DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  So, Ah Young ^a   Jung, Ji Won ^b   Lee, Seunghee ^a   Kim, Hyung Sik ^a   Kang, Kyung Sun ^a  

^a Seoul National University   (South Korea)

^b Korea National Institute of Health   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; BMI1 PROTEIN; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; HISTONE H3; LYSINE; MICRORNA; POLYCOMB GROUP PROTEIN; PROTEIN P16; PROTEIN P21; TRANSCRIPTION FACTOR EZH2; BMI1 PROTEIN, HUMAN; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DNA BINDING PROTEIN; ENZYME INHIBITOR; EZH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL AGING; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPIGENETICS; GENE EXPRESSION REGULATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MULTIPOTENT STEM CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; UMBILICAL CORD BLOOD; UPREGULATION; CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AZACITIDINE; BLOTTING, WESTERN; CELL AGING; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MICRORNAS; MULTIPOTENT STEM CELLS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

EID: 79955921676     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019503     Document Type: Article

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