-
1
-
-
0035794637
-
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
-
Jordan, A.; Defechereux, P.; Verdin, E. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J. 2001, 20, 1726-1738
-
(2001)
EMBO J
, vol.20
, pp. 1726-1738
-
-
Jordan, A.1
Defechereux, P.2
Verdin, E.3
-
2
-
-
0037446948
-
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
-
Jordan, A.; Bisgrove, D.; Verdin, E. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. EMBO J. 2003, 22, 1868-1877
-
(2003)
EMBO J
, vol.22
, pp. 1868-1877
-
-
Jordan, A.1
Bisgrove, D.2
Verdin, E.3
-
3
-
-
21044451712
-
Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription
-
Lewinski, M. K.; Bisgrove, D.; Shinn, P.; Chen, H.; Hoffmann, C.; Hannenhalli, S.; Verdin, E.; Berry, C. C.; Ecker, J. R.; Bushman, F. D. Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription. J. Virol. 2005, 79, 6610-6619
-
(2005)
J. Virol.
, vol.79
, pp. 6610-6619
-
-
Lewinski, M.K.1
Bisgrove, D.2
Shinn, P.3
Chen, H.4
Hoffmann, C.5
Hannenhalli, S.6
Verdin, E.7
Berry, C.C.8
Ecker, J.R.9
Bushman, F.D.10
-
4
-
-
0004131381
-
-
Cold SpringHarborLaboratoryPress,ColdSpringHarbor,NY
-
Coffin, J. M.; Hughes, S.; Varmus, H. E. Retroviruses. Cold SpringHarborLaboratoryPress,ColdSpringHarbor,NY, 1997
-
(1997)
Retroviruses
-
-
Coffin, J.M.1
Hughes, S.2
Varmus, H.E.3
-
5
-
-
0025968854
-
Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex
-
Farnet, C.M.; Haseltine,W. A. Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex. J. Virol. 1991, 65, 1910-1915
-
(1991)
J. Virol.
, vol.65
, pp. 1910-1915
-
-
Farnet, C.M.1
Haseltine, W.A.2
-
6
-
-
0031004162
-
HIV-1 cDNA integration: Requirement of HMG I(Y) protein for function of preintegration complexes in vitro
-
Farnet, C. M.; Bushman, F. D. HIV-1 cDNA integration: Requirement of HMG I(Y) protein for function of preintegration complexes in vitro. Cell 1997, 88, 483-492
-
(1997)
Cell
, vol.88
, pp. 483-492
-
-
Farnet, C.M.1
Bushman, F.D.2
-
7
-
-
0030972160
-
Human immunodeficiency virus type 1 preintegration complexes: Studies of organization and composition
-
Miller, M. D.; Farnet, C. M.; Bushman, F. D. Human immunodeficiency virus type 1 preintegration complexes: Studies of organization and composition. J. Virol. 1997, 71, 5382-5390
-
(1997)
J. Virol.
, vol.71
, pp. 5382-5390
-
-
Miller, M.D.1
Farnet, C.M.2
Bushman, F.D.3
-
8
-
-
0030740070
-
Human immunodeficiency virus type 1 nucleocapsid protein specifically stimulates Mg2{thorn} -dependent DNA integration in vitro
-
Carteau, S.; Batson, S. C.; Poljak, L.; Mouscadet, J. F.; de Rocquigny, H.; Darlix, J. L.; Roques, B. P.; Kas, E.; Auclair, C. Human immunodeficiency virus type 1 nucleocapsid protein specifically stimulates Mg2{thorn} -dependent DNA integration in vitro. J. Virol. 1997, 71, 6225-6229
-
(1997)
J. Virol.
, vol.71
, pp. 6225-6229
-
-
Carteau, S.1
Batson, S.C.2
Poljak, L.3
Mouscadet, J.F.4
de Rocquigny, H.5
Darlix, J.L.6
Roques, B.P.7
Kas, E.8
Auclair, C.9
-
9
-
-
0032433829
-
The barrier-to-autointegration protein is a host factor for HIV type 1 integration
-
Chen, H.; Engelman, A. The barrier-to-autointegration protein is a host factor for HIV type 1 integration. Proc. Natl. Acad. Sci. USA 1998, 95, 15270-15274
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15270-15274
-
-
Chen, H.1
Engelman, A.2
-
10
-
-
0031936603
-
Modulation of activity of Moloney murine leukemia virus preintegration complexes by host factors in vitro
-
Li, L.; Farnet, C. M.; Anderson, W. F.; Bushman, F. D. Modulation of activity of Moloney murine leukemia virus preintegration complexes by host factors in vitro. J. Virol. 1998, 72, 2125-2131
-
(1998)
J. Virol.
, vol.72
, pp. 2125-2131
-
-
Li, L.1
Farnet, C.M.2
Anderson, W.F.3
Bushman, F.D.4
-
11
-
-
0032776165
-
Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: Stimulation by the viral nucleocapsid protein
-
Carteau, S.; Gorelick, R. J.; Bushman, F. D. Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: Stimulation by the viral nucleocapsid protein. J. Virol. 1999, 73, 6670-6679
-
(1999)
J. Virol.
, vol.73
, pp. 6670-6679
-
-
Carteau, S.1
Gorelick, R.J.2
Bushman, F.D.3
-
12
-
-
0032616706
-
Host proteins in retroviral cDNA integration
-
Bushman, F. D. Host proteins in retroviral cDNA integration. Adv. Virus Res. 1999, 52, 301-317
-
(1999)
Adv. Virus Res.
, vol.52
, pp. 301-317
-
-
Bushman, F.D.1
-
14
-
-
0034467084
-
Retroviral cDNA integration: Stimulation by HMG I family proteins
-
Li, L.; Yoder, K.; Hansen, M. S.; Olvera, J.; Miller, M. D.; Bushman, F. D. Retroviral cDNA integration: Stimulation by HMG I family proteins. J. Virol. 2000, 74, 10965-10974
-
(2000)
J. Virol.
, vol.74
, pp. 10965-10974
-
-
Li, L.1
Yoder, K.2
Hansen, M.S.3
Olvera, J.4
Miller, M.D.5
Bushman, F.D.6
-
15
-
-
0034671508
-
Both the structure and DNA binding function of the barrier-to-autointegration factor contribute to reconstitution of HIV type 1 integration in vitro
-
Harris, D.; Engelman, A. Both the structure and DNA binding function of the barrier-to-autointegration factor contribute to reconstitution of HIV type 1 integration in vitro. J. Biol. Chem. 2000, 275, 39671-39677
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39671-39677
-
-
Harris, D.1
Engelman, A.2
-
16
-
-
0036209708
-
Integration site selection by lentiviruses: Biology and possible control
-
Bushman, F. D. Integration site selection by lentiviruses: Biology and possible control. Curr. Top. Microbiol. Immunol. 2002, 261, 165-177
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.261
, pp. 165-177
-
-
Bushman, F.D.1
-
17
-
-
0037227942
-
Cofactors for human immunodeficiency virus type 1 cDNA integration in vitro
-
Gao, K.; Gorelick, R. J.; Johnson, D. G.; Bushman, F. Cofactors for human immunodeficiency virus type 1 cDNA integration in vitro. J. Virol. 2003, 77, 1598-1603
-
(2003)
J. Virol.
, vol.77
, pp. 1598-1603
-
-
Gao, K.1
Gorelick, R.J.2
Johnson, D.G.3
Bushman, F.4
-
18
-
-
0346036088
-
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
-
Cherepanov, P.; Maertens, G.; Proost, P.; Devreese, B.; Van Beeumen, J.; Engelborghs, Y.; De Clercq, E.; Debyser, Z. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. J. Biol. Chem. 2003, 278, 372-381
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 372-381
-
-
Cherepanov, P.1
Maertens, G.2
Proost, P.3
Devreese, B.4
Van Beeumen, J.5
Engelborghs, Y.6
De Clercq, E.7
Debyser, Z.8
-
19
-
-
0042164434
-
The roles of cellular factors in retroviral integration
-
Engelman, A. The roles of cellular factors in retroviral integration. Curr. Top. Microbiol. Immunol. 2003, 281, 209-238
-
(2003)
Curr. Top. Microbiol. Immunol.
, vol.281
, pp. 209-238
-
-
Engelman, A.1
-
20
-
-
2342660750
-
Integration site selection by retroviruses
-
Cereseto, A.; Giacca, M. Integration site selection by retroviruses. AIDS Rev. 2004, 6, 13-21
-
(2004)
AIDS Rev
, vol.6
, pp. 13-21
-
-
Cereseto, A.1
Giacca, M.2
-
21
-
-
8644231282
-
Human cell proteins and human immunodeficiency virus DNA integration
-
Turlure, F.; Devroe, E.; Silver, P. A.; Engelman, A. Human cell proteins and human immunodeficiency virus DNA integration. Front. Biosci. 2004, 9, 3187-3208
-
(2004)
Front. Biosci.
, vol.9
, pp. 3187-3208
-
-
Turlure, F.1
Devroe, E.2
Silver, P.A.3
Engelman, A.4
-
22
-
-
28144462457
-
Genome-wide analysis of retroviral DNA integration
-
Bushman, F.; Lewinski, M.; Ciuffi, A.; Barr, S.; Leipzig, J.; Hannenhalli, S.; Hoffmann, C. Genome-wide analysis of retroviral DNA integration. Nat. Rev. Microbiol. 2005. 3, 848-858
-
(2005)
Nat. Rev. Microbiol.
, vol.3
, pp. 848-858
-
-
Bushman, F.1
Lewinski, M.2
Ciuffi, A.3
Barr, S.4
Leipzig, J.5
Hannenhalli, S.6
Hoffmann, C.7
-
23
-
-
18744371922
-
HIV-1 integration: An interplay between HIV-1 integrase, cellular and viral proteins
-
Van Maele, B.; Debyser, Z. HIV-1 integration: An interplay between HIV-1 integrase, cellular and viral proteins. AIDS Rev. 2005, 7, 26-43
-
(2005)
AIDS Rev
, vol.7
, pp. 26-43
-
-
Van Maele, B.1
Debyser, Z.2
-
24
-
-
33644831457
-
Biochemical and genetic analyses of integraseinteracting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication
-
Vandegraaff, N.; Devroe, E.; Turlure, F.; Silver, P. A.; Engelman, A. Biochemical and genetic analyses of integraseinteracting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication. Virology 2006, 346, 415-426
-
(2006)
Virology
, vol.346
, pp. 415-426
-
-
Vandegraaff, N.1
Devroe, E.2
Turlure, F.3
Silver, P.A.4
Engelman, A.5
-
25
-
-
33745745419
-
RetroviralDNAintegration:HIVand the role of LEDGF/p75
-
Ciuffi, A.;Bushman,F.D. RetroviralDNAintegration:HIVand the role of LEDGF/p75. Trends Genet. 2006, 22, 388-395
-
(2006)
Trends Genet
, vol.22
, pp. 388-395
-
-
Ciuffi, A.1
Bushman, F.D.2
-
26
-
-
32344452179
-
Cellular co-factors of HIV-1 integration
-
Van Maele, B.; Busschots, K.; Vandekerckhove, L.; Christ, F.; Debyser, Z. Cellular co-factors of HIV-1 integration. Trends Biochem. Sci. 2006, 31, 98-105
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 98-105
-
-
Van Maele, B.1
Busschots, K.2
Vandekerckhove, L.3
Christ, F.4
Debyser, Z.5
-
27
-
-
33947379083
-
Host factors exploited by retroviruses
-
Goff, S. P. Host factors exploited by retroviruses. Nat. Rev. Microbiol. 2007, 5, 253-263
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 253-263
-
-
Goff, S.P.1
-
28
-
-
34748852513
-
Blocking interactions between HIV-1 integrase and cellular cofactors: An emerging anti-retroviral strategy
-
Al-Mawsawi, L. Q.; Neamati, N. Blocking interactions between HIV-1 integrase and cellular cofactors: An emerging anti-retroviral strategy. Trends Pharmacol. Sci. 2007, 28, 526-535
-
(2007)
Trends Pharmacol. Sci.
