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Volumn 24, Issue 9, 2006, Pages 1998-2006

Lefty at the crossroads of "stemness" and differentiative events

Author keywords

Embryonic stem cells; Endometrial bleeding associated factor; Lefty; Review

Indexed keywords

EPIDERMAL GROWTH FACTOR; LEUKEMIA INHIBITORY FACTOR; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN CRIPTO; PROTEIN CRYPTIC; PROTEIN FRL 1; PROTEIN LEFTY; PROTEIN NODAL; RECEPTOR; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 33749175620     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2006-0075     Document Type: Short Survey
Times cited : (98)

References (76)
  • 1
    • 2342450859 scopus 로고    scopus 로고
    • Transcriptome analysis of mouse stem cells and early embryos
    • Sharov AA, Piao Y, Matoba R et al. Transcriptome analysis of mouse stem cells and early embryos. PLoS Biol 2003;1:E74.
    • (2003) PLoS Biol , vol.1
    • Sharov, A.A.1    Piao, Y.2    Matoba, R.3
  • 2
    • 0037130961 scopus 로고    scopus 로고
    • A stem cell molecular signature
    • Ivanova NB, Dimos JT, Schaniel C et al. A stem cell molecular signature. Science 2002;298:601-604.
    • (2002) Science , vol.298 , pp. 601-604
    • Ivanova, N.B.1    Dimos, J.T.2    Schaniel, C.3
  • 3
    • 0037131389 scopus 로고    scopus 로고
    • "Stemness": Transcriptional profiling of embryonic and adult stem cells
    • Ramalho-Santos M, Yoon S, Matsuzaki Y et al. "Stemness": Transcriptional profiling of embryonic and adult stem cells. Science 2002;298:597-600.
    • (2002) Science , vol.298 , pp. 597-600
    • Ramalho-Santos, M.1    Yoon, S.2    Matsuzaki, Y.3
  • 4
    • 0242272438 scopus 로고    scopus 로고
    • Comment on "'Stemness': Transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature"
    • Fortunel NO, Otu HH, Ng HH et al. Comment on "'Stemness': Transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature". Science 2003;302:393.
    • (2003) Science , vol.302 , pp. 393
    • Fortunel, N.O.1    Otu, H.H.2    Ng, H.H.3
  • 5
    • 0041560908 scopus 로고    scopus 로고
    • Molecular signature of human embryonic stem cells and its comparison with the mouse
    • Sato N, Sanjuan IM, Heke M et al. Molecular signature of human embryonic stem cells and its comparison with the mouse. Dev Biol 2003;260:404-413.
    • (2003) Dev Biol , vol.260 , pp. 404-413
    • Sato, N.1    Sanjuan, I.M.2    Heke, M.3
  • 6
    • 0345687164 scopus 로고    scopus 로고
    • Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors
    • Sperger JM, Chen X, Draper JS et al. Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. Proc Natl Acad Sci U S A 2003;100:13350-13355.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13350-13355
    • Sperger, J.M.1    Chen, X.2    Draper, J.S.3
  • 7
    • 0346250854 scopus 로고    scopus 로고
    • The transcriptome profile of human embryonic stem cells as defined by SAGE
    • Richards M, Tan SP, Tan JH et al. The transcriptome profile of human embryonic stem cells as defined by SAGE. STEM CELLS 2004;22:51-64.
    • (2004) Stem Cells , vol.22 , pp. 51-64
    • Richards, M.1    Tan, S.P.2    Tan, J.H.3
  • 8
    • 28444495872 scopus 로고    scopus 로고
    • Primary differentiation in the human blastocyst: Comparative molecular portraits of inner cell mass and trophectoderm cells
    • Adjaye J, Huntriss J, Herwig R et al. Primary differentiation in the human blastocyst: Comparative molecular portraits of inner cell mass and trophectoderm cells. STEM CELLS 2005;23:1514-1525.
