Coriolus versicolor suppresses inflammatory bowel disease by inhibiting the expression of STAT1 and STAT6 associated with IFN-γ and IL-4 expression

Phytotherapy Research

Volumn 25, Issue 8, 2011, Pages 1257-1261

  Lim, Beong Ou ^a  

^a Konkuk University   (South Korea)

Author keywords

Coriolus versicolor; inflammatory bowel disease; inflammatory cytokines; STAT1 and 6

Indexed keywords

CORIOLUS VERSICOLOR EXTRACT; DEXTRAN SULFATE; DRINKING WATER; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; PLANT EXTRACT; STAT1 PROTEIN; STAT6 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; BODY WEIGHT; CLINICAL FEATURE; CONTROLLED STUDY; CORIOLUS VERSICOLOR; DRUG MECHANISM; ENTERITIS; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MESENTERY LYMPH NODE; MOUSE; MUSHROOM; NONHUMAN; ORGAN WEIGHT; PROTEIN EXPRESSION; SPLEEN; SYMPTOM; TISSUE LEVEL; ULCERATIVE COLITIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BODY WEIGHT; CORIOLACEAE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; INFLAMMATORY BOWEL DISEASES; INTERFERON-GAMMA; INTERLEUKIN-4; INTESTINES; MALE; MICE; MICE, INBRED BALB C; ORGAN SIZE; PLANT EXTRACTS; STAT1 TRANSCRIPTION FACTOR; STAT6 TRANSCRIPTION FACTOR;

MUS; TRAMETES VERSICOLOR;

EID: 80051688019     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3378     Document Type: Article

References (21)

1. Burnette WN,. 1981. 'Western blotting': electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem 112: 195-203.
2. Cooper HS, Murthy SN, Shah RS, Sedergran DJ,. 1993. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69: 238-249.
3. Darnell JE Jr, Kerr IM, Stark GR,. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1421. (Pubitemid 24217131)
4. Egger B, Bajaj-Elliot M, MacDonald TT, Inglin R, Eysselein VE, Buchler MW,. 2000. Characterisation of acute murine dextran sulfate colitis: cytokine profile and dose dependency. Digestion 62: 240-148.
5. Jackson L, Evers BM,. 2006. Chronic inflammation and pathogenesis of G1 and pancreatic cancers. Cancer Treatment Res 130: 39-65.
6. Kidd PM,. 2000. The use of mushroom glucans and proteoglycans in cancer treatment. Alternat Med Rev 5: 4-27. (Pubitemid 30132069)
7. La Sala A, Gadina M, Kelsall BL,. 2005. G(i) protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK. J Immunol 175: 2994-2999. (Pubitemid 41170517)
8. Lim BO,. 2003. Effects of wogonin, wogonoside, and 3,5,7,2′, 6′-pentahydroxyflavone on chemical mediator production in peritoneal exudate cells and immunoglobulin E of rat mesenteric lymph node lymphocytes. J Ethnopharmacol 84: 23-29. (Pubitemid 36034232)
9. Metcalfe DD,. 1991. Food allergy. Curr Opin Immunol 3: 881-886.
10. Mudter J, Neurath MF,. 2003. Mucosal T-cells: Mediators or guardians of inflammatory bowel disease? Curr Opin Gastroenterol 19: 343-349. (Pubitemid 36819787)
11. Murphy SNS, Cooper HS, Shim H, Shah RS, Ibrahim SA, Sedergran DJ,. 1993. Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporine. Digest Dis Sci 38: 1722-1734. (Pubitemid 23271431)
12. Podolsky DK,. 1991. Inflammatory bowel disease (1). N Engl J Med 325: 928-937.
13. Rengarajan J, Szabo SJ, Glimcher LH,. 2000. Transcriptional regulation of Th1/Th2 polarization. Immunol Today 21: 479-483.
14. Sampson HA, Metcalfe DD, 1992. Food allergies. J Am Med Assoc 268: 2840-2844.
15. Schreiber S, Heinig T, Panzer U, et al., 1995. Impaired response of activated mononuclear phagocytes to interleukin 4 in inflammatory bowel disease. Gastroenterology 108: 21-33.
16. Schreiber S, Rosenstiel P, Hampe J, et al., 2002. Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease. Gut 51: 379-385.
17. Shanahan F,. 2000. Nutrient tasting and signaling mechanisms in the gut. V. Mechanisms of immunologic sensation of intestinal contents. Am J Physiol Gastrointest Liver Physiol 278: 191-196.
18. Shanahan F,. 2001. Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics. Gastroenterology 120: 622-635. (Pubitemid 32171636)
19. Spencer JW,. 1999. Essential issues in complementary/alternative medicine. In Complementary/Alternative Medicine, An Evidence-based Approach, Spencer JW, and, Jacobs JJ, (eds). Mosby: St Louis, 3-36.
20. Strober W, Ludviksson BR, Fuss IJ,. 1998. The pathogenesis of mucosal inflammation in murine models of inflammatory bowel disease and Crohn disease. Ann Intern Med 128: 848-856. (Pubitemid 28267719)
21. Zhong Z, Wen Z, Darnell JE Jr. , 1994. STAT3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264: 95-98. (Pubitemid 24144493)