, vol.28
, pp. 526-535
-
-
Al-Mawsawi, L.Q.1
Neamati, N.2
-
29
-
-
0026330796
-
HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
-
Engelman, A.; Mizuuchi, K.; Craigie, R. HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer. Cell 1991, 67, 1211-1221
-
(1991)
Cell
, vol.67
, pp. 1211-1221
-
-
Engelman, A.1
Mizuuchi, K.2
Craigie, R.3
-
30
-
-
0034468560
-
Repair of gaps in retroviral DNA integration intermediates
-
Yoder, K. E.; Bushman, F. D. Repair of gaps in retroviral DNA integration intermediates. J. Virol. 2000, 74, 11191-11200
-
(2000)
J. Virol.
, vol.74
, pp. 11191-11200
-
-
Yoder, K.E.1
Bushman, F.D.2
-
32
-
-
0025133394
-
Retroviral DNA integration directed by HIV integration protein in vitro
-
Bushman, F. D.; Fujiwara, T.; Craigie, R. Retroviral DNA integration directed by HIV integration protein in vitro. Science 1990, 249, 1555-1558
-
(1990)
Science
, vol.249
, pp. 1555-1558
-
-
Bushman, F.D.1
Fujiwara, T.2
Craigie, R.3
-
33
-
-
0025031786
-
The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro
-
Craigie, R.; Fujiwara, T.; Bushman, F. The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro. Cell 1990, 62, 829-837
-
(1990)
Cell
, vol.62
, pp. 829-837
-
-
Craigie, R.1
Fujiwara, T.2
Bushman, F.3
-
34
-
-
0025011051
-
The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro
-
Katz, R. A.; Merkel, G.; Kulkosky, J.; Leis, J.; Skalka, A. M. The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro. Cell 1990, 63, 87-95
-
(1990)
Cell
, vol.63
, pp. 87-95
-
-
Katz, R.A.1
Merkel, G.2
Kulkosky, J.3
Leis, J.4
Skalka, A.M.5
-
35
-
-
0026034790
-
Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA
-
Bushman, F. D.; Craigie, R. Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA. Proc. Natl. Acad. Sci. USA 1991, 88, 1339-1343
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1339-1343
-
-
Bushman, F.D.1
Craigie, R.2
-
36
-
-
0028237180
-
In vitro activities of purified visna virus integrase
-
Katzman, M.; Sudol, M. In vitro activities of purified visna virus integrase. J. Virol. 1994, 68, 3558-3569
-
(1994)
J. Virol.
, vol.68
, pp. 3558-3569
-
-
Katzman, M.1
Sudol, M.2
-
37
-
-
0031434606
-
Molecular mechanisms in retrovirus DNA integration
-
Asante-Appiah, E.; Skalka, A. M. Molecular mechanisms in retrovirus DNA integration. Antiviral Res. 1997, 36, 139-156
-
(1997)
Antiviral Res
, vol.36
, pp. 139-156
-
-
Asante-Appiah, E.1
Skalka, A.M.2
-
38
-
-
0026713302
-
Simian virus 40 minichromosomes as targets for retroviral integration in vivo
-
Pryciak, P. M.; Muller, H. P.; Varmus, H. E. Simian virus 40 minichromosomes as targets for retroviral integration in vivo. Proc. Natl. Acad. Sci. USA 1992, 89, 9237-9241
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9237-9241
-
-
Pryciak, P.M.1
Muller, H.P.2
Varmus, H.E.3
-
39
-
-
0026567862
-
Retroviral integration into minichromosomes in vitro
-
Pryciak, P. M.; Sil, A.; Varmus, H. E. Retroviral integration into minichromosomes in vitro. EMBO J 1992, 11, 291-303
-
(1992)
EMBO J
, vol.11
, pp. 291-303
-
-
Pryciak, P.M.1
Sil, A.2
Varmus, H.E.3
-
40
-
-
0024996730
-
Sequence requirements for integration of Moloney murine leukemia virus DNA in vitro
-
Bushman, F. D.; Craigie, R. Sequence requirements for integration of Moloney murine leukemia virus DNA in vitro. J. Virol. 1990, 64, 5645-5648
-
(1990)
J. Virol.
, vol.64
, pp. 5645-5648
-
-
Bushman, F.D.1
Craigie, R.2
-
41
-
-
0026696624
-
Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection
-
Pryciak, P. M.; Varmus, H. E. Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection. Cell 1992, 69, 769-780
-
(1992)
Cell
, vol.69
, pp. 769-780
-
-
Pryciak, P.M.1
Varmus, H.E.2
-
42
-
-
0026537415
-
Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae
-
Leavitt, A. D.; Rose, R. B.; Varmus, H. E. Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae. J. Virol. 1992, 66, 2359-2368
-
(1992)
J. Virol.
, vol.66
, pp. 2359-2368
-
-
Leavitt, A.D.1
Rose, R.B.2
Varmus, H.E.3
-
43
-
-
0029838374
-
Sequence analysis of the human DNA flanking sites of human immunodeficiency virus type 1 integration
-
Stevens, S.W.; Griffith, J. D. Sequence analysis of the human DNA flanking sites of human immunodeficiency virus type 1 integration. J. Virol. 1996, 70, 6459-6462
-
(1996)
J. Virol.
, vol.70
, pp. 6459-6462
-
-
Stevens, S.W.1
Griffith, J.D.2
-
44
-
-
0030219760
-
Targetsequence preferences of HIV-1 integration complexes in vitro
-
Bor, Y. C.; Miller,M. D.; Bushman, F. D.; Orgel, L. E. Targetsequence preferences of HIV-1 integration complexes in vitro. Virology 1996, 222, 283-288
-
(1996)
Virology
, vol.222
, pp. 283-288
-
-
Bor, Y.C.1
Miller, M.D.2
Bushman, F.D.3
Orgel, L.E.4
-
45
-
-
0031957564
-
Chromosome structure and human immunodeficiency virus type 1 cDNA integration: Centromeric alphoid repeats are a disfavored target
-
Carteau, S.; Hoffmann, C.; Bushman, F. Chromosome structure and human immunodeficiency virus type 1 cDNA integration: Centromeric alphoid repeats are a disfavored target. J. Virol. 1998, 72, 4005-4014
-
(1998)
J. Virol.
, vol.72
, pp. 4005-4014
-
-
Carteau, S.1
Hoffmann, C.2
Bushman, F.3
-
46
-
-
17844381584
-
Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites
-
Holman, A. G.; Coffin, J. M. Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites. Proc. Natl. Acad. Sci. USA 2005, 102, 6103-6107
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 6103-6107
-
-
Holman, A.G.1
Coffin, J.M.2
-
47
-
-
16244386233
-
Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses
-
Wu, X.; Li, Y.; Crise, B.; Burgess, S. M.; Munroe, D. J. Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses. J. Virol. 2005, 79, 5211-5214
-
(2005)
J. Virol.
, vol.79
, pp. 5211-5214
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
Munroe, D.J.5
-
48
-
-
33751418954
-
Selection of target sites for mobile DNA integration in the human genome
-
Berry, C.; Hannenhalli, S.; Leipzig, J.; Bushman, F. D. Selection of target sites for mobile DNA integration in the human genome. PLoS Comput. Biol. 2006. 2, e157
-
(2006)
PLoS Comput. Biol.
, vol.2
-
-
Berry, C.1
Hannenhalli, S.2
Leipzig, J.3
Bushman, F.D.4
-
49
-
-
0028264042
-
Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core
-
Pruss, D.; Bushman, F. D.; Wolffe, A. P. Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core. Proc. Natl. Acad. Sci. USA 1994, 91, 5913-5917
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5913-5917
-
-
Pruss, D.1
Bushman, F.D.2
Wolffe, A.P.3
-
50
-
-
0028125005
-
The influence of DNA and nucleosome structure on integration events directed by HIV integrase
-
Pruss, D.; Reeves, R.; Bushman, F. D.; Wolffe, A. P. The influence of DNA and nucleosome structure on integration events directed by HIV integrase. J. Biol. Chem. 1994, 269, 25031-25041
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25031-25041
-
-
Pruss, D.1
Reeves, R.2
Bushman, F.D.3
Wolffe, A.P.4
-
51
-
-
0028067639
-
EDNAbending creates favored sites for retroviral integration: An explanation for preferred insertion sites in nucleosomes
-
Muller,H. P.;Varmus, H. E.DNAbending creates favored sites for retroviral integration: An explanation for preferred insertion sites in nucleosomes. EMBO J 1994, 13, 4704-4714
-
(1994)
EMBO J
, vol.13
, pp. 4704-4714
-
-
Muller, H.P.1
Varmus, H.2
-
52
-
-
0028364393
-
Substrate features important for recognition and catalysis by human immunodeficiency virus type 1 integrase identified by using novel DNA substrates
-
Chow, S. A.; Brown, P. O. Substrate features important for recognition and catalysis by human immunodeficiency virus type 1 integrase identified by using novel DNA substrates. J. Virol. 1994, 68, 3896-3907
-
(1994)
J. Virol.
, vol.68
, pp. 3896-3907
-
-
Chow, S.A.1
Brown, P.O.2
-
53
-
-
0028874669
-
In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends
-
Bor, Y. C.; Bushman, F. D.; Orgel, L. E. In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends. Proc. Natl. Acad. Sci. USA 1995, 92, 10334-10338
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10334-10338
-
-
Bor, Y.C.1
Bushman, F.D.2
Orgel, L.E.3
-
54
-
-
2442707756
-
Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro
-
Taganov, K. D.; Cuesta, I.; Daniel, R.; Cirillo, L. A.; Katz, R. A.; Zaret, K. S.; Skalka, A. M. Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro. J. Virol. 2004, 78, 5848-5855
-
(2004)
J. Virol.
, vol.78
, pp. 5848-5855
-
-
Taganov, K.D.1
Cuesta, I.2
Daniel, R.3
Cirillo, L.A.4
Katz, R.A.5
Zaret, K.S.6
Skalka, A.M.7
-
55
-
-
0028074881
-
Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences
-
Bushman, F. D. Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences. Proc. Natl. Acad. Sci. USA 1994, 91, 9233-9237
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9233-9237
-
-
Bushman, F.D.1
-
56
-
-
0028940992
-
Targeting retroviral integration
-
Bushman, F. Targeting retroviral integration. Science 1995, 267, 1443-1444
-
(1995)
Science
, vol.267
, pp. 1443-1444
-
-
Bushman, F.1
-
57
-
-
0029360534
-
Target DNA capture by HIV-1 integration complexes
-
Miller, M. D.; Bor, Y. C.; Bushman, F. Target DNA capture by HIV-1 integration complexes. Curr. Biol. 1995, 5, 1047-1056
-
(1995)
Curr. Biol.