    • (2005) Stem Cells , vol.23 , pp. 1514-1525
    • Adjaye, J.1    Huntriss, J.2    Herwig, R.3
  • 9
    • 19944386909 scopus 로고    scopus 로고
    • Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies
    • Dvash T, Mayshar Y, Darr H et al. Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies. Hum Reprod 2004;19:2875-2883.
    • (2004) Hum Reprod , vol.19 , pp. 2875-2883
    • Dvash, T.1    Mayshar, Y.2    Darr, H.3
  • 10
    • 13744252631 scopus 로고    scopus 로고
    • Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state
    • Wei CL, Miura T, Robson P et al. Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. STEM CELLS 2005;23:166-185.
    • (2005) Stem Cells , vol.23 , pp. 166-185
    • Wei, C.L.1    Miura, T.2    Robson, P.3
  • 11
    • 0033961920 scopus 로고    scopus 로고
    • Human embryonic stem cell and embryonic germ cell lines
    • Thomson JA, Odorico JS. Human embryonic stem cell and embryonic germ cell lines. Trends Biotechnol 2000;18:53-57.
    • (2000) Trends Biotechnol , vol.18 , pp. 53-57
    • Thomson, J.A.1    Odorico, J.S.2
  • 12
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of WNT signaling by a pharmacological GSK-3-specific inhibitor
    • Sato N, Meijer L, Skaltsounis L et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of WNT signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004;10:55-63.
    • (2004) Nat Med , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3
  • 13
    • 0030875352 scopus 로고    scopus 로고
    • Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells
    • Boeuf H, Hauss C, Graeve FD et al. Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells. J Cell Biol 1997;138:1207-1217.
    • (1997) J Cell Biol , vol.138 , pp. 1207-1217
    • Boeuf, H.1    Hauss, C.2    Graeve, F.D.3
  • 14
    • 0033517123 scopus 로고    scopus 로고
    • STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
    • Matsuda T, Nakamura T, Nakao K et al. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 1999;18:4261-4269.
    • (1999) EMBO J , vol.18 , pp. 4261-4269
    • Matsuda, T.1    Nakamura, T.2    Nakao, K.3
  • 15
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa H, Burdon T, Chambers I et al. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 1998;12:2048-2060.
    • (1998) Genes Dev , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3
  • 16
    • 28444480969 scopus 로고    scopus 로고
    • Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells
    • Sekkai D, Gruel G, Herry M et al. Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells. STEM CELLS 2005;23:1634-1642.
    • (2005) Stem Cells , vol.23 , pp. 1634-1642
    • Sekkai, D.1    Gruel, G.2    Herry, M.3
  • 17
    • 0031935539 scopus 로고    scopus 로고
    • Stra3/Lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily
    • Oulad-Abdelghani M, Chazaud C, Bouillet P et al. Stra3/Lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily. Int J Dev Biol 1998;42:23-32.
    • (1998) Int J Dev Biol , vol.42 , pp. 23-32
    • Oulad-Abdelghani, M.1    Chazaud, C.2    Bouillet, P.3
  • 18
    • 27644486756 scopus 로고    scopus 로고
    • Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
    • Vallier L, Alexander M, Pedersen RA. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J Cell Sci 2005;118:4495-4509.
    • (2005) J Cell Sci , vol.118 , pp. 4495-4509
    • Vallier, L.1    Alexander, M.2    Pedersen, R.A.3
  • 19
    • 0033197552 scopus 로고    scopus 로고
    • Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation
    • Meno C, Gritsman K, Ohishi S et al. Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Mol Cell 1999;4:287-298.
    • (1999) Mol Cell , vol.4 , pp. 287-298
    • Meno, C.1    Gritsman, K.2    Ohishi, S.3
  • 20
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003;113:685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 21
    • 0033564195 scopus 로고    scopus 로고
    • Determination of left/right asymmetric expression of Nodal by a left side-specific enhancer with sequence similarity to a Lefty-2 enhancer
    • Adachi H, Saijoh Y, Mochida K et al. Determination of left/right asymmetric expression of Nodal by a left side-specific enhancer with sequence similarity to a Lefty-2 enhancer. Genes Dev 1999;13:1589-1600.
