메뉴 건너뛰기




Volumn 14, Issue 1, 2013, Pages

Reversible, interrelated mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts: Functional and mechanistic implications

Author keywords

Cell cycle; Differential gene expression; HRAS; KRAS; miRNA; mRNA; NRAS; Ras; Transcriptional responses; Transcriptome

Indexed keywords

B RAF KINASE; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; DNA; K RAS PROTEIN; MESSENGER RNA; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MYC PROTEIN; PROTEIN MIR 106A; PROTEIN MIR 106B; PROTEIN MIR 17; PROTEIN MIR 183; PROTEIN MIR 212; PROTEIN MIR 335; PROTEIN P53; RETINOBLASTOMA PROTEIN; RNA; TRANSCRIPTION FACTOR E2F; TRANSCRIPTOME; UNCLASSIFIED DRUG; BRAF PROTEIN, MOUSE; MAP2K1 PROTEIN, MOUSE; RAS PROTEIN;

EID: 84886228790     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-14-731     Document Type: Article
Times cited : (13)

References (115)
  • 1
    • 79960038169 scopus 로고    scopus 로고
    • Functional specificity of ras isoforms: so similar but so different
    • 10.1177/1947601911408081, 3128637, 21779495
    • Castellano E, Santos E. Functional specificity of ras isoforms: so similar but so different. Genes Cancer 2011, 2:216-231. 10.1177/1947601911408081, 3128637, 21779495.
    • (2011) Genes Cancer , vol.2 , pp. 216-231
    • Castellano, E.1    Santos, E.2
  • 2
    • 45849130495 scopus 로고    scopus 로고
    • Ras oncogenes: split personalities
    • 10.1038/nrm2438, 18568040
    • Karnoub AE, Weinberg RA. Ras oncogenes: split personalities. Nat Rev Mol Cell Biol 2008, 9:517-531. 10.1038/nrm2438, 18568040.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 517-531
    • Karnoub, A.E.1    Weinberg, R.A.2
  • 3
    • 79960066478 scopus 로고    scopus 로고
    • Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives
    • 10.1177/1947601911408078, 3128634, 21779500
    • Rojas JM, Oliva JL, Santos E. Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives. Genes Cancer 2011, 2:298-305. 10.1177/1947601911408078, 3128634, 21779500.
    • (2011) Genes Cancer , vol.2 , pp. 298-305
    • Rojas, J.M.1    Oliva, J.L.2    Santos, E.3
  • 4
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 2003, 3:11-22.
    • (2003) Nat Rev Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 5
    • 0023098381 scopus 로고
    • Differential expression of the ras gene family in mice
    • 365242, 3600635
    • Leon J, Guerrero I, Pellicer A. Differential expression of the ras gene family in mice. Mol Cell Biol 1987, 7:1535-1540. 365242, 3600635.
    • (1987) Mol Cell Biol , vol.7 , pp. 1535-1540
    • Leon, J.1    Guerrero, I.2    Pellicer, A.3
  • 6
    • 0023933429 scopus 로고
    • All three human ras genes are expressed in a wide range of tissues
    • 10.1016/0167-4781(88)90076-0, 3282543
    • Fiorucci G, Hall A. All three human ras genes are expressed in a wide range of tissues. Biochim Biophys Acta 1988, 950:81-83. 10.1016/0167-4781(88)90076-0, 3282543.
    • (1988) Biochim Biophys Acta , vol.950 , pp. 81-83
    • Fiorucci, G.1    Hall, A.2
  • 7
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: a review
    • Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989, 49:4682-4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 8
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: the first 30 years
    • 10.1038/nrc1097, 12778136
    • Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer 2003, 3:459-465. 10.1038/nrc1097, 12778136.
    • (2003) Nat Rev Cancer , vol.3 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 9
    • 79960052850 scopus 로고    scopus 로고
    • Ras in cancer and developmental diseases
    • 10.1177/1947601911411084, 3128640, 21779504
    • Fernandez-Medarde A, Santos E. Ras in cancer and developmental diseases. Genes Cancer 2011, 2:344-358. 10.1177/1947601911411084, 3128640, 21779504.
    • (2011) Genes Cancer , vol.2 , pp. 344-358
    • Fernandez-Medarde, A.1    Santos, E.2
  • 10
    • 0037542854 scopus 로고    scopus 로고
    • Ras proteins: different signals from different locations
    • 10.1038/nrm1105, 12728271
    • Hancock JF. Ras proteins: different signals from different locations. Nat Rev Mol Cell Biol 2003, 4:373-384. 10.1038/nrm1105, 12728271.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 373-384
    • Hancock, J.F.1
  • 11
    • 33644856168 scopus 로고    scopus 로고
    • Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation
    • 10.1128/MCB.26.1.100-116.2006, 1317613, 16354683
    • Matallanas D, Sanz-Moreno V, Arozarena I, Calvo F, Agudo-Ibanez L, Santos E, Berciano MT, Crespo P. Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation. Mol Cell Biol 2006, 26:100-116. 10.1128/MCB.26.1.100-116.2006, 1317613, 16354683.
    • (2006) Mol Cell Biol , vol.26 , pp. 100-116
    • Matallanas, D.1    Sanz-Moreno, V.2    Arozarena, I.3    Calvo, F.4    Agudo-Ibanez, L.5    Santos, E.6    Berciano, M.T.7    Crespo, P.8
  • 12
    • 0034175984 scopus 로고    scopus 로고
    • Understanding Ras: 'it ain't over 'til it's over'
    • 10.1016/S0962-8924(00)01740-2, 10740269
    • Shields JM, Pruitt K, McFall A, Shaub A, Der CJ. Understanding Ras: 'it ain't over 'til it's over'. Trends Cell Biol 2000, 10:147-154. 10.1016/S0962-8924(00)01740-2, 10740269.