, vol.5
, pp. 1047-1056
-
-
Miller, M.D.1
Bor, Y.C.2
Bushman, F.3
-
58
-
-
0029655849
-
Directed integration of viral DNA mediated by fusion proteins consisting of human immunodeficiency virus type 1 integrase and Escherichia coli LexA protein
-
Goulaouic, H.; Chow, S. A. Directed integration of viral DNA mediated by fusion proteins consisting of human immunodeficiency virus type 1 integrase and Escherichia coli LexA protein. J. Virol. 1996, 70, 37-46
-
(1996)
J. Virol.
, vol.70
, pp. 37-46
-
-
Goulaouic, H.1
Chow, S.A.2
-
59
-
-
0029862622
-
Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: In vitro activities and incorporation of a fusion protein into viral particles
-
Katz, R. A.; Merkel, G.; Skalka, A. M. Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: In vitro activities and incorporation of a fusion protein into viral particles. Virology 1996, 217, 178-190
-
(1996)
Virology
, vol.217
, pp. 178-190
-
-
Katz, R.A.1
Merkel, G.2
Skalka, A.M.3
-
60
-
-
0031060377
-
Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites
-
Bushman, F. D.; Miller, M. D. Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites. J. Virol. 1997, 71, 458-464
-
(1997)
J. Virol.
, vol.71
, pp. 458-464
-
-
Bushman, F.D.1
Miller, M.D.2
-
61
-
-
0034466856
-
Integrase-lexA fusion proteins incorporated into human immunodeficiency virus type 1 that contains a catalytically inactive integrase gene are functional to mediate integration
-
Holmes-Son, M. L.; Chow, S. A. Integrase-lexA fusion proteins incorporated into human immunodeficiency virus type 1 that contains a catalytically inactive integrase gene are functional to mediate integration. J. Virol. 2000, 74, 11548-11556
-
(2000)
J. Virol.
, vol.74
, pp. 11548-11556
-
-
Holmes-Son, M.L.1
Chow, S.A.2
-
62
-
-
0035220160
-
Molecular genetics and target site specificity of retroviral integration
-
Holmes-Son, M. L.; Appa, R. S.; Chow, S. A. Molecular genetics and target site specificity of retroviral integration. Adv. Genet. 2001, 43, 33-69
-
(2001)
Adv. Genet.
, vol.43
, pp. 33-69
-
-
Holmes-Son, M.L.1
Appa, R.S.2
Chow, S.A.3
-
63
-
-
0036222329
-
Correct integration mediated by integrase-LexA fusion proteins incorporated into HIV-1
-
Holmes-Son, M. L.; Chow, S. A. Correct integration mediated by integrase-LexA fusion proteins incorporated into HIV-1. Mol. Ther. 2002, 5, 360-370
-
(2002)
Mol. Ther.
, vol.5
, pp. 360-370
-
-
Holmes-Son, M.L.1
Chow, S.A.2
-
64
-
-
0347634423
-
Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites
-
Tan,W.; Zhu, K.; Segal, D. J.; Barbas, C. F., 3rd; Chow, S. A. Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites. J. Virol. 2004, 78, 1301-1313
-
(2004)
J. Virol.
, vol.78
, pp. 1301-1313
-
-
Tan, W.1
Zhu, K.2
Segal, D.J.3
Barbas III, C.F.4
Chow, S.A.5
-
65
-
-
32444434997
-
Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells
-
Tan, W.; Dong, Z.; Wilkinson, T. A.; Barbas, C. F., 3rd; Chow, S. A. Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells. J. Virol. 2006, 80, 1939-1948
-
(2006)
J. Virol.
, vol.80
, pp. 1939-1948
-
-
Tan, W.1
Dong, Z.2
Wilkinson, T.A.3
Barbas III, C.F.4
Chow, S.A.5
-
66
-
-
33750626259
-
Modulating target site selection during human immunodeficiency virus DNA integration in vitro with an engineered tethering factor
-
Ciuffi, A.; Diamond, T. L.; Hwang, Y.; Marshall, H. M.; Bushman, F. D. Modulating target site selection during human immunodeficiency virus DNA integration in vitro with an engineered tethering factor. Hum. Gene. Ther. 2006, 17, 960-967
-
(2006)
Hum. Gene. Ther.
, vol.17
, pp. 960-967
-
-
Ciuffi, A.1
Diamond, T.L.2
Hwang, Y.3
Marshall, H.M.4
Bushman, F.D.5
-
67
-
-
0035895505
-
The sequence of the human genome
-
Venter, J. C.; Adams, M. D.; Myers, E. W.; Li, P. W.; Mural, R. J.; et al. The sequence of the human genome. Science 2001, 291, 1304-1351
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
-
68
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E. S.; Linton, L. M.; Birren, B.; Nusbaum, C.; Zody, M. C.; et al. Initial sequencing and analysis of the human genome. Nature 2001, 409, 860-921
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
-
69
-
-
0035865087
-
A physical map of the human genome
-
McPherson, J. D.; Marra, M.; Hillier, L.; Waterston, R. H.; Chinwalla, A.; et al. A physical map of the human genome. Nature 2001, 409, 934-941
-
(2001)
Nature
, vol.409
, pp. 934-941
-
-
McPherson, J.D.1
Marra, M.2
Hillier, L.3
Waterston, R.H.4
Chinwalla, A.5
-
70
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
Waterston, R. H.; Lindblad-Toh, K.; Birney, E.; Rogers, J.; Abril, J. F.; et al. Initial sequencing and comparative analysis of the mouse genome. Nature 2002, 420, 520-562
-
(2002)
Nature
, vol.420
, pp. 520-562
-
-
Waterston, R.H.1
Lindblad-Toh, K.2
Birney, E.3
Rogers, J.4
Abril, J.F.5
-
71
-
-
10644283823
-
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
-
Consortium, I. C. G. S. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 2004, 432, 695-716
-
(2004)
Nature
, vol.432
, pp. 695-716
-
-
Consortium, I.C.G.S.1
-
72
-
-
24344500211
-
Initial sequence of the chimpanzee genome and comparison with the human genome
-
Consortium, T. C. S. a. A. Initial sequence of the chimpanzee genome and comparison with the human genome. Nature 2005, 437, 69-87
-
(2005)
Nature
, vol.437
, pp. 69-87
-
-
Consortium, T.C.S.A.A.1
-
73
-
-
28644447707
-
Genome sequence, comparative analysis and haplotype structure of the domestic dog
-
Lindblad-Toh, K.; Wade, C. M.; Mikkelsen, T. S.; Karlsson, E. K.; Jaffe, D. B.; et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 2005, 438, 803-819
-
(2005)
Nature
, vol.438
, pp. 803-819
-
-
Lindblad-Toh, K.1
Wade, C.M.2
Mikkelsen, T.S.3
Karlsson, E.K.4
Jaffe, D.B.5
-
74
-
-
0037162715
-
HIV-1 integration in the human genome favors active genes and local hotspots
-
Schroder, A. R.; Shinn, P.; Chen, H.; Berry, C.; Ecker, J. R.; Bushman, F. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 2002, 110, 521-529
-
(2002)
Cell
, vol.110
, pp. 521-529
-
-
Schroder, A.R.1
Shinn, P.2
Chen, H.3
Berry, C.4
Ecker, J.R.5
Bushman, F.6
-
75
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
Wu, X.; Li, Y.; Crise, B.; Burgess, S. M. Transcription start regions in the human genome are favored targets for MLV integration. Science 2003, 300, 1749-1751
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
76
-
-
19344375031
-
Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences
-
Mitchell, R. S.; Beitzel, B. F.; Schroder, A. R.; Shinn, P.; Chen, H.; Berry, C. C.; Ecker, J. R.; Bushman, F. D. Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences. PLoS Biol 2004, 2, E234
-
(2004)
PLoS Biol
, vol.2
-
-
Mitchell, R.S.1
Beitzel, B.F.2
Schroder, A.R.3
Shinn, P.4
Chen, H.5
Berry, C.C.6
Ecker, J.R.7
Bushman, F.D.8
-
77
-
-
20044396722
-
Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells
-
Hematti, P.; Hong, B. K.; Ferguson, C.; Adler, R.; Hanawa, H.; Sellers, S.; Holt, I. E.; Eckfeldt, C. E.; Sharma, Y.; Schmidt, M.; von Kalle, C.; Persons, D. A.; Billings, E. M.; Verfaillie, C. M.; Nienhuis, A. W.; Wolfsberg, T. G.; Dunbar, C. E.; Calmels, B. Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells. PLoS Biol 2004, 2, e423
-
(2004)
PLoS Biol
, vol.2
-
-
Hematti, P.1
Hong, B.K.2
Ferguson, C.3
Adler, R.4
Hanawa, H.5
Sellers, S.6
Holt, I.E.7
Eckfeldt, C.E.8
Sharma, Y.9
Schmidt, M.10
von Kalle, C.11
Persons, D.A.12
Billings, E.M.13
Verfaillie, C.M.14
Nienhuis, A.W.15
Wolfsberg, T.G.16
Dunbar, C.E.17
Calmels, B.18
-
78
-
-
6344270072
-
Genomewide analyses of avian sarcoma virus integration sites
-
Narezkina, A.; Taganov, K. D.; Litwin, S.; Stoyanova, R.; Hayashi, J.; Seeger, C.; Skalka, A. M.; Katz, R. A. Genomewide analyses of avian sarcoma virus integration sites. J. Virol. 2004, 78, 11656-11663
-
(2004)
J. Virol.
, vol.78
, pp. 11656-11663
-
-
Narezkina, A.1
Taganov, K.D.2
Litwin, S.3
Stoyanova, R.4
Hayashi, J.5
Seeger, C.6
Skalka, A.M.7
Katz, R.A.8
-
79
-
-
28644443483
-
A role for LEDGF/p75 in targeting HIV DNA integration
-
Ciuffi, A.; Llano, M.; Poeschla, E.; Hoffmann, C.; Leipzig, J.; Shinn, P.; Ecker, J. R.; Bushman, F. A role for LEDGF/p75 in targeting HIV DNA integration. Nat. Med. 2005. 11, 1287-1289
-
(2005)
Nat. Med.
