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Volumn 15, Issue 6, 2007, Pages 1167-1173

Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; MESSENGER RNA; RETROVIRUS VECTOR;

EID: 34249298695     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300152     Document Type: Article
Times cited : (113)

References (40)
  • 1
    • 0030784958 scopus 로고    scopus 로고
    • Mechanism and regulation of mRNA polyadenylation
    • Colgan, DF and Manley, JL (1997). Mechanism and regulation of mRNA polyadenylation. Genes Dev 11: 2755-2766.
    • (1997) Genes Dev , vol.11 , pp. 2755-2766
    • Colgan, D.F.1    Manley, J.L.2
  • 2
    • 0033059981 scopus 로고    scopus 로고
    • Formation of mRNA 3′ ends in eukaryotes: Mechanism, regulation, and interrelationships with other steps in mRNA synthesis
    • Zhao, J, Hyman, L and Moore, C (1999). Formation of mRNA 3′ ends in eukaryotes: Mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol Mol Biol Rev 63: 405-445.
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 405-445
    • Zhao, J.1    Hyman, L.2    Moore, C.3
  • 3
    • 0037164730 scopus 로고    scopus 로고
    • Polyadenylation: A tail of two complexes
    • Proudfoot, N and O'Sullivan, J (2002). Polyadenylation: A tail of two complexes. Curr Biol 12: R855-R857.
    • (2002) Curr Biol , vol.12
    • Proudfoot, N.1    O'Sullivan, J.2
  • 5
    • 0035171959 scopus 로고    scopus 로고
    • The retroviruses human immunodeficiency virus type 1 and Moloney murine leukemia virus adopt radically different strategies to regulate promoter-proximal polyadenylation
    • Furger, A, Monks, J and Proudfoot, NJ (2001). The retroviruses human immunodeficiency virus type 1 and Moloney murine leukemia virus adopt radically different strategies to regulate promoter-proximal polyadenylation. J Virol 75: 11735-11746.
    • (2001) J Virol , vol.75 , pp. 11735-11746
    • Furger, A.1    Monks, J.2    Proudfoot, N.J.3
  • 6
    • 0346132122 scopus 로고
    • Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells
    • Yu, SF, von Ruden, T, Kantoff, Pw, Garber, C, Seiberg, M, Ruther, U et al. (1986). Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proc Natl Acad Sci USA 83: 3194-3198.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 3194-3198
    • Yu, S.F.1    von Ruden, T.2    Kantoff, P.3    Garber, C.4    Seiberg, M.5    Ruther, U.6
  • 7
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • Dull, T, Zufferey, R, Kelly, M, Mandel, RJ, Nguyen, M, Trono, D et al. (1998). A third-generation lentivirus vector with a conditional packaging system. J Virol 72: 8463-4471.
    • (1998) J Virol , vol.72 , pp. 8463-4471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3    Mandel, R.J.4    Nguyen, M.5    Trono, D.6
  • 8
    • 30344464717 scopus 로고    scopus 로고
    • Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells
    • Schambach, A, Bohne, J, Chandra, S, Will, E, Margison, GP, Williams, DA et al. (2006). Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells. Mol Ther 13: 391-400.
    • (2006) Mol Ther , vol.13 , pp. 391-400
    • Schambach, A.1    Bohne, J.2    Chandra, S.3    Will, E.4    Margison, G.P.5    Williams, D.A.6
  • 9
    • 0036632178 scopus 로고    scopus 로고
    • RNA 3′ readthrough of oncoretrovirus and lentrvirus: Implications for vector safety and efficacy
    • Zalss, AK, Son, S and Chang, LJ (2002). RNA 3′ readthrough of oncoretrovirus and lentrvirus: Implications for vector safety and efficacy. J Virol 76: 7209-7219.
    • (2002) J Virol , vol.76 , pp. 7209-7219
    • Zalss, A.K.1    Son, S.2    Chang, L.J.3
  • 10
    • 0026463514 scopus 로고
    • Activation of HIV-1 pre-mRNA 3′ processing in vitro requires both an upstream element and TAR
    • Gilmartin, GM, Fleming, ES and Oetjen, J (1992). Activation of HIV-1 pre-mRNA 3′ processing in vitro requires both an upstream element and TAR. EMBO J 11: 4419-4428.
    • (1992) EMBO J , vol.11 , pp. 4419-4428
    • Gilmartin, G.M.1    Fleming, E.S.2    Oetjen, J.3
  • 11
    • 27944496521 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis: Past, present and future
    • Uren, AG, Kool, J, Berns, A and van Lohuizen, M (2005). Retroviral insertional mutagenesis: Past, present and future. Oncogene 24 7656-7672.
