-
1
-
-
33644658460
-
Oxidative stress and lysosomes: CNS-related consequences and implications for lysosom-al enhancement strategies and induction of autophagy
-
Butler D, Bahr BA. Oxidative stress and lysosomes: CNS-related consequences and implications for lysosom-al enhancement strategies and induction of autophagy. Antioxid Redox Signal. 2006;8:185-196.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 185-196
-
-
Butler, D.1
Bahr, B.A.2
-
2
-
-
8344242220
-
Autophagy in health and disease: A double-edged sword
-
Shintani T, Klionsky DJ. Autophagy in health and disease: a double-edged sword. Science. 2004;306:990-995.
-
(2004)
Science
, vol.306
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
3
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of auto-phagy
-
Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of auto-phagy. Dev Cell. 2004;6:463-477.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
4
-
-
0028254331
-
Regulation of intracellular protein degradation with special reference to lysosomes: Role in cell physiology and pathology
-
Lee HK, Marzella L. Regulation of intracellular protein degradation with special reference to lysosomes: role in cell physiology and pathology. Int Rev Exp Pathol. 1994; 35:39-147.
-
(1994)
Int Rev Exp Pathol
, vol.35
, pp. 39-147
-
-
Lee, H.K.1
Marzella, L.2
-
5
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008;132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
6
-
-
14044277429
-
The molecular machinery of autophagy: Unanswered questions
-
Klionsky DJ. The molecular machinery of autophagy: unanswered questions. J Cell Sci. 2005;118:7-18.
-
(2005)
J Cell Sci
, vol.118
, pp. 7-18
-
-
Klionsky, D.J.1
-
8
-
-
0025363276
-
Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
-
Dunn WA Jr. Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J Cell Biol. 1990;110:1923-1933.
-
(1990)
J Cell Biol
, vol.110
, pp. 1923-1933
-
-
Dunn Jr., W.A.1
-
9
-
-
0025294506
-
Peptide sequences that target cytosolic proteins for lysosomal proteolysis
-
Dice JF. Peptide sequences that target cytosolic proteins for lysosomal proteolysis. Trends Biochem Sci. 1990;15: 305-309.
-
(1990)
Trends Biochem Sci
, vol.15
, pp. 305-309
-
-
Dice, J.F.1
-
10
-
-
4344673498
-
Mechanisms of chaperone-mediated autophagy
-
Majeski AE, Dice JF. Mechanisms of chaperone-mediated autophagy. Int J Biochem Cell Biol. 2004;36:2435-2444.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2435-2444
-
-
Majeski, A.E.1
Dice, J.F.2
-
11
-
-
0029837453
-
A receptor for the selective uptake and degradation of proteins by lysosomes
-
Cuervo AM, Dice JF. A receptor for the selective uptake and degradation of proteins by lysosomes. Science. 1996;273:501-503.
-
(1996)
Science
, vol.273
, pp. 501-503
-
-
Cuervo, A.M.1
Dice, J.F.2
-
12
-
-
51349130544
-
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
-
Bandyopadhyay U, Kaushik S, Varticovski L, et al. The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane. Mol Cell Biol. 2008;28:5747-5763.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5747-5763
-
-
Bandyopadhyay, U.1
Kaushik, S.2
Varticovski, L.3
-
13
-
-
33845298622
-
Pexophagy: Auto-phagic degradation of peroxisomes
-
Sakai Y, Oku M, van der Klei IJ, et al. Pexophagy: auto-phagic degradation of peroxisomes. Biochim Biophys Acta. 2006;1763:1767-1775.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 1767-1775
-
-
Sakai, Y.1
Oku, M.2
van der Klei, I.J.3
-
15
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T, Hall MN. TOR, a central controller of cell growth. Cell. 2000;103:253-262.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
16
-
-
0037329201
-
Chemical ge-netic analysis of Apg1 reveals a non-kinase role in the induction of autophagy
-
Abeliovich H, Zhang C, Klionsky DJ, et al. Chemical ge-netic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. Mol Biol Cell. 2003;14:477-490.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 477-490
-
-
Abeliovich, H.1
Zhang, C.2
Klionsky, D.J.3
-
17
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation and antioxidant de-fenses during aging and in response to food restriction in the mouse
-
Sohal RS, Ku HH, Agarwal S, et al. Oxidative damage, mitochondrial oxidant generation and antioxidant de-fenses during aging and in response to food restriction in the mouse. Mech Ageing Dev. 1994;74:121-133.
