Oxidative stress in liver diseases

International Journal of Pharmaceutical and Clinical Research

Volumn 5, Issue 4, 2013, Pages 155-164

  El Rigal, Nagy S ^a   Hamed, Manal A ^a   Rizk, Maha Z ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Alcoholism; Hepatocellular carcinoma; Liver; Oxidative stress

Indexed keywords

FREE RADICAL; PROTEASOME;

ALCOHOL METABOLISM; ALCOHOLISM; APOPTOSIS; CELL DEATH; CELL MEMBRANE; DISEASE ASSOCIATION; ENZYME DEGRADATION; GENE EXPRESSION; GENE MUTATION; GENOTYPE ENVIRONMENT INTERACTION; HOST RESISTANCE; HUMAN; LIPID PEROXIDATION; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER DISEASE; LIVER FIBROSIS; NONALCOHOLIC FATTY LIVER; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN METABOLISM; PROTEIN OXIDATION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; STRATUM CORNEUM;

EID: 84885231595     PISSN: None     EISSN: 09751556     Source Type: Journal    
DOI: None     Document Type: Review

References (114)

1. B. Halliwell, J.M.C. Gutteridge, Free Radicals in Biology and Medicine, third ed., Oxford University Press, Oxford (1999).
2. H. Sies, Oxidative stress. II. Oxidants and Antioxidants, Academic Press, London (1991).
3. O. Sorg, Oxidative stress: a theoretical model or a biological reality?, C. R. Biologies, 327 (2004) 649-662.
4. S.S. Liu, Generating, partitioning, targeting and functioning of superoxide in mitochondria, Biosci. Rep. 17 (3) (1997) 259-272.
5. S.C. Sahu, Dual role of organosulfur compounds in foods: a review, J. Environ. Sci. Health Part C Environ. Carcinog. Ecotoxicol. Rev. 20 (1) (2002) 61-76.
6. M. Chevion, T. Navok, G. Glaser, J. Mager, The chemistry of favism-inducing compounds. The properties of isouramil and divicine and their reaction with glutathione, Eur. J. Biochem. 127 (2) (1982) 405-409.
7. P. Boffetta, F. Nyberg, Contribution of environmental factors to cancer risk, Br. Med. Bull. 68 (1) (2003) 71-94.
8. Y.K. Youn, C. Lalonde, R. Demling, Oxidants and the pathophysiology of burn and smoke inhalation injury, Free Radic. Biol. Med. 12 (5) (1992) 409-415.
9. H.S. Black, Potential involvement of free radical reaction in ultraviolet light mediated cutaneous damage, Photochem. Photobiol. 46 (1987) 213-221.
10. L.L. Hruza, A.P. Pentland, Mechanisms of UVinduced inflammation, J. Invest. Dermatol. 100 (1) (1993) 3S-4S.
11. M. Ichihashi, M. Ueda, A. Budiyanto, T. Bito, M. Oka, M. Fukunaga, K. Tsuru, T. Horikawa, UVinduced skin damage, Toxicology 189 (1-2) (2003) 21-39.
12. S. Tahara, M. Matsuo, T. Kaneko, Age-related changes in oxidative damage to lipids and DNA in rat skin, Mech. Ageing Dev. 122 (4) (2001) 415-426.
13. M. Kuro-o, Disease model: human aging, Trends Mol. Med. 7 (4) (2001) 179-181.
14. D. Harman, Aging: overview, Ann. N.Y. Acad. Sci. 928 (2001) 1-21.
15. R.M. Tyrrell, Ultraviolet radiation and free radical damage to skin, Biochem. Soc. Symp. 61 (1995) 47-53.
16. J. Taira, K. Mimura, T. Yoneya, A. Hagi, A. Murakami, K. Makino, Hydroxyl radical formation by UV-irradiated epidermal cells, J. Biochem. (Tokyo) 111 (6) (1992) 693-695.
17. M.M. Mathews-Roth, Erythropoietic protoporphyria: treatment with antioxidants and potential cure with gene therapy, Methods Enzymol. 319 (2000) 479-484.
18. J.R. Kanofsky, Singlet oxygen production by biological systems, Chem. Biol. Interact. 70 (1-2) (1989) 1-28.
19. S. Raha, B.H. Robinson, Mitochondria, oxygen free radicals, disease and ageing, Trends Biochem. Sci. 25 (10) (2000) 502-508.
20. C.C. Winterbourn, Toxicity of iron and hydrogen peroxide: the Fenton reaction, Toxicol. Lett. 82-83 (1995) 969-974.