    • (2005) Oncogene , vol.24 , pp. 7656-7672
    • Uren, A.G.1    Kool, J.2    Berns, A.3    van Lohuizen, M.4
  • 12
    • 33847408501 scopus 로고    scopus 로고
    • Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways
    • Kustikova, O, Geiger, H, Li, Z, Brugman, MH, Chambers, SM, Shaw, CA et al. (2006). Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood 109: 1897-1907.
    • (2006) Blood , vol.109 , pp. 1897-1907
    • Kustikova, O.1    Geiger, H.2    Li, Z.3    Brugman, M.H.4    Chambers, S.M.5    Shaw, C.A.6
  • 15
    • 0037841763 scopus 로고    scopus 로고
    • Transcription start regions in the human genome are favored targets for MLV integration
    • Wu, X, Li, Y, Crise, B and Burgess, SM (2003). Transcription start regions in the human genome are favored targets for MLV integration. Science 300: 1749-1751.
    • (2003) Science , vol.300 , pp. 1749-1751
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4
  • 16
    • 0026492131 scopus 로고
    • Definition of the upstream efficiency element of the simian virus 40 late polyadenylation signal by using in vitro analyses
    • Schek, N, Cooke, C and Alwine, JC (1992). Definition of the upstream efficiency element of the simian virus 40 late polyadenylation signal by using in vitro analyses. Mol Cell Biol 12: 5386-5393.
    • (1992) Mol Cell Biol , vol.12 , pp. 5386-5393
    • Schek, N.1    Cooke, C.2    Alwine, J.C.3
  • 17
    • 0024457824 scopus 로고
    • Efficiency of utilization of the simian virus 40 late polyadenylation site: Effects of upstream sequences
    • Carswell, S and Alwine, JC (1989). Efficiency of utilization of the simian virus 40 late polyadenylation site: Effects of upstream sequences. Mol Cell Biol 9: 4248-4258.
    • (1989) Mol Cell Biol , vol.9 , pp. 4248-4258
    • Carswell, S.1    Alwine, J.C.2
  • 18
    • 0025965164 scopus 로고
    • The human immunodeficiency virus type 1 polyadenylylation signal: A 3′ long terminal repeat element upstream of the AAUAAA necessary for efficient polyadenylylation
    • Valsamakis, A, Zeichner, S, Carswell, S and Alwine, JC (1991). The human immunodeficiency virus type 1 polyadenylylation signal: A 3′ long terminal repeat element upstream of the AAUAAA necessary for efficient polyadenylylation. Proc Natl Acad Sci U S A 88: 2108-2112.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 2108-2112
    • Valsamakis, A.1    Zeichner, S.2    Carswell, S.3    Alwine, J.C.4
  • 19
    • 0026046955 scopus 로고
    • Sequences regulating temporal poly(A) site switching in the adenovirus major late transcription unit
    • DeZazzo, JD, Falck-Pedersen, E and Imperiale, MJ (1991). Sequences regulating temporal poly(A) site switching in the adenovirus major late transcription unit. Mol Cell Biol 11: 5977-5984.
    • (1991) Mol Cell Biol , vol.11 , pp. 5977-5984
    • DeZazzo, J.D.1    Falck-Pedersen, E.2    Imperiale, M.J.3
  • 20
    • 0026464672 scopus 로고
    • Upstream sequences and cap proximity in the regulation of polyadenylation in ground squirrel hepatitis virus
    • Cherrington, R, Russnak, R and Ganem, D (1992). Upstream sequences and cap proximity in the regulation of polyadenylation in ground squirrel hepatitis virus. J Virol 66: 7589-7596.
    • (1992) J Virol , vol.66 , pp. 7589-7596
    • Cherrington, R.1    Russnak, R.2    Ganem, D.3
  • 21
    • 0025323818 scopus 로고
    • Sequences 5′ to the polyadenylation signal mediate differential poly(A) site use in hepatitis B viruses
    • Russnak, R and Ganem, D (1990). Sequences 5′ to the polyadenylation signal mediate differential poly(A) site use in hepatitis B viruses. Genes Dev 4: 764-776.