    • (1999) Genes Dev , vol.13 , pp. 1589-1600
    • Adachi, H.1    Saijoh, Y.2    Mochida, K.3
  • 22
    • 0033082264 scopus 로고    scopus 로고
    • Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of Lefty-1 and Lefty-2
    • Saijoh Y, Adachi H, Mochida K et al. Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of Lefty-1 and Lefty-2. Genes Dev 1999;13:259-269.
    • (1999) Genes Dev , vol.13 , pp. 259-269
    • Saijoh, Y.1    Adachi, H.2    Mochida, K.3
  • 23
    • 0033969935 scopus 로고    scopus 로고
    • Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2
    • Saijoh Y, Adachi H, Sakuma R et al. Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol Cell 2000;5:35-47.
    • (2000) Mol Cell , vol.5 , pp. 35-47
    • Saijoh, Y.1    Adachi, H.2    Sakuma, R.3
  • 24
    • 0031011733 scopus 로고    scopus 로고
    • Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding
    • Kothapalli R, Buyuksal I, Wu S-Q et al. Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding. J Clin Invest 1997;99:2342-2350.
    • (1997) J Clin Invest , vol.99 , pp. 2342-2350
    • Kothapalli, R.1    Buyuksal, I.2    Wu, S.-Q.3
  • 25
    • 0033361929 scopus 로고    scopus 로고
    • Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development
    • Kosaki K, Bassi MT, Kosaki R et al. Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. Am J Hum Genet 1999;64:712-721.
    • (1999) Am J Hum Genet , vol.64 , pp. 712-721
    • Kosaki, K.1    Bassi, M.T.2    Kosaki, R.3
  • 26
    • 0034898325 scopus 로고    scopus 로고
    • Morpholino knock-down of antivin1 and antivin2 upregulates nodal signaling
    • Agathon A, Thisse B, Thisse C. Morpholino knock-down of antivin1 and antivin2 upregulates nodal signaling. Genesis 2001;30:178-182.
    • (2001) Genesis , vol.30 , pp. 178-182
    • Agathon, A.1    Thisse, B.2    Thisse, C.3
  • 27
    • 6744229777 scopus 로고    scopus 로고
    • Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes
    • Yashiro K, Saijoh Y, Sakuma R et al. Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes. Genes Cells 2000;5:343-357.
    • (2000) Genes Cells , vol.5 , pp. 343-357
    • Yashiro, K.1    Saijoh, Y.2    Sakuma, R.3
  • 28
    • 0029932564 scopus 로고    scopus 로고
    • Left-right asymmetric expression of the TGF-beta family member Lefty in mouse embryos
    • Meno C, Saijoh Y, Fujii H et al. Left-right asymmetric expression of the TGF-beta family member Lefty in mouse embryos. Nature 1996;381:151-155.
    • (1996) Nature , vol.381 , pp. 151-155
    • Meno, C.1    Saijoh, Y.2    Fujii, H.3
  • 29
    • 0035877662 scopus 로고    scopus 로고
    • Lefty proteins exhibit unique processing and activate the MAPK pathway
    • Ulloa L, Creemers JW, Roy S et al. Lefty proteins exhibit unique processing and activate the MAPK pathway. J Biol Chem 2001;276:21387-21396.
    • (2001) J Biol Chem , vol.276 , pp. 21387-21396
    • Ulloa, L.1    Creemers, J.W.2    Roy, S.3
  • 30
    • 0031196157 scopus 로고    scopus 로고
    • Two closely-related left-right asymmetrically expressed genes, Lefty-1 and Lefty-2: Their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos
    • Meno C, Ito Y, Saijoh Y et al. Two closely-related left-right asymmetrically expressed genes, Lefty-1 and Lefty-2: Their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos Genes Cells 1997;2:513-524.
    • (1997) Genes Cells , vol.2 , pp. 513-524
    • Meno, C.1    Ito, Y.2    Saijoh, Y.3
  • 31
    • 0024245022 scopus 로고    scopus 로고
    • Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
    • Smith AG, Heath JK, Donaldson DD et al. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 1998;336:688-690.
