BMP induces cochlin expression to facilitate self-renewal and suppress neural differentiation of mouse embryonic stem cells

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8053-8060

  Zhang, Jianping ^a   Fei, Teng ^a   Li, Zhongwei ^a   Zhu, Gaoyang ^a   Wang, Lu ^a   Chen, Ye Guang ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENTIATED CELLS; DOWNSTREAM TARGET; INHIBITORY EFFECT; MOUSE EMBRYONIC STEM CELLS; NEURAL DIFFERENTIATIONS; OVER-EXPRESSION; TARGET GENES; UP-REGULATION;

CELL SIGNALING; GENE EXPRESSION;

MAMMALS;

BONE MORPHOGENETIC PROTEIN; COCHLIN; MITOGEN ACTIVATED PROTEIN KINASE; SMAD1 PROTEIN; SMAD4 PROTEIN; SMAD5 PROTEIN;

ANIMAL CELL; ARTICLE; CELL RENEWAL; COCH GENE; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC MARKER; HUMAN; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SOMATIC CELL; UPREGULATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CONSENSUS SEQUENCE; EMBRYONIC STEM CELLS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; NEURONS; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84875465266     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.433995     Document Type: Article

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