-
(1994)
Mech Ageing Dev
, vol.74
, pp. 121-133
-
-
Sohal, R.S.1
Ku, H.H.2
Agarwal, S.3
-
18
-
-
47749142489
-
Clearing the brain's cobwebs: The role of autophagy in neuroprotection
-
Bossy B, Perkins G, Bossy-Wetzel E. Clearing the brain's cobwebs: the role of autophagy in neuroprotection. Curr Neuropharmacol. 2008;6:97-101.
-
(2008)
Curr Neuropharmacol
, vol.6
, pp. 97-101
-
-
Bossy, B.1
Perkins, G.2
Bossy-Wetzel, E.3
-
19
-
-
51049118332
-
The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. "Protein modifi-cations: Beyond the usual suspects review series
-
Geng J, Klionsky DJ. The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. "Protein modifi-cations: beyond the usual suspects review series. EMBO Rep. 2008;9:859-864.
-
(2008)
EMBO Rep
, vol.9
, pp. 859-864
-
-
Geng, J.1
Klionsky, D.J.2
-
20
-
-
0034707036
-
A ubiquitin-like sys-tem mediates protein lipidation
-
Ichimura Y, Kirisako T, Takao T, et al. A ubiquitin-like sys-tem mediates protein lipidation. Nature. 2000;408:488-492.
-
(2000)
Nature
, vol.408
, pp. 488-492
-
-
Ichimura, Y.1
Kirisako, T.2
Takao, T.3
-
21
-
-
77954237882
-
Network organ-ization of the human autophagy system
-
Behrends C, Sowa ME, Harper JW, et al. Network organ-ization of the human autophagy system. Nature. 2010;466:68-76.
-
(2010)
Nature
, vol.466
, pp. 68-76
-
-
Behrends, C.1
Sowa, M.E.2
Harper, J.W.3
-
22
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
Maiuri MC, Zalckvar E, Kimchi A, et al. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol. 2007;8:741-752.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
-
23
-
-
0034948738
-
The autophagosomal-lysosomal compartment in programmed cell death
-
Bursch W. The autophagosomal-lysosomal compartment in programmed cell death. Cell Death Differ. 2001;8:569-581.
-
(2001)
Cell Death Differ
, vol.8
, pp. 569-581
-
-
Bursch, W.1
-
24
-
-
7744235672
-
Death by design: Apoptosis, necrosis and autophagy
-
Edinger AL, Thompson CB. Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol. 2004;16: 663-669.
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 663-669
-
-
Edinger, A.L.1
Thompson, C.B.2
-
25
-
-
23844483152
-
The apop-tosis/autophagy paradox: Autophagic vacuolization before apoptotic death
-
González-Polo RA, Boya P, Pauleau AL, et al. The apop-tosis/autophagy paradox: autophagic vacuolization before apoptotic death. J Cell Sci. 2005;118:3091-3102.
-
(2005)
J Cell Sci
, vol.118
, pp. 3091-3102
-
-
González-Polo, R.A.1
Boya, P.2
Pauleau, A.L.3
-
26
-
-
42749095390
-
Recycle or die: The role of autophagy in cardioprotection
-
Gustafsson AB, Gottlieb RA. Recycle or die: the role of autophagy in cardioprotection. J Mol Cell Cardiol. 2008;44:654-661.
-
(2008)
J Mol Cell Cardiol
, vol.44
, pp. 654-661
-
-
Gustafsson, A.B.1
Gottlieb, R.A.2
-
27
-
-
20444363122
-
The coordinate regula-tion of the p53 and mTOR pathways in cells
-
Feng Z, Zhang H, Levine AJ, et al. The coordinate regula-tion of the p53 and mTOR pathways in cells. Proc Natl Acad Sci U S A. 2005;102:8204-8209.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8204-8209
-
-
Feng, Z.1
Zhang, H.2
Levine, A.J.3
-
28
-
-
25144457455
-
Bcl-2 antiapoptotic pro-teins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic pro-teins inhibit Beclin 1-dependent autophagy. Cell. 2005;122: 927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
29
-
-
77950252174
-
Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
-
Djavaheri-Mergny M, Maiuri MC, Kroemer G. Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene. 2010;29:1717-1719.
