Biomechanical force in blood development: Extrinsic physical cues drive pro-hematopoietic signaling

Differentiation

Volumn 86, Issue 3, 2013, Pages 92-103

  Lee, Hyun Jung ^a   Li, Nan ^a   Evans, Siobahn M ^a   Diaz, Miguel F ^a   Wenzel, Pamela L ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Biomechanical force; Cellular microenvironment; Hematopoietic stem cells; Hemogenic endothelium; Mechanotransduction; Shear stress

Indexed keywords

ADAM PROTEIN; CELL ADHESION MOLECULE; G PROTEIN COUPLED RECEPTOR; NITRIC OXIDE;

ARTICLE; BLOOD CELL; CELL FATE; CELL HOMING; CELL RENEWAL; CELL TYPE; ENDOTHELIUM; ENDOTHELIUM CELL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC SYSTEM; HUMAN; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOBLAST; PARACRINE SIGNALING; PERICYTE; PRIORITY JOURNAL; SECOND MESSENGER; SENSOR; SIGNAL TRANSDUCTION;

A DISINTEGRIN AND METALLOPROTEASE; ADAM; AGM; AORTA-GONAD-MESONEPHROS; BIOMECHANICAL FORCE; CALCIUM SENSING RECEPTOR; CASR; CELLULAR MICROENVIRONMENT; CHEMOKINE C-X-C MOTIF RECEPTOR; CXCR; DAG; DELTA-LIKE; DIACYLGLYCEROL; DLL; ECM; EXTRACELLULAR MATRIX; FA; FAK; FETAL LIVER KINASE-1; FLK-1; FOCAL ADHESION; FOCAL ADHESION KINASE; FRIZZLED; FZD; G PROTEIN-COUPLED RECEPTOR; GPCR; HEMATOPOIETIC STEM AND PROGENITOR CELLS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELLS; HEMOGENIC ENDOTHELIUM; HSC; HSPC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUVEC; ILK; INOSITOL TRIPHOSPHATE; INTEGRIN LINKED KINASE; IP3; MAPK; MECHANOTRANSDUCTION; MITOGEN ACTIVATED PROTEIN KINASE; NICD; NITRIC OXIDE SYNTHASE; NOS; NOTCH INTRACELLULAR DOMAIN; PGE2; PHOSPHATIDYLINOSITIDE 3-KINASE; PHOSPHOLIPASE C; PI3K; PKA; PKD; PLC; POLYCYSTIN; PROSTAGLANDIN E2; PROTEIN KINASE A; RHO-ASSOCIATED PROTEIN KINASE; ROCK; S1P; S1PR/EDG1; SDF1; SHEAR STRESS; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE 1-PHOSPHATE RECEPTOR; STROMAL DERIVED FACTOR 1; TRANSIENT RECEPTOR POTENTIAL VALLINOID TYPE 4; TRPV4;

ANIMALS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; STEM CELL NICHE; STRESS, MECHANICAL;

EID: 84884988277     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2013.06.004     Document Type: Article

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