    • (1998) Nature , vol.336 , pp. 688-690
    • Smith, A.G.1    Heath, J.K.2    Donaldson, D.D.3
  • 32
    • 0025319004 scopus 로고
    • New type of POU domain in germ line-specific protein Oct-4
    • Schöler HR, Ruppert S, Suzuki N et al. New type of POU domain in germ line-specific protein Oct-4. Nature 1990;344:435-439.
    • (1990) Nature , vol.344 , pp. 435-439
    • Schöler, H.R.1    Ruppert, S.2    Suzuki, N.3
  • 33
    • 0025352402 scopus 로고
    • A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
    • Rosner MH, Vigano MA, Ozato K et al. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 1990;345:686-692.
    • (1990) Nature , vol.345 , pp. 686-692
    • Rosner, M.H.1    Vigano, M.A.2    Ozato, K.3
  • 34
    • 0025060177 scopus 로고
    • A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells
    • Okamoto K, Okazawa H, Okuda A et al. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 1990;60:461-472.
    • (1990) Cell , vol.60 , pp. 461-472
    • Okamoto, K.1    Okazawa, H.2    Okuda, A.3
  • 35
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000;24:372-376.
    • (2000) Nat Genet , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 36
    • 33644698339 scopus 로고    scopus 로고
    • WNT/PCP signaling pathway and human cancer
    • (review)
    • Katoh M. WNT/PCP signaling pathway and human cancer (review). Oncol Rep 2005;14:1583-1588.
    • (2005) Oncol Rep , vol.14 , pp. 1583-1588
    • Katoh, M.1
  • 37
    • 0346875916 scopus 로고    scopus 로고
    • GSK-3-selective inhibitors derived from Tyrian purple indirubins
    • Meijer L, Skaltsounis AL, Magiatis P et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol 2003;10:1255-1266.
    • (2003) Chem Biol , vol.10 , pp. 1255-1266
    • Meijer, L.1    Skaltsounis, A.L.2    Magiatis, P.3
  • 38
    • 0029142976 scopus 로고
    • Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development
    • Cserjesi P, Brown D, Lyons GE et al Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development. Dev Biol 1995;170:664-678.
    • (1995) Dev Biol , vol.170 , pp. 664-678
    • Cserjesi, P.1    Brown, D.2    Lyons, G.E.3
  • 39
    • 0028879331 scopus 로고
    • Expression of Cdx-2 in the mouse embryo and placenta: Possible role in patterning of the extra-embryonic membranes
    • Beck F, Erler T, Russell A et al. Expression of Cdx-2 in the mouse embryo and placenta: Possible role in patterning of the extra-embryonic membranes. Dev Dyn 1995;204:219-227.
    • (1995) Dev Dyn , vol.204 , pp. 219-227
    • Beck, F.1    Erler, T.2    Russell, A.3
  • 40
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of WNT signaling through beta-catenin
    • Moon RT, Bowerman B, Boutros M et al. The promise and perils of WNT signaling through beta-catenin. Science 2002;296:1644-1646.
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3
  • 41
    • 0037309239 scopus 로고    scopus 로고
    • You WNT some, you lose some: Oncogenes in the WNT signaling pathway
    • van Es JH, Barker, N, Clevers H. You WNT some, you lose some: Oncogenes in the WNT signaling pathway. Curr Opin Genet Dev 2003;13:28-33.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 28-33
    • Van Es, J.H.1    Barker, N.2    Clevers, H.3
  • 42
    • 7244240749 scopus 로고    scopus 로고
    • Expression of Nodal, Lefty-a, and Lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3
    • Besser D. Expression of Nodal, Lefty-a, and Lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3 J Biol Chem 2004;279:45076-45084.
    • (2004) J Biol Chem , vol.279 , pp. 45076-45084
    • Besser, D.1
  • 43
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein PS, Melton DA. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A 1996;93:8455-8459.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 44
    • 0030725756 scopus 로고    scopus 로고
    • Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
    • Nakayama K. Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem J 1997;327:625-635.