-
(2010)
Oncogene
, vol.29
, pp. 1717-1719
-
-
Djavaheri-Mergny, M.1
Maiuri, M.C.2
Kroemer, G.3
-
30
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: Dissection of auto-phagic cell death into vacuole formationand cell death
-
Pyo JO, Jang MH, Kwon YK, et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of auto-phagic cell death into vacuole formationand cell death. J Biol Chem. 2005;280:20722-20729.
-
(2005)
J Biol Chem
, vol.280
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
-
32
-
-
73849114180
-
Enhancement of auto-phagic flux after neonatal cerebral hypoxia-ischemia and its region-specific relationship to apoptotic mechanisms
-
Ginet V, Puyal J, Clarke PG, et al. Enhancement of auto-phagic flux after neonatal cerebral hypoxia-ischemia and its region-specific relationship to apoptotic mechanisms. Am J Pathol. 2009;175:1962-1974.
-
(2009)
Am J Pathol
, vol.175
, pp. 1962-1974
-
-
Ginet, V.1
Puyal, J.2
Clarke, P.G.3
-
34
-
-
1542283812
-
In vivo anal-ysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima N, Yamamoto A, Matsui M, et al. In vivo anal-ysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell. 2004;15:1101-1111.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
-
35
-
-
0034304390
-
The endosomal- lyso-somal system of neurons in Alzheimer's disease pathogene-sis: A review
-
Nixon RA, Cataldo AM, Mathews PM. The endosomal- lyso-somal system of neurons in Alzheimer's disease pathogene-sis: a review. Neurochem Res. 2000;25:1161-1172.
-
(2000)
Neurochem Res
, vol.25
, pp. 1161-1172
-
-
Nixon, R.A.1
Cataldo, A.M.2
Mathews, P.M.3
-
36
-
-
84866155363
-
Neuronal autophagy: A housekeeper or a fighter in neuronal cell survival?
-
Lee JA. Neuronal autophagy: a housekeeper or a fighter in neuronal cell survival? Exp Neurobiol. 2012;21:1-8.
-
(2012)
Exp Neurobiol
, vol.21
, pp. 1-8
-
-
Lee, J.A.1
-
37
-
-
84886697820
-
mTOR kinase, a key player in the regulation of glial functions: Relevance for the therapy of multiple sclerosis
-
in press
-
Dello Russo C, Lisi L, Feinstein DL, et al. mTOR kinase, a key player in the regulation of glial functions: Relevance for the therapy of multiple sclerosis. Glia. in press.
-
Glia
-
-
Dello, R.C.1
Lisi, L.2
Feinstein, D.L.3
-
38
-
-
9644254067
-
Can autophagy protect against neurodegeneration caused by aggregate-prone proteins?
-
Ravikumar B, Rubinsztein DC. Can autophagy protect against neurodegeneration caused by aggregate-prone proteins? Neuroreport. 2004;15:2443-2445.
-
(2004)
Neuroreport
, vol.15
, pp. 2443-2445
-
-
Ravikumar, B.1
Rubinsztein, D.C.2
-
39
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M, Waguri S, Chiba T, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature. 2006;441:880-884.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
-
40
-
-
69949175897
-
Review: Autophagy in neurodegeneration: Fire-fighter and/or incendiarist?
-
Rami A. Review: autophagy in neurodegeneration: fire-fighter and/or incendiarist? Neuropathol Appl Neurobiol. 2009;35:449-461.
-
(2009)
Neuropathol Appl Neurobiol
, vol.35
, pp. 449-461
-
-
Rami, A.1
-
41
-
-
38549129613
-
The potential for beta-structure in the repeat domain of tau protein de-termines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
-
Mocanu MM, Nissen A, Eckermann K, et al. The potential for beta-structure in the repeat domain of tau protein de-termines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy. J Neurosci. 2008;28:737-748.
-
(2008)
J Neurosci
, vol.28
, pp. 737-748
-
-
Mocanu, M.M.1
Nissen, A.2
Eckermann, K.3
-
42
-
-
41149085729
-
Autophag-ic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
-
Hamano T, Gendron TF, Causevic E, et al. Autophag-ic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression. Eur J Neurosci. 2008;27:1119-1130.