, vol.11
, pp. 1287-1289
-
-
Ciuffi, A.1
Llano, M.2
Poeschla, E.3
Hoffmann, C.4
Leipzig, J.5
Shinn, P.6
Ecker, J.R.7
Bushman, F.8
-
80
-
-
24644489049
-
Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome
-
Barr, S. D.; Leipzig, J.; Shinn, P.; Ecker, J. R.; Bushman, F. D. Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome. J. Virol. 2005. 79, 12035-12044
-
(2005)
J. Virol.
, vol.79
, pp. 12035-12044
-
-
Barr, S.D.1
Leipzig, J.2
Shinn, P.3
Ecker, J.R.4
Bushman, F.D.5
-
81
-
-
25144445833
-
Simian immunodeficiency virus integration preference is similar to that of human immunodeficiency virus type 1
-
Crise, B.; Li, Y.; Yuan, C.; Morcock, D. R.; Whitby, D.; Munroe, D. J.; Arthur, L. O.; Wu, X. Simian immunodeficiency virus integration preference is similar to that of human immunodeficiency virus type 1. J. Virol. 2005, 79, 12199-12204
-
(2005)
J. Virol.
, vol.79
, pp. 12199-12204
-
-
Crise, B.1
Li, Y.2
Yuan, C.3
Morcock, D.R.4
Whitby, D.5
Munroe, D.J.6
Arthur, L.O.7
Wu, X.8
-
82
-
-
23044476591
-
Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states
-
Doi, K.; Wu, X.; Taniguchi, Y.; Yasunaga, J.; Satou, Y.; Okayama, A.; Nosaka, K.; Matsuoka, M. Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states. Blood 2005, 106, 1048-1053
-
(2005)
Blood
, vol.106
, pp. 1048-1053
-
-
Doi, K.1
Wu, X.2
Taniguchi, Y.3
Yasunaga, J.4
Satou, Y.5
Okayama, A.6
Nosaka, K.7
Matsuoka, M.8
-
83
-
-
33646161948
-
Genome-wide mapping of foamy virus vector integrations into a human cell line
-
Nowrouzi, A.; Dittrich, M.; Klanke, C.; Heinkelein, M.; Rammling, M.; Dandekar, T.; von Kalle, C.; Rethwilm, A. Genome-wide mapping of foamy virus vector integrations into a human cell line. J. Gen. Virol. 2006, 87, 1339-1347
-
(2006)
J. Gen. Virol.
, vol.87
, pp. 1339-1347
-
-
Nowrouzi, A.1
Dittrich, M.2
Klanke, C.3
Heinkelein, M.4
Rammling, M.5
Dandekar, T.6
von Kalle, C.7
Rethwilm, A.8
-
84
-
-
33745684269
-
Retroviral DNA integration: Viral and cellular determinants of target-site selection
-
Lewinski, M. K.; Yamashita, M.; Emerman, M.; Ciuffi, A.; Marshall, H.; Crawford, G.; Collins, F.; Shinn, P.; Leipzig, J.; Hannenhalli, S.; Berry, C. C.; Ecker, J. R.; Bushman, F. D. Retroviral DNA integration: Viral and cellular determinants of target-site selection. PLoS Pathog. 2006. 2, e60
-
(2006)
PLoS Pathog
, vol.2
-
-
Lewinski, M.K.1
Yamashita, M.2
Emerman, M.3
Ciuffi, A.4
Marshall, H.5
Crawford, G.6
Collins, F.7
Shinn, P.8
Leipzig, J.9
Hannenhalli, S.10
Berry, C.C.11
Ecker, J.R.12
Bushman, F.D.13
-
85
-
-
33745363486
-
HIV integration site selection: Targeting in macrophages and the effects of different routes of viral entry
-
Barr, S. D.; Ciuffi, A.; Leipzig, J.; Shinn, P.; Ecker, J. R.; Bushman, F. D. HIV integration site selection: Targeting in macrophages and the effects of different routes of viral entry. Mol. Ther. 2006. 14, 218-225
-
(2006)
Mol. Ther.
, vol.14
, pp. 218-225
-
-
Barr, S.D.1
Ciuffi, A.2
Leipzig, J.3
Shinn, P.4
Ecker, J.R.5
Bushman, F.D.6
-
86
-
-
30344434648
-
Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts
-
Ciuffi, A.; Mitchell, R. S.; Hoffmann, C.; Leipzig, J.; Shinn, P.; Ecker, J. R.; Bushman, F. D. Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts. Mol. Ther. 2006. 13, 366-373
-
(2006)
Mol. Ther.
, vol.13
, pp. 366-373
-
-
Ciuffi, A.1
Mitchell, R.S.2
Hoffmann, C.3
Leipzig, J.4
Shinn, P.5
Ecker, J.R.6
Bushman, F.D.7
-
87
-
-
31944444349
-
Foamy virus vector integration sites in normal human cells
-
Trobridge, G. D.; Miller, D. G.; Jacobs, M. A.; Allen, J. M.; Kiem, H. P.; Kaul, R.; Russell, D. W. Foamy virus vector integration sites in normal human cells. Proc. Natl. Acad. Sci. USA 2006, 103, 1498-1503
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 1498-1503
-
-
Trobridge, G.D.1
Miller, D.G.2
Jacobs, M.A.3
Allen, J.M.4
Kiem, H.P.5
Kaul, R.6
Russell, D.W.7
-
88
-
-
33748205021
-
The integration profile of EIAV-based vectors
-
Hacker, C. V.; Vink, C. A.; Wardell, T. W.; Lee, S.; Treasure, P.; Kingsman, S. M.; Mitrophanous, K. A.; Miskin, J. E. The integration profile of EIAV-based vectors. Mol. Ther. 2006, 14, 536-545
-
(2006)
Mol. Ther.
, vol.14
, pp. 536-545
-
-
Hacker, C.V.1
Vink, C.A.2
Wardell, T.W.3
Lee, S.4
Treasure, P.5
Kingsman, S.M.6
Mitrophanous, K.A.7
Miskin, J.E.8
-
89
-
-
33750699347
-
A high-throughput method for cloning and sequencing human immunodeficiency virus type 1 integration sites
-
Kim, S.; Kim, Y.; Liang, T.; Sinsheimer, J. S.; Chow, S. A. A high-throughput method for cloning and sequencing human immunodeficiency virus type 1 integration sites. J. Virol. 2006, 80, 11313-11321
-
(2006)
J. Virol.
, vol.80
, pp. 11313-11321
-
-
Kim, S.1
Kim, Y.2
Liang, T.3
Sinsheimer, J.S.4
Chow, S.A.5
-
90
-
-
33751251058
-
Gene transfer in humans using a conditionally replicating lentiviral vector
-
Levine, B. L.; Humeau, L. M.; Boyer, J.; MacGregor, R. R.; Rebello, T.; Lu, X.; Binder, G. K.; Slepushkin, V.; Lemiale, F.; Mascola, J. R.; Bushman, F. D.; Dropulic, B.; June, C. H. Gene transfer in humans using a conditionally replicating lentiviral vector. Proc. Natl. Acad. Sci. USA 2006, 103, 17372-17377
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 17372-17377
-
-
Levine, B.L.1
Humeau, L.M.2
Boyer, J.3
MacGregor, R.R.4
Rebello, T.5
Lu, X.6
Binder, G.K.7
Slepushkin, V.8
Lemiale, F.9
Mascola, J.R.10
Bushman, F.D.11
Dropulic, B.12
June, C.H.13
-
91
-
-
33746210165
-
Genomic sites of human immunodeficiency virus type 2 (HIV-2) integration: similarities to HIV-1 in vitro and possible differences in vivo
-
MacNeil, A.; Sankale, J. L.; Meloni, S. T.; Sarr, A. D.; Mboup, S.; Kanki, P. Genomic sites of human immunodeficiency virus type 2 (HIV-2) integration: similarities to HIV-1 in vitro and possible differences in vivo. J. Virol. 2006, 80, 7316-7321
-
(2006)
J. Virol.
, vol.80
, pp. 7316-7321
-
-
MacNeil, A.1
Sankale, J.L.2
Meloni, S.T.3
Sarr, A.D.4
Mboup, S.5
Kanki, P.6
-
92
-
-
33745414660
-
Integration bias of gammaretrovirus vectors following transduction and growth of primary mouse hematopoietic progenitor cells with and without selection
-
Aker, M.; Tubb, J.; Miller, D. G.; Stamatoyannopoulos, G.; Emery, D. W. Integration bias of gammaretrovirus vectors following transduction and growth of primary mouse hematopoietic progenitor cells with and without selection. Mol. Ther. 2006, 14, 226-235
-
(2006)
Mol. Ther.
, vol.14
, pp. 226-235
-
-
Aker, M.1
Tubb, J.2
Miller, D.G.3
Stamatoyannopoulos, G.4
Emery, D.W.5
-
93
-
-
33750728451
-
Porcine endogenous retrovirus integration sites in the human genome: Features in common with those of murine leukemia virus
-
Moalic, Y.; Blanchard, Y.; Felix, H.; Jestin, A. Porcine endogenous retrovirus integration sites in the human genome: Features in common with those of murine leukemia virus. J. Virol. 2006, 80, 10980-10988
-
(2006)
J. Virol.
, vol.80
, pp. 10980-10988
-
-
Moalic, Y.1
Blanchard, Y.2
Felix, H.3
Jestin, A.4
-
94
-
-
33847016906
-
Recurrent HIV-1 integration at the BACH2 locus in resting CD4{thorn} T cell populations during effective highly active antiretroviral therapy
-
Ikeda, T.; Shibata, J.; Yoshimura, K.; Koito, A.; Matsushita, S. Recurrent HIV-1 integration at the BACH2 locus in resting CD4{thorn} T cell populations during effective highly active antiretroviral therapy. J. Infect. Dis. 2007, 195, 716-725
-
(2007)
J. Infect. Dis.
, vol.195
, pp. 716-725
-
-
Ikeda, T.1
Shibata, J.2
Yoshimura, K.3
Koito, A.4
Matsushita, S.5
-
95
-
-
34547635063
-
HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications
-
Wang, G. P.; Ciuffi, A.; Leipzig, J.; Berry, C. C.; Bushman, F. D. HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications. Genome Res. 2007. 17, 1186-1194
-
(2007)
Genome Res
, vol.17
, pp. 1186-1194
-
-
Wang, G.P.1
Ciuffi, A.2
Leipzig, J.3
Berry, C.C.4
Bushman, F.D.5
-
96
-
-
34249952425
-
Human T-cell leukemia virus type 1 integration target sites in the human genome: Comparison with those of other retroviruses
-
Derse, D.; Crise, B.; Li, Y.; Princler, G.; Lum, N.; Stewart, C.; McGrath, C. F.; Hughes, S. H.; Munroe, D. J.;Wu, X. Human T-cell leukemia virus type 1 integration target sites in the human genome: Comparison with those of other retroviruses. J. Virol. 2007, 81, 6731-6741
-
(2007)
J. Virol.
, vol.81
, pp. 6731-6741
-
-
Derse, D.1
Crise, B.2
Li, Y.3
Princler, G.4
Lum, N.5
Stewart, C.6
McGrath, C.F.7
Hughes, S.H.8
Munroe, D.J.9
Wu, X.10
-
97
-
-
34249804819
-
Unique integration profiles in a canine model of long-term repopulating cells transduced with gammaretrovirus, lentivirus, or foamy virus
-
Beard, B. C.; Keyser, K. A.; Trobridge, G. D.; Peterson, L. J.; Miller, D. G.; Jacobs, M.; Kaul, R.; Kiem, H. P. Unique integration profiles in a canine model of long-term repopulating cells transduced with gammaretrovirus, lentivirus, or foamy virus. Hum. Gene. Ther. 2007, 18, 423-434
-
(2007)
Hum. Gene. Ther.
