RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice

Journal of Clinical Investigation

Volumn 121, Issue 4, 2011, Pages 1497-1507

  McCartney, Stephen A ^a   Vermi, William ^b   Lonardi, Silvia ^b   Rossini, Cristina ^b   Otero, Karel ^a   Calderon, Boris ^a   Gilfillan, Susan ^a   Diamond, Michael S ^a   Unanue, Emil R ^a   Colonna, Marco ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL DAMAGE; CONTROLLED STUDY; DIABETES MELLITUS; ENCEPHALOMYOCARDITIS VIRUS; ENCEPHALOMYOCARDITIS VIRUS INFECTION; HISTOPATHOLOGY; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS INFECTION; VIRUS STRAIN;

ANIMALS; CARDIOVIRUS INFECTIONS; DEAD-BOX RNA HELICASES; DIABETES MELLITUS, TYPE 1; ENCEPHALOMYOCARDITIS VIRUS; INSULIN-SECRETING CELLS; INTERFERON TYPE I; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; RNA, VIRAL; TOLL-LIKE RECEPTOR 3;

EID: 79953318392     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI44005     Document Type: Article

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