-
(2008)
Eur J Neurosci
, vol.27
, pp. 1119-1130
-
-
Hamano, T.1
Gendron, T.F.2
Causevic, E.3
-
43
-
-
2942561028
-
The importance of neuritic plaques and tangles to the development and evolution of AD
-
Tiraboschi P, Hansen LA, Thal LJ, et al. The importance of neuritic plaques and tangles to the development and evolution of AD. Neurology. 2004;62:1984-1989.
-
(2004)
Neurology
, vol.62
, pp. 1984-1989
-
-
Tiraboschi, P.1
Hansen, L.A.2
Thal, L.J.3
-
44
-
-
14844303381
-
Extensive in-volvement of autophagy in Alzheimer disease: An immu-no-electron microscopy study
-
Nixon RA, Wegiel J, Cuervo AM, et al. Extensive in-volvement of autophagy in Alzheimer disease: an immu-no-electron microscopy study. J Neuropathol Exp Neurol. 2005;64:113-122.
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Cuervo, A.M.3
-
45
-
-
67650264904
-
A central role for autophagy in Alzheimer-type neurodegeneration
-
Ling D, Salvaterra PM. A central role for autophagy in Alzheimer-type neurodegeneration. Autophagy. 2009;5: 738-740.
-
(2009)
Autophagy
, vol.5
, pp. 738-740
-
-
Ling, D.1
Salvaterra, P.M.2
-
46
-
-
45749114895
-
The autopha-gy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta ac-cumulation in mice
-
Pickford F, Masliah E, Wyss-Coray T, et al. The autopha-gy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta ac-cumulation in mice. J Clin Invest. 2008;118:2190-2199.
-
(2008)
J Clin Invest
, vol.118
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Wyss-Coray, T.3
-
47
-
-
0001509014
-
Paralysis Agitans
-
M. Lewandowsky, ed., Berlin: Springer-Verlag
-
Lewy FH. Paralysis Agitans. In: M. Lewandowsky, ed. Handbuch der Neurologie. Berlin: Springer-Verlag. 1912.
-
(1912)
Handbuch Der Neurologie
-
-
Lewy, F.H.1
-
48
-
-
0032492689
-
Regulation of phospholipase D2: Selective inhibition of mammalian pho-spholipase D isoenzymes by alpha- and beta-synucleins
-
Jenco JM, Rawlingson A, Morris AJ, et al. Regulation of phospholipase D2: selective inhibition of mammalian pho-spholipase D isoenzymes by alpha- and beta-synucleins. Biochemistry. 1998;37:4901-4909.
-
(1998)
Biochemistry
, vol.37
, pp. 4901-4909
-
-
Jenco, J.M.1
Rawlingson, A.2
Morris, A.J.3
-
49
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigro-striatal dopamine system
-
Abeliovich A, Schmitz Y, Fariñas I, et al. Mice lacking alpha-synuclein display functional deficits in the nigro-striatal dopamine system. Neuron. 2000;25:239-252.
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Fariñas, I.3
-
50
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Par-kinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the alpha-synuclein gene identified in families with Par-kinson's disease. Science. 1997;276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
52
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chape-rone-mediated autophagy
-
Cuervo AM, Stefanis L, Fredenburg R, et al. Impaired degradation of mutant alpha-synuclein by chape-rone-mediated autophagy. Science. 2004;305:1292-1295.
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
-
53
-
-
13544273998
-
Caspase-dependent and -independent neu-ronal death: Two distinct pathways to neuronal injury
-
Stefanis L. Caspase-dependent and -independent neu-ronal death: two distinct pathways to neuronal injury. Neuroscientist. 2005;11:50-62.
-
(2005)
Neuroscientist
, vol.11
, pp. 50-62
-
-
Stefanis, L.1
-
54
-
-
77952242572
-
The Parkin-son-associated protein PINK1 interacts with Beclin1 and promotes autophagy
-
Michiorri S, Gelmetti V, Giarda E, et al. The Parkin-son-associated protein PINK1 interacts with Beclin1 and promotes autophagy. Cell Death Differ. 2010;17:962-974.
-
(2010)
Cell Death Differ
, vol.17
, pp. 962-974
-
-
Michiorri, S.1
Gelmetti, V.2
Giarda, E.3
-
55
-
-
0036500862
-
Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: Relevance to Huntington's disease
-
Hoffner G, Kahlem P, Djian P. Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease. J Cell Sci. 2002;115:941-948.
-
(2002)
J Cell Sci
, vol.115
, pp. 941-948
-
-
Hoffner, G.1
Kahlem, P.2
Djian, P.3
-
56
-
-
45149107487
-
Mechanisms of neurodegeneration in Huntington's disease
-
Gil JM, Rego AC. Mechanisms of neurodegeneration in Huntington's disease. Eur J Neurosci. 2008;27:2803-2820.
-
(2008)
Eur J Neurosci
, vol.27
, pp. 2803-2820
-
-
Gil, J.M.1
Rego, A.C.2
-
57
-
-
0030771894
-
Huntingtin localization in brains of normal and Huntington's disease patients
-
Sapp E, Schwarz C, Chase K, et al. Huntingtin localization in brains of normal and Huntington's disease patients. Ann Neurol. 1997;42:604-612.
-
(1997)
Ann Neurol
, vol.42
, pp. 604-612
-
-
Sapp, E.1
Schwarz, C.2
Chase, K.3
-
58
-
-
77957565855
-
Age at onset in Huntington's disease is modified by the autophagy path-way: Implication of the V471A polymorphism in Atg7
-
Metzger S, Saukko M, Van Che H, et al. Age at onset in Huntington's disease is modified by the autophagy path-way: implication of the V471A polymorphism in Atg7. Hum Genet. 2010;128:453-459.
-
(2010)
Hum Genet
, vol.128
, pp. 453-459
-
-
Metzger, S.1
Saukko, M.2
van Che, H.3
-
59
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 1993;362: 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
60
-
-
23844458044
-
Inhibition of chape-rone activity is a shared property of several Cu,Zn-su-peroxide dismutase mutants that cause amyotrophic lat-eral sclerosis
-
Tummala H, Jung C, Tiwari A, et al. Inhibition of chape-rone activity is a shared property of several Cu,Zn-su-peroxide dismutase mutants that cause amyotrophic lat-eral sclerosis. J Biol Chem. 2005;280:17725-17731.
-
(2005)
J Biol Chem
, vol.280
, pp. 17725-17731
-
-
Tummala, H.1
Jung, C.2
Tiwari, A.3
-
61
-
-
33749632259
-
Ubiquiti-nated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M, Sampathu DM, Kwong LK, et al. Ubiquiti-nated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science. 2006;314:130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
-
62
-
-
72649087184
-
Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin- proteasome system
-
Wang X, Fan H, Ying Z, et al. Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin- proteasome system. Neurosci Lett. 2010;469:112-116.
-
(2010)
Neurosci Lett
, vol.469
, pp. 112-116
-
-
Wang, X.1
Fan, H.2
Ying, Z.3
-
63
-
-
70349612498
-
Autophagy for the avoidance of neurodegeneration
-
Madeo F, Eisenberg T, Kroemer G. Autophagy for the avoidance of neurodegeneration. Genes Dev. 2009;23: 2253-2259.
-
(2009)
Genes Dev
, vol.23
, pp. 2253-2259
-
-
Madeo, F.1
Eisenberg, T.2
Kroemer, G.3
-
64
-
-
67749106389
-
Autophagy, lithium, and amyotrophic lateral sclerosis
-
Pasquali L, Longone P, Isidoro C, et al. Autophagy, lithium, and amyotrophic lateral sclerosis. Muscle Nerve. 2009;40:173-194.
-
(2009)
Muscle Nerve
, vol.40
, pp. 173-194
-
-
Pasquali, L.1
Longone, P.2
Isidoro, C.3
-
65
-
-
20844436120
-
Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: A consensus statement
-
Freedman MS, Thompson EJ, Deisenhammer F, et al. Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement. Arch Neurol. 2005;62:865-870.
-
(2005)
Arch Neurol
, vol.62
, pp. 865-870
-
-
Freedman, M.S.1
Thompson, E.J.2
Deisenhammer, F.3
-
66
-
-
33749531942
-
Autophagy is induced in CD4+ T cells and important for the growth fac-tor-withdrawal cell death
-
Li C, Capan E, Zhao Y, et al. Autophagy is induced in CD4+ T cells and important for the growth fac-tor-withdrawal cell death. J Immunol. 2006;177:5163-5168.
-
(2006)
J Immunol
, vol.177
, pp. 5163-5168
-
-
Li, C.1
Capan, E.2
Zhao, Y.3
-
67
-
-
33846461678
-
A critical role for the autophagy gene Atg5 in T cell survival and proliferation
-
Pua HH, Dzhagalov I, Chuck M, et al. A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med. 2007;204:25-31.
-
(2007)
J Exp Med
, vol.204
, pp. 25-31
-
-
Pua, H.H.1
Dzhagalov, I.2
Chuck, M.3
-
68
-
-
34248583745
-
Maintaining T lymphocyte homeostasis: Another duty of autophagy
-
Pua HH, He YW. Maintaining T lymphocyte homeostasis: another duty of autophagy. Autophagy. 2007;3:266-267.
-
(2007)
Autophagy
, vol.3
, pp. 266-267
-
-
Pua, H.H.1
He, Y.W.2
-
69
-
-
61649092566
-
Elevated ATG5 ex-pression in autoimmune demyelination and multiple scle-rosis
-
Alirezaei M, Fox HS, Flynn CT, et al. Elevated ATG5 ex-pression in autoimmune demyelination and multiple scle-rosis. Autophagy. 2009;5:152-158.
-
(2009)
Autophagy
, vol.5
, pp. 152-158
-
-
Alirezaei, M.1
Fox, H.S.2
Flynn, C.T.3
-
70
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenera-tive disease in mice
-
Hara T, Nakamura K, Matsui M, et al. Suppression of basal autophagy in neural cells causes neurodegenera-tive disease in mice. Nature. 2006;441:885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
-
71
-
-
41449106674
-
The autophagy gene ATG5 plays an essential role in B lymphocyte de-velopment
-
Miller BC, Zhao Z, Stephenson LM, et al. The autophagy gene ATG5 plays an essential role in B lymphocyte de-velopment. Autophagy. 2008;4:309-314.
-
(2008)
Autophagy
, vol.4
, pp. 309-314
-
-
Miller, B.C.1
Zhao, Z.2
Stephenson, L.M.3
-
72
-
-
0024475202
-
Delayed increase of Ca2+ influx elicited by glutamate: Role in neuronal death
-
Manev H, Favaron M, Guidotti A, et al. Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death. Mol Pharmacol. 1989;36:106-112.
-
(1989)
Mol Pharmacol
, vol.36
, pp. 106-112
-
-
Manev, H.1
Favaron, M.2
Guidotti, A.3
-
73
-
-
46849122006
-
Mitochondrial defects in acute multiple sclerosis lesions
-
Mahad D, Ziabreva I, Lassmann H, et al. Mitochondrial defects in acute multiple sclerosis lesions. Brain. 2008; 131:1722-1735.
-
(2008)
Brain
, vol.131
, pp. 1722-1735
-
-
Mahad, D.1
Ziabreva, I.2
Lassmann, H.3
-
74
-
-
22244491605
-
Closed head injury in-duces upregulation of Beclin 1 at the cortical site of injury
-
Diskin T, Tal-Or P, Erlich S, et al. Closed head injury in-duces upregulation of Beclin 1 at the cortical site of injury. J Neurotrauma. 2005;22:750-762.
-
(2005)
J Neurotrauma
, vol.22
, pp. 750-762
-
-
Diskin, T.1
Tal-Or, P.2
Erlich, S.3
-
75
-
-
59149107439
-
Profiles and electro-physiology of doublecortin-expressing cells in the sub-ventricular zone after ischemic stroke
-
Liu XS, Chopp M, Zhang XG, et al. Profiles and electro-physiology of doublecortin-expressing cells in the sub-ventricular zone after ischemic stroke. J Cereb Blood Flow Metab. 2009;29:297-307.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 297-307
-
-
Liu, X.S.1
Chopp, M.2
Zhang, X.G.3
-
76
-
-
0042380209
-
N-methyl-d- aspartate-triggered neuronal death in organotypic hippo-campal cultures is endocytic, autophagic and mediated by the c-Jun N-terminal kinase pathway
-
Borsello T, Croquelois K, Hornung JP, et al. N-methyl-d- aspartate-triggered neuronal death in organotypic hippo-campal cultures is endocytic, autophagic and mediated by the c-Jun N-terminal kinase pathway. Eur J Neurosci. 2003;18:473-485.