    • (2000) Trends Cell Biol , vol.10 , pp. 147-154
    • Shields, J.M.1    Pruitt, K.2    McFall, A.3    Shaub, A.4    Der, C.J.5
  • 13
    • 0035136213 scopus 로고    scopus 로고
    • Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development
    • 10.1128/MCB.21.5.1444-1452.2001, 86690, 11238881
    • Esteban LM, Vicario-Abejon C, Fernandez-Salguero P, Fernandez-Medarde A, Swaminathan N, Yienger K, Lopez E, Malumbres M, McKay R, Ward JM, et al. Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development. Mol Cell Biol 2001, 21:1444-1452. 10.1128/MCB.21.5.1444-1452.2001, 86690, 11238881.
    • (2001) Mol Cell Biol , vol.21 , pp. 1444-1452
    • Esteban, L.M.1    Vicario-Abejon, C.2    Fernandez-Salguero, P.3    Fernandez-Medarde, A.4    Swaminathan, N.5    Yienger, K.6    Lopez, E.7    Malumbres, M.8    McKay, R.9    Ward, J.M.10
  • 15
    • 0028907331 scopus 로고
    • The murine N-ras gene is not essential for growth and development
    • 10.1073/pnas.92.5.1709, 42589, 7878045
    • Umanoff H, Edelmann W, Pellicer A, Kucherlapati R. The murine N-ras gene is not essential for growth and development. Proc Natl Acad Sci USA 1995, 92:1709-1713. 10.1073/pnas.92.5.1709, 42589, 7878045.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1709-1713
    • Umanoff, H.1    Edelmann, W.2    Pellicer, A.3    Kucherlapati, R.4
  • 18
    • 20044363093 scopus 로고    scopus 로고
    • Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice
    • 10.1038/sj.embor.7400397, 1299307, 15864294
    • Potenza N, Vecchione C, Notte A, De Rienzo A, Rosica A, Bauer L, Affuso A, De Felice M, Russo T, Poulet R, et al. Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice. EMBO Rep 2005, 6:432-437. 10.1038/sj.embor.7400397, 1299307, 15864294.
    • (2005) EMBO Rep , vol.6 , pp. 432-437
    • Potenza, N.1    Vecchione, C.2    Notte, A.3    De Rienzo, A.4    Rosica, A.5    Bauer, L.6    Affuso, A.7    De Felice, M.8    Russo, T.9    Poulet, R.10
  • 20
    • 33846942620 scopus 로고    scopus 로고
    • Transcriptional networks of knockout cell lines identify functional specificities of H-Ras and N-Ras: significant involvement of N-Ras in biotic and defense responses
    • 10.1038/sj.onc.1209845, 16909116
    • Castellano E, De Las Rivas J, Guerrero C, Santos E. Transcriptional networks of knockout cell lines identify functional specificities of H-Ras and N-Ras: significant involvement of N-Ras in biotic and defense responses. Oncogene 2007, 26:917-933. 10.1038/sj.onc.1209845, 16909116.
    • (2007) Oncogene , vol.26 , pp. 917-933
    • Castellano, E.1    De Las Rivas, J.2    Guerrero, C.3    Santos, E.4
  • 21
    • 76249117627 scopus 로고    scopus 로고
    • Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle
    • 10.1186/gb-2009-10-11-r123, 3091317, 19895680
    • Castellano E, Guerrero C, Nunez A, De Las Rivas J, Santos E. Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle. Genome Biol 2009, 10:R123. 10.1186/gb-2009-10-11-r123, 3091317, 19895680.
    • (2009) Genome Biol , vol.10
    • Castellano, E.1    Guerrero, C.2    Nunez, A.3    De Las Rivas, J.4    Santos, E.5
  • 22
    • 30444451291 scopus 로고    scopus 로고
    • Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line
    • 10.1002/ijc.21386, 16152623
    • Roberts ML, Drosopoulos KG, Vasileiou I, Stricker M, Taoufik E, Maercker C, Guialis A, Alexis MN, Pintzas A. Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line. Int J Cancer 2006, 118:616-627. 10.1002/ijc.21386, 16152623.
    • (2006) Int J Cancer , vol.118 , pp. 616-627
    • Roberts, M.L.1    Drosopoulos, K.G.2    Vasileiou, I.3    Stricker, M.4    Taoufik, E.5    Maercker, C.6    Guialis, A.7    Alexis, M.N.8    Pintzas, A.9
  • 24
    • 2942534604 scopus 로고    scopus 로고
    • Gene expression profiling by DNA microarray analysis in mouse embryonic fibroblasts transformed by rasV12 mutated protein and the E1A oncogene
    • 10.1186/1476-4598-2-19, 153489, 12685932
    • Vasseur S, Malicet C, Calvo EL, Labrie C, Berthezene P, Dagorn JC, Iovanna JL. Gene expression profiling by DNA microarray analysis in mouse embryonic fibroblasts transformed by rasV12 mutated protein and the E1A oncogene. Mol Cancer 2003, 2:19. 10.1186/1476-4598-2-19, 153489, 12685932.
    • (2003) Mol Cancer , vol.2 , pp. 19
    • Vasseur, S.1    Malicet, C.2    Calvo, E.L.3    Labrie, C.4    Berthezene, P.5    Dagorn, J.C.6    Iovanna, J.L.7
  • 25
    • 49749125587 scopus 로고    scopus 로고
    • A Proteomic approach for protein-profiling the oncogenic ras induced transformation (H-, K-, and N-Ras) in NIH/3T3 mouse embryonic fibroblasts
    • 10.1002/pmic.200800106, 18601226
    • Kim S, Lee YZ, Kim YS, Bahk YY. A Proteomic approach for protein-profiling the oncogenic ras induced transformation (H-, K-, and N-Ras) in NIH/3T3 mouse embryonic fibroblasts. Proteomics 2008, 8:3082-3093. 10.1002/pmic.200800106, 18601226.