    • (1990) Genes Dev , vol.4 , pp. 764-776
    • Russnak, R.1    Ganem, D.2
  • 22
    • 0026409222 scopus 로고
    • Regulation of polyadenylation in hepatitis B viruses: Stimulation by the upstream activating signal PS1 is orientation-dependent, distance-independent and additive
    • Russnak, RH (1991). Regulation of polyadenylation in hepatitis B viruses: Stimulation by the upstream activating signal PS1 is orientation-dependent, distance-independent and additive. Nucleic Acids Res 19: 6449-6456.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6449-6456
    • Russnak, R.H.1
  • 23
    • 0028339994 scopus 로고
    • Sequence elements upstream of the 3′ cleavage site confer substrate strength to the adenovirus L1 and L3 polyadenylation sites
    • Prescott, J and Falck-Pedersen, E (1994). Sequence elements upstream of the 3′ cleavage site confer substrate strength to the adenovirus L1 and L3 polyadenylation sites. Mol Cell Biol 14: 4682-4693.
    • (1994) Mol Cell Biol , vol.14 , pp. 4682-4693
    • Prescott, J.1    Falck-Pedersen, E.2
  • 24
    • 1442313922 scopus 로고    scopus 로고
    • Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase
    • Kaufmann, I, Martin, G, Friedlein, A, Langen, H and Keller, W (2004). Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. EMBO J 23: 616-626.
    • (2004) EMBO J , vol.23 , pp. 616-626
    • Kaufmann, I.1    Martin, G.2    Friedlein, A.3    Langen, H.4    Keller, W.5
  • 25
    • 3142585004 scopus 로고    scopus 로고
    • The prothrombin 3′ end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations
    • Danckwardt, S, Gehring, NH, Neu-Yilik G, Hundsdoerfer, P, Plforsich, M, Frede, U et al. (2004). The prothrombin 3′ end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations. Blood 104: 428-435.
    • (2004) Blood , vol.104 , pp. 428-435
    • Danckwardt, S.1    Gehring, N.H.2    Neu-Yilik, G.3    Hundsdoerfer, P.4    Plforsich, M.5    Frede, U.6
  • 26
    • 0029090065 scopus 로고    scopus 로고
    • (11995). Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved
    • Moreira, A, Wollerton, M, Monks, J and Proudfoot, NJ (11995). Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved. EMBO J 14: 3809-3819.
    • EMBO J , vol.14 , pp. 3809-3819
    • Moreira, A.1    Wollerton, M.2    Monks, J.3    Proudfoot, N.J.4
  • 27
    • 0032529163 scopus 로고    scopus 로고
    • The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3′ end formation by two distinct mechanisms
    • Moreira, A, Takagaki, Y, Brackenridge, S, Wollerton, M, Manley, JL and Proudfoot, NJ (1998). The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3′ end formation by two distinct mechanisms. Genes Dev 12: 2522-2534.
    • (1998) Genes Dev , vol.12 , pp. 2522-2534
    • Moreira, A.1    Takagaki, Y.2    Brackenridge, S.3    Wollerton, M.4    Manley, J.L.5    Proudfoot, N.J.6
  • 28
    • 0036207464 scopus 로고    scopus 로고
    • Improving the post-transcriptional aspects of lentiviral vectors
    • Hope, T (2002). Improving the post-transcriptional aspects of lentiviral vectors. Curr Top Microbiol Immunol 261: 179-189.
    • (2002) Curr Top Microbiol Immunol , vol.261 , pp. 179-189
    • Hope, T.1
  • 29
    • 0034322479 scopus 로고    scopus 로고
    • Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors
    • Schambach, A, Wodrich, H, Hildinger, M, Bohne, J, Krausslich, HG and Baum, C (2000). Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors. Mol Ther 2: 435-445.
    • (2000) Mol Ther , vol.2 , pp. 435-445
    • Schambach, A.1    Wodrich, H.2    Hildinger, M.3    Bohne, J.4    Krausslich, H.G.5    Baum, C.6
  • 30
    • 0028815108 scopus 로고
    • CPSF recognition of an HIV-1 mRNA 3′-processing enhancer: Multiple sequence contacts involved in poly(A) site definition
    • Gilmartin, GM, Fleming, ES, Oetjen, J and Graveley, BR (1995). CPSF recognition of an HIV-1 mRNA 3′-processing enhancer: Multiple sequence contacts involved in poly(A) site definition. Genes Dev 9: 72-83.
    • (1995) Genes Dev , vol.9 , pp. 72-83
    • Gilmartin, G.M.1    Fleming, E.S.2    Oetjen, J.3    Graveley, B.R.4
  • 31
    • 0028269622 scopus 로고
    • Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal
    • Lutz, CS and Alwine, JC (1994). Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal. Genes Dev 8: 576-586.
