Pattern recognition receptor MDA5 modulates CD8+ T cell- dependent clearance of west nile virus from the central nervous system

Journal of Virology

Volumn 87, Issue 21, 2013, Pages 11401-11415

  Lazear, Helen M ^a   Pinto, Amelia K ^a   Ramos, Hilario J ^b   Vick, Sarah C ^a   Shrestha, Bimmi ^a   Suthar, Mehul S ^c   Gale Jr , Michael ^b   Diamond, Michael S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; PATTERN RECOGNITION RECEPTOR; PROTEIN MDA5; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CD8+ T LYMPHOCYTE; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; CYTOKINE RESPONSE; EX VIVO STUDY; FLAVIVIRUS INFECTION; IMMUNE DEFICIENCY; INFECTION SENSITIVITY; INOCULATION; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; SURVIVAL; T LYMPHOCYTE ACTIVATION; VIRAL CLEARANCE; VIRUS LOAD; VIRUS REPLICATION; WEST NILE FLAVIVIRUS;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; DEAD-BOX RNA HELICASES; DISEASE MODELS, ANIMAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, PATTERN RECOGNITION; SURVIVAL ANALYSIS; VIRAL LOAD; WEST NILE FEVER; WEST NILE VIRUS;

EID: 84886048507     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01403-13     Document Type: Article

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