    • (2008) Proteomics , vol.8 , pp. 3082-3093
    • Kim, S.1    Lee, Y.Z.2    Kim, Y.S.3    Bahk, Y.Y.4
  • 26
    • 0141481982 scopus 로고    scopus 로고
    • Gene profiling of a myeloma cell line reveals similarities and unique signatures among IL-6 response, N-ras-activating mutations, and coculture with bone marrow stromal cells
    • 10.1182/blood-2003-04-1227, 12791645
    • Croonquist PA, Linden MA, Zhao F, Van Ness BG. Gene profiling of a myeloma cell line reveals similarities and unique signatures among IL-6 response, N-ras-activating mutations, and coculture with bone marrow stromal cells. Blood 2003, 102:2581-2592. 10.1182/blood-2003-04-1227, 12791645.
    • (2003) Blood , vol.102 , pp. 2581-2592
    • Croonquist, P.A.1    Linden, M.A.2    Zhao, F.3    Van Ness, B.G.4
  • 27
    • 0033618410 scopus 로고    scopus 로고
    • Multiple ras effector pathways contribute to G(1) cell cycle progression
    • 10.1074/jbc.274.31.22033, 10419529
    • Gille H, Downward J. Multiple ras effector pathways contribute to G(1) cell cycle progression. J Biol Chem 1999, 274:22033-22040. 10.1074/jbc.274.31.22033, 10419529.
    • (1999) J Biol Chem , vol.274 , pp. 22033-22040
    • Gille, H.1    Downward, J.2
  • 28
    • 0036467497 scopus 로고    scopus 로고
    • Regulation of Ras signaling by the cell cycle
    • 10.1016/S0959-437X(01)00262-3, 11790553
    • Stacey D, Kazlauskas A. Regulation of Ras signaling by the cell cycle. Curr Opin Genet Dev 2002, 12:44-46. 10.1016/S0959-437X(01)00262-3, 11790553.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 44-46
    • Stacey, D.1    Kazlauskas, A.2
  • 29
    • 0035150990 scopus 로고    scopus 로고
    • Growth-factor-dependent mitogenesis requires two distinct phases of signalling
    • 10.1038/35055073, 11175749
    • Jones SM, Kazlauskas A. Growth-factor-dependent mitogenesis requires two distinct phases of signalling. Nat Cell Biol 2001, 3:165-172. 10.1038/35055073, 11175749.
    • (2001) Nat Cell Biol , vol.3 , pp. 165-172
    • Jones, S.M.1    Kazlauskas, A.2
  • 31
    • 34547120690 scopus 로고    scopus 로고
    • Concise review: stem cell antigen-1: expression, function, and enigma
    • 10.1634/stemcells.2006-0644, 17379763
    • Holmes C, Stanford WL. Concise review: stem cell antigen-1: expression, function, and enigma. Stem Cells 2007, 25:1339-1347. 10.1634/stemcells.2006-0644, 17379763.
    • (2007) Stem Cells , vol.25 , pp. 1339-1347
    • Holmes, C.1    Stanford, W.L.2
  • 32
    • 82255195416 scopus 로고    scopus 로고
    • Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration
    • 10.1371/journal.pone.0027841, 3226565, 22140470
    • Batts TD, Machado HL, Zhang Y, Creighton CJ, Li Y, Rosen JM. Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration. PLoS One 2011, 6:e27841. 10.1371/journal.pone.0027841, 3226565, 22140470.
    • (2011) PLoS One , vol.6
    • Batts, T.D.1    Machado, H.L.2    Zhang, Y.3    Creighton, C.J.4    Li, Y.5    Rosen, J.M.6
  • 34
    • 20444474599 scopus 로고    scopus 로고
    • Sca-1 negatively regulates proliferation and differentiation of muscle cells
    • 10.1016/j.ydbio.2005.04.016, 15901485
    • Mitchell PO, Mills T, O'Connor RS, Kline ER, Graubert T, Dzierzak E, Pavlath GK. Sca-1 negatively regulates proliferation and differentiation of muscle cells. Dev Biol 2005, 283:240-252. 10.1016/j.ydbio.2005.04.016, 15901485.
    • (2005) Dev Biol , vol.283 , pp. 240-252
    • Mitchell, P.O.1    Mills, T.2    O'Connor, R.S.3    Kline, E.R.4    Graubert, T.5    Dzierzak, E.6    Pavlath, G.K.7
  • 35
    • 0034949169 scopus 로고    scopus 로고
    • Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
    • 10.1128/MCB.21.14.4684-4699.2001, 87143, 11416145
    • Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, Nevins JR. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol 2001, 21:4684-4699. 10.1128/MCB.21.14.4684-4699.2001, 87143, 11416145.
    • (2001) Mol Cell Biol , vol.21 , pp. 4684-4699
    • Ishida, S.1    Huang, E.2    Zuzan, H.3    Spang, R.4    Leone, G.5    West, M.6    Nevins, J.R.7
  • 36
    • 0037088536 scopus 로고    scopus 로고
    • Identification of novel E2F1-regulated genes by microarray
    • 10.1006/abbi.2002.2761, 11888208
    • Ma Y, Croxton R, Moorer RL, Cress WD. Identification of novel E2F1-regulated genes by microarray. Arch Biochem Biophys 2002, 399:212-224. 10.1006/abbi.2002.2761, 11888208.
    • (2002) Arch Biochem Biophys , vol.399 , pp. 212-224
    • Ma, Y.1    Croxton, R.2    Moorer, R.L.3    Cress, W.D.4
  • 37
    • 5444240769 scopus 로고    scopus 로고
    • Hitting their targets: an emerging picture of E2F and cell cycle control
    • 10.1016/j.gde.2004.07.003, 15380244
    • Blais A, Dynlacht BD. Hitting their targets: an emerging picture of E2F and cell cycle control. Curr Opin Genet Dev 2004, 14:527-532. 10.1016/j.gde.2004.07.003, 15380244.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 527-532
    • Blais, A.1    Dynlacht, B.D.2
  • 39
    • 0030989155 scopus 로고    scopus 로고
    • Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1
    • 232237, 9199319
    • Aktas H, Cai H, Cooper GM. Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1. Mol Cell Biol 1997, 17:3850-3857. 232237, 9199319.