    • (1997) Biochem J , vol.327 , pp. 625-635
    • Nakayama, K.1
  • 45
    • 0036240683 scopus 로고    scopus 로고
    • Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion
    • Sakuma R, Ohnishi Yi Y, Meno C et al. Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion. Genes Cells 2002;7:401-412.
    • (2002) Genes Cells , vol.7 , pp. 401-412
    • Sakuma, R.1    Ohnishi Yi, Y.2    Meno, C.3
  • 46
    • 27844557347 scopus 로고    scopus 로고
    • Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and Lefty processing
    • Tang M, Mikhailik A, Pauli I et al. Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and Lefty processing. Endocrinology 2005;146:5313-5320.
    • (2005) Endocrinology , vol.146 , pp. 5313-5320
    • Tang, M.1    Mikhailik, A.2    Pauli, I.3
  • 47
    • 0032943366 scopus 로고    scopus 로고
    • Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction
    • Thisse C, Thisse B. Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction. Development 1999;126:229-240.
    • (1999) Development , vol.126 , pp. 229-240
    • Thisse, C.1    Thisse, B.2
  • 48
    • 0027251256 scopus 로고
    • A structural superfamily of growth factors containing a cystine knot motif
    • McDonald NQ, Hendrickson WA. A structural superfamily of growth factors containing a cystine knot motif. Cell 1993;73:421-424.
    • (1993) Cell , vol.73 , pp. 421-424
    • McDonald, N.Q.1    Hendrickson, W.A.2
  • 49
    • 0027401489 scopus 로고
    • GDF-3 and GDF-9: Two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines
    • McPherron AC, Lee SJ. GDF-3 and GDF-9: Two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines. J Biol Chem 1993;268:3444-3449.
    • (1993) J Biol Chem , vol.268 , pp. 3444-3449
    • McPherron, A.C.1    Lee, S.J.2
  • 50
    • 0345255908 scopus 로고    scopus 로고
    • Nodal signaling in vertebrate development
    • Schier AF. Nodal signaling in vertebrate development. Annu Rev Cell Dev Biol 2003;19:589-621.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 589-621
    • Schier, A.F.1
  • 51
    • 1842762249 scopus 로고    scopus 로고
    • Two modes by which Lefty proteins inhibit Nodal signaling
    • Chen C, Shen MM. Two modes by which Lefty proteins inhibit Nodal signaling. Curr Biol 2004;14:618-624.
    • (2004) Curr Biol , vol.14 , pp. 618-624
    • Chen, C.1    Shen, M.M.2
  • 52
    • 0034719512 scopus 로고    scopus 로고
    • Nodal signalling in vertebrate development
    • Schier AF, Shen MM. Nodal signalling in vertebrate development. Nature 2000;403:385-389.
    • (2000) Nature , vol.403 , pp. 385-389
    • Schier, A.F.1    Shen, M.M.2
  • 53
    • 0034237708 scopus 로고    scopus 로고
    • The EGF-CFC gene family in vertebrate development
    • Shen MM, Schier AF. The EGF-CFC gene family in vertebrate development. Trends Genet 2000;16:303-309.
    • (2000) Trends Genet , vol.16 , pp. 303-309
    • Shen, M.M.1    Schier, A.F.2
  • 54
    • 32244439642 scopus 로고    scopus 로고
    • The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo
    • Chen C, Ware SM, Sato A et al. The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo. Development 2006;133:319-329.
    • (2006) Development , vol.133 , pp. 319-329
    • Chen, C.1    Ware, S.M.2    Sato, A.3
  • 55
    • 0033568520 scopus 로고    scopus 로고
    • Cripto-1 induces phosphatidylinositol 3′-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells
    • Ebert AD, Wechselberger C, Frank S et al. Cripto-1 induces phosphatidylinositol 3′-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells. Cancer Res 1999;59:4502-4505.