, vol.18
, pp. 423-434
-
-
Beard, B.C.1
Keyser, K.A.2
Trobridge, G.D.3
Peterson, L.J.4
Miller, D.G.5
Jacobs, M.6
Kaul, R.7
Kiem, H.P.8
-
98
-
-
34250851635
-
Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells
-
Beard, B. C.; Dickerson, D.; Beebe, K.; Gooch, C.; Fletcher, J.; Okbinoglu, T.; Miller, D. G.; Jacobs, M. A.; Kaul, R.; Kiem, H. P.; Trobridge, G. D. Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells. Mol. Ther. 2007, 15, 1356-1365
-
(2007)
Mol. Ther.
, vol.15
, pp. 1356-1365
-
-
Beard, B.C.1
Dickerson, D.2
Beebe, K.3
Gooch, C.4
Fletcher, J.5
Okbinoglu, T.6
Miller, D.G.7
Jacobs, M.A.8
Kaul, R.9
Kiem, H.P.10
Trobridge, G.D.11
-
99
-
-
34447513231
-
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
-
Shun, M. C.; Raghavendra, N. K.; Vandegraaff, N.; Daigle, J. E.; Hughes, S.; Kellam, P.; Cherepanov, P.; Engelman, A. LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. Genes Dev. 2007, 21, 1767-1778
-
(2007)
Genes Dev
, vol.21
, pp. 1767-1778
-
-
Shun, M.C.1
Raghavendra, N.K.2
Vandegraaff, N.3
Daigle, J.E.4
Hughes, S.5
Kellam, P.6
Cherepanov, P.7
Engelman, A.8
-
100
-
-
33748639703
-
Integration site choice of a feline immunodeficiency virus vector
-
Kang, Y.; Moressi, C. J.; Scheetz, T. E.; Xie, L.; Tran, D. T.; Casavant, T. L.; Ak, P.; Benham, C. J.; Davidson, B. L.; McCray, P. B., Jr., Integration site choice of a feline immunodeficiency virus vector. J. Virol. 2006, 80, 8820-8823
-
(2006)
J. Virol.
, vol.80
, pp. 8820-8823
-
-
Kang, Y.1
Moressi, C.J.2
Scheetz, T.E.3
Xie, L.4
Tran, D.T.5
Casavant, T.L.6
Ak, P.7
Benham, C.J.8
Davidson, B.L.9
McCray Jr, P.B.10
-
101
-
-
44349171666
-
Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting
-
Marshall, H. M.; Ronen, K.; Berry, C.; Llano, M.; Sutherland, H.; Saenz, D.; Bickmore, W.; Poeschla, E.; Bushman, F. D. Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting. PLoS ONE 2007, 2, e1340
-
(2007)
PLoS ONE
, vol.2
-
-
Marshall, H.M.1
Ronen, K.2
Berry, C.3
Llano, M.4
Sutherland, H.5
Saenz, D.6
Bickmore, W.7
Poeschla, E.8
Bushman, F.D.9
-
102
-
-
38349112349
-
Mouse mammary tumor virus integration site selection in human and mouse genomes
-
Faschinger, A.; Rouault, F.; Sollner, J.; Lukas, A.; Salmons, B.; Gunzburg, W. H.; Indik, S. Mouse mammary tumor virus integration site selection in human and mouse genomes. J. Virol. 2008, 83, 1360-1367
-
(2008)
J. Virol.
, vol.83
, pp. 1360-1367
-
-
Faschinger, A.1
Rouault, F.2
Sollner, J.3
Lukas, A.4
Salmons, B.5
Gunzburg, W.H.6
Indik, S.7
-
103
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
Margulies, M.; Egholm, M.; Altman,W. E.; Attiya, S.; Bader, J. S.; Bemben, L. A.; Berka, J.; Braverman, M. S.; Chen, Y. J.; Chen, Z.; Dewell, S. B.; Du, L.; Fierro, J. M.; Gomes, X. V.; Godwin, B. C.; He, W.; Helgesen, S.; Ho, C. H.; Irzyk, G. P.; Jando, S. C.; Alenquer,M. L.; Jarvie, T. P.; Jirage, K. B.; Kim, J. B.; Knight, J. R.; Lanza, J. R.; Leamon, J. H.; Lefkowitz, S. M.; Lei, M.; Li, J.; Lohman, K. L.; Lu, H.; Makhijani, V. B.; McDade, K. E.; McKenna, M. P.; Myers, E.W.; Nickerson, E.; Nobile, J. R.; Plant, R.; Puc, B. P.; Ronan, M. T.; Roth, G. T.; Sarkis, G. J.; Simons, J. F.; Simpson, J. W.; Srinivasan, M.; Tartaro, K. R.; Tomasz, A.;Vogt, K. A.;Volkmer,G. A.;Wang, S. H.;Wang, Y.;Weiner,M. P.; Yu, P.; Begley, R. F.; Rothberg, J. M. Genome sequencing in microfabricated high-density picolitre reactors. Nature 2005, 437, 376-380
-
(2005)
Nature
, vol.437
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
Attiya, S.4
Bader, J.S.5
Bemben, L.A.6
Berka, J.7
Braverman, M.S.8
Chen, Y.J.9
Chen, Z.10
Dewell, S.B.11
Du, L.12
Fierro, J.M.13
Gomes, X.V.14
Godwin, B.C.15
He, W.16
Helgesen, S.17
Ho, C.H.18
Irzyk, G.P.19
Jando, S.C.20
Alenquer, M.L.21
Jarvie, T.P.22
Jirage, K.B.23
Kim, J.B.24
Knight, J.R.25
Lanza, J.R.26
Leamon, J.H.27
Lefkowitz, S.M.28
Lei, M.29
Li, J.30
Lohman, K.L.31
Lu, H.32
Makhijani, V.B.33
McDade, K.E.34
McKenna, M.P.35
Myers, E.W.36
Nickerson, E.37
Nobile, J.R.38
Plant, R.39
Puc, B.P.40
Ronan, M.T.41
Roth, G.T.42
Sarkis, G.J.43
Simons, J.F.44
Simpson, J.W.45
Srinivasan, M.46
Tartaro, K.R.47
Tomasz, A.48
Vogt, K.A.49
Volkmer, G.A.50
Wang, S.H.51
Wang, Y.52
Weiner, M.P.53
Yu, P.54
Begley, R.F.55
Rothberg, J.M.56
more..
-
104
-
-
7444260846
-
The ENCODE (ENCyclopedia Of DNA Elements) Project
-
Consortium, T. E. P. The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 2004, 306, 636-640
-
(2004)
Science
, vol.306
, pp. 636-640
-
-
Consortium, T.E.P.1
-
105
-
-
34250305146
-
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
-
Consortium, T. E. P. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007, 447, 799-816
-
(2007)
Nature
, vol.447
, pp. 799-816
-
-
Consortium, T.E.P.1
-
106
-
-
33747500567
-
A genomic code for nucleosome positioning
-
Segal, E.; Fondufe-Mittendorf, Y.; Chen, L.; Thastrom, A.; Field, Y.; Moore, I. K.;Wang, J. P.;Widom, J. A genomic code for nucleosome positioning. Nature 2006, 442, 772-778
-
(2006)
Nature
, vol.442
, pp. 772-778
-
-
Segal, E.1
Fondufe-Mittendorf, Y.2
Chen, L.3
Thastrom, A.4
Field, Y.5
Moore, I.K.6
Wang, J.P.7
Widom, J.8
-
107
-
-
0023038804
-
Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin
-
Vijaya, S.; Steffen, D. L.; Robinson, H. L. Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin. J. Virol. 1986, 60, 683-692
-
(1986)
J. Virol.
, vol.60
, pp. 683-692
-
-
Vijaya, S.1
Steffen, D.L.2
Robinson, H.L.3
-
108
-
-
0023152463
-
Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites
-
Rohdewohld, H.;Weiher, H.; Reik,W.; Jaenisch, R.; Breindl, M. Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites. J. Virol. 1987, 61, 336-343
-
(1987)
J. Virol.
, vol.61
, pp. 336-343
-
-
Rohdewohld, H.1
Weiher, H.2
Reik, W.3
Jaenisch, R.4
Breindl, M.5
-
109
-
-
30044449116
-
Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)
-
Crawford, G. E.; Holt, I. E.; Whittle, J.;Webb, B. D.; Tai, D.; Davis, S.; Margulies, E. H.; Chen, Y.; Bernat, J. A.; Ginsburg, D.; Zhou, D.; Luo, S.; Vasicek, T. J.; Daly, M. J.; Wolfsberg, T. G.; Collins, F. S. Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). Genome Res. 2006, 16, 123-131
-
(2006)
Genome Res
, vol.16
, pp. 123-131
-
-
Crawford, G.E.1
Holt, I.E.2
Whittle, J.3
Webb, B.D.4
Tai, D.5
Davis, S.6
Margulies, E.H.7
Chen, Y.8
Bernat, J.A.9
Ginsburg, D.10
Zhou, D.11
Luo, S.12
Vasicek, T.J.13
Daly, M.J.14
Wolfsberg, T.G.15
Collins, F.S.16
-
110
-
-
0027158091
-
Integration of murine leukemia virus DNA depends on mitosis
-
Roe, T.; Reynolds, T. C.; Yu, G.; Brown, P. O. Integration of murine leukemia virus DNA depends on mitosis. EMBO J 1993, 12, 2099-2108
-
(1993)
EMBO J
, vol.12
, pp. 2099-2108
-
-
Roe, T.1
Reynolds, T.C.2
Yu, G.3
Brown, P.O.4
-
111
-
-
0041856142
-
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells
-
Maertens, G.; Cherepanov, P.; Pluymers, W.; Busschots, K.; De Clercq, E.; Debyser, Z.; Engelborghs, Y. LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells. J. Biol. Chem. 2003, 278, 33528-33539
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33528-33539
-
-
Maertens, G.1
Cherepanov, P.2
Pluymers, W.3
Busschots, K.4
De Clercq, E.5
Debyser, Z.6
Engelborghs, Y.7
-
112
-
-
10344221084
-
Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
-
Cherepanov, P.; Devroe, E.; Silver, P. A.; Engelman, A. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. J. Biol. Chem. 2004, 279, 48883-48892
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48883-48892
-
-
Cherepanov, P.1
Devroe, E.2
Silver, P.A.3
Engelman, A.4
-
113
-
-
4043112782
-
Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75
-
Maertens, G.; Cherepanov, P.; Debyser, Z.; Engelborghs, Y.; Engelman, A. Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75. J. Biol. Chem. 2004, 279, 33421-33429
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33421-33429
-
-
Maertens, G.1
Cherepanov, P.2
Debyser, Z.3
Engelborghs, Y.4
Engelman, A.5
-
114
-
-
11244255412
-
Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase
-
Llano, M.; Delgado, S.; Vanegas, M.; Poeschla, E. M. Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase. J. Biol. Chem. 2004, 279, 55570-55577
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 55570-55577
-
-
Llano, M.1
Delgado, S.2
Vanegas, M.3
Poeschla, E.M.4
-
115
-
-
4143092604
-
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
-
Llano, M.; Vanegas, M.; Fregoso, O.; Saenz, D.; Chung, S.; Peretz, M.; Poeschla, E. M. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J. Virol. 2004, 78, 9524-9537
-
(2004)