    • (1997) Mol Cell Biol , vol.17 , pp. 3850-3857
    • Aktas, H.1    Cai, H.2    Cooper, G.M.3
  • 40
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: expanding roles and emerging paradigms
    • 10.1101/gad.813200, 11018009
    • Harbour JW, Dean DC. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev 2000, 14:2393-2409. 10.1101/gad.813200, 11018009.
    • (2000) Genes Dev , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 41
    • 0036901897 scopus 로고    scopus 로고
    • Loss of Rb overrides the requirement for ERK activity for cell proliferation
    • 10.1242/jcs.00161, 12415005
    • D'Abaco GM, Hooper S, Paterson H, Marshall CJ. Loss of Rb overrides the requirement for ERK activity for cell proliferation. J Cell Sci 2002, 115:4607-4616. 10.1242/jcs.00161, 12415005.
    • (2002) J Cell Sci , vol.115 , pp. 4607-4616
    • D'Abaco, G.M.1    Hooper, S.2    Paterson, H.3    Marshall, C.J.4
  • 42
    • 42449114966 scopus 로고    scopus 로고
    • Transcriptional control of human p53-regulated genes
    • 10.1038/nrm2395, 18431400
    • Riley T, Sontag E, Chen P, Levine A. Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 2008, 9:402-412. 10.1038/nrm2395, 18431400.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 402-412
    • Riley, T.1    Sontag, E.2    Chen, P.3    Levine, A.4
  • 43
    • 33947534030 scopus 로고    scopus 로고
    • P53 in health and disease
    • 10.1038/nrm2147, 17380161
    • Vousden KH, Lane DP. p53 in health and disease. Nat Rev Mol Cell Biol 2007, 8:275-283. 10.1038/nrm2147, 17380161.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 275-283
    • Vousden, K.H.1    Lane, D.P.2
  • 44
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006, 6:259-269.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 45
    • 65249180150 scopus 로고    scopus 로고
    • SnapShot: MicroRNAs in Cancer
    • 10.1016/j.cell.2009.04.040, 19410551
    • Spizzo R, Nicoloso MS, Croce CM, Calin GA. SnapShot: MicroRNAs in Cancer. Cell 2009, 137:586-e581. 10.1016/j.cell.2009.04.040, 19410551.
    • (2009) Cell , vol.137
    • Spizzo, R.1    Nicoloso, M.S.2    Croce, C.M.3    Calin, G.A.4
  • 46
    • 67650711156 scopus 로고    scopus 로고
    • MicroRNAs in Cancer
    • 10.1146/annurev.med.59.053006.104707, 19630570
    • Garzon R, Calin GA, Croce CM. MicroRNAs in Cancer. Annu Rev Med 2009, 60:167-179. 10.1146/annurev.med.59.053006.104707, 19630570.
    • (2009) Annu Rev Med , vol.60 , pp. 167-179
    • Garzon, R.1    Calin, G.A.2    Croce, C.M.3
  • 48
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • 10.1158/0008-5472.CAN-04-0637, 15172979
    • Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, Harano T, Yatabe Y, Nagino M, Nimura Y, et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004, 64:3753-3756. 10.1158/0008-5472.CAN-04-0637, 15172979.
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3    Tomida, S.4    Osada, H.5    Endoh, H.6    Harano, T.7    Yatabe, Y.8    Nagino, M.9    Nimura, Y.10
  • 49
    • 78650194092 scopus 로고    scopus 로고
    • Let-7 and miR-17-92: small-sized major players in lung cancer development
    • 10.1111/j.1349-7006.2010.01707.x, 20735434
    • Osada H, Takahashi T. let-7 and miR-17-92: small-sized major players in lung cancer development. Cancer Sci 2011, 102:9-17. 10.1111/j.1349-7006.2010.01707.x, 20735434.
    • (2011) Cancer Sci , vol.102 , pp. 9-17
    • Osada, H.1    Takahashi, T.2
  • 50
    • 41949102707 scopus 로고    scopus 로고
    • MiRiad roles for the miR-17-92 cluster in development and disease
    • 10.1016/j.cell.2008.04.001, 2732113, 18423194
    • Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell 2008, 133:217-222. 10.1016/j.cell.2008.04.001, 2732113, 18423194.
    • (2008) Cell , vol.133 , pp. 217-222
    • Mendell, J.T.1
  • 51
    • 84868588961 scopus 로고    scopus 로고
    • The miR-17-92 microRNA cluster: a novel diagnostic tool in large B-cell malignancies
    • 10.1038/labinvest.2012.129, 22964854
    • Fassina A, Marino F, Siri M, Zambello R, Ventura L, Fassan M, Simonato F, Cappellesso R. The miR-17-92 microRNA cluster: a novel diagnostic tool in large B-cell malignancies. Lab Invest 2012, 92:1574-1582. 10.1038/labinvest.2012.129, 22964854.
    • (2012) Lab Invest , vol.92 , pp. 1574-1582
    • Fassina, A.1    Marino, F.2    Siri, M.3    Zambello, R.4    Ventura, L.5    Fassan, M.6    Simonato, F.7    Cappellesso, R.8
  • 53
    • 27644570319 scopus 로고    scopus 로고
    • A microRNA cluster as a target of genomic amplification in malignant lymphoma
    • 10.1038/sj.leu.2403942, 16167061
    • Tagawa H, Seto M. A microRNA cluster as a target of genomic amplification in malignant lymphoma. Leukemia 2005, 19:2013-2016. 10.1038/sj.leu.2403942, 16167061.