    • (1999) Cancer Res , vol.59 , pp. 4502-4505
    • Ebert, A.D.1    Wechselberger, C.2    Frank, S.3
  • 56
    • 0036210652 scopus 로고    scopus 로고
    • Cripto-1 activates Nodaland ALK4-dependent and -independent signaling pathways in mammary epithelial Cells
    • Bianco C, Adkins HB, Wechselberger C et al. Cripto-1 activates Nodaland ALK4-dependent and -independent signaling pathways in mammary epithelial Cells. Mol Cell Biol 2002;22:2586-2597.
    • (2002) Mol Cell Biol , vol.22 , pp. 2586-2597
    • Bianco, C.1    Adkins, H.B.2    Wechselberger, C.3
  • 57
    • 19344369929 scopus 로고    scopus 로고
    • Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors
    • Cheng SK, Olale F, Brivanlou AH et al. Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. PLoS Biol 2004;2:E30.
    • (2004) PLoS Biol , vol.2
    • Cheng, S.K.1    Olale, F.2    Brivanlou, A.H.3
  • 58
    • 0028180752 scopus 로고
    • A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
    • Conlon FL, Lyons KM, Takaesu N et al. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development 1994;120:1919-1928.
    • (1994) Development , vol.120 , pp. 1919-1928
    • Conlon, F.L.1    Lyons, K.M.2    Takaesu, N.3
  • 59
    • 0032493876 scopus 로고    scopus 로고
    • Lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal
    • Meno C, Shimono A, Saijoh Y et al. Lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell 1998;94:287-297.
    • (1998) Cell , vol.94 , pp. 287-297
    • Meno, C.1    Shimono, A.2    Saijoh, Y.3
  • 60
    • 0036250574 scopus 로고    scopus 로고
    • Establishment of vertebrate left-right asymmetry
    • Hamada H, Meno C, Watanabe D et al. Establishment of vertebrate left-right asymmetry. Nat Rev Genet 2002;3:103-113.
    • (2002) Nat Rev Genet , vol.3 , pp. 103-113
    • Hamada, H.1    Meno, C.2    Watanabe, D.3
  • 61
    • 16244400050 scopus 로고    scopus 로고
    • TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • James D, Levine AJ, Besser D et al. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 2005;132:1273-1282.
    • (2005) Development , vol.132 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3
  • 62
    • 0037164735 scopus 로고    scopus 로고
    • Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation
    • Branford WW, Yost HJ. Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation. Curr Biol 2002;12:2136-2141.
    • (2002) Curr Biol , vol.12 , pp. 2136-2141
    • Branford, W.W.1    Yost, H.J.2
  • 63
    • 0026285560 scopus 로고
    • Development of handed body asymmetry in mammals
    • Brown NA, McCarthy A, Wolpert L. Development of handed body asymmetry in mammals. Ciba Found Symp 1991;162:182-201.
    • (1991) Ciba Found Symp , vol.162 , pp. 182-201
    • Brown, N.A.1    McCarthy, A.2    Wolpert, L.3
  • 64
    • 0025960648 scopus 로고
    • Evidence for an adrenergic mechanism in the control of body asymmetry
    • Fujinaga M, Baden JM. Evidence for an adrenergic mechanism in the control of body asymmetry. Dev Biol 1991;143:203-205.
    • (1991) Dev Biol , vol.143 , pp. 203-205
    • Fujinaga, M.1    Baden, J.M.2
  • 65
    • 0025744964 scopus 로고
    • Critical period of rat development when sidedness of asymmetric body structures is determined
    • Fujinaga M, Baden JM. Critical period of rat development when sidedness of asymmetric body structures is determined. Teratology 1991;44:453-462.
    • (1991) Teratology , vol.44 , pp. 453-462
    • Fujinaga, M.1    Baden, J.M.2
  • 66
    • 0026305132 scopus 로고
    • Development of the left-right axis in amphibians
    • Yost HJ. Development of the left-right axis in amphibians. Ciba Found Symp 1991;162:165-176.
    • (1991) Ciba Found Symp , vol.162 , pp. 165-176
    • Yost, H.J.1
  • 67
    • 0026561723 scopus 로고
    • Regulation of vertebrate left-right asymmetries by extracellular matrix
    • Yost HJ. Regulation of vertebrate left-right asymmetries by extracellular matrix. Nature 1992;357:496-497.