21. G.R. Buettner, B.A. Jurkiewicz, Catalytic metals, ascorbate and free radicals: combinations to avoid, Radiat. Res. 145 (1996) 532-541.
22. B.M. Babior, J.D. Lambeth, W. Nauseef, The neutrophil NADPH oxidase, Arch. Biochem. Biophys. 397 (2) (2002) 342-344.
23. A.W. Segal, A. Abo, The biochemical basis of the NADPH oxidase of phagocytes, Trends Biochem. Sci. 18 (1993) 43-47.
24. C.C. Winterbourn, M.C. Vissers, A.J. Kettle, Myeloperoxidase, Curr. Opin. Hematol. 7 (1) (2000) 53-58.
25. S.J. Klebanoff, Myeloperoxidase, Proc. Assoc. Am. Physicians 111 (5) (1999) 383-389.
26. T.M. Dawson, V.L. Dawson, Nitric oxide synthase: role as a transmitter/mediator in the brain and endocrine system, Ann. Rev. Med. 47 (1996) 219-227.
27. G.L. Squadrito, W.A. Pryor, The formation of peroxynitrite in vivo from nitric oxide and superoxide, Chem.-Biol. Interact. 96 (1995) 203-206.
28. W.A. Pryor, G.L. Squadrito, The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide, Am. J. Physiol. 268 (1995) L699-L722.
29. S. Toyokuni, Reactive oxygen species-induced molecular damage and its application in pathology, Pathol. Int. 49 (2) (1999) 91-102.
30. M. Amici, G. Lupidi, M. Angeletti, E. Fioretti, A.M. Eleuteri, Peroxynitrite-induced oxidation and its effects on isolated proteasomal systems, Free Radic. Biol. Med. 34 (8) (2003) 987-996.
31. R. Kohen, A. Nyska, Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification, Toxicol. Pathol. 30 (6) (2002) 620-650.
32. O. Blokhina, E. Virolainen, K.V. Fagerstedt, Antioxidants, oxidative damage and oxygen deprivation stress: a review, Ann. Bot. (Lond.) (special issue) 91 (2003) 179-194.
33. S.R. Pinnell, Cutaneous photodamage, oxidative stress, and topical antioxidant protection, J. Am. Acad. Dermatol. 48 (1) (2003) 1-19.
34. D.P. Steenvoorden, G.M. van Henegouwen, The use of endogenous antioxidants to improve photoprotection, J. Photochem. Photobiol. B 41 (1997) 1-10.
35. O. Sorg, C. Antille, J.-H. Saurat, Retinoids, other topical vitamins, and antioxidants, in: D.S. Rigel, R.S. Weiss, H.W. Lim, J.S. Dover (Eds.), Photoaging, Marcel Dekker, New York (2004) pp. 89-115.
36. J.J. Thiele, C. Schroeter, S.N. Hsieh, M. Podda, L. Packer, The antioxidant network of the stratum corneum, Curr. Probl. Dermatol. 29 (2001) 26-42.
37. Z.A. Wood, E. Schroder, J. Robin Harris, L.B. Poole, Structure, mechanism and regulation of peroxiredoxins, Trends Biochem. Sci. 28 (1) (2003) 32-40.
38. G.P. Biewenga, G.R. Haenen, A. Bast, The pharmacology of the antioxidant lipoic acid, Gen. Pharmacol. 29 (3) (1997) 315-331.
39. G. Chidlow, K.G. Schmidt, J.P. Wood, J. Melena, N.N. Osborne, alpha-lipoic acid protects the retina against ischemiareperfusion, Neuropharmacology 43 (6) (2002) 1015-1025.
40. M.A. Lynch, Lipoic acid confers protection against oxidative injury in non-neuronal and neuronal tissue, Nutr. Neurosci. 4 (6) (2001) 419-438.
41. S. Englard, S. Seifter, The biochemical functions of ascorbic acid, Annu. Rev. Nutr. 6 (1986) 365-406.
42. A.C. Chan, Partners in defense, vitamin E and vitamin C, Can.J. Physiol. Pharmacol. 71 (9) (1993) 725-731.
43. G.J. Handelman, The evolving role of carotenoids in human biochemistry, Nutrition 17 (10) (2001) 818-822.
44. F. Böhm, R. Edge, E.J. Land, D.J. McGarvey, T.G. Truscott, Carotenoids enhance vitamin E antioxidant efficiency, J. Am. Chem. Soc. 119 (1997) 621-622.
45. T. Iyama, A. Takasuga, M. Azuma, beta-Carotene accumulation in mouse tissues and a protective role against lipid peroxidation, Int. J. Vitam. Nutr. Res. 66 (1996) 301-305.
46. C.F. Rosen, Topical and systemic photoprotection, Dermatol. Ther. 16 (1) (2003) 8-15.
