Cdk1 is required for the self-renewal of mouse embryonic stem cells

Journal of Cellular Biochemistry

Volumn 112, Issue 3, 2011, Pages 942-948

  Zhang, Wei Wei ^a   Zhang, Xiao Jie ^a   Liu, Hui Xian ^a   Chen, Jie ^a   Ren, Yong Hong ^b   Huang, Deng Gao ^a   Zou, Xiang Hong ^a,c   Xiao, Wei ^a,d  

^a CAPITAL NORMAL UNIVERSITY   (China)

^b CapitalBio Corporation   (China)

^c OHIO STATE UNIVERSITY   (United States)

^d UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Embryonic stem cells; Gene expression; Self renewal

Indexed keywords

CYCLIN DEPENDENT KINASE 1; TRANSCRIPTION FACTOR CDX2;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; COLONY FORMATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE SILENCING; GENETIC ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA INTERFERENCE; SELF RENEWAL;

ANIMALS; APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; DOWN-REGULATION; EMBRYONIC STEM CELLS; GENETIC MARKERS; HOMEODOMAIN PROTEINS; LEUKEMIA INHIBITORY FACTOR; MICE; OCTAMER TRANSCRIPTION FACTOR-3; RNA INTERFERENCE; SOXB1 TRANSCRIPTION FACTORS; TRETINOIN;

EID: 79951797261     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23010     Document Type: Article

References (27)

1. Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R. 2003. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 17:126-140. (Pubitemid 36062514)
2. Becker KA, Ghule PN, Therrien JA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. 2006. Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. J Cell Physiol 209:883-893. (Pubitemid 44665710)
3. Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S, Smith A. 2003. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113:643-655. (Pubitemid 36694189)
4. Chen X, Xu H, Yuan P, Fang F, Huss M, Vega VB, Wong E, Orlov YL, Zhang W, Jiang J, Loh YH, Yeo HC, Yeo ZX, Narang V, Govindarajan KR, Leong B, Shahab A, Ruan Y, Bourque G, Sung WK, Clarke ND, Wei CL, Ng HH. 2008. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-1117. (Pubitemid 351787745)
5. Chew JL, Loh YH, Zhang W, Chen X, Tam WL, Yeap LS, Li P, Ang YS, Lim B, Robson P, Ng HH. 2005. Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 25:6031-6046. (Pubitemid 40946556)
6. Evans MJ, Kaufman MH. 1981. Establishment in culture of pluripotential cells from mouse embryos. Nature 292:154-156. (Pubitemid 11050741)
7. Faast R, White J, Cartwright P, Crocker L, Sarcevic B, Dalton S. 2004. Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a). Oncogene 23:491-502. (Pubitemid 38175004)
8. Fujikura J, Yamato E, Yonemura S, Hosoda K, Masui S, Nakao K, Miyazaki Ji J, Niwa H. 2002. Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev 16:784-789. (Pubitemid 34280102)
9. Hatano SY, Tada M, Kimura H, Yamaguchi S, Kono T, Nakano T, Suemori H, Nakatsuji N, Tada T. 2005. Pluripotential competence of cells associated with Nanog activity. Mech Dev 122:67-79. (Pubitemid 39593746)
10. Kyba M, Perlingeiro RC, Daley GQ. 2002. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 109:29-37. (Pubitemid 34327514)
11. Li M, Pevny L, Lovell-Badge R, Smith A. 1998. Generation of purified neural precursors from embryonic stem cells by lineage selection. Curr Biol 8:971-974. (Pubitemid 28447948)
12. Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, Chen X, Bourque G, George J, Leong B, Liu J, Wong KY, Sung KW, Lee CW, Zhao XD, Chiu KP, Lipovich L, Kuznetsov VA, Robson P, Stanton LW, Wei CL, Ruan Y, Lim B, Ng HH. 2006. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38:431-440.
13. Martin GR. 1981. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 78:7634-7638. (Pubitemid 12186197)
14. Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. 2003. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113:631-642. (Pubitemid 36694188)
15. Mittnacht S. 1998. Control of pRB phosphorylation. Curr Opin Genet Dev 8:21-27. (Pubitemid 28122136)
16. Morgan DO. 1997. Cyclin-dependent kinases: Engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 13:261-291. (Pubitemid 28034527)
17. Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I, Scholer H, Smith A. 1998. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95:379-391. (Pubitemid 28507326)
18. Niwa H, Miyazaki J, Smith AG. 2000. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 24:372-376. (Pubitemid 30187435)
19. Santamaria D, Barriere C, Cerqueira A, Hunt S, Tardy C, Newton K, Caceres JF, Dubus P, Malumbres M, Barbacid M. 2007. Cdk1 is sufficient to drive the mammalian cell cycle. Nature 448:811-815. (Pubitemid 47266342)
20. Satyanarayana A, Berthet C, Lopez-Molina J, Coppola V, Tessarollo L, Kaldis P. 2008. Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2. Development 135:3389-3400.
21. Savatier P, Lapillonne H, van Grunsven LA, Rudkin BB, Samarut J. 1996. Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene 12:309-322. (Pubitemid 26042568)
22. Stead E, White J, Faast R, Conn S, Goldstone S, Rathjen J, Dhingra U, Rathjen P, Walker D, Dalton S. 2002. Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities. Oncogene 21:8320-8333. (Pubitemid 35477872)
23. Trimarchi JM, Lees JA. 2002. Sibling rivalry in the E2F family. Nat Rev Mol Cell Biol 3:11-20. (Pubitemid 135709914)
24. Ullah Z, Kohn MJ, Yagi R, Vassilev LT, DePamphilis ML. 2008. Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity. Genes Dev 22:3024-3036.
25. Wang SH, Tsai MS, Chiang MF, Li H. 2003. A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells. Gene Expr Patterns 3:99-103. (Pubitemid 36358184)
26. Wang J, Rao S, Chu J, Shen X, Levasseur DN, Theunissen TW, Orkin SH. 2006. A protein interaction network for pluripotency of embryonic stem cells. Nature 444:364-368. (Pubitemid 44764111)
27. Zhang X, Neganova I, Przyborski S, Yang C, Cooke M, Atkinson SP, Anyfantis G, Fenyk S, Keith WN, Hoare SF, Hughes O, Strachan T, Stojkovic M, Hinds PW, Armstrong L, Lako M. 2009. A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. J Cell Biol 184:67-82.