-
1
-
-
35948946514
-
FoxO transcription factors suppress Mycdriven lymphomagenesis via direct activation of Arf
-
Bouchard C, Lee S, Paulus-Hock V, Loddenkemper C, Eilers M, Schmitt CA. (2007). FoxO transcription factors suppress Mycdriven lymphomagenesis via direct activation of Arf. Genes Dev 21: 2775-2787.
-
(2007)
Genes Dev
, vol.21
, pp. 2775-2787
-
-
Bouchard, C.1
Lee, S.2
Paulus-Hock, V.3
Loddenkemper, C.4
Eilers, M.5
Schmitt, C.A.6
-
2
-
-
22844445705
-
Temporal dissection of p53 function in vitro and in vivo
-
Christophorou MA, Martin-Zanca D, Soucek L, Lawlor ER, Brown-Swigart L, Verschuren EW, Evan GI. (2005). Temporal dissection of p53 function in vitro and in vivo. Nat Genet 37: 718-726.
-
(2005)
Nat Genet
, vol.37
, pp. 718-726
-
-
Christophorou, M.A.1
Martin-Zanca, D.2
Soucek, L.3
Lawlor, E.R.4
Brown-Swigart, L.5
Verschuren, E.W.6
Evan, G.I.7
-
3
-
-
80052955256
-
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
-
Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM, Kastritis E, Gilpatrick T, Paranal RM, Qi J, et al. (2011). BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146: 904-917.
-
(2011)
Cell
, vol.146
, pp. 904-917
-
-
Delmore, J.E.1
Issa, G.C.2
Lemieux, M.E.3
Rahl, P.B.4
Shi, J.5
Jacobs, H.M.6
Kastritis, E.7
Gilpatrick, T.8
Paranal, R.M.9
Qi, J.10
-
4
-
-
79959989346
-
Peroxisome proliferator activated receptor a ligands as anti-cancer drugs targeting mitochondrial metabolism
-
PMID: 21133850
-
Grabacka M, Pierzchalska M, Reiss K. (2010). Peroxisome proliferator activated receptor a ligands as anti-cancer drugs targeting mitochondrial metabolism. Curr Pharm Biotechnol PMID: 21133850.
-
(2010)
Curr Pharm Biotechnol
-
-
Grabacka, M.1
Pierzchalska, M.2
Reiss, K.3
-
5
-
-
0035893252
-
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
-
Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA. (2001). Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes & Dev 15: 3243-3248.
-
(2001)
Genes & Dev
, vol.15
, pp. 3243-3248
-
-
Jackson, E.L.1
Willis, N.2
Mercer, K.3
Bronson, R.T.4
Crowley, D.5
Montoya, R.6
Jacks, T.7
Tuveson, D.A.8
-
6
-
-
28544432790
-
The differential effects of mutant p53 alleles on advanced murine lung cancer
-
Jackson EL, Olive KP, Tuveson DA, Bronson R, Crowley D, Brown M, Jacks T. (2005). The differential effects of mutant p53 alleles on advanced murine lung cancer. Cancer Res 65: 10280-10288.
-
(2005)
Cancer Res
, vol.65
, pp. 10280-10288
-
-
Jackson, E.L.1
Olive, K.P.2
Tuveson, D.A.3
Bronson, R.4
Crowley, D.5
Brown, M.6
Jacks, T.7
-
7
-
-
84861563268
-
Cancer incidence in patients with polyglutamine diseases: A population-based study in Sweden
-
Ji J, Sundquist K, Sundquist J. (2012). Cancer incidence in patients with polyglutamine diseases: A population-based study in Sweden. Lancet Oncol 13: 642-648.
-
(2012)
Lancet Oncol
, vol.13
, pp. 642-648
-
-
Ji, J.1
Sundquist, K.2
Sundquist, J.3
-
8
-
-
78649492693
-
Selective activation of p53-mediated tumour suppression in high-grade tumours
-
Junttila MR, Karnezis AN, Garcia D, Madriles F, Kortlever RM, Rostker F, Brown Swigart L, Pham DM, Seo Y, Evan GI, et al. (2010). Selective activation of p53-mediated tumour suppression in high-grade tumours. Nature 468: 567-571.
