메뉴 건너뛰기




Volumn 10, Issue 1, 2013, Pages

Metabolic effects of milk protein intake strongly depend on pre-existing metabolic and exercise status

Author keywords

Adipogenesis; Body weight; Branched chain amino acids; Glutaminolysis; Insulin resistance; microRNA; Milk proteins; mTORC1; Obesity; Prostate cancer

Indexed keywords

BRANCHED CHAIN AMINO ACID; GLUTAMIC ACID; GLUTAMINE; INSULIN; ISOLEUCINE; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MILK PROTEIN; MUSCLE PROTEIN; VALINE;

EID: 84884743285     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-10-60     Document Type: Review
Times cited : (13)

References (84)
  • 1
    • 84879829425 scopus 로고    scopus 로고
    • Milk protein for improved metabolic health: A review of the evidence
    • Milk protein for improved metabolic health: a review of the evidence. McGregor RA, Poppitt SD, Nutr Metab (Lond) 2013 10 1 46
    • (2013) Nutr Metab (Lond) , vol.10 , Issue.1 , pp. 46
    • McGregor, R.A.1    Poppitt, S.D.2
  • 2
    • 0014304603 scopus 로고
    • Influence of dietary deprivations on plasma concentrations of free amino acids of man
    • Influence of dietary deprivations on plasma concentrations of free amino acids of man. Adibi SA, J Appl Physiol 1968 25 52 57
    • (1968) J Appl Physiol , vol.25 , pp. 52-57
    • Adibi, S.A.1
  • 3
    • 0014669160 scopus 로고
    • Plasma amino acid levels and insulin secretion in obesity
    • Plasma amino acid levels and insulin secretion in obesity. Felig M, Cahill GF Jr, N Engl J Med 1969 281 811 816
    • (1969) N Engl J Med , vol.281 , pp. 811-816
    • Felig, M.1    Cahill Jr., G.F.2
  • 4
    • 63449111894 scopus 로고    scopus 로고
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, Lien LF, et al. Cell Metab 2009 9 311 326
    • (2009) Cell Metab , vol.9 , pp. 311-326
    • Newgard, C.B.1    An, J.2    Bain, J.R.3    Muehlbauer, M.J.4    Stevens, R.D.5    Lien, L.F.6
  • 5
    • 79959486598 scopus 로고    scopus 로고
    • Overstimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization: Lessons learnt from Laron syndrome
    • Overstimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization: lessons learnt from Laron syndrome. Melnik BC, John SM, Schmitz G, Nutr Metab (Lond) 2011 8 4
    • (2011) Nutr Metab (Lond) , vol.8 , pp. 4
    • Melnik, B.C.1    John, S.M.2    Schmitz, G.3
  • 6
    • 84866128888 scopus 로고    scopus 로고
    • Leucine signalling in the pathogenesis of type 2 diabetes and obesity
    • Leucine signalling in the pathogenesis of type 2 diabetes and obesity. Melnik BC, World J Diabetes 2012 3 3 38 53
    • (2012) World J Diabetes , vol.3 , Issue.3 , pp. 38-53
    • Melnik, B.C.1
  • 7
    • 84874800752 scopus 로고    scopus 로고
    • Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents
    • Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents. McCormack SE, Shaham O, McCarthy MA, Deik AA, Wang TJ, Gerszten RE, et al. Pediatr Obes 2013 8 1 52 61
    • (2013) Pediatr Obes , vol.8 , Issue.1 , pp. 52-61
    • McCormack, S.E.1    Shaham, O.2    McCarthy, M.A.3    Deik, A.A.4    Wang, T.J.5    Gerszten, R.E.6
  • 9
    • 84874792421 scopus 로고    scopus 로고
    • Insulin resistance and the metabolism of branched-chain amino acids
    • Insulin resistance and the metabolism of branched-chain amino acids. Lu J, Xie G, Jia W, Jia W, Front Med 2013 7 1 53 59
    • (2013) Front Med , vol.7 , Issue.1 , pp. 53-59
    • Lu, J.1    Xie, G.2    Jia, W.3    Jia, W.4
  • 10
    • 15544362097 scopus 로고    scopus 로고
    • High intakes of milk, but not meat, increase s-insulin and insulin resistance in 8-year-old boys
    • DOI 10.1038/sj.ejcn.1602086
    • High intakes of milk, but not meat, increase s-insulin and insulin resistance in 8-year-old boys. Hoppe C, Molgaard C, Vaag A, Barkholt V, Michaelsen KF, Eur J Clin Nutr 2005 59 3 393 398 (Pubitemid 40403293)
    • (2005) European Journal of Clinical Nutrition , vol.59 , Issue.3 , pp. 393-398
    • Hoppe, C.1    Molgaard, C.2    Vaag, A.3    Barkholt, V.4    Michaelsen, K.F.5
  • 11
    • 84878622190 scopus 로고    scopus 로고
    • Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
    • Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity. Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, et al. Am J Physiol Endocrinol Metab 2013 304 11 1175 E1187
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , Issue.11
    • Lackey, D.E.1    Lynch, C.J.2    Olson, K.C.3    Mostaedi, R.4    Ali, M.5    Smith, W.H.6
  • 12
    • 37149027613 scopus 로고    scopus 로고
    • Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
    • Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism. She P, Van Horn C, Reid T, Hutson SM, Cooney RN, Lynch CJ, Am J Physiol Endocrinol Metab 2007 293 1552 E1563
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • She, P.1    Van Horn, C.2    Reid, T.3    Hutson, S.M.4    Cooney, R.N.5    Lynch, C.J.6
  • 13
    • 70949093312 scopus 로고    scopus 로고
    • Metabolite profiling identifies candidate markers reflecting the clinical adaptations associated with Roux-en-Y gastric bypass surgery
    • Metabolite profiling identifies candidate markers reflecting the clinical adaptations associated with Roux-en-Y gastric bypass surgery. Mutch DM, Fuhrmann JC, Rein D, Wiemer JC, Bouillot JL, Poitou C, PLoS ONE 2009 4 11 7905
    • (2009) PLoS ONE , vol.4 , Issue.11 , pp. 57905
    • Mutch, D.M.1    Fuhrmann, J.C.2    Rein, D.3    Wiemer, J.C.4    Bouillot, J.L.5    Poitou, C.6
  • 14
    • 79955387227 scopus 로고    scopus 로고
    • Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese subjects despite identical weight loss
    • Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese subjects despite identical weight loss. Laferrere B, Reilly D, Arias S, Swerdlow N, Gorroochurn P, Bawa B, et al. Sci TranlMed 2011 3 80 82
    • (2011) Sci TranlMed , vol.3 , pp. 80-82
    • Laferrere, B.1    Reilly, D.2    Arias, S.3    Swerdlow, N.4    Gorroochurn, P.5    Bawa, B.6
  • 15
    • 0032567822 scopus 로고    scopus 로고
    • Slow and fast dietary proteins
    • DOI 10.1038/35993
    • Slow and fast dietary proteins. Frühbeck G, Nature 1998 391 843 845 (Pubitemid 28157647)
    • (1998) Nature , vol.391 , Issue.6670 , pp. 843-845
    • Fruhbeck, G.1
  • 17
    • 0021965878 scopus 로고
    • Paleolithic nutrition. A consideration of its nature and current implications
    • Paleolithic nutrition. A consideration of its nature and current implications. Eaton SB, Konner M, N Engl J Med 1985 313 283 289 (Pubitemid 15199367)
    • (1985) New England Journal of Medicine , vol.312 , Issue.5 , pp. 283-289
    • Eaton, S.B.1    Konner, M.2
  • 19
    • 84856724533 scopus 로고    scopus 로고
    • Paleolithic diets as model for prevention and treatment of Western disease
    • Paleolithic diets as model for prevention and treatment of Western disease. Lindeberg S, Am J Hum Biol 2012 24 110 115
    • (2012) Am J Hum Biol , vol.24 , pp. 110-115
    • Lindeberg, S.1
  • 20
    • 79955013712 scopus 로고    scopus 로고
    • Regulation of protein synthesis by amino acids in muscle of neonates
    • Regulation of protein synthesis by amino acids in muscle of neonates. Suryawan A, Davis TA, Front Biosci 2012 16 1445 1460
    • (2012) Front Biosci , vol.16 , pp. 1445-1460
    • Suryawan, A.1    Davis, T.A.2
  • 21
    • 84878781295 scopus 로고    scopus 로고
    • Differential dose response of mTOR signaling to oral administration of leucine in skeletal muscle and liver in rats
    • Differential dose response of mTOR signaling to oral administration of leucine in skeletal muscle and liver in rats. Yoshizawa F, Mochizuki S, Sugahara K, Biosci Biotech Biochem 2013 77 4 839 842
    • (2013) Biosci Biotech Biochem , vol.77 , Issue.4 , pp. 839-842
    • Yoshizawa, F.1    Mochizuki, S.2    Sugahara, K.3
  • 22
    • 33746622168 scopus 로고    scopus 로고
    • Regulation of mTOR by mechanically induced signaling events in skeletal muscle
    • Regulation of mTOR by mechanically induced signaling events in skeletal muscle. Hornberger TA, Sukhija KB, Chien S, Cell Cycle 2006 5 13 1391 1396 (Pubitemid 44153645)
    • (2006) Cell Cycle , vol.5 , Issue.13 , pp. 1391-1396
    • Hornberger, T.A.1    Sukhija, K.B.2    Chien, S.3
  • 23
    • 79960925868 scopus 로고    scopus 로고
    • Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle
    • Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle. Hornberger TA, Int J Biochem Cell Biol 2011 43 1267 1276
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 1267-1276
    • Hornberger, T.A.1
  • 24
    • 84884254389 scopus 로고    scopus 로고
    • Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome
    • Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome. Jacobs BL, You JS, Frey JW, Goodman CA, Gundermann DM, Hornberger TA, J Physiol 2013 591 4611 4620
    • (2013) J Physiol , vol.591 , pp. 4611-4620
    • Jacobs, B.L.1    You, J.S.2    Frey, J.W.3    Goodman, C.A.4    Gundermann, D.M.5    Hornberger, T.A.6
  • 26
    • 84894486696 scopus 로고    scopus 로고
    • Nutrient regulation of the mTOR complex 1 signaling pathway
    • Nutrient regulation of the mTOR complex 1 signaling pathway. Kim SG, Buel GR, Blenis J, Mol Cells 2013 35 463 473
    • (2013) Mol Cells , vol.35 , pp. 463-473
    • Kim, S.G.1    Buel, G.R.2    Blenis, J.3
  • 27
    • 43549114054 scopus 로고    scopus 로고
    • Protein quality assessment: Impact of expanding understanding of protein and amino acid needs for optimal health
    • Protein quality assessment: impact of expanding understanding of protein and amino acid needs for optimal health. Millward DJ, Layman DK, Tomé D, Schaafsma G, Am J Clin Nutr 2008 87 1576S 1581S (Pubitemid 351679814)
    • (2008) American Journal of Clinical Nutrition , vol.87 , Issue.5
    • Millward, D.J.1    Layman, D.K.2    Tome, D.3    Schaafsma, G.4
  • 28
    • 0037321280 scopus 로고    scopus 로고
    • Casein and whey exert different effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite
    • DOI 10.1079/BJN2002760
    • Casein and whey exert different effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite. Hall WL, Millward DJ, Long SJ, Morgan LM, Br J Nutr 2003 89 2 239 248 (Pubitemid 36215862)
    • (2003) British Journal of Nutrition , vol.89 , Issue.2 , pp. 239-248
    • Hall, W.L.1    Millward, D.J.2    Long, S.J.3    Morgan, L.M.4
  • 30
    • 79952017041 scopus 로고    scopus 로고
    • Whey protein ingestion activates mTOR-dependent signalling after resistance exercise in young men: A double-blinded randomized controlled trial
    • Whey protein ingestion activates mTOR-dependent signalling after resistance exercise in young men: a double-blinded randomized controlled trial. Farnfield MM, Carey KA, Gran P, Trenerry MK, Cameron-Smith D, Nutrients 2009 1 263 275
    • (2009) Nutrients , vol.1 , pp. 263-275
    • Farnfield, M.M.1    Carey, K.A.2    Gran, P.3    Trenerry, M.K.4    Cameron-Smith, D.5
  • 31
    • 80052591726 scopus 로고    scopus 로고
    • Increased consumption of dairy foods and protein during diet- and exercise- induced weight loss promotes fat mass loss and lean mass in overweight and obese premenopausal women
    • Increased consumption of dairy foods and protein during diet- and exercise- induced weight loss promotes fat mass loss and lean mass in overweight and obese premenopausal women. Josse AR, Atkinson SA, Tarnopolsky MA, Phillips SM, J Nutr 2011 141 1626 1634
    • (2011) J Nutr , vol.141 , pp. 1626-1634
    • Josse, A.R.1    Atkinson, S.A.2    Tarnopolsky, M.A.3    Phillips, S.M.4
  • 32
    • 34147133191 scopus 로고    scopus 로고
    • Metabolic effects of amino acid mixtures and whey protein in healthy subjects: Studies using glucose-equivalent drinks
    • Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks. Nilsson M, Holst JJ, Björck IE, Am J Clin Nutr 2007 85 996 1004 (Pubitemid 46557914)
    • (2007) American Journal of Clinical Nutrition , vol.85 , Issue.4 , pp. 996-1004
    • Nilsson, M.1    Holst, J.J.2    Bjorck, I.M.E.3
  • 33
    • 36949089792 scopus 로고
    • Elevated serum insulin associated with leucine-induced hypoglycaemia
    • Elevated serum insulin associated with leucine-induced hypoglycaemia. DiGeorge AM, Auerbach VH, Mabry CC, Nature 1960 188 1036 1037
    • (1960) Nature , vol.188 , pp. 1036-1037
    • Digeorge, A.M.1    Auerbach, V.H.2    Mabry, C.C.3
  • 34
    • 0014972021 scopus 로고
    • Hypersecretion of insulin after the administration of L-leucine to obese children
    • Hypersecretