Parkinson's disease in a dish - Using stem cells as a molecular tool

Neuropharmacology

Volumn 76, Issue PART A, 2014, Pages 88-96

  Badger, J L ^a   Cordero Llana, O ^a   Hartfield, E M ^a,b   Wade Martins, R ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Alpha synuclein; Dopaminergic neurons; Glucocerebrosidase; Induced pluripotent stem cell; Leucine rich repeat kinase 2; Parkin; Parkinson's disease; PINK1

Indexed keywords

ALPHA SYNUCLEIN; GLUCOSYLCERAMIDASE; LEUCINE RICH REPEAT KINASE 2; PARKIN;

CALCIUM HOMEOSTASIS; CELL DEATH; DOPAMINERGIC NERVE CELL; GBA1 GENE; GENE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENE MUTATION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; LRRK2 GENE; MISSENSE MUTATION; NEUROTRANSMISSION; PARK 2; PARKINSON DISEASE; PATHOGENESIS; PHENOTYPE; PINK1 GENE; PLURIPOTENT STEM CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING; REVIEW; SNCA GENE;

ALPHA SYNUCLEIN; CHAPERONE MEDIATED AUTOPHAGY; CMA; DA; DAT; DOPAMINE; DOPAMINE ACTIVE TRANSPORTER; DOPAMINERGIC NEURONS; ENDOPLASMIC RETICULUM; ER; GCASE; GENOME WIDE ASSOCIATION ANALYSIS; GLUCOCEREBROSIDASE; GLUTATHIONE SYNTHASE; GSH; GWAS; HEAT SHOCK 27 KDA PROTEIN 1; HESC; HSPB1; HUMAN EMBRYONIC STEM CELL; INDUCED PLURIPOTENT STEM CELL; IPSC; LEUCINE RICH REPEAT KINASE 2; LRRK2; MAPT; MICROTUBULE ASSOCIATED PROTEIN TAU; MIXED LINEAGE KINASE; MLK; MOA; MONOAMINE OXIDASE; OS; OXIDATIVE STRESS; PARKIN; PARKINSON'S DISEASE; PD; PINK1; PTEN INDUCED KINASE 1; TH; TYROSINE HYDROXYLASE; ZFN; ZINC FINGER NUCLEASE; Α-SYN;

ALPHA-SYNUCLEIN; CELL DIFFERENTIATION; DOPAMINERGIC NEURONS; GLUCOSYLCERAMIDASE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MODELS, GENETIC; MUTATION; PARKINSON DISEASE; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 84886595273     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.08.035     Document Type: Review

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