    • (2005) Leukemia , vol.19 , pp. 2013-2016
    • Tagawa, H.1    Seto, M.2
  • 56
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • 10.1158/0008-5472.CAN-05-2352, 16266980
    • Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y, Takahashi T. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005, 65:9628-9632. 10.1158/0008-5472.CAN-05-2352, 16266980.
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3    Yamada, H.4    Yanagisawa, K.5    Tomida, S.6    Yatabe, Y.7    Kawahara, K.8    Sekido, Y.9    Takahashi, T.10
  • 57
    • 34250879111 scopus 로고    scopus 로고
    • Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia
    • 10.1158/0008-5472.CAN-06-4478, 17575136
    • Landais S, Landry S, Legault P, Rassart E. Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia. Cancer Res 2007, 67:5699-5707. 10.1158/0008-5472.CAN-06-4478, 17575136.
    • (2007) Cancer Res , vol.67 , pp. 5699-5707
    • Landais, S.1    Landry, S.2    Legault, P.3    Rassart, E.4
  • 59
    • 84870868566 scopus 로고    scopus 로고
    • MiR-106a overexpression and pRB downregulation in sporadic colorectal cancer
    • 10.1016/j.yexmp.2012.11.002, 23178825
    • Catela Ivkovic T, Aralica G, Cacev T, Loncar B, Kapitanovic S. miR-106a overexpression and pRB downregulation in sporadic colorectal cancer. Exp Mol Pathol 2013, 94:148-154. 10.1016/j.yexmp.2012.11.002, 23178825.
    • (2013) Exp Mol Pathol , vol.94 , pp. 148-154
    • Catela Ivkovic, T.1    Aralica, G.2    Cacev, T.3    Loncar, B.4    Kapitanovic, S.5
  • 60
    • 84880325375 scopus 로고    scopus 로고
    • MiR-106a Is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS
    • Wang Z, Liu M, Zhu H, Zhang W, He S, Hu C, Quan L, Bai J, Xu N. miR-106a Is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS. Mol Carcinog 2012, 52:634-646.
    • (2012) Mol Carcinog , vol.52 , pp. 634-646
    • Wang, Z.1    Liu, M.2    Zhu, H.3    Zhang, W.4    He, S.5    Hu, C.6    Quan, L.7    Bai, J.8    Xu, N.9
  • 61
    • 77953948708 scopus 로고    scopus 로고
    • Identification of the miR-106b 25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
    • 10.1126/scisignal.2000594, 2982149, 20388916
    • Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM, Sportoletti P, Varmeh S, Egia A, Fedele G, et al. Identification of the miR-106b 25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal 2010, 3:ra29. 10.1126/scisignal.2000594, 2982149, 20388916.
    • (2010) Sci Signal , vol.3
    • Poliseno, L.1    Salmena, L.2    Riccardi, L.3    Fornari, A.4    Song, M.S.5    Hobbs, R.M.6    Sportoletti, P.7    Varmeh, S.8    Egia, A.9    Fedele, G.10
  • 63
    • 67449102314 scopus 로고    scopus 로고
    • Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma
    • 10.1111/j.1349-7006.2009.01164.x, 19486339
    • Li Y, Tan W, Neo TW, Aung MO, Wasser S, Lim SG, Tan TM. Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma. Cancer Sci 2009, 100:1234-1242. 10.1111/j.1349-7006.2009.01164.x, 19486339.
    • (2009) Cancer Sci , vol.100 , pp. 1234-1242
    • Li, Y.1    Tan, W.2    Neo, T.W.3    Aung, M.O.4    Wasser, S.5    Lim, S.G.6    Tan, T.M.7
  • 64
    • 84856366992 scopus 로고    scopus 로고
    • MiR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma
    • 10.1002/hep.24698, 3268937, 21953056
    • Razumilava N, Bronk SF, Smoot RL, Fingas CD, Werneburg NW, Roberts LR, Mott JL. miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma. Hepatology 2012, 55:465-475. 10.1002/hep.24698, 3268937, 21953056.
    • (2012) Hepatology , vol.55 , pp. 465-475
    • Razumilava, N.1    Bronk, S.F.2    Smoot, R.L.3    Fingas, C.D.4    Werneburg, N.W.5    Roberts, L.R.6    Mott, J.L.7
  • 67
    • 84859732471 scopus 로고    scopus 로고
    • MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1
    • 10.1091/mbc.E11-09-0777, 3327317, 22357618
    • Li Y, Zhang D, Chen C, Ruan Z, Huang Y. MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1. Mol Biol Cell 2012, 23:1423-1434. 10.1091/mbc.E11-09-0777, 3327317, 22357618.
    • (2012) Mol Biol Cell , vol.23 , pp. 1423-1434
    • Li, Y.1    Zhang, D.2    Chen, C.3    Ruan, Z.4    Huang, Y.5
  • 70
    • 84862650219 scopus 로고    scopus 로고
    • Pleiotropic effects of miR-183 96 182 converge to regulate cell survival, proliferation and migration in medulloblastoma
    • 10.1007/s00401-012-0969-5, 22402744
    • Weeraratne SD, Amani V, Teider N, Pierre-Francois J, Winter D, Kye MJ, Sengupta S, Archer T, Remke M, Bai AH, et al. Pleiotropic effects of miR-183 96 182 converge to regulate cell survival, proliferation and migration in medulloblastoma. Acta Neuropathol 2012, 123:539-552. 10.1007/s00401-012-0969-5, 22402744.
    • (2012) Acta Neuropathol , vol.123 , pp. 539-552
    • Weeraratne, S.D.1    Amani, V.2    Teider, N.3    Pierre-Francois, J.4    Winter, D.5    Kye, M.J.6    Sengupta, S.7    Archer, T.8    Remke, M.9    Bai, A.H.10
  • 71
    • 80053258276 scopus 로고    scopus 로고
    • Overexpression of members of the microRNA-183 family is a risk factor for lung cancer: a case control study
    • 10.1186/1471-2407-11-393, 3183044, 21920043
    • Zhu W, Liu X, He J, Chen D, Hunag Y, Zhang YK. Overexpression of members of the microRNA-183 family is a risk factor for lung cancer: a case control study. BMC Cancer 2011, 11:393. 10.1186/1471-2407-11-393, 3183044, 21920043.