    • (1994) Genes Dev , vol.8 , pp. 576-586
    • Lutz, C.S.1    Alwine, J.C.2
  • 32
    • 0030024350 scopus 로고    scopus 로고
    • Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro
    • Lutz, CS, Murthy, KG, Schek, N, O'Connor, JP, Manley, JL and Alwine, JC (1996). Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes Dev 10: 325-337.
    • (1996) Genes Dev , vol.10 , pp. 325-337
    • Lutz, C.S.1    Murthy, K.G.2    Schek, N.3    O'Connor, J.P.4    Manley, J.L.5    Alwine, J.C.6
  • 33
    • 0026078053 scopus 로고
    • A dissection of the cauliflower mosaic virus polyadenylation signal
    • Sanfacon, H, Brodmann, P and Hohn, T (1991). A dissection of the cauliflower mosaic virus polyadenylation signal. Genes Dev 5 141-149.
    • (1991) Genes Dev , vol.5 , pp. 141-149
    • Sanfacon, H.1    Brodmann, P.2    Hohn, T.3
  • 34
    • 0032978733 scopus 로고    scopus 로고
    • R region sequences in the long terminal repeat of a murine retrovirus specifically increase expression of unspliced RNAs
    • Trubetskoy, AM, Okenquist, SA and Lenz, J (1999). R region sequences in the long terminal repeat of a murine retrovirus specifically increase expression of unspliced RNAs. J Virol 73: 3477-3483.
    • (1999) J Virol , vol.73 , pp. 3477-3483
    • Trubetskoy, A.M.1    Okenquist, S.A.2    Lenz, J.3
  • 35
    • 21044448037 scopus 로고    scopus 로고
    • Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking
    • Kustikova, O, Fehse, B, Modlich, U, Yang, M, Dullmann, J, Kamino, K et al. (2005). Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking. Science 308: 1171-1174.
    • (2005) Science , vol.308 , pp. 1171-1174
    • Kustikova, O.1    Fehse, B.2    Modlich, U.3    Yang, M.4    Dullmann, J.5    Kamino, K.6
  • 36
    • 33750624015 scopus 로고    scopus 로고
    • Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity
    • Modlich, U, Bohne, J, Schmidt, M, von Kalle, C, Knoss, S, Schambach, A et al. (2006). Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity. Blood 108: 2545-2553.
    • (2006) Blood , vol.108 , pp. 2545-2553
    • Modlich, U.1    Bohne, J.2    Schmidt, M.3    von Kalle, C.4    Knoss, S.5    Schambach, A.6
  • 37
    • 33745108790 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration
    • Montini, E, Cesana, D, Schmidt, M, Sanvito, F, Ponzoni, M, Bartholomae, C et al. (2006). Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration. Nat Biotechnol 24: 687-696.
    • (2006) Nat Biotechnol , vol.24 , pp. 687-696
    • Montini, E.1    Cesana, D.2    Schmidt, M.3    Sanvito, F.4    Ponzoni, M.5    Bartholomae, C.6
  • 38
    • 33646479480 scopus 로고    scopus 로고
    • Lentiviral vectors pseudotyped with murine ecotropic envelope: Increased biosafety and convenience in preclinical research
    • Schambach, A, Galla, M, Modlich, U, Will, E, Chandra, S, Reeves, L et al. (2006). Lentiviral vectors pseudotyped with murine ecotropic envelope: Increased biosafety and convenience in preclinical research. Exp Hematol 34: 588-592.
    • (2006) Exp Hematol , vol.34 , pp. 588-592
    • Schambach, A.1    Galla, M.2    Modlich, U.3    Will, E.4    Chandra, S.5    Reeves, L.6
  • 39
    • 2442647813 scopus 로고    scopus 로고
    • Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR
    • Winzen, R, Gowrishankar, G, Bollig, F, Redich, N, Resch, K and Holtmann, H (2004). Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR. Mol Cell Biol 24: 4835-4847.
    • (2004) Mol Cell Biol , vol.24 , pp. 4835-4847
    • Winzen, R.1    Gowrishankar, G.2    Bollig, F.3    Redich, N.4    Resch, K.5    Holtmann, H.6
  • 40
    • 10744220030 scopus 로고    scopus 로고
    • Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose
    • Li, Z, Schwieger, M, Lange, C, Kraunus, J, Sun, H, van den Akker, E et al. (2003). Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose. Exp Hematol 31: 1206-1214.
    • (2003) Exp Hematol , vol.31 , pp. 1206-1214
    • Li, Z.1    Schwieger, M.2    Lange, C.3    Kraunus, J.4    Sun, H.5    van den Akker, E.6


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