47. K. Pehr, R.R. Forsey, Why don't we use vitamin E in dermatology?, Can. Med. Assoc. J. 149 (9) (1993) 1247-1253.
48. M. Soffritti, F. Belpoggi, D.D. Esposti, L. Falcioni, L. Bua, Consequences of exposure to carcinogens beginning during developmental life, Basic Clin. Pharmacol. Toxicol. 102 (2008) 118-124.
49. H.Y. Chiou, S.T. Chiou, Y. H. Hsu, Y. L. Chou, C. H. Tseng, M. L. Wei, C. J. Chen, Incidence of transitional cell carcinoma and arsenic in drinking water: a follow-up study of 8,102 residents in an arseniasis-endemic area in northeastern Taiwan. Am. J. Epidemiol. 153 (2001) 411-418.
50. K. S. Kasprzak, Possible role of oxidative damage in metalinduced carcinogenesis. Cancer Invest. 13 (1995) 411-430.
51. E. Corsini, L. Asti, B. Viviani, M. Marinovich, C. L. Galli, Sodium arsenate induces overproduction of interleukin-1 alpha in murine keratinocytes: role of mitochondria. J. Invest. Dermatol. 113 (1999) 760-765.
52. H. Shi, L.G. Hudson, K.J. Liu, Oxidative stress and apoptosis in metal ion-induced carcinogenesis. Free Rad. Biol. Med. 37(5) (2004) 582-593.
53. M. Karin, JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action? Proc. Natl. Acad. Sci. 95 (1998) 9067-9069.
54. M. R. Young, J. J. Li, M. Rincon, F R. A. lavell, B. K. Sathyanarayana, R. Hunziker, N. Colburn, Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. Proc. Natl. Acad. Sci. 96 (1999) 9827-9832.
55. M. Marra, I.M. Sordelli2, A. Lombardi, M Lamberti, L. Tarantino, A. Giudice, K.L. El-Serag, Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview. J. Translational Med. 9 (2011) 171-184.
56. H.L. Ha, H.J. Shin, M.A. Feitelson, D.Y. Yu, Oxidative stress and antioxidants in hepatic pathogenesis, World J, Gastroenterol, 16(48) (2010) 6035-6043.
57. B. Nalpas, M. Feitelson, C. Bréchot, E. Rubin, Alcohol, hepatotropic viruses, and hepatocellular carcinoma. Alcohol Clin. Exp. Res. 19 (1995) 1089-1095.
58. B. Chen, M. Ning, G. Yang. Effect of Paeonol on Antioxidant and Immune Regulatory activity in hepatocellular carcinoma rats. Molecules, 17 (2012) 4672-4683.
59. G. Perry, A.K. Raina, A. Nunomura, T. Wataya, L.M. Sayre, M.A. Smith, How important is oxidative damage? Lessons from Alzheimer's disease. Free Radic. Biol. Med. 28 (2000) 831-834.
60. J. Choi, J.H. Ou, Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus. Am. J. Physiol. Gastrointest. Liver Physiol. 290 (2006) G847-G851.
61. J.L. Martindale, N.J. Holbrook, Cellular response to oxidative stress: signaling for suicide and survival. J. Cell Physiol, 192 (2002) 1-15.
62. M.T. Kuo, N. Savaraj, Roles of reactive oxygen species in hepatocarcinogenesis and drug resistance gene expression in liver cancers. Mol. Carcinog. 45 (2006) 701-709.
63. M.J. Czaja, Cell signaling in oxidative stressinduced liver injury. Semin Liver Dis. 27 (2007) 378-389.
64. S.T. Magness, R. Bataller, L. Yang, D.A. Brenner, A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations. Hepatology, 40 (2004) 1151-1159.
65. S. Ong, Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture. Biomaterials, 27 (2006) 4087-97.
66. S.L. Friedman, Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J. Biol. Chem. 275 (2000) 2247-2250.
67. N. Nieto, S.L. Friedman, P. Greenwel, A.I. Cederbaum, CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. Hepatology, 30 (1999) 987-96.
68. N. Nieto, S.L. Friedman, A.I. Cederbaum, Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species. Hepatology, 35 (2002), 62-73.
69. N. Nieto, P. Greenwel, S.L. Friedman, F. Zhang, A.J. Dannenberg, A.I. Cederbaum. Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. Role of H2O2 and cyclooxygenase-2. J. Biol. Chem. 275 (2000) 20136-45.