    • (2011) BMC Cancer , vol.11 , pp. 393
    • Zhu, W.1    Liu, X.2    He, J.3    Chen, D.4    Hunag, Y.5    Zhang, Y.K.6
  • 72
    • 84867164086 scopus 로고    scopus 로고
    • TGF-beta induces miR-182 to sustain NF-kappaB activation in glioma subsets
    • 10.1172/JCI62339, 3589141, 23006329
    • Song L, Liu L, Wu Z, Li Y, Ying Z, Lin C, Wu J, Hu B, Cheng SY, Li M, Li J. TGF-beta induces miR-182 to sustain NF-kappaB activation in glioma subsets. J Clin Invest 2012, 122:3563-3578. 10.1172/JCI62339, 3589141, 23006329.
    • (2012) J Clin Invest , vol.122 , pp. 3563-3578
    • Song, L.1    Liu, L.2    Wu, Z.3    Li, Y.4    Ying, Z.5    Lin, C.6    Wu, J.7    Hu, B.8    Cheng, S.Y.9    Li, M.10    Li, J.11
  • 73
    • 84863631247 scopus 로고    scopus 로고
    • Identification of hsa-miR-335 as a prognostic signature in gastric cancer
    • 10.1371/journal.pone.0040037, 3388997, 22802949
    • Yan Z, Xiong Y, Xu W, Gao J, Cheng Y, Wang Z, Chen F, Zheng G. Identification of hsa-miR-335 as a prognostic signature in gastric cancer. PLoS One 2012, 7:e40037. 10.1371/journal.pone.0040037, 3388997, 22802949.
    • (2012) PLoS One , vol.7
    • Yan, Z.1    Xiong, Y.2    Xu, W.3    Gao, J.4    Cheng, Y.5    Wang, Z.6    Chen, F.7    Zheng, G.8
  • 74
    • 84880301391 scopus 로고    scopus 로고
    • Tumor microRNA-335 expression is associated with poor prognosis in human glioma
    • 10.1007/s12032-012-0259-z, 22644918
    • Jiang J, Sun X, Wang W, Jin X, Bo X, Li Z, Bian A, Jiu J, Wang X, Liu D, et al. Tumor microRNA-335 expression is associated with poor prognosis in human glioma. Med Oncol 2012, 29:3472-3477. 10.1007/s12032-012-0259-z, 22644918.
    • (2012) Med Oncol , vol.29 , pp. 3472-3477
    • Jiang, J.1    Sun, X.2    Wang, W.3    Jin, X.4    Bo, X.5    Li, Z.6    Bian, A.7    Jiu, J.8    Wang, X.9    Liu, D.10
  • 76
    • 62449121929 scopus 로고    scopus 로고
    • MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3
    • 10.4161/cc.8.5.7870, 2804747, 19221487
    • Wang X, Gocek E, Liu CG, Studzinski GP. MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3. Cell Cycle 2009, 8:736-741. 10.4161/cc.8.5.7870, 2804747, 19221487.
    • (2009) Cell Cycle , vol.8 , pp. 736-741
    • Wang, X.1    Gocek, E.2    Liu, C.G.3    Studzinski, G.P.4
  • 77
    • 84856812740 scopus 로고    scopus 로고
    • MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A
    • 10.1182/blood-2011-08-373886, 22184411
    • Urbich C, Kaluza D, Fromel T, Knau A, Bennewitz K, Boon RA, Bonauer A, Doebele C, Boeckel JN, Hergenreider E, et al. MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A. Blood 2012, 119:1607-1616. 10.1182/blood-2011-08-373886, 22184411.
    • (2012) Blood , vol.119 , pp. 1607-1616
    • Urbich, C.1    Kaluza, D.2    Fromel, T.3    Knau, A.4    Bennewitz, K.5    Boon, R.A.6    Bonauer, A.7    Doebele, C.8    Boeckel, J.N.9    Hergenreider, E.10
  • 78
    • 84871038819 scopus 로고    scopus 로고
    • The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis
    • 10.1182/blood-2012-04-423004, 23086751
    • Bridge G, Monteiro R, Henderson S, Emuss V, Lagos D, Georgopoulou D, Patient R, Boshoff C. The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis. Blood 2012, 120:5063-5072. 10.1182/blood-2012-04-423004, 23086751.
    • (2012) Blood , vol.120 , pp. 5063-5072
    • Bridge, G.1    Monteiro, R.2    Henderson, S.3    Emuss, V.4    Lagos, D.5    Georgopoulou, D.6    Patient, R.7    Boshoff, C.8
  • 79
    • 84862219230 scopus 로고    scopus 로고
    • Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene
    • 10.1371/journal.pone.0038847, 3372467, 22701724
    • Tanic M, Yanowsky K, Rodriguez-Antona C, Andres R, Marquez-Rodas I, Osorio A, Benitez J, Martinez-Delgado B. Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene. PLoS One 2012, 7:e38847. 10.1371/journal.pone.0038847, 3372467, 22701724.
    • (2012) PLoS One , vol.7
    • Tanic, M.1    Yanowsky, K.2    Rodriguez-Antona, C.3    Andres, R.4    Marquez-Rodas, I.5    Osorio, A.6    Benitez, J.7    Martinez-Delgado, B.8
  • 80
    • 78651307694 scopus 로고    scopus 로고
    • StarBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
    • 10.1093/nar/gkq1056, 3013664, 21037263
    • Yang JH, Li JH, Shao P, Zhou H, Chen YQ, Qu LH. starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data. Nucleic Acids Res 2011, 39:D202-D209. 10.1093/nar/gkq1056, 3013664, 21037263.