J. Virol.
, vol.78
, pp. 9524-9537
-
-
Llano, M.1
Vanegas, M.2
Fregoso, O.3
Saenz, D.4
Chung, S.5
Peretz, M.6
Poeschla, E.M.7
-
116
-
-
28444445583
-
Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
-
Cherepanov, P.; Ambrosio, A. L.; Rahman, S.; Ellenberger, T.; Engelman, A. Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75. Proc. Natl. Acad. Sci. USA 2005, 102, 17308-17313
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 17308-17313
-
-
Cherepanov, P.1
Ambrosio, A.L.2
Rahman, S.3
Ellenberger, T.4
Engelman, A.5
-
117
-
-
22444437424
-
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
-
Cherepanov, P.; Sun, Z. Y.; Rahman, S.; Maertens, G.; Wagner, G.; Engelman, A. Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75. Nat. Struct. Mol. Biol. 2005, 12, 526-532
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 526-532
-
-
Cherepanov, P.1
Sun, Z.Y.2
Rahman, S.3
Maertens, G.4
Wagner, G.5
Engelman, A.6
-
118
-
-
18844429520
-
Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLSindependent chromatin tethering
-
Vanegas,M.; Llano, M.; Delgado, S.; Thompson, D.; Peretz, M.; Poeschla, E. Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLSindependent chromatin tethering. J. Cell. Sci. 2005, 118, 1733-1743
-
(2005)
J. Cell. Sci.
, vol.118
, pp. 1733-1743
-
-
Vanegas, M.1
Llano, M.2
Delgado, S.3
Thompson, D.4
Peretz, M.5
Poeschla, E.6
-
119
-
-
24044489892
-
The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding
-
Busschots, K.; Vercammen, J.; Emiliani, S.; Benarous, R.; Engelborghs, Y.; Christ, F.; Debyser, Z. The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding. J. Biol. Chem. 2005, 280, 17841-17847
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17841-17847
-
-
Busschots, K.1
Vercammen, J.2
Emiliani, S.3
Benarous, R.4
Engelborghs, Y.5
Christ, F.6
Debyser, Z.7
-
120
-
-
21844431868
-
Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication
-
Emiliani, S.; Mousnier, A.; Busschots, K.; Maroun, M.; Van Maele, B.; Tempe, D.; Vandekerckhove, L.; Moisant, F.; Ben-Slama, L.; Witvrouw, M.; Christ, F.; Rain, J. C.; Dargemont, C.; Debyser, Z.; Benarous, R. Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication. J. Biol. Chem. 2005, 280, 25517-25523
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25517-25523
-
-
Emiliani, S.1
Mousnier, A.2
Busschots, K.3
Maroun, M.4
Van Maele, B.5
Tempe, D.6
Vandekerckhove, L.7
Moisant, F.8
Ben-Slama, L.9
Witvrouw, M.10
Christ, F.11
Rain, J.C.12
Dargemont, C.13
Debyser, Z.14
Benarous, R.15
-
121
-
-
33645528413
-
A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo
-
Turlure, F.; Maertens, G.; Rahman, S.; Cherepanov, P.; Engelman, A. A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo. Nucleic Acids Res. 2006, 34, 1653-1675
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1653-1675
-
-
Turlure, F.1
Maertens, G.2
Rahman, S.3
Cherepanov, P.4
Engelman, A.5
-
122
-
-
32444439020
-
Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus
-
Vandekerckhove, L.; Christ, F.; Van Maele, B.; De Rijck, J.; Gijsbers, R.; Van den Haute, C.; Witvrouw, M.; Debyser, Z. Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus. J. Virol. 2006, 80, 1886-1896
-
(2006)
J. Virol.
, vol.80
, pp. 1886-1896
-
-
Vandekerckhove, L.1
Christ, F.2
Van Maele, B.3
De Rijck, J.4
Gijsbers, R.5
Van den Haute, C.6
Witvrouw, M.7
Debyser, Z.8
-
123
-
-
33750358735
-
An essential role for LEDGF/p75 in HIV integration
-
Llano, M.; Saenz, D. T.; Meehan, A.; Wongthida, P.; Peretz, M.;Walker,W. H.; Teo,W.; Poeschla, E. M. An essential role for LEDGF/p75 in HIV integration. Science 2006, 314, 461-464
-
(2006)
Science
, vol.314
, pp. 461-464
-
-
Llano, M.1
Saenz, D.T.2
Meehan, A.3
Wongthida, P.4
Peretz, M.5
Walker, W.H.6
Teo, W.7
Poeschla, E.M.8
-
124
-
-
33745617039
-
Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75
-
Llano, M.;Vanegas, M.;Hutchins, N.;Thompson, D.; Delgado, S.; Poeschla, E. M. Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75. J. Mol. Biol. 2006, 360, 760-773
-
(2006)
J. Mol. Biol.
, vol.360
, pp. 760-773
-
-
Llano, M.1
Vanegas, M.2
Hutchins, N.3
Thompson, D.4
Delgado, S.5
Poeschla, E.M.6
-
125
-
-
33751242046
-
Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication
-
De Rijck, J.; Vandekerckhove, L.; Gijsbers, R.; Hombrouck, A.; Hendrix, J.; Vercammen, J.; Engelborghs, Y.; Christ, F.; Debyser, Z. Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication. J. Virol. 2006, 80, 11498-11509
-
(2006)
J. Virol.
, vol.80
, pp. 11498-11509
-
-
De Rijck, J.1
Vandekerckhove, L.2
Gijsbers, R.3
Hombrouck, A.4
Hendrix, J.5
Vercammen, J.6
Engelborghs, Y.7
Christ, F.8
Debyser, Z.9
-
126
-
-
33846049539
-
Identification of the LEDGF/p75 binding site in HIV-1 integrase
-
Busschots, K.; Voet, A.; De Maeyer, M.; Rain, J. C.; Emiliani, S.; Benarous, R.; Desender, L.; Debyser, Z.; Christ, F. Identification of the LEDGF/p75 binding site in HIV-1 integrase. J. Mol. Biol. 2007, 365, 1480-1492
-
(2007)
J. Mol. Biol.
, vol.365
, pp. 1480-1492
-
-
Busschots, K.1
Voet, A.2
De Maeyer, M.3
Rain, J.C.4
Emiliani, S.5
Benarous, R.6
Desender, L.7
Debyser, Z.8
Christ, F.9
-
127
-
-
33846652601
-
LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro
-
Cherepanov, P. LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro. Nucleic Acids Res. 2007, 35, 113-124
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 113-124
-
-
Cherepanov, P.1
-
128
-
-
0242492858
-
The human polycomb group EED protein interacts with the integrase of human immunodeficiency virus type 1
-
Violot, S.; Hong, S. S.; Rakotobe, D.; Petit, C.; Gay, B.; Moreau, K.; Billaud, G.; Priet, S.; Sire, J.; Schwartz, O.; Mouscadet, J. F.; Boulanger, P. The human polycomb group EED protein interacts with the integrase of human immunodeficiency virus type 1. J. Virol. 2003, 77, 12507-12522
-
(2003)
J. Virol.
, vol.77
, pp. 12507-12522
-
-
Violot, S.1
Hong, S.S.2
Rakotobe, D.3
Petit, C.4
Gay, B.5
Moreau, K.6
Billaud, G.7
Priet, S.8
Sire, J.9
Schwartz, O.10
Mouscadet, J.F.11
Boulanger, P.12
-
129
-
-
0028566214
-
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5
-
Kalpana, G. V.; Marmon, S.; Wang, W.; Crabtree, G. R.; Goff, S. P. Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science 1994, 266, 2002-2006
-
(1994)
Science
, vol.266
, pp. 2002-2006
-
-
Kalpana, G.V.1
Marmon, S.2
Wang, W.3
Crabtree, G.R.4
Goff, S.P.5
-
130
-
-
27144463461
-
Acetylationof HIV-1 integrase by p300 regulates viral integration
-
Cereseto, A.; Manganaro, L.; Gutierrez, M. I.; Terreni, M.; Fittipaldi, A.; Lusic, M.; Marcello, A.; Giacca, M. Acetylationof HIV-1 integrase by p300 regulates viral integration.EMBOJ 2005, 24, 3070-3081
-
(2005)
EMBOJ
, vol.24
, pp. 3070-3081
-
-
Cereseto, A.1
Manganaro, L.2
Gutierrez, M.I.3
Terreni, M.4
Fittipaldi, A.5
Lusic, M.6
Marcello, A.7
Giacca, M.8
-
131
-
-
33847657288
-
Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication
-
Topper, M.; Luo, Y.; Zhadina, M.; Mohammed, K.; Smith, L.; Muesing, M. A. Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication. J. Virol. 2007, 81, 3012-3017
-
(2007)
J. Virol.
, vol.81
, pp. 3012-3017
-
-
Topper, M.1
Luo, Y.2
Zhadina, M.3
Mohammed, K.4
Smith, L.5
Muesing, M.A.6
-
132
-
-
20444433204
-
Measuring protein-protein interactions inside living cells using single color fluorescence correlation spectroscopy Application to human immunodeficiency virus type 1 integrase and LEDGF/p75
-
Maertens, G.; Vercammen, J.; Debyser, Z.; Engelborghs, Y. Measuring protein-protein interactions inside living cells using single color fluorescence correlation spectroscopy. Application to human immunodeficiency virus type 1 integrase and LEDGF/p75. FASEB J. 2005, 19, 1039-1041
-
(2005)
FASEB J
, vol.19
, pp. 1039-1041
-
-
Maertens, G.1
Vercammen, J.2
Debyser, Z.3
Engelborghs, Y.4
-
133
-
-
33746070075
-
Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin
-
Maertens, G.N.; Cherepanov,P.; Engelman,A. Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin. J. Cell. Sci. 2006, 119, 2563-2571
-
(2006)
J. Cell. Sci.
, vol.119
, pp. 2563-2571
-
-
Maertens, G.N.1
Cherepanov, P.2
Engelman, A.3
-
134
-
-
34047200871
-
Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV
-
Hombrouck, A.; De Rijck, J.; Hendrix, J.; Vandekerckhove, L.; Voet, A.; De Maeyer, M.;Witvrouw, M.; Engelborghs, Y.; Christ, F.; Gijsbers, R.; Debyser, Z. Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV. PLoS Pathog. 2007, 3, e47
-
(2007)
PLoS Pathog
, vol.3
-
-
Hombrouck, A.1
De Rijck, J.2
Hendrix, J.3
Vandekerckhove, L.4
Voet, A.5
De Maeyer, M.6
Witvrouw, M.7
Engelborghs, Y.8
Christ, F.9
Gijsbers, R.10
Debyser, Z.11
-
135
-
-
34347226332
-
Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium
-
Hayouka, Z.; Rosenbluh, J.; Levin, A.; Loya, S.; Lebendiker, M.; Veprintsev, D.; Kotler, M.; Hizi, A.; Loyter, A.; Friedler, A. Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium. Proc. Natl. Acad. Sci. USA 2007, 104, 8316-8321
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 8316-8321
-
-
Hayouka, Z.1
Rosenbluh, J.2
Levin, A.3
Loya, S.4
Lebendiker, M.5
Veprintsev, D.6
Kotler, M.7
Hizi, A.8
Loyter, A.9
Friedler, A.10
-
136
-
-
34247128760
-
Transcriptional coactivator LEDGF/p75 modulates human immunodeficiency virus type 1 integrase-mediated concerted integration
-
Pandey, K. K.; Sinha, S.; Grandgenett, D. P. Transcriptional coactivator LEDGF/p75 modulates human immunodeficiency virus type 1 integrase-mediated concerted integration. J. Virol. 2007, 81, 3969-3979
-
(2007)
