Disease model: Human aging

Trends in Molecular Medicine

Volumn 7, Issue 4, 2001, Pages 179-181

  Kuro o, Makoto ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN KLOTHO; TELOMERASE; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; CONTROLLED STUDY; GENE DISRUPTION; GENE TARGETING; HUMAN; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PREMATURE AGING; REVIEW; SENESCENCE;

AGING; ANIMALS; BONE AND BONES; DISEASE MODELS, ANIMAL; GENOTYPE; GLUCURONIDASE; HUMANS; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; PHENOTYPE; TELOMERASE;

ANIMALIA; MAMMALIA;

EID: 0035061863     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(01)01921-9     Document Type: Review

References (10)

1. Mutation of the mouse klotho gene leads to a syndrome resembling ageing
2. Pathobiology of the senescence-accelerated mouse (SAM)
3. Positional cloning of the Werner's syndrome gene
4. Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 2
5. A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
6. Atm-deficient mice: A paradigm of ataxia telangiectasia
7. Longevity, stress response, an]d cancer in aging telomerase-deficient mice
8. Does growth hormone prevent or accelerate aging?
9. Mutation-causing mutations
10. Chromosomal damage rate, aging, and diet