Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 48, 2005, Pages 17308-17313

  Cherepanov, Peter ^a,b   Ambrosio, Andre L B ^b,c   Rahman, Shaila ^a   Ellenberger, Tom ^b   Engelman, Alan ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Host factor; Integration; Retrovirus; Structure; Transcription

Indexed keywords

INTEGRASE; LENS EPITHELIUM DERIVED GROWTH FACTOR; MONOMER; PROTEIN P75;

ARTICLE; CRYSTAL STRUCTURE; ENZYME STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; RETROVIRUS; TRANSCRIPTION REGULATION; VIRUS REPLICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CRYSTALLIZATION; HIV INTEGRASE; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; TRANSCRIPTION FACTORS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 28444445583     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0506924102     Document Type: Article

References (56)

1. Craigie, R. (2002) in Mobile DNA II, eds. Craig, N. L., Craigie, R., Gellert, M. & Lambowitz, A. M. (Am. Soc. Microbiol., Washington, DC), pp. 613-630.
2. Turlure, F., Devroe, E., Silver, P. A. & Engelman, A. (2004) Front. Biosci. 9, 3187-3208.
3. Engelman, A. (2005) Proc. Natl. Acad. Sci. USA 102, 1275-1276.
4. Bushman, F. D. (2003) Cell 115, 135-138.
5. Engelman, A. & Craigie, R. (1992) J. Virol. 66, 6361-6369.
6. Bushman, F. D., Engelman, A., Palmer, I., Wingfield, P. & Craigie, R. (1993) Proc. Natl. Acad. Sci. USA 90, 3428-3432.
7. Cai, M., Zheng, R., Caffrey, M., Craigie, R., Clore, G. M. & Gronenborn, A. M. (1997) Nat. Struct. Biol. 4, 567-577.
8. Dyda, F., Hickman, A. B., Jenkins, T. M., Engelman, A., Craigie, R. & Davies, D. R. (1994) Science 266, 1981-1986.
9. Rice, P. A. & Baker, T. A. (2001) Nat. Struct. Biol. 8, 302-307.
10. Lodi, P. J., Ernst, J. A., Kuszewski, J., Hickman, A. B., Engelman, A., Craigie, R., Clore, G. M. & Gronenborn, A. M. (1995) Biochemistry 34, 9826-9833.
11. Eijkelenboom, A. P., Lutzke, R. A., Boelens, R., Plasterk, R. H., Kaptein, R. & Hard, K. (1995) Nat. Struct. Biol. 2, 807-810.
12. Vink, C., Oude Groeneger, A. M. & Plasterk, R. H. (1993) Nucleic Acids Res. 21, 1419-1425.
13. Engelman, A., Bushman, F. D. & Craigie, R. (1993) EMBO J. 12, 3269-3275.
14. Hickman, A. B., Palmer, I., Engelman, A., Craigie, R. & Wingfield, P. (1994) J. Biol. Chem. 269, 29279-29287.
15. Zheng, R., Jenkins, T. M. & Craigie, R. (1996) Proc. Natl. Acad. Sci. USA 93, 13659-13664.
16. Jenkins, T. M., Engelman, A., Ghirlando, R. & Craigie, R. (1996) J. Biol. Chem. 271, 7712-7718.
17. Lee, S. P., Xiao, J., Knutson, J. R., Lewis, M. S. & Han, M. K. (1997) Biochemistry 36, 173-180.
18. Cherepanov, P., Maertens, G., Proost, P., Devreese, B., Van Beeumen, J., Engelborghs, Y., De Clercq, E. & Debyser, Z. (2003) J. Biol. Chem. 278, 372-381.
19. Petit, C., Schwartz, O. & Mammano, F. (1999) J. Virol. 73, 5079-5088.
20. Pluymers, W., Cherepanov, P., Schols, D., De Clercq, E. & Debyser, Z. (1999) Virology 258, 327-332.
21. Cherepanov, P., Pluymers, W., Claeys, A., Proost, P., De Clercq, E. & Debyser, Z. (2000) FASEB J. 14, 1389-1399.
22. Maertens, G., Cherepanov, P., Pluymers, W., Busschots, K., De Clercq, E., Debyser, Z. & Engelborghs, Y. (2003) J. Biol. Chem. 278, 33528-33539.
23. Maertens, G., Cherepanov, P., Debyser, Z., Engelborghs, Y. & Engelman, A. (2004) J. Biol. Chem. 279, 33421-33429.
24. Llano, M., Vanegas, M., Fregoso, O., Saenz, D., Chung, S., Peretz, M. & Poeschla, E. M. (2004) J. Virol. 78, 9524-9537.
25. Emiliani, S., Mousnier, A., Busschots, K., Maroun, M., Van Maele, B., Tempe, D., Vandekerckhove, L., Moisant, F., Ben-Slama, L., Witvrouw, M., et al. (2005) J. Biol. Chem. 280, 25517-25523.
