Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 750, Issue 1-2, 2013, Pages 15-22

  Mermershtain, Inbal ^a   Glover, J N Mark ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

BRCT domains; Double strand break signaling; FHA domains; Phosphorylation signaling; Ubc13; Ubiquitin; UIM

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DOUBLE STRANDED DNA; LYSINE; MRE11 PROTEIN; NIBRIN; OVARIAN TUMOR DOMAIN PROTEIN 1; PHOSPHOPEPTIDE; PHOSPHOSERINE; PHOSPHOTHREONINE; RAD50 PROTEIN; RING FINGER PROTEIN; RING FINGER PROTEIN 168; RING FINGER PROTEIN 4; RING FINGER PROTEIN 8; TUMOR PROTEIN; UBIQUITIN CONJUGATING ENZYME 13; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

BRCA1 C TERMINAL DOMAIN; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME BINDING; ENZYME INHIBITION; FORKHEAD ASSOCIATED DOMAIN; HUMAN; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; UBIQUITIN INTERACTION MOTIF; UBIQUITINATION;

BRCA1 C-TERMINAL DOMAIN; BRCT; BRCT DOMAINS; DOUBLE STRAND BREAK; DOUBLE-STRAND BREAK SIGNALING; DSB; FHA DOMAINS; FHAF; HOMOLOGOUS RECOMBINATION; HR; MRE11-RAD50-NBS1; MRN; ORKHEAD-ASSOCIATED DOMAIN.; OTUB; OTUBAIN OR OVARIAN TUMOR DOMAIN PROTEIN; PHOSPHORYLATION SIGNALING; RADIOSENSITIVITY, IMMUNODEFICIENCY, DYSMORPHIC FEATURES AND LEARNING DIFFICULTIES; RIDDLE SYNDROME; UBC13; UBIQUITIN; UBIQUITIN INTERACTION MOTIF; UIM;

ANIMALS; CELL CYCLE PROTEINS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; HOMOLOGOUS RECOMBINATION; HUMANS; MODELS, MOLECULAR; NUCLEAR PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 84886950182     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2013.07.004     Document Type: Review

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