-
(2010)
Nature
, vol.468
, pp. 567-571
-
-
Junttila, M.R.1
Karnezis, A.N.2
Garcia, D.3
Madriles, F.4
Kortlever, R.M.5
Rostker, F.6
Brown Swigart, L.7
Pham, D.M.8
Seo, Y.9
Evan, G.I.10
-
9
-
-
33746394560
-
Mouse models of human non-small-cell lung cancer: Raising the bar
-
Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, et al. (2005). Mouse models of human non-small-cell lung cancer: Raising the bar. Cold Spring Harb Symp Quant Biol 70: 241-250.
-
(2005)
Cold Spring Harb Symp Quant Biol
, vol.70
, pp. 241-250
-
-
Kim, C.F.1
Jackson, E.L.2
Kirsch, D.G.3
Grimm, J.4
Shaw, A.T.5
Lane, K.6
Kissil, J.7
Olive, K.P.8
Sweet-Cordero, A.9
Weissleder, R.10
-
10
-
-
77952576753
-
The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy
-
Larsson LG, Henriksson MA. (2010). The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy. Exp Cell Res 316: 1429-1437.
-
(2010)
Exp Cell Res
, vol.316
, pp. 1429-1437
-
-
Larsson, L.G.1
Henriksson, M.A.2
-
11
-
-
55949120110
-
Activation of Nrf2-antioxidant signaling attenuates NFkBinflammatory response and elicits apoptosis
-
Li W, Khor TO, Xu C, Shen G, Jeong WS, Yu S, Kong AN. (2008). Activation of Nrf2-antioxidant signaling attenuates NFkBinflammatory response and elicits apoptosis. Biochem Pharmacol 76: 1485-1489.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 1485-1489
-
-
Li, W.1
Khor, T.O.2
Xu, C.3
Shen, G.4
Jeong, W.S.5
Yu, S.6
Kong, A.N.7
-
12
-
-
0033556344
-
Analysis of a very large trinucleotide repeat in a patient with juvenile Huntington's disease
-
Nance MA, Mathias-Hagen V, Breningstall G, Wick MJ, McGlennen RC. (1999). Analysis of a very large trinucleotide repeat in a patient with juvenile Huntington's disease. Neurology 52: 392-394.
-
(1999)
Neurology
, vol.52
, pp. 392-394
-
-
Nance, M.A.1
Mathias-Hagen, V.2
Breningstall, G.3
Wick, M.J.4
McGlennen, R.C.5
-
13
-
-
77950923924
-
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
-
Oliver TG, Mercer KL, Sayles LC, Burke JR, Mendus D, Lovejoy KS, Cheng MH, Subramanian A, Mu D, Powers S, et al. (2010). Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes Dev 24: 837-852.
-
(2010)
Genes Dev
, vol.24
, pp. 837-852
-
-
Oliver, T.G.1
Mercer, K.L.2
Sayles, L.C.3
Burke, J.R.4
Mendus, D.5
Lovejoy, K.S.6
Cheng, M.H.7
Subramanian, A.8
Mu, D.9
Powers, S.10
-
14
-
-
84864634079
-
Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state
-
Rounbehler RJ, Fallahi M, Yang C, Steeves MA, Li W, Doherty JR, Schaub FX, Sanduja S, Dixon DA, Blackshear PJ, et al. (2012). Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state. Cell 150: 563-574.
-
(2012)
Cell
, vol.150
, pp. 563-574
-
-
Rounbehler, R.J.1
Fallahi, M.2
Yang, C.3
Steeves, M.A.4
Li, W.5
Doherty, J.R.6
Schaub, F.X.7
Sanduja, S.8
Dixon, D.A.9
Blackshear, P.J.10
-
15
-
-
79960623998
-
The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy
-
Savino M, Annibali D, Carucci N, Favuzzi E, Cole MD, Evan GI, Soucek L, Nasi S. (2011). The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy. PLoS ONE 6: e22284.
-
(2011)
PLoS ONE
, vol.6
-
-
Savino, M.1
Annibali, D.2
Carucci, N.3
Favuzzi, E.4
Cole, M.D.5
Evan, G.I.6
Soucek, L.7
Nasi, S.8
-
16
-
-
77953262592
-
Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models
-
Singh M, Lima A, Molina R, Hamilton P, Clermont AC, Devasthali V, Thompson JD, Cheng JH, Bou Reslan H, Ho CC, et al. (2010). Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models. Nat Biotechnol 28: 585-593.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 585-593
-
-
Singh, M.1
Lima, A.2
Molina, R.3
Hamilton, P.4
Clermont, A.C.5
Devasthali, V.6
Thompson, J.D.7
Cheng, J.H.8
Bou Reslan, H.9
Ho, C.C.10
-
17
-
-
79955403911
-
Endogenous Myc maintains the tumor microenvironment
-
Sodir NM, Swigart LB, Karnezis AN, Hanahan D, Evan GI, Soucek L. (2011). Endogenous Myc maintains the tumor microenvironment. Genes Dev 25: 907-916.
