Leptin antagonist ameliorates chronic colitis in IL-10-/- mice

Immunobiology

Volumn 218, Issue 12, 2013, Pages 1439-1451

  Singh, Udai P ^a   Singh, Narendra P ^a   Guan, Hongbing ^a   Busbee, Brandon ^a   Price, Robert L ^a   Taub, Dennis D ^b   Mishra, Manoj K ^c   Fayad, Raja ^d   Nagarkatti, Mitzi ^a   Nagarkatti, Prakash S ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c ALABAMA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Antagonist; Crohn's disease (CD); Inflammation; Inflammatory bowel disease (IBD); Leptin; Pegylated; Ulcerative colitis (UC)

Indexed keywords

AMYLOID A PROTEIN; CD39 ANTIGEN; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON; HORMONE ANTAGONIST; INSULIN; INTERLEUKIN 10; LEPTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PEGYLATED LEPTIN ANTAGONIST; SMAD7 PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUCASIAN; CD4+ T LYMPHOCYTE; CHRONIC DISEASE; COLITIS; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG EFFECT; DRUG MECHANISM; ENTERITIS; ETHNIC DIFFERENCE; FEMALE; HISTOPATHOLOGY; HORMONE BLOOD LEVEL; HUMAN; HUMAN TISSUE; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; INSULIN BLOOD LEVEL; INTESTINAL PROTECTION; INTRACELLULAR SIGNALING; JEW; LYMPHOCYTE COUNT; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; NUTRITIONAL STATUS; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; WEIGHT GAIN;

ANTAGONIST; CROHN'S DISEASE (CD); INFLAMMATION; INFLAMMATORY BOWEL DISEASE (IBD); LEPTIN; PEGYLATED; ULCERATIVE COLITIS (UC);

ANIMALS; ANTIGENS, CD; APYRASE; BODY WEIGHT; CHRONIC DISEASE; COLITIS; DOWN-REGULATION; FEMALE; INSULIN; INTERLEUKIN-10; INTESTINAL MUCOSA; LEPTIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84885912790     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2013.04.020     Document Type: Article

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