    • (1992) Nature , vol.357 , pp. 496-497
    • Yost, H.J.1
  • 68
    • 0029089617 scopus 로고
    • Molecular pathway determining left-right asymmetry in chick embryogenesis
    • Levin M, Johnson RL, Stern CD et al. Molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 1995;82:803-814.
    • (1995) Cell , vol.82 , pp. 803-814
    • Levin, M.1    Johnson, R.L.2    Stern, C.D.3
  • 69
    • 0034456460 scopus 로고    scopus 로고
    • Discovery of new inducible genes in in vitro decidualized human endometrial stromal cells using microarray technology
    • Popovici RM, Kao LC, Giudice LC. Discovery of new inducible genes in in vitro decidualized human endometrial stromal cells using microarray technology. Endocrinology 2000;141:3510-3513.
    • (2000) Endocrinology , vol.141 , pp. 3510-3513
    • Popovici, R.M.1    Kao, L.C.2    Giudice, L.C.3
  • 70
    • 0346109672 scopus 로고    scopus 로고
    • Gene induction and categorical reprogramming during in vitro human endometrial fibroblast decidualization
    • Brar AK, Handwerger S, Kessler CA et al. Gene induction and categorical reprogramming during in vitro human endometrial fibroblast decidualization. Physiol Genomics 2001;7:135-148.
    • (2001) Physiol Genomics , vol.7 , pp. 135-148
    • Brar, A.K.1    Handwerger, S.2    Kessler, C.A.3
  • 71
    • 18744378064 scopus 로고    scopus 로고
    • Lefty is expressed in mouse endometrium in estrous cycle and peri-implantation period
    • Tang M, Xu Y, Julian J et al. Lefty is expressed in mouse endometrium in estrous cycle and peri-implantation period. Hum Reprod 2005;20:872-880.
    • (2005) Hum Reprod , vol.20 , pp. 872-880
    • Tang, M.1    Xu, Y.2    Julian, J.3
  • 72
    • 27844557347 scopus 로고    scopus 로고
    • Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and Lefty processing
    • Tang M, Mikhailik A, Pauli I et al. Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and Lefty processing. Endocrinology 2005;46:5313-5320.
    • (2005) Endocrinology , vol.46 , pp. 5313-5320
    • Tang, M.1    Mikhailik, A.2    Pauli, I.3
  • 73
    • 14044257952 scopus 로고    scopus 로고
    • Requirement for proprotein convertase 5/6 during decidualization of human endometrial stromal cells in vitro
    • Okada H, Nie G, Salamonsen LA. Requirement for proprotein convertase 5/6 during decidualization of human endometrial stromal cells in vitro. J Clin Endocrinol Metab 2005;90:1028-1034.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1028-1034
    • Okada, H.1    Nie, G.2    Salamonsen, L.A.3
  • 74
    • 0030768885 scopus 로고    scopus 로고
    • Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation
    • Rancourt SL, Rancourt DE. Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation. Dev Genet 1997;21:75-81.
    • (1997) Dev Genet , vol.21 , pp. 75-81
    • Rancourt, S.L.1    Rancourt, D.E.2
  • 75
    • 0036184237 scopus 로고    scopus 로고
    • Subtilisin proprotein convertase-6 expression in the mouse uterus during implantation and artificially induced decidualization
    • Wong BS, Liu S, Schultz GA et al. Subtilisin proprotein convertase-6 expression in the mouse uterus during implantation and artificially induced decidualization. Mol Reprod Dev. 2002;61:2005;453-459.
    • (2002) Mol Reprod Dev , vol.61 , Issue.2005 , pp. 453-459
    • Wong, B.S.1    Liu, S.2    Schultz, G.A.3
  • 76
    • 27144503634 scopus 로고    scopus 로고
    • Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development
    • St. Germain C, Croissandeau G, Mayne J et al. Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development. Mol Reprod Dev 2005;72:483-493.
    • (2005) Mol Reprod Dev , vol.72 , pp. 483-493
    • St. Germain, C.1    Croissandeau, G.2    Mayne, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.