Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression

Journal of Biological Chemistry

Volumn 285, Issue 12, 2010, Pages 9180-9189

  Zhang, Peilin ^a   Andrianakos, Rose ^a   Yang, Yang ^a   Liu, Chunming ^b   Lu, Wange ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; PROTEINS; TRANSCRIPTION;

BONE MORPHOGENETIC PROTEIN-4; EMBRYONIC STEM CELLS; KRUPPEL-LIKE FACTORS; LEUKEMIA INHIBITORY FACTORS; PLURIPOTENCY; PROMOTER REGION; SELF RENEWAL; SOMATIC CELLS;

CYTOLOGY;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 4; KRUPPEL LIKE FACTOR 4; LEUKEMIA INHIBITORY FACTOR; TRANSCRIPTION FACTOR NANOG; BMP4 PROTEIN, HUMAN; BMP4 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; KRUPPEL LIKE FACTOR; NANOG PROTEIN, HUMAN; NANOG PROTEIN, MOUSE; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE;

ARTICLE; CELL DIFFERENTIATION; CELL RENEWAL; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; METABOLISM; MOUSE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEUKEMIA INHIBITORY FACTOR; MICE; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 77950560406     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.077958     Document Type: Article

References (43)

1. Evans, M. J., and Kaufman, M. H. (1981) Nature 292, 154-156
2. Martin, G. R. (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 7634-7638
3. Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Schöler, H., and Smith, A. (1998) Cell 95, 379-391
4. Niwa, H., Miyazaki, J., and Smith, A. G. (2000) Nat. Genet. 24, 372-376
5. Ambrosetti, D. C., Basilico, C., and Dailey, L. (1997) Mol. Cell Biol. 17, 6321-6329
6. Avilion, A. A., Nicolis, S. K., Pevny, L. H., Perez, L., Vivian, N., and Lovell-Badge, R. (2003) Genes Dev. 17, 126-140
7. Yuan, H., Corbi, N., Basilico, C., and Dailey, L. (1995) Genes Dev. 9, 2635-2645
8. Chambers, I., Colby, D., Robertson, M., Nichols, J., Lee, S., Tweedie, S., and Smith, A. (2003) Cell 113, 643-655
9. Mitsui, K., Tokuzawa, Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K., Maruyama, M., Maeda, M., and Yamanaka, S. (2003) Cell 113, 631-642
10. Boyer, L. A., Lee, T. I., Cole, M. F., Johnstone, S. E., Levine, S. S., Zucker, J. P., Guenther, M. G., Kumar, R. M., Murray, H. L., Jenner, R. G., Gifford, D. K., Melton, D. A., Jaenisch, R., and Young, R. A. (2005) Cell 122, 947-956
11. Schuh, R., Aicher, W., Gaul, U., Côté, S., Preiss, A., Maier, D., Seifert, E., Nauber, U., Schröder, C., and Kemler, R. (1986) Cell 47, 1025-1032
12. Rowland, B. D., Bernards, R., and Peeper, D. S. (2005) Nat. Cell Biol. 7, 1074-1082
13. McConnell, B. B., Ghaleb, A. M., Nandan, M. O., and Yang, V. W. (2007) Bioessays 29, 946-946
14. Rowland, B. D., and Peeper, D. S. (2006) Nat. Rev. Cancer 6, 11-23
15. Chen, X., Johns, D. C., Geiman, D. E., Marban, E., Dang, D. T., Hamlin, G., Sun, R., and Yang, V. W. (2001) J. Biol. Chem. 276, 30423-30428
16. Shields, J. M., Christy, R. J., and Yang, V. W. (1996) J. Biol. Chem. 271, 20009-20017
17. Takahashi, K., and Yamanaka, S. (2006) Cell 126, 663-676
18. Wernig, M., Meissner, A., Foreman, R., Brambrink, T., Ku, M., Hochedlinger, K., Bernstein, B. E., and Jaenisch, R. (2007) Nature 448, 318-324
19. Yamanaka, S. (2007) Cell Stem Cell 1, 39-49
20. Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007) Cell 131, 861-872
21. Nakagawa, M., Koyanagi, M., Tanabe, K., Takahashi, K., Ichisaka, T., Aoi, T., Okita, K., Mochiduki, Y., Takizawa, N., and Yamanaka, S. (2008) Nat. Biotechnol. 26, 101-106
22. Wernig, M., Meissner, A., Cassady, J. P., and Jaenisch, R. (2008) Cell Stem Cell 2, 10-12
23. Bruce, S. J., Gardiner, B. B., Burke, L. J., Gongora, M. M., Grimmond, S. M., and Perkins, A. C. (2007) BMC Genomics 8, 365
24. Guo, G., Yang, J., Nichols, J., Hall, J. S., Eyres, I., Mansfield, W., and Smith, A. (2009) Development 136, 1063-1069
25. Smith, A. G., Heath, J. K., Donaldson, D. D., Wong, G. G., Moreau, J., Stahl, M., and Rogers, D. (1988) Nature 336, 688-690
26. Williams, R. L., Hilton, D. J., Pease, S., Willson, T. A., Stewart, C. L., Gearing, D. P., Wagner, E. F., Metcalf, D., Nicola, N. A., and Gough, N. M. (1988) Nature 336, 684-687
27. Ying, Q. L., Nichols, J., Chambers, I., and Smith, A. (2003) Cell 115, 281-292
28. Matsuda, T., Nakamura, T., Nakao, K., Arai, T., Katsuki, M., Heike, T., and Yokota, T. (1999) EMBO J. 18, 4261-4269
29. Niwa, H., Burdon, T., Chambers, I., and Smith, A. (1998) Genes Dev. 12, 2048-2060
30. Rodda, D. J., Chew, J. L., Lim, L. H., Loh, Y. H., Wang, B., Ng, H. H., and Robson, P. (2005) J. Biol. Chem. 280, 24731-24737
31. Kidder, B. L., Yang, J., and Palmer, S. (2008) PLoS One 3, e3932
32. Bourillot, P. Y., Aksoy, I., Schreiber, V., Wianny, F., Schulz, H., Hummel, O., Hubner, N., and Savatier, P. (2009) Stem Cells 27, 1760-1771
33. Hall, J., Guo, G., Wray, J., Eyres, I., Nichols, J., Grotewold, L., Morfopoulou, S., Humphreys, P., Mansfield, W., Walker, R., Tomlinson, S., and Smith, A. (2009) Cell Stem Cell 5, 597-609
34. Niwa, H., Ogawa, K., Shimosato, D., and Adachi, K. (2009) Nature 460, 118-122
35. Wei, Z., Yang, Y., Zhang, P., Andrianakos, R., Hasegawa, K., Lyu, J., Chen, X., Bai, G., Liu, C., Pera, M., and Lu, W. (2009) Stem Cells 27, 2969-2978
36. Orkin, S. H. (2005) Cell 122, 828-830
37. Masui, S., Nakatake, Y., Toyooka, Y., Shimosato, D., Yagi, R., Takahashi, K., Okochi, H., Okuda, A., Matoba, R., Sharov, A. A., Ko, M. S., and Niwa, H. (2007) Nat. Cell Biol. 9, 625-635
38. Odom, D. T., Dowell, R. D., Jacobsen, E. S., Nekludova, L., Rolfe, P. A., Danford, T. W., Gifford, D. K., Fraenkel, E., Bell, G. I., and Young, R. A. (2006) Mol. Syst. Biol. 2, 2006.0017
39. Kim, J., Chu, J., Shen, X., Wang, J., and Orkin, S. H. (2008) Cell 132, 1049-1061
40. Jiang, J., Chan, Y. S., Loh, Y. H., Cai, J., Tong, G. Q., Lim, C. A., Robson, P., Zhong, S., and Ng, H. H. (2008) Nat. Cell Biol. 10, 353-360
41. Ema, M., Mori, D., Niwa, H., Hasegawa, Y., Yamanaka, Y., Hitoshi, S., Mimura, J., Kawabe, Y., Hosoya, T., Morita, M., Shimosato, D., Uchida, K., Suzuki, N., Yanagisawa, J., Sogawa, K., Rossant, J., Yamamoto, M., Takahashi, S., and Fujii-Kuriyama, Y. (2008) Cell Stem Cell 3, 555-567
42. Bruce, S. J., Gardiner, B. B., Burke, L. J., Gongora, M. M., Grimmond, S. M., and Perkins, A. C. (2007) BMC Genomics 8, 365
43. Nakatake, Y., Fukui, N., Iwamatsu, Y., Masui, S., Takahashi, K., Yagi, R., Yagi, K., Miyazaki, J., Matoba, R., Ko, M. S., and Niwa, H. (2006) Mol. Cell Biol. 26, 7772-7782