70. N. Nieto, S.L. Friedman, A.I. Cederbaum, Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells. J. Biol. Chem. 277 (2002) 9853-64.
71. F. Cubero, N. Nieto, Kupffer cells and alcoholic liver disease. Rev. Esp. Enferm. Dig. 98 (2006) 674-84.
72. H. Tsukamoto. Cytokine regulation of hepatic stellate cells in liver fibrosis. Alcohol Clin. Exp. Res. 23 (1999) 911-6.
73. W.R. Jarnagin, D.C. Rockey, V.E. Koteliansky, S.S. Wang, D.M. Bissell. Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J. Cell Biol. 127 (1994) 2037-48.
74. P. Giuseppe, Pathogenesis of liver fibrosis: role of oxidative stress. Mol. Asp. Med. 21 (2000) 49-98.
75. X. Zhou, A. Jamil, A. Nash, R.C. Benyon, Impaired proteolysis of collagen I inhibits proliferation of hepatic stellate cells: Implications for regulation of liver fibrosis. J. Biol. Chem. 281(2006) 39757-65.
76. Matrix degradation in liver: a role in injury and repair. Hepatology, 26 (1997) 1069-1071.
77. M.J. Arthur, Fibrosis and altered matrix degradation. Digestion, 59 (1998) 376-80.
78. M.J. Arthur, Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis. Am. J. Physiol Gastrointest. Liver Physiol. 279 (2000) G245-249.
79. K. Breitkopf, P. Godoy, L. Ciuclan, M.V. Singer, S. Dooley, TGFbeta/ Smad signaling in the injured liver. Z. Gastroenterol. 44 (2006) 57-66.
80. A.M. Gressner. Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J. Hepatol. 22 (1995) 28-36.
81. E.R. Garcia-Trevijano, M.J. Iraburu, L. Fontana, J.A Dominguez-Rosales, A. Auster, A. Covarrubias-Pinedo, Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells. Hepatology, 29 (1999) 960-970.
82. P. Greenwel, S. Tanaka, D. Penkov, W. Zhang, M. Olive, J. Moll, Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding proteins. Mol. Cell. Biol. 20 (2000) 912-918.
83. G. Svegliati-Baroni, Y. Inagaki, A.R. Rincón-Sánchez, Else C, Saccomanno S, Benedetti A, et al. Early response of alpha2(I) collagen to acetaldehyde in human hepatic stellate cells is TGFbeta independent. Hepatology, 42 (2005) 343-52.
84. G. Svegliati-Baroni, F. Ridolfi, A. Di Sario, S. Saccomanno, E. Bendia, A. Benedetti, Intracellular signaling pathways involved acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells. Hepatology, 33 (2001) 1130-40.
85. G. Poli. Pathogenesis of liver fibrosis: role of oxidative stress. Mol. Asp. Med. 21 (2000) 49-98.
86. H. Esterbauer, R.J. Schaur, H. Zollner. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11 (1991) 81-128.
87. R. Urtasun, Conde de la Rosa L, Nieto N. Oxidative and nitrosative stress and fibrogenic response. Clin. Liver Dis.12 (2008) 769-790.
88. H. Esterbauer, R.J. Schaur, H. Zollner, Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11 (1991) 81-128.
89. N. Nieto, Oxidative-Stress and IL-6 mediate the fibrogenic effects of rodent Kupffer cells on stellate cells. Hepatology, 44 (2006) 1487-501.
90. S. G. Baroni, L. D'Ambrosio, G. Ferretti, A. Casini, A. Di Sario, R. Salzano, Fibrogenic effect of oxidative stress on rat hepatic stellate cells. Hepatology, 27 (1998) 720-6.
91. N. Nieto, A.I. Cederbaum, Increased Sp1-dependent transactivation of the LAM gamma 1 promoter in hepatic stellate cells co-cultured with HepG2 cells overexpressing cytochrome P450 2E1. J. Biol. Chem. 278 (2003) 15360-15370.
92. S.K. Das, P. Nayak, D.M. Vasudevan, Consequences of ethanol consumption. J. Indian Soci. Toxicol. 1 (1) (2005) 1-10.
93. C.C. Cunningham, S.M. Bailey, Ethanol consumption and liver mitochondria function. Biological Signals and Receptors 10 (2001) 271-282.
94. C.S. Lieber, L.M. DeCarli, Hepatic microsomal ethanol-oxidizing system. In vitro characteristic and adaptive properties in vivo. J. Biol. Chem. 245 (1970) 2505-2512.