26. Llano, M., Delgado, S., Vanegas, M. & Poeschla, E. M. (2004) J. Biol. Chem. 279, 55570-55577.
27. Busschots, K., Vercammen, J., Emiliani, S., Benarous, R., Engelborghs, Y., Christ, F. & Debyser, Z. (2005) J. Biol. Chem. 280, 17841-17847.
28. Cherepanov, P., Devroe, E., Silver, P. A. & Engelman, A. (2004) J. Biol. Chem. 279, 48883-48892.
29. Vanegas, M., Llano, M., Delgado, S., Thompson, D., Peretz, M. & Poeschla, E. (2005) J. Cell Sci. 118, 1733-1743.
30. Cherepanov, P., Sun, Z. Y., Rahman, S., Maertens, G., Wagner, G. & Engelman, A. (2005) Nat. Struct. Mol. Biol. 12, 526-532.
31. Andrade, M. A., Petosa, C., O'Donoghue, S. I., Muller, C. W. & Bork, P. (2001) J. Mol. Biol. 309, 1-18.
32. Green, J. B., Gardner, C. D., Wharton, R. P. & Aggarwal, A. K. (2003) Mol. Cell 11, 1537-1548.
33. Otwinowski, Z. & Minor, W. (1997) Methods Enzymol. 276, 307-326.
34. CCP4 (1994) Acta Cryslallogr. D 50, 760-763.
35. Goldgur, Y., Dyda, F., Hickman, A. B., Jenkins, T. M., Craigie, R. & Davies, D. R. (1998) Proc. Natl. Acad. Sci. USA 95, 9150-9154.
36. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., et al. (1998) Acta Crystallogr. D 54, 905-921.
37. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997) Acta Crystallogr. D 53, 240-255.
38. Winn, M. D., Murshudov, G. N. & Papiz, M. Z. (2003) Methods Enzymol. 374, 300-321.
39. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119.
40. Emsley, P. & Cowtan, K. (2004) Acta Crystallogr. D 60, 2126-2132.
41. Koradi, R., Billeter, M. & Wuthrich, K. (1996) J. Mol. Graphics 14, 51-55, 29-32.
42. Jenkins, T. M., Hickman, A. B., Dyda, F., Ghirlando, R., Davies, D. R. & Craigie, R. (1995) Proc. Natl. Acad. Sci. USA 92, 6057-6061.
43. Wang, J. Y., Ling, H., Yang, W. & Craigie, R. (2001) EMBO J. 20, 7333-7343.
44. Lo Conte, L., Chothia, C. & Janin, J. (1999) J. Mol. Biol. 285, 2177-2198.
45. Maignan, S., Guilloteau, J. P., Zhou-Liu, Q., Clement-Mella, C. & Mikol, V. (1998) J. Mol. Biol. 282, 359-368.
46. Chen, Z., Yan, Y., Munshi, S., Li, Y., Zugay-Murphy, J., Xu, B., Witmer, M., Felock, P., Wolfe, A., Sardana, V., et al. (2000) J. Mol. Biol. 296, 521-533.
47. Lubkowski, J., Dauter, Z., Yang, F., Alexandratos, J., Merkel, G., Skalka, A. M. & Wlodawer, A. (1999) Biochemistry 38, 13512-13522.
48. Yang, Z. N., Mueser, T. C., Bushman, F. D. & Hyde, C. C. (2000) J. Mol. Biol. 296, 535-548.
49. Bouyac-Bertoia, M., Dvorin, J. D., Fouchier, R. A., Jenkins, Y., Meyer, B. E., Wu, L. I., Emerman, M. & Malim, M. H. (2001) Mol. Cell 7, 1025-1035.
50. Lu, R., Limon, A., Devroe, E., Silver, P. A., Cherepanov, P. & Engelman, A. (2004) J. Virol. 78, 12735-12746.
51. Molteni, V., Greenwald, J., Rhodes, D., Hwang, Y., Kwiatkowski, W., Bushman, F. D., Siegel, J. S. & Choe, S. (2001) Acta Crystallogr. D 57, 536-544.
52. Lin, Z., Neamati, N., Zhao, H., Kiryu, Y., Turpin, J. A., Aberham, C., Strebel, K., Kohn, K., Witvrouw, M., Pannecouque, C., et al. (1999) J. Med. Chem. 42, 1401-1414.
53. Shkriabai, N., Patil, S. S., Hess, S., Budihas, S. R., Craigie, R., Burke, T. R., Jr., Le Grice, S. F. & Kvaratskhelia, M. (2004) Proc. Natl. Acad. Sci. USA 101, 6894-6899.
54. Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., et al. (2004) Science 303, 844-848.
55. Lepourcelet, M., Chen, Y. N., France, D. S., Wang, H., Crews, P., Petersen, F., Bruseo, C., Wood, A. W. & Shivdasani, R. A. (2004) Cancer Cell 5, 91-102.
56. Gouet, P., Courcelle, E., Stuart, D. I. & Metoz, F. (1999) Bioinformatics 15, 305-308.