J. Virol.
, vol.81
, pp. 3969-3979
-
-
Pandey, K.K.1
Sinha, S.2
Grandgenett, D.P.3
-
137
-
-
33847279490
-
LEDGF/p75 interferes with the formation of synaptic nucleoprotein complexes that catalyze full-site HIV-1 DNA integration in vitro: Implications for the mechanism of viral cDNA integration
-
Raghavendra, N. K.; Engelman, A. LEDGF/p75 interferes with the formation of synaptic nucleoprotein complexes that catalyze full-site HIV-1 DNA integration in vitro: Implications for the mechanism of viral cDNA integration. Virology 2007, 360, 1-5
-
(2007)
Virology
, vol.360
, pp. 1-5
-
-
Raghavendra, N.K.1
Engelman, A.2
-
138
-
-
33751417052
-
Structure-based mutagenesis of the integrase-LEDGF/ p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness
-
Rahman, S.; Lu, R.; Vandegraaff, N.; Cherepanov, P.; Engelman, A. Structure-based mutagenesis of the integrase-LEDGF/ p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness. Virology 2007, 357, 79-90
-
(2007)
Virology
, vol.357
, pp. 79-90
-
-
Rahman, S.1
Lu, R.2
Vandegraaff, N.3
Cherepanov, P.4
Engelman, A.5
-
139
-
-
33947240704
-
HIV-1 integrase preassembled on donor DNA is refractory to activity stimulation by LEDGF/p75
-
Yu, F.; Jones, G. S.; Hung, M.; Wagner, A. H.; MacArthur, H. L.; Liu, X.; Leavitt, S.; McDermott, M. J.; Tsiang, M. HIV-1 integrase preassembled on donor DNA is refractory to activity stimulation by LEDGF/p75. Biochemistry 2007, 46, 2899-2908
-
(2007)
Biochemistry
, vol.46
, pp. 2899-2908
-
-
Yu, F.1
Jones, G.S.2
Hung, M.3
Wagner, A.H.4
MacArthur, H.L.5
Liu, X.6
Leavitt, S.7
McDermott, M.J.8
Tsiang, M.9
-
140
-
-
33745776919
-
Modest but reproducible inhibition of human immunodeficiency virus type 1 infection in macrophages following LEDGFp75 silencing
-
Zielske, S. P.; Stevenson, M. Modest but reproducible inhibition of human immunodeficiency virus type 1 infection in macrophages following LEDGFp75 silencing. J. Virol. 2006, 80, 7275-7280
-
(2006)
J. Virol.
, vol.80
, pp. 7275-7280
-
-
Zielske, S.P.1
Stevenson, M.2
-
141
-
-
0035068122
-
Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain
-
Molteni, V.; Greenwald, J.; Rhodes, D.; Hwang, Y.; Kwiatkowski, W.; Bushman, F. D.; Siegel, J. S.; Choe, S. Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain. Acta Crystallogr. D. Biol. Crystallogr. 2001, 57, 536-544
-
(2001)
Acta Crystallogr. D. Biol. Crystallogr.
, vol.57
, pp. 536-544
-
-
Molteni, V.1
Greenwald, J.2
Rhodes, D.3
Hwang, Y.4
Kwiatkowski, W.5
Bushman, F.D.6
Siegel, J.S.7
Choe, S.8
-
142
-
-
33745623119
-
Discovery of a small-molecule HIV-1 integrase inhibitor-binding site
-
Al-Mawsawi, L. Q.; Fikkert, V.; Dayam, R.; Witvrouw, M.; Burke, T. R., Jr.; Borchers, C. H.; Neamati, N. Discovery of a small-molecule HIV-1 integrase inhibitor-binding site. Proc. Natl. Acad. Sci. USA 2006, 103, 10080-10085
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10080-10085
-
-
Al-Mawsawi, L.Q.1
Fikkert, V.2
Dayam, R.3
Witvrouw, M.4
Burke Jr, T.R.5
Borchers, C.H.6
Neamati, N.7
-
143
-
-
42149180682
-
Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase-DNA complex formation and catalysis
-
Al-Mawsawi, L. Q.; Christ, F.; Dayam, R.; Debyser, Z.; Neamati, N. Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase-DNA complex formation and catalysis. FEBS Lett. 2008, 582, 1425-1430
-
(2008)
FEBS Lett
, vol.582
, pp. 1425-1430
-
-
Al-Mawsawi, L.Q.1
Christ, F.2
Dayam, R.3
Debyser, Z.4
Neamati, N.5
-
144
-
-
34547691354
-
Retroviral integration and human gene therapy
-
Bushman, F. D. Retroviral integration and human gene therapy. J. Clin. Invest. 2007, 117, 2083-2086
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2083-2086
-
-
Bushman, F.D.1
-
145
-
-
35549013276
-
New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy
-
Pike-Overzet, K.; van der Burg, M.; Wagemaker, G.; van Dongen, J. J.; Staal, F. J. New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy. Mol. Ther. 2007, 15, 1910-1916
-
(2007)
Mol. Ther.
, vol.15
, pp. 1910-1916
-
-
Pike-Overzet, K.1
van der Burg, M.2
Wagemaker, G.3
van Dongen, J.J.4
Staal, F.J.5
-
146
-
-
34249890562
-
Gene therapy for severe combined immunodeficiency: Are we there yet? J
-
Cavazzana-Calvo, M.; Fischer, A. Gene therapy for severe combined immunodeficiency: Are we there yet? J. Clin. Invest. 2007, 117, 1456-1465
-
(2007)
Clin. Invest.
, vol.117
, pp. 1456-1465
-
-
Cavazzana-Calvo, M.1
Fischer, A.2
-
147
-
-
39449124736
-
The ethics of human gene transfer
-
Kimmelman, J. The ethics of human gene transfer. Nat. Rev. Genet. 2008, 9, 239-244
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 239-244
-
-
Kimmelman, J.1
-
148
-
-
0034724857
-
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
-
Cavazzana-Calvo, M.; Hacein-Bey, S.; de Saint Basile, G.; Gross, F.; Yvon, E.; Nusbaum, P.; Selz, F.; Hue, C.; Certain, S.; Casanova, J. L.; Bousso, P.; Deist, F. L.; Fischer, A. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 2000, 288, 669-672
-
(2000)
Science
, vol.288
, pp. 669-672
-
-
Cavazzana-Calvo, M.1
Hacein-Bey, S.2
de Saint Basile, G.3
Gross, F.4
Yvon, E.5
Nusbaum, P.6
Selz, F.7
Hue, C.8
Certain, S.9
Casanova, J.L.10
Bousso, P.11
Deist, F.L.12
Fischer, A.13
-
149
-
-
14544269487
-
Gene therapy for severe combined immunodeficiency
-
Cavazzana-Calvo, M.; Lagresle, C.; Hacein-Bey-Abina, S.; Fischer, A. Gene therapy for severe combined immunodeficiency. Annu. Rev. Med. 2005, 56, 585-602
-
(2005)
Annu. Rev. Med.
, vol.56
, pp. 585-602
-
-
Cavazzana-Calvo, M.1
Lagresle, C.2
Hacein-Bey-Abina, S.3
Fischer, A.4
-
150
-
-
19944421384
-
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
-
Gaspar, H. B.; Parsley, K. L.; Howe, S.; King, D.; Gilmour, K. C.; Sinclair, J.; Brouns, G.; Schmidt, M.; Von Kalle, C.; Barington, T.; Jakobsen, M. A.; Christensen, H. O.; Al Ghonaium, A.; White, H. N.; Smith, J. L.; Levinsky, R. J.; Ali, R. R.; Kinnon, C.; Thrasher, A. J. Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector. Lancet 2004. 364, 2181-2187
-
(2004)
Lancet
, vol.364
, pp. 2181-2187
-
-
Gaspar, H.B.1
Parsley, K.L.2
Howe, S.3
King, D.4
Gilmour, K.C.5
Sinclair, J.6
Brouns, G.7
Schmidt, M.8
Von Kalle, C.9
Barington, T.10
Jakobsen, M.A.11
Christensen, H.O.12
Al Ghonaium, A.13
White, H.N.14
Smith, J.L.15
Levinsky, R.J.16
Ali, R.R.17
Kinnon, C.18
Thrasher, A.J.19
-
151
-
-
34547651095
-
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo
-
Schwarzwaelder, K.; Howe, S. J.; Schmidt, M.; Brugman, M. H.; Deichmann, A.; Glimm, H.; Schmidt, S.; Prinz, C.; Wissler, M.; King, D. J.; Zhang, F.; Parsley, K. L.; Gilmour, K. C.; Sinclair, J.; Bayford, J.; Peraj, R.; Pike-Overzet, K.; Staal, F. J.; de Ridder, D.; Kinnon, C.; Abel, U.; Wagemaker, G.; Gaspar, H. B.; Thrasher, A. J.; von Kalle, C. Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo. J. Clin. Invest. 2007, 117, 2241-2249
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2241-2249
-
-
Schwarzwaelder, K.1
Howe, S.J.2
Schmidt, M.3
Brugman, M.H.4
Deichmann, A.5
Glimm, H.6
Schmidt, S.7
Prinz, C.8
Wissler, M.9
King, D.J.10
Zhang, F.11
Parsley, K.L.12
Gilmour, K.C.13
Sinclair, J.14
Bayford, J.15
Peraj, R.16
Pike-Overzet, K.17
Staal, F.J.18
de Ridder, D.19
Kinnon, C.20
Abel, U.21
Wagemaker, G.22
Gaspar, H.B.23
Thrasher, A.J.24
von Kalle, C.25
more..
-
152
-
-
0037189401
-
Correction of ADASCID by stem cell gene therapy combined with nonmyeloablative conditioning
-
Aiuti, A.; Slavin, S.; Aker, M.; Ficara, F.; Deola, S.; Mortellaro, A.; Morecki, S.; Andolfi, G.; Tabucchi, A.; Carlucci, F.; Marinello, E.; Cattaneo, F.; Vai, S.; Servida, P.; Miniero, R.; Roncarolo, M. G.; Bordignon, C. Correction of ADASCID by stem cell gene therapy combined with nonmyeloablative conditioning. Science 2002, 296, 2410-2413
-
(2002)
Science
, vol.296
, pp. 2410-2413
-
-
Aiuti, A.1
Slavin, S.2
Aker, M.3
Ficara, F.4
Deola, S.5
Mortellaro, A.6
Morecki, S.7
Andolfi, G.8
Tabucchi, A.9
Carlucci, F.10
Marinello, E.11
Cattaneo, F.12
Vai, S.13
Servida, P.14
Miniero, R.15
Roncarolo, M.G.16
Bordignon, C.17
-
153
-
-
33645734405
-
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1
-
Ott, M. G.; Schmidt, M.; Schwarzwaelder, K.; Stein, S.; Siler, U.; Koehl, U.; Glimm, H.; Kuhlcke, K.; Schilz, A.; Kunkel, H.; Naundorf, S.; Brinkmann, A.; Deichmann, A.; Fischer, M.; Ball, C.; Pilz, I.; Dunbar, C.; Du, Y.; Jenkins, N. A.; Copeland, N. G.; Luthi, U.; Hassan, M.; Thrasher, A. J.; Hoelzer, D.; von Kalle, C.; Seger, R.; Grez, M. Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat. Med. 2006, 12, 401-409
-
(2006)
PRDM16 or SETBP1. Nat. Med.