-
(2003)
Eur J Neurosci
, vol.18
, pp. 473-485
-
-
Borsello, T.1
Croquelois, K.2
Hornung, J.P.3
-
77
-
-
38949119423
-
Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3
-
Azad MB, Chen Y, Henson ES, et al. Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3. Autophagy. 2008; 4:195-204.
-
(2008)
Autophagy
, vol.4
, pp. 195-204
-
-
Azad, M.B.1
Chen, Y.2
Henson, E.S.3
-
78
-
-
50249189191
-
Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways
-
Wen YD, Sheng R, Zhang LS, et al. Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways. Autophagy. 2008;4:762-769.
-
(2008)
Autophagy
, vol.4
, pp. 762-769
-
-
Wen, Y.D.1
Sheng, R.2
Zhang, L.S.3
-
79
-
-
56349126024
-
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
-
Carloni S, Buonocore G, Balduini W. Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. Neurobiol Dis. 2008;32:329-339.
-
(2008)
Neurobiol Dis
, vol.32
, pp. 329-339
-
-
Carloni, S.1
Buonocore, G.2
Balduini, W.3
-
80
-
-
33947219280
-
Rapamycin is a neuroprotective treatment for traumatic brain injury
-
Erlich S, Alexandrovich A, Shohami E, et al. Rapamycin is a neuroprotective treatment for traumatic brain injury. Neurobiol Dis. 2007;26:86-93.
-
(2007)
Neurobiol Dis
, vol.26
, pp. 86-93
-
-
Erlich, S.1
Alexandrovich, A.2
Shohami, E.3
-
81
-
-
34548068863
-
Apoptosis and autophagy in photoreceptors exposed to oxidative stress
-
Kunchithapautham K, Rohrer B. Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy. 2007;3:433-441.
-
(2007)
Autophagy
, vol.3
, pp. 433-441
-
-
Kunchithapautham, K.1
Rohrer, B.2
-
82
-
-
79956011038
-
Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice
-
Luo CL, Li BX, Li QQ, et al. Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice. Neuroscience. 2011; 184:54-63.
-
(2011)
Neuroscience
, vol.184
, pp. 54-63
-
-
Luo, C.L.1
Li, B.X.2
Li, Q.Q.3
-
83
-
-
84866282616
-
The role of mTOR signaling pathway in spinal cord injury
-
Kanno H, Ozawa H, Sekiguchi A, et al. The role of mTOR signaling pathway in spinal cord injury. Cell Cycle. 2012;11:3175-3179.
-
(2012)
Cell Cycle
, vol.11
, pp. 3175-3179
-
-
Kanno, H.1
Ozawa, H.2
Sekiguchi, A.3
-
84
-
-
84858800745
-
Autophagy is activated in injured neurons and inhibited by methylprednisolone after experimental spinal cord injury
-
Chen HC, Fong TH, Lee AW, et al. Autophagy is activated in injured neurons and inhibited by methylprednisolone after experimental spinal cord injury. Spine (Phila Pa 1976). 2012;37:470-475.
-
(2012)
Spine (Phila Pa 1976)
, vol.37
, pp. 470-475
-
-
Chen, H.C.1
Fong, T.H.2
Lee, A.W.3
-
85
-
-
84868709247
-
Tetracycline Inhibits Local Inflammation Induced by Cerebral Ischemia via Modulat-ing Autophagy
-
Jiang Y, Zhu J, Wu L, et al. Tetracycline Inhibits Local Inflammation Induced by Cerebral Ischemia via Modulat-ing Autophagy. PLoS One. 2012;7:e48672.
-
(2012)
PLoS One
, pp. 7
-
-
Jiang, Y.1
Zhu, J.2
Wu, L.3
-
86
-
-
84886687428
-
In search of new targets for retinal neuroprotection: Is there a role for au-tophagy?
-
in press
-
Russo R, Berliocchi L, Adornetto A et al. In search of new targets for retinal neuroprotection: is there a role for au-tophagy? Curr Opin Pharmacol. in press.
-
Curr Opin Pharmacol
-
-
Russo, R.1
Berliocchi, L.2
Adornetto, A.3
|