-
(2011)
Genes Dev
, vol.25
, pp. 907-916
-
-
Sodir, N.M.1
Swigart, L.B.2
Karnezis, A.N.3
Hanahan, D.4
Evan, G.I.5
Soucek, L.6
-
18
-
-
0032511987
-
Design and properties of a Myc derivative that efficiently homodimerizes
-
Soucek L, Helmer-Citterich M, Sacco A, Jucker R, Cesareni G, Nasi S. (1998). Design and properties of a Myc derivative that efficiently homodimerizes. Oncogene 17: 2463-2472.
-
(1998)
Oncogene
, vol.17
, pp. 2463-2472
-
-
Soucek, L.1
Helmer-Citterich, M.2
Sacco, A.3
Jucker, R.4
Cesareni, G.5
Nasi, S.6
-
19
-
-
0037096903
-
Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis
-
Soucek L, Jucker R, Panacchia L, Ricordy R, Tato F, Nasi S. (2002). Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis. Cancer Res 62: 3507-3510.
-
(2002)
Cancer Res
, vol.62
, pp. 3507-3510
-
-
Soucek, L.1
Jucker, R.2
Panacchia, L.3
Ricordy, R.4
Tato, F.5
Nasi, S.6
-
20
-
-
4544221109
-
Omomyc expression in skin prevents Myc-induced papillomatosis
-
Soucek L, Nasi S, Evan GI. (2004). Omomyc expression in skin prevents Myc-induced papillomatosis. Cell Death Differ 11: 1038-1045.
-
(2004)
Cell Death Differ
, vol.11
, pp. 1038-1045
-
-
Soucek, L.1
Nasi, S.2
Evan, G.I.3
-
21
-
-
53349103292
-
Modelling Myc inhibition as a cancer therapy
-
Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, Karnezis AN, Swigart LB, Nasi S, Evan GI. (2008). Modelling Myc inhibition as a cancer therapy. Nature 455: 679-683.
-
(2008)
Nature
, vol.455
, pp. 679-683
-
-
Soucek, L.1
Whitfield, J.2
Martins, C.P.3
Finch, A.J.4
Murphy, D.J.5
Sodir, N.M.6
Karnezis, A.N.7
Swigart, L.B.8
Nasi, S.9
Evan, G.I.10
-
22
-
-
11244258643
-
An oncogenic KRAS2 expression signature identified by crossspecies gene-expression analysis
-
Sweet-Cordero A, Mukherjee S, Subramanian A, You H, Roix JJ, Ladd-Acosta C, Mesirov J, Golub TR, Jacks T. (2005). An oncogenic KRAS2 expression signature identified by crossspecies gene-expression analysis. Nat Genet 37: 48-55.
-
(2005)
Nat Genet
, vol.37
, pp. 48-55
-
-
Sweet-Cordero, A.1
Mukherjee, S.2
Subramanian, A.3
You, H.4
Roix, J.J.5
Ladd-Acosta, C.6
Mesirov, J.7
Golub, T.R.8
Jacks, T.9
-
24
-
-
11144356354
-
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects
-
Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, et al. (2004). Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects. Cancer Cell 5: 375-387.
-
(2004)
Cancer Cell
, vol.5
, pp. 375-387
-
-
Tuveson, D.A.1
Shaw, A.T.2
Willis, N.A.3
Silver, D.P.4
Jackson, E.L.5
Chang, S.6
Mercer, K.L.7
Grochow, R.8
Hock, H.9
Crowley, D.10
-
25
-
-
80055000824
-
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
-
Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, et al. (2011). RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 478: 524-528.
-
(2011)
Nature
, vol.478
, pp. 524-528
-
-
Zuber, J.1
Shi, J.2
Wang, E.3
Rappaport, A.R.4
Herrmann, H.5
Sison, E.A.6
Magoon, D.7
Qi, J.8
Blatt, K.9
Wunderlich, M.10
|