95. K.S. Salmela, I.G. Kessova, I.B. Tsyrolv, C.S. Lieber, Respective roles of cytochrome P450 2E1, 1A2, and 3A4 in the hepatic microsomal ethanol oxidizing system. Alcoholism Clin. Exper. Res. 22 (1998) 2125-2132.
96. G.D. Nordsblom, M.J. Coon, Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P450. Arch. Biochem. Biophys. 180 (1977) 343-347.
97. S.M. Klein, G. Cohen, C.S. Lieber, A.I. Cederbaum, Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol. Arch. Biochem. Biophy. 223 (1983) 425-432.
98. E. Rubin, D.S. Beattie, A. Toth, C.S. Lieber, Structural and functional effects of ethanol on hepatic mitochondria. Fed.n Proceedings 31 (1972) 131-140.
99. L.A. Videla, R. Rodrigo, J. Araya, J. Poniachik, Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease. Free Radic. Biol. Med. 37 (2004) 1499-1507.
100. LA. Videla, Oxidative stress and insulin resistance as interdependent pathogenic mechanisms in nonalcoholic fatty liver disease associated with obesity. In: Alvarez S, Evelson P, editors. Free Radical Pathophysiology. Kerala, India: Transworld Research Network (2008) 369-385.
101. A. Aronis, Z. Madar, O. Tirosh, Mechanism underlying oxidative stress-mediated lipotoxicity: exposure of J774.2 macrophages to triacylglycerols facilitates mitochondrial reactive oxygen species production and cellular necrosis. Free Radic. Biol. Med. 38 (2005) 1221-1230.
102. M. Comporti, J. Poniachik, LA. Videla, Effects of weight loss on liver and erythrocyte polyunsaturated fatty acid pattern and oxidative stress status in obese patients with nonalcoholic fatty liver disease. Biol. Res. 41 (2008) 59-68.
103. J.L. Evans, B.A. Maddux, I.D. Goldfine, The molecular basis for oxidative stress-induced insulin resistance. Antioxid. Redox. Signal 7 (2005) 1040-1052.
104. S.D. Clarke, The multi-dimensional regulation of gene expression by fatty acids: polyunsaturated fats as nutrient sensors. Curr. Opin. Lipidol. 15 (2004) 13-18.
105. F.C. Fang, Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity, J. Clin. Invest. 99 (12) (1997) 2818-2825.
106. J.P. Eiserich, S. Baldus, M.L. Brennan, W. Ma, C. Zhang, A. Tousson, L. Castro, A.J. Lusis, W.M. Nauseef, C.R. White, B.A. Freeman, Myeloperoxidase, a leukocyte-derived vascular NO oxidase, Science 296 (5577) (2002) 2391-2394.
107. W.L. Lee, R.E. Harrison, S. Grinstein, Phagocytosis by neutrophils, Microbes Infect. 5 (14) (2003) 1299-1306.
108. S.L. Hazen, F.F. Hsu, K. Duffin, J.W. Heinecke, Molecular chlorine generated by the myeloperoxidase hydrogen peroxide chloride system of phagocytes converts low-density lipoprotein cholesterol into a family of chlorinated sterols, J. Biol. Chem. 271 (1996) 23080-23088.
109. C.D. Funk, Prostaglandins and leukotrienes: advances in eicosanoid biology, Science 294 (2001) 1871-1875.
110. J. Lieb, Eicosanoids: the molecules of evolution, Med. Hypotheses 56 (6) (2001) 686-693.
111. E. de Lamirande, C. Gagnon, Impact of reactive oxygen species on spermatozoa: a balancing act between beneficial and detrimental effects, Hum. Reprod. (Suppl.) 10 (1) (1995) 15-21.
112. C. O'Flaherty, N. Beorlegui, M.T. Beconi, Participation of superoxide anion in the capacitation of cryopreserved bovine sperm, Int. J. Androl. 26 (2) (2003) 109-114.
113. A.F. Taub, Photodynamic therapy in dermatology: history and horizons, J. Drugs Dermatol. (Suppl.) 3 (1) (2004) S8-S25.
114. R. Bissonette, A. Bergeron, Y. Liu, Large-surface photodynamic therapy with aminolevulinic acid: treatment of actinic keratoses and beyond, J. Drugs Dermatol. (Suppl.) 3 (1) (2004) S26-S31.