AICAR sustains J1 mouse embryonic stem cell self-renewal and pluripotency by regulating transcription factor and epigenetic modulator expression

Cellular Physiology and Biochemistry

Volumn 32, Issue 2, 2013, Pages 459-475

  Shi, Xiaoyan ^a   Wu, Yongyan ^a   Ai, Zhiying ^a   Liu, Xin ^a   Yang, Liping ^a   Du, Juan ^a   Shao, Jingjing ^a   Guo, Zekun ^a   Zhang, Yong ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Epigenetic; Gene expression; Pluripotency; Signal transduction; Small molecule

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; TRANSCRIPTION FACTOR; BONE MORPHOGENETIC PROTEIN; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; MITOGEN ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; DOWN REGULATION; EMBRYONIC STEM CELL; EPIGENETICS; GENE EXPRESSION; GENOME; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; CELL DIFFERENTIATION; CELL RENEWAL; CONTROLLED STUDY; DNA BINDING; DNA METHYLATION; GENE CONTROL; GENE EXPRESSION PROFILING; HISTONE MODIFICATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; EPIGENESIS, GENETIC; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MICE; PLURIPOTENT STEM CELLS; REAL-TIME POLYMERASE CHAIN REACTION; RIBONUCLEOTIDES; TRANSCRIPTION FACTORS;

EID: 84885625613     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000354451     Document Type: Article

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