    • (2011) Nucleic Acids Res , vol.39
    • Yang, J.H.1    Li, J.H.2    Shao, P.3    Zhou, H.4    Chen, Y.Q.5    Qu, L.H.6
  • 82
    • 84866723283 scopus 로고    scopus 로고
    • The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentiation
    • 10.1371/journal.pone.0045761, 3454365, 23029228
    • Wu N, Sulpice E, Obeid P, Benzina S, Kermarrec F, Combe S, Gidrol X. The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentiation. PLoS One 2012, 7:e45761. 10.1371/journal.pone.0045761, 3454365, 23029228.
    • (2012) PLoS One , vol.7
    • Wu, N.1    Sulpice, E.2    Obeid, P.3    Benzina, S.4    Kermarrec, F.5    Combe, S.6    Gidrol, X.7
  • 83
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • 10.1038/nature03677, 15944709
    • O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005, 435:839-843. 10.1038/nature03677, 15944709.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3    Dang, C.V.4    Mendell, J.T.5
  • 86
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K, Thomson JM, Hammond SM. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 2007, 282:2130-2134.
    • (2007) J Biol Chem , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 87
    • 68749119636 scopus 로고    scopus 로고
    • MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression
    • 10.1038/sj.bjc.6605037, 2736819, 19672269
    • Diosdado B, van de Wiel MA, Terhaar Sive Droste JS, Mongera S, Postma C, Meijerink WJ, Carvalho B, Meijer GA. MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer 2009, 101:707-714. 10.1038/sj.bjc.6605037, 2736819, 19672269.
    • (2009) Br J Cancer , vol.101 , pp. 707-714
    • Diosdado, B.1    van de Wiel, M.A.2    Terhaar Sive Droste, J.S.3    Mongera, S.4    Postma, C.5    Meijerink, W.J.6    Carvalho, B.7    Meijer, G.A.8
  • 88
    • 34247869960 scopus 로고    scopus 로고
    • Concomitant MYC and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma
    • 10.1080/10428190601059738, 17325905
    • Rinaldi A, Poretti G, Kwee I, Zucca E, Catapano CV, Tibiletti MG, Bertoni F. Concomitant MYC and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma. Leuk Lymphoma 2007, 48:410-412. 10.1080/10428190601059738, 17325905.
    • (2007) Leuk Lymphoma , vol.48 , pp. 410-412
    • Rinaldi, A.1    Poretti, G.2    Kwee, I.3    Zucca, E.4    Catapano, C.V.5    Tibiletti, M.G.6    Bertoni, F.7
  • 89
    • 84860417150 scopus 로고    scopus 로고
    • MiR-17 92 cooperates with RB pathway mutations to promote retinoblastoma
    • 10.1101/gad.17027411, 3165937, 21816922
    • Conkrite K, Sundby M, Mukai S, Thomson JM, Mu D, Hammond SM, MacPherson D. miR-17 92 cooperates with RB pathway mutations to promote retinoblastoma. Genes Dev 2011, 25:1734-1745. 10.1101/gad.17027411, 3165937, 21816922.
    • (2011) Genes Dev , vol.25 , pp. 1734-1745
    • Conkrite, K.1    Sundby, M.2    Mukai, S.3    Thomson, J.M.4    Mu, D.5    Hammond, S.M.6    MacPherson, D.7
  • 91
    • 54249158400 scopus 로고    scopus 로고
    • Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling
    • 10.1158/0008-5472.CAN-08-1768, 18922889
    • Petrocca F, Vecchione A, Croce CM. Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling. Cancer Res 2008, 68:8191-8194. 10.1158/0008-5472.CAN-08-1768, 18922889.
    • (2008) Cancer Res , vol.68 , pp. 8191-8194
    • Petrocca, F.1    Vecchione, A.2    Croce, C.M.3
  • 94
    • 65249146132 scopus 로고    scopus 로고
    • The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim
    • 10.1053/j.gastro.2009.02.002, 2887605, 19422085
    • Kan T, Sato F, Ito T, Matsumura N, David S, Cheng Y, Agarwal R, Paun BC, Jin Z, Olaru AV, et al. The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim. Gastroenterology 2009, 136:1689-1700. 10.1053/j.gastro.2009.02.002, 2887605, 19422085.
    • (2009) Gastroenterology , vol.136 , pp. 1689-1700
    • Kan, T.1    Sato, F.2    Ito, T.3    Matsumura, N.4    David, S.5    Cheng, Y.6    Agarwal, R.7    Paun, B.C.8    Jin, Z.9    Olaru, A.V.10
  • 95
    • 77957869316 scopus 로고    scopus 로고
    • Suppression of p21 by c-Myc through members of miR-17 family at the post-transcriptional level
    • Wang Z, Liu M, Zhu H, Zhang W, He S, Hu C, Quan L, Bai J, Xu N. Suppression of p21 by c-Myc through members of miR-17 family at the post-transcriptional level. Int J Oncol 2010, 37:1315-1321.
    • (2010) Int J Oncol , vol.37 , pp. 1315-1321
    • Wang, Z.1    Liu, M.2    Zhu, H.3    Zhang, W.4    He, S.5    Hu, C.6    Quan, L.7    Bai, J.8    Xu, N.9
  • 96
    • 84862908319 scopus 로고    scopus 로고
    • MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer
    • Zhang H, Zuo Z, Lu X, Wang L, Wang H, Zhu Z. MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer. Oncol Rep 2012, 27:594-598.
    • (2012) Oncol Rep , vol.27 , pp. 594-598
    • Zhang, H.1    Zuo, Z.2    Lu, X.3    Wang, L.4    Wang, H.5    Zhu, Z.6
  • 97
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • 10.1038/onc.2010.457, 3021102, 20935678
    • Kumar M, Lu Z, Takwi AA, Chen W, Callander NS, Ramos KS, Young KH, Li Y. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene 2011, 30:843-853. 10.1038/onc.2010.457, 3021102, 20935678.
    • (2011) Oncogene , vol.30 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.3    Chen, W.4    Callander, N.S.5    Ramos, K.S.6    Young, K.H.7    Li, Y.8
  • 100
    • 70949104622 scopus 로고    scopus 로고
    • MiR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
    • 10.1016/j.ccr.2009.10.014, 2796583, 19962668
    • Garofalo M, Di Leva G, Romano G, Nuovo G, Suh SS, Ngankeu A, Taccioli C, Pichiorri F, Alder H, Secchiero P, et al. miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell 2009, 16:498-509. 10.1016/j.ccr.2009.10.014, 2796583, 19962668.
    • (2009) Cancer Cell , vol.16 , pp. 498-509
    • Garofalo, M.1    Di Leva, G.2    Romano, G.3    Nuovo, G.4    Suh, S.S.5    Ngankeu, A.6    Taccioli, C.7    Pichiorri, F.8    Alder, H.9    Secchiero, P.10
  • 101
    • 71849111080 scopus 로고    scopus 로고
    • Alterations in microRNA expression in stress-induced cellular senescence
    • 10.1016/j.mad.2009.09.002, 2795064, 19782699
    • Li G, Luna C, Qiu J, Epstein DL, Gonzalez P. Alterations in microRNA expression in stress-induced cellular senescence. Mech Ageing Dev 2009, 130:731-741. 10.1016/j.mad.2009.09.002, 2795064, 19782699.
    • (2009) Mech Ageing Dev , vol.130 , pp. 731-741
    • Li, G.1    Luna, C.2    Qiu, J.3    Epstein, D.L.4    Gonzalez, P.5
  • 104
    • 84867839436 scopus 로고    scopus 로고
    • MiR-335 promotes cell proliferation by directly targeting Rb1 in meningiomas
    • 10.1007/s11060-012-0951-z, 22886530
    • Shi L, Jiang D, Sun G, Wan Y, Zhang S, Zeng Y, Pan T, Wang Z. miR-335 promotes cell proliferation by directly targeting Rb1 in meningiomas. J Neurooncol 2012, 110:155-162. 10.1007/s11060-012-0951-z, 22886530.
    • (2012) J Neurooncol , vol.110 , pp. 155-162
    • Shi, L.1    Jiang, D.2    Sun, G.3    Wan, Y.4    Zhang, S.5    Zeng, Y.6    Pan, T.7    Wang, Z.8
  • 105
    • 84860473453 scopus 로고    scopus 로고
    • MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-beta signalling pathway
    • 10.1093/carcin/bgs114, 3334516, 22382496
    • Lynch J, Fay J, Meehan M, Bryan K, Watters KM, Murphy DM, Stallings RL. MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-beta signalling pathway. Carcinogenesis 2012, 33:976-985. 10.1093/carcin/bgs114, 3334516, 22382496.
    • (2012) Carcinogenesis , vol.33 , pp. 976-985
    • Lynch, J.1    Fay, J.2    Meehan, M.3    Bryan, K.4    Watters, K.M.5    Murphy, D.M.6    Stallings, R.L.7
  • 106
    • 77956285040 scopus 로고    scopus 로고
    • MiR-335 directly targets Rb1 (pRb/p105) in a proximal connection to p53-dependent stress response
    • 10.1158/0008-5472.CAN-10-0141, 20713524
    • Scarola M, Schoeftner S, Schneider C, Benetti R. miR-335 directly targets Rb1 (pRb/p105) in a proximal connection to p53-dependent stress response. Cancer Res 2010, 70:6925-6933. 10.1158/0008-5472.CAN-10-0141, 20713524.
    • (2010) Cancer Res , vol.70 , pp. 6925-6933
    • Scarola, M.1    Schoeftner, S.2    Schneider, C.3    Benetti, R.4
  • 107
    • 84855180543 scopus 로고    scopus 로고
    • MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development
    • 10.1002/ijc.25962, 21618216
    • Heyn H, Engelmann M, Schreek S, Ahrens P, Lehmann U, Kreipe H, Schlegelberger B, Beger C. MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development. Int J Cancer 2011, 129:2797-2806. 10.1002/ijc.25962, 21618216.
    • (2011) Int J Cancer , vol.129 , pp. 2797-2806
    • Heyn, H.1    Engelmann, M.2    Schreek, S.3    Ahrens, P.4    Lehmann, U.5    Kreipe, H.6    Schlegelberger, B.7    Beger, C.8
  • 108
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • 10.1093/biostatistics/4.2.249, 12925520
    • Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003, 4:249-264. 10.1093/biostatistics/4.2.249, 12925520.
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1    Hobbs, B.2    Collin, F.3    Beazer-Barclay, Y.D.4    Antonellis, K.J.5    Scherf, U.6    Speed, T.P.7
  • 109
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • 10.1073/pnas.091062498, 33173, 11309499
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 2001, 98:5116-5121. 10.1073/pnas.091062498, 33173, 11309499.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 112
    • 84864494098 scopus 로고    scopus 로고
    • GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics
    • 10.1093/nar/gks402, 3394297, 22573175
    • Tabas-Madrid D, Nogales-Cadenas R, Pascual-Montano A. GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics. Nucleic Acids Res 2012, 40:W478-W483. 10.1093/nar/gks402, 3394297, 22573175.
    • (2012) Nucleic Acids Res , vol.40
    • Tabas-Madrid, D.1    Nogales-Cadenas, R.2    Pascual-Montano, A.3
  • 113
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • 300
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc 1995, 57:289. 300.
    • (1995) J Royal Stat Soc , vol.57 , pp. 289
    • Benjamini, Y.1    Hochberg, Y.2
  • 115
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • 10.1093/nar/29.9.e45, 55695, 11328886
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29:e45. 10.1093/nar/29.9.e45, 55695, 11328886.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.