Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23900-23910

  Campbell, Stephen J ^a   Edwards, Ross A ^a   Leung, Charles C Y ^a   Neculai, Dante ^b   Hodge, Curtis D ^a   Dhe Paganon, Sirano ^b   Glover, J N Mark ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SURFACE; BREAST CANCER; COILED COIL; DNA DAMAGE RESPONSE; DNA DOUBLE STRAND BREAKS; E3 UBIQUITIN LIGASES; HOMOLOGOUS RECOMBINATION; MOLECULAR INSIGHTS; POLYUBIQUITYLATION; RING FINGER; STRUCTURAL BASIS; TERNARY COMPLEX; UBIQUITIN; UBIQUITYLATION;

BIOCHEMISTRY; BIOLOGY;

PROTEINS;

BMI1 PROTEIN; DNA; DOUBLE STRANDED DNA; LYSINE; RING FINGER PROTEIN; UBIQUITIN CONJUGATING ENZYME 13;

ARTICLE; BINDING SITE; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DOWN REGULATION; GENE MUTATION; HOMOLOGOUS RECOMBINATION; HUMAN; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RING FINGER MOTIF; UBIQUITINATION;

AMINO ACID SEQUENCE; BIOCATALYSIS; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; LIGASES; LYSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; ZINC FINGERS;

EID: 84863611076     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.359653     Document Type: Article

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