Topical antisense oligonucleotide therapy against LIX, an enterocyte-expressed CXC chemokine, reduces murine colitis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 289, Issue 6 52-6, 2005, Pages

  Kwon, John H ^a   Keates, Andrew C ^b   Anton, Pauline M ^b   Botero, Maria ^b   Goldsmith, Jeffrey D ^b   Kelly, Ciarán P ^b,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Chemokine; Colitis; Murine; Neutrophil

Indexed keywords

ALPHA CHEMOKINE; ANTISENSE OLIGONUCLEOTIDE; CYTOKINE; DEXTRAN; ENEMA; EPITHELIAL NEUTROPHIL ACTIVATING PEPTIDE 78; LIPOPOLYSACCHARIDE; LIX CHEMOKINE; SODIUM SULFATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON MUCOSA; CONTROLLED STUDY; DISEASE SEVERITY; DRUG ADMINISTRATION ROUTE; DRUG EFFICACY; ENTERITIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOREGULATION; IMMUNOSTIMULATION; INFLAMMATION; INTESTINE CELL; INTESTINE INJURY; INTRACOLONIC DRUG ADMINISTRATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TREATMENT OUTCOME; ULCERATIVE COLITIS;

ANIMALS; CELL LINE; CHEMOKINES, CXC; COLITIS; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; ENTEROCYTES; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE;

EID: 28444458521     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00073.2005     Document Type: Article

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