, vol.12
, pp. 401-409
-
-
Ott, M.G.1
Schmidt, M.2
Schwarzwaelder, K.3
Stein, S.4
Siler, U.5
Koehl, U.6
Glimm, H.7
Kuhlcke, K.8
Schilz, A.9
Kunkel, H.10
Naundorf, S.11
Brinkmann, A.12
Deichmann, A.13
Fischer, M.14
Ball, C.15
Pilz, I.16
Dunbar, C.17
Du, Y.18
Jenkins, N.A.19
Copeland, N.G.20
Luthi, U.21
Hassan, M.22
Thrasher, A.J.23
Hoelzer, D.24
von Kalle, C.25
Seger, R.26
Grez, M.27
more..
-
154
-
-
33748413936
-
Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning
-
Gaspar, H. B.; Bjorkegren, E.; Parsley, K.; Gilmour, K. C.; King, D.; Sinclair, J.; Zhang, F.; Giannakopoulos, A.; Adams, S.; Fairbanks, L. D.; Gaspar, J.; Henderson, L.; Xu-Bayford, J. H.; Davies, E. G.; Veys, P. A.; Kinnon, C.; Thrasher, A. J. Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning. Mol. Ther. 2006, 14, 505-513
-
(2006)
Mol. Ther.
, vol.14
, pp. 505-513
-
-
Gaspar, H.B.1
Bjorkegren, E.2
Parsley, K.3
Gilmour, K.C.4
King, D.5
Sinclair, J.6
Zhang, F.7
Giannakopoulos, A.8
Adams, S.9
Fairbanks, L.D.10
Gaspar, J.11
Henderson, L.12
Xu-Bayford, J.H.13
Davies, E.G.14
Veys, P.A.15
Kinnon, C.16
Thrasher, A.J.17
-
155
-
-
0038687288
-
Gene therapy of X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina, S.; de Saint Basile, G.; Cavazzana-Calvo, M. Gene therapy of X-linked severe combined immunodeficiency. Methods Mol. Biol. 2003, 215, 247-259
-
(2003)
Methods Mol. Biol.
, vol.215
, pp. 247-259
-
-
Hacein-Bey-Abina, S.1
de Saint Basile, G.2
Cavazzana-Calvo, M.3
-
156
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina, S.; von Kalle, C.; Schmidt, M.; Le Deist, F.; Wulffraat, N.; McIntyre, E.; Radford, I.; Villeval, J. L.; Fraser, C. C.; Cavazzana-Calvo, M.; Fischer, A. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 2003, 348, 255-256
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
von Kalle, C.2
Schmidt, M.3
Le Deist, F.4
Wulffraat, N.5
McIntyre, E.6
Radford, I.7
Villeval, J.L.8
Fraser, C.C.9
Cavazzana-Calvo, M.10
Fischer, A.11
-
157
-
-
34249906359
-
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
-
Deichmann, A.; Hacein-Bey-Abina, S.; Schmidt, M.; Garrigue, A.; Brugman, M. H.; Hu, J.; Glimm, H.; Gyapay, G.; Prum, B.; Fraser, C. C.; Fischer, N.; Schwarzwaelder, K.; Siegler, M. L.; de Ridder, D.; Pike-Overzet, K.; Howe, S. J.; Thrasher, A. J.; Wagemaker, G.; Abel, U.; Staal, F. J.; Delabesse, E.; Villeval, J. L.; Aronow, B.; Hue, C.; Prinz, C.; Wissler, M.; Klanke, C.; Weissenbach, J.; Alexander, I.; Fischer, A.; von Kalle, C.; Cavazzana-Calvo, M. Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy. J. Clin. Invest. 2007, 117, 2225-2232
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2225-2232
-
-
Deichmann, A.1
Hacein-Bey-Abina, S.2
Schmidt, M.3
Garrigue, A.4
Brugman, M.H.5
Hu, J.6
Glimm, H.7
Gyapay, G.8
Prum, B.9
Fraser, C.C.10
Fischer, N.11
Schwarzwaelder, K.12
Siegler, M.L.13
de Ridder, D.14
Pike-Overzet, K.15
Howe, S.J.16
Thrasher, A.J.17
Wagemaker, G.18
Abel, U.19
Staal, F.J.20
Delabesse, E.21
Villeval, J.L.22
Aronow, B.23
Hue, C.24
Prinz, C.25
Wissler, M.26
Klanke, C.27
Weissenbach, J.28
Alexander, I.29
Fischer, A.30
von Kalle, C.31
Cavazzana-Calvo, M.32
more..
-
158
-
-
0346132122
-
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells
-
Yu, S. F.; von Ruden, T.; Kantoff, P. W.; Garber, C.; Seiberg, M.; Ruther, U.; Anderson, W. F.; Wagner, E. F.; Gilboa, E. Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proc. Natl. Acad. Sci. USA 1986, 83, 3194-3198
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 3194-3198
-
-
Yu, S.F.1
von Ruden, T.2
Kantoff, P.W.3
Garber, C.4
Seiberg, M.5
Ruther, U.6
Anderson, W.F.7
Wagner, E.F.8
Gilboa, E.9
-
159
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L.; Blomer, U.; Gallay, P.; Ory, D.; Mulligan, R.; Gage, F. H.; Verma, I. M.; Trono, D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996, 272, 263-267
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
160
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull, T.; Zufferey, R.; Kelly, M.; Mandel, R. J.; Nguyen, M.; Trono, D.; Naldini, L. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 1998, 72, 8463-8471
-
(1998)
J. Virol.
, vol.72
, pp. 8463-8471
-
-
Dull, T.1
Zufferey, R.2
Kelly, M.3
Mandel, R.J.4
Nguyen, M.5
Trono, D.6
Naldini, L.7
-
161
-
-
0031666744
-
Development of a self-inactivating lentivirus vector
-
Miyoshi, H.; Blomer, U.; Takahashi, M.; Gage, F. H.; Verma, I. M. Development of a self-inactivating lentivirus vector. J. Virol. 1998, 72, 8150-8157
-
(1998)
J. Virol.
, vol.72
, pp. 8150-8157
-
-
Miyoshi, H.1
Blomer, U.2
Takahashi, M.3
Gage, F.H.4
Verma, I.M.5
-
162
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey, R.; Donello, J. E.; Trono, D.; Hope, T. J. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 1999, 73, 2886-2892
-
(1999)
J. Virol.
, vol.73
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
-
163
-
-
0036632178
-
RNA 30 readthrough of oncoretrovirus and lentivirus: Implications for vector safety and efficacy
-
Zaiss, A. K.; Son, S.; Chang, L. J. RNA 30 readthrough of oncoretrovirus and lentivirus: Implications for vector safety and efficacy. J. Virol. 2002, 76, 7209-7219
-
(2002)
J. Virol.
, vol.76
, pp. 7209-7219
-
-
Zaiss, A.K.1
Son, S.2
Chang, L.J.3
-
164
-
-
13844254514
-
Retroviral gene therapy: Safety issues and possible solutions
-
Yi, Y.; Hahm, S. H.; Lee, K. H. Retroviral gene therapy: Safety issues and possible solutions. Curr. Gene. Ther. 2005, 5, 25-35
-
(2005)
Curr. Gene. Ther.
, vol.5
, pp. 25-35
-
-
Yi, Y.1
Hahm, S.H.2
Lee, K.H.3
-
165
-
-
33646875083
-
Retrovirus vectors: Toward the plentivirus? Mol
-
Baum, C.; Schambach, A.; Bohne, J.; Galla, M. Retrovirus vectors: Toward the plentivirus? Mol. Ther. 2006, 13, 1050-1063
-
(2006)
Ther
, vol.13
, pp. 1050-1063
-
-
Baum, C.1
Schambach, A.2
Bohne, J.3
Galla, M.4
-
166
-
-
34848851094
-
Promoter choice for retroviral vectors: Transcriptional strength versus trans-activation potential
-
Weber, E. L.; Cannon, P. M. Promoter choice for retroviral vectors: Transcriptional strength versus trans-activation potential. Hum. Gene. Ther. 2007, 18, 849-860
-
(2007)
Hum. Gene. Ther.
, vol.18
, pp. 849-860
-
-
Weber, E.L.1
Cannon, P.M.2
-
167
-
-
34249298695
-
Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors
-
Schambach, A.; Galla, M.; Maetzig, T.; Loew, R.; Baum, C. Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors. Mol. Ther. 2007, 15, 1167-1173
-
(2007)
Mol. Ther.
, vol.15
, pp. 1167-1173
-
-
Schambach, A.1
Galla, M.2
Maetzig, T.3
Loew, R.4
Baum, C.5
-
168
-
-
34548125356
-
The woodchuck hepatitis virus post-transcriptional regulatory element reduces readthrough transcription from retroviral vectors
-
Higashimoto, T.; Urbinati, F.; Perumbeti, A.; Jiang, G.; Zarzuela, A.; Chang, L. J.; Kohn, D. B.; Malik, P. The woodchuck hepatitis virus post-transcriptional regulatory element reduces readthrough transcription from retroviral vectors. Gene Ther. 2007, 14, 1298-1304
-
(2007)
Gene Ther
, vol.14
, pp. 1298-1304
-
-
Higashimoto, T.1
Urbinati, F.2
Perumbeti, A.3
Jiang, G.4
Zarzuela, A.5
Chang, L.J.6
Kohn, D.B.7
Malik, P.8
-
169
-
-
34548791721
-
Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element
-
Arumugam, P. I.; Scholes, J.; Perelman, N.; Xia, P.; Yee, J. K.; Malik, P. Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element. Mol. Ther. 2007, 15, 1863-1871
-
(2007)
Mol. Ther.
, vol.15
, pp. 1863-1871
-
-
Arumugam, P.I.1
Scholes, J.2
Perelman, N.3
Xia, P.4
Yee, J.K.5
Malik, P.6
-
170
-
-
41149133413
-
Physiological promoters reduce the genotoxic risk of integrating gene vectors
-
Zychlinski, D.; Schambach, A.; Modlich, U.; Maetzig, T.; Meyer, J.; Grassman, E.; Mishra, A.; Baum, C. Physiological promoters reduce the genotoxic risk of integrating gene vectors. Mol. Ther. 2008, 16, 718-725
-
(2008)
Mol. Ther.
, vol.16
, pp. 718-725
-
-
Zychlinski, D.1
Schambach, A.2
Modlich, U.3
Maetzig, T.4
Meyer, J.5
Grassman, E.6
Mishra, A.7
Baum, C.8
-
171
-
-
39849099656
-
Arapid and quantitative assay for measuring neighboring gene activation by vector proviruses
-
Hendrie,P. C.;Huo,Y.; Stolitenko, R. B.; Russell,D.W. Arapid and quantitative assay for measuring neighboring gene activation by vector proviruses. Mol. Ther. 2008, 16, 534-540.
-
(2008)
Mol. Ther.
, vol.16
, pp. 534-540
-
-
Hendrie, P.C.1
Huo, Y.2
Stolitenko, R.B.3
Russell, D.W.4
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