MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development

International Journal of Cancer

Volumn 129, Issue 12, 2011, Pages 2797-2806

  Heyn, Holger ^a   Engelmann, Maria ^a   Schreek, Sabine ^a   Ahrens, Philipp ^a   Lehmann, Ulrich ^a   Kreipe, Hans ^a   Schlegelberger, Brigitte ^a   Beger, Carmela ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

BRCA1; breast cancer development; microRNA; regulation

Indexed keywords

BRCA1 PROTEIN; ESTROGEN RECEPTOR ALPHA; INHIBITOR OF DIFFERENTIATION PROTEIN; LUCIFERASE; MICRORNA; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; PROTEIN ID4; PROTEIN MIR 335; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; ESTROGEN; MIRN335 MICRORNA, HUMAN;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FEEDBACK SYSTEM; GENE OVEREXPRESSION; GENE REGULATORY NETWORK; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; AGED; BREAST TUMOR; CELL SURVIVAL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

AGED; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; HUMANS; MICRORNAS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84855180543     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25962     Document Type: Article

References (37)

1. Madigan MP, Ziegler RG, Benichou J, Byrne C, Hoover RN,. Proportion of breast cancer cases in the United States explained by well-established risk factors. J Natl Cancer Inst 1995; 87: 1681-5.
2. Easton DF, Ford D, Bishop DT,. Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast cancer linkage consortium. Am J Hum Genet 1995; 56: 265-71.
3. Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S, Bennett LM, Haugen-Strano A, Swensen J, Miki Y,. BRCA1 mutations in primary breast and ovarian carcinomas. Science 1994; 266: 120-2. (Pubitemid 24345332)
4. Thompson ME, Jensen RA, Obermiller PS, Page DL, Holt JL,. Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat Genet 1995; 9: 444-50.
5. Jeffy BD, Hockings JK, Kemp MQ, Morgan SS, Hager JA, Beliakoff J, Whitesell LJ, Bowden GT, Romagnolo DF,. An estrogen receptor-alpha/p300 complex activates the BRCA-1 promoter at an AP-1 site that binds Jun/Fos transcription factors: repressive effects of p53 on BRCA-1 transcription. Neoplasia 2005; 7: 873-82.
6. Hockings JK, Thorne PA, Kemp MQ, Morgan SS, Selmin O, Romagnolo DF,. The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen. Cancer Res 2006; 66: 2224-32.
7. Maor S, Papa MZ, Yarden RI, Friedman E, Lerenthal Y, Lee SW, Mayer D, Werner H,. Insulin-like growth factor-I controls BRCA1 gene expression through activation of transcription factor Sp1. Horm Metab Res 2007; 39: 179-85. (Pubitemid 46580615)
8. Hockings JK, Degner SC, Morgan SS, Kemp MQ, Romagnolo DF,. Involvement of a specificity proteins-binding element in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene. Breast Cancer Res 2008; 10: R29.
9. Beger C, Pierce LN, Kruger M, Marcusson EG, Robbins JM, Welcsh P, Welch PJ, Welte K, King MC, Barber JR, Wong-Staal F,. Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach. Proc Natl Acad Sci USA 2001; 98: 130-5. (Pubitemid 32095875)
10. Bushati N, Cohen SM,. microRNA functions. Annu Rev Cell Dev Biol 2007; 23: 175-205.
11. Esquela-Kerscher A, Slack FJ,. Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 2006; 6: 259-69.
12. Johnson CD, Esquela-Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown D, et al. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res 2007; 67: 7713-22. (Pubitemid 47281364)
13. Iorio MV, Ferracin M, Liu C, Veronese A, Spizzo R, Sabbioni S, Magri E, Pedriali M, Fabbri M, Campiglio M, Ménard S, Palazzo JP, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65: 7065-70. (Pubitemid 41161233)
14. Blenkiron C, Goldstein LD, Thorne NP, Spiteri I, Chin S, Dunning MJ, Barbosa-Morais NL, Teschendorff AE, Green AR, Ellis IO, Tavaré S, Caldas C, et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol 2007; 8: R214.
15. Liu W, Yeh S, Lu C, Yu S, Chen H, Lin C, Chen D, Chen P,. MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells. Gastroenterology 2009; 136: 683-93.
16. Zhao J, Lin J, Yang H, Kong W, He L, Ma X, Coppola D, Cheng JQ,. MicroRNA-221/222 negatively regulates estrogen receptor{alpha} and is associated with tamoxifen resistance in breast cancer. J Biol Chem 2008; 283: 31079-86.
17. Adams BD, Furneaux H, White BA,. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 2007; 21: 1132-47. (Pubitemid 46984764)
18. Kondo N, Toyama T, Sugiura H, Fujii Y, Yamashita H,. miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. Cancer Res 2008; 68: 5004-8.
19. Pandey DP, Picard D,. miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor {alpha} mRNA. Mol Cell Biol 2009; 29: 3783-90.
20. Sun M, Estrov Z, Ji Y, Coombes KR, Harris DH, Kurzrock R,. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol Cancer Ther 2008; 7: 464-73. (Pubitemid 351482129)
21. Tavazoie SF, Alarcõn C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massagué J,. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008; 451: 147-52.
22. Sorrentino A, Liu C, Addario A, Peschle C, Scambia G, Ferlini C,. Role of microRNAs in drug-resistant ovarian cancer cells. Gynecol Oncol 2008; 111: 478-86.
23. Chakraborty AK, Liang K, DiGiovanna MP,. Co-targeting insulin-like growth factor I receptor and HER2: dramatic effects of HER2 inhibitors on nonoverexpressing breast cancer. Cancer Res 2008; 68: 1538-45. (Pubitemid 351346863)
24. Chakraborty AK, Welsh A, Digiovanna MP,. Co-targeting the insulin-like growth factor I receptor enhances growth-inhibitory and pro-apoptotic effects of anti-estrogens in human breast cancer cell lines. Breast Cancer Res Treat 2010; 120: 327-35.
25. Pramoonjago P, Baras AS, Moskaluk CA,. Knockdown of Sox4 expression by RNAi induces apoptosis in ACC3 cells. Oncogene 2006; 25: 5626-39. (Pubitemid 44387618)
26. Sathyan P, Golden HB, Miranda RC,. Competing interactions between microRNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. J Neurosci 2007; 27: 8546-57. (Pubitemid 47254255)
27. Purow BW, Haque RM, Noel MW, Su Q, Burdick MJ, Lee J, Sundaresan T, Pastorino S, Park JK, Mikolaenko I, Maric D, Eberhart CG, et al. Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Res 2005; 65: 2353-63. (Pubitemid 40490146)
28. Shan L, Yu M, Qiu C, Snyderwine EG,. Id4 regulates mammary epithelial cell growth and differentiation and is overexpressed in rat mammary gland carcinomas. Am J Pathol 2003; 163: 2495-502. (Pubitemid 37466490)
29. Rubini M, Hongo A, D'Ambrosio C, Baserga R,. The IGF-I receptor in mitogenesis and transformation of mouse embryo cells: role of receptor number. Exp Cell Res 1997, 230: 284-92. (Pubitemid 27190648)
30. Price JE, Polyzos A, Zhang RD, Daniels LM,. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 1990; 50: 717-21. (Pubitemid 20054204)
31. Zannetti A, Del Vecchio S, Carriero MV, Fonti R, Franco P, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M,. Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma. Cancer Res 2000; 60: 1546-51. (Pubitemid 30183423)
32. Roldán G, Delgado L, Musé IM,. Tumoral expression of BRCA1, estrogen receptor alpha and ID4 protein in patients with sporadic breast cancer. Cancer Biol Ther 2006; 5: 505-10. (Pubitemid 43765285)
33. Turner NC, Reis-Filho JS, Russell AM, Springdall RJ, Ryder K, Steele D, Savage K, Gillett CE, Schmitt FC, Ashworth A, Tutt AN,. BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene 2007; 26: 2126-32. (Pubitemid 46514749)
34. Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos MR, Pestell RG, Yuan F, Auborn KJ, Goldberg ID, Rosen EM,. BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science 1999; 284: 1354-6. (Pubitemid 29289660)
35. Klinge CM,. Estrogen regulation of microRNA expression. Curr Genomics 2009; 10: 169-83.
36. Monteys AM, Spengler RM, Wan J, Tecedor L, Lennox KA, Xing Y, Davidson BL,. Structure and activity of putative intronic miRNA promoters. RNA 2010; 16: 495-505.
37. Ottaviano YL, Issa JP, Parl FF, Smith HS, Baylin SB, Davidson NE,. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res 1994; 54: 2552-55. (Pubitemid 24173735)