, H. Suzuki, T. Yokoo, A. Takahashi, K. Iida, H. Toyoshima, A. Iwama, and N. Yamada. 2002. Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status. Am. J. Physiol. Endomnol. Metab. 282: E222-E230.
34. Oh, S. Y., S. K. Park, J. W. Kim, Y. H. Ahn, S. W. Park, and K. S. Kim. 2003. Acetyl-CoA carboxylase beta gene is regulated by sterol regulatory element-binding protein-1 in liver. J. Biol. Chem. 278: 28410-28417.
35. Jackson, S. M., J. Ericsson, R. Mantovani, and P. A. Edwards. 1998. Synergistic activation of transcription by nuclear factor Y and sterol regulatory element binding protein. J. Lipid Res. 39: 767-776.
36. Sanchez, H. B., L. Yieh, and T. F. Osborne. 1995. Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene. J. Biol. Chem. 270: 1161-1169.
37. Magana, M. M., S. H. Koo, H. C. Towle, and T. F. Osborne. 2000. Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. J. Biol. Chem. 275: 4726-4733.
38. Lakshmanan, M. R., C. M. Nepokroeff, and J. W. Porter. 1972. Control of the synthesis of fatty-acid synthetase in rat liver by insulin, glucagon, and adenosine 3′:5′ cyclic monophosphate. Proc. Natl. Acad. Sci. USA. 69: 3516-3519.
39. Wakil, S. J., J. K. Stoops, and V. C. Joshi. 1983. Fatty acid synthesis and its regulation. Annu. Rev. Biochem. 52: 537-579.
40. Postic, C., A. Leturque, F. Rencurel, R. L. Printz, C. Forest, D. K. Granner, and J. Girard. 1993. The effects of hyperinsulinemia and hyperglycemia on GLUT4 and hexokinase II mRNA and protein in rat skeletal muscle and adipose tissue. Diabetes. 42: 922-929.
41. Printz, R. L., S. Koch, L. R. Potter, R. M. O'Doherty, J. J. Tiesinga, S. Moritz, and D. K. Granner. 1993. Hexokinase II mRNA and gene structure, regulation by insulin, and evolution. J. Biol. Chem. 268: 5209-5219.
42. Postic, C., A. Leturque, R. L. Printz, P. Maulard, M. Loizeau, D. K. Granner, and J. Girard. 1994. Development and regulation of glucose transporter and hexokinase expression in rat. Am. J. Physiol. 266: E548-E559.
43. Shimano, H., N. Yahagi, M. Amemiya-Kudo, A. H. Hasty, J. Osuga, Y. Tamura, F. Shionoiri, Y. Iizuka, K. Ohashi, K. Harada, T. Gotoda, S. Ishibashi, and N. Yamada. 1999. Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. J. Biol. Chem. 274: 35832-35839.
44. Bennett, M. K., J. I. Toth, and T. F. Osborne. 2004. Selective association of sterol regulatory element binding protein isoforms with target promoters in vivo. J. Biol. Chem. 279: 40185-40193.
45. Shimano, H., J. D. Horton, I. Shimomura, R. E. Hammer, M. S. Brown, and J. L. Goldstein. 1997. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin. Invest. 99: 846-854.
46. Amemiya-Kudo, M., H. Shimano, T. Yoshikawa, N. Yahagi, A. H. Hasty, H. Okazaki, Y. Tamura, F. Shionoiri, Y. Iizuka, K. Ohashi, J. Osuga, K. Harada, T. Gotoda, R. Sato, S. Kimura, S. Ishibashi, and N. Yamada. 2000. Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene. J. Biol. Chem. 275: 31078-31085.
47. Gagen, L. M., X. Deng, H. G. Wilcox, E. A. Park, R. Raghow, and M. B. Elam. 2004. Insulin activates the rat sterol regulatory element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1, and NF-Y cis-acting elements. Biochem J. 385: 207-216.
48. Kawaguchi, T, M. Takenoshita, T. Kabashima, and K. Uyeda. 2001. Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/ dephosphorylation of the carbohydrate response element binding protein. Proc. Natl. Acad. Sci. USA. 98: 13710-13715.
49. Yamashita, H., M. Takenoshita, M. Sakurai, R. K. Bruick, W. J. Henzel, W. Shillinglaw, D. Arnot, and K. Uyeda. 2001. A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc. Natl. Acad. Sci. USA. 98: 9116-9121.
50. Joseph, S. B., B. A. Laffitte, P. H. Patel, M. A. Watson, K. E. Matsukuma, R. Walczak, J. L. Collins, T. F. Osborne, and P. Tontonoz. 2002. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J. Biol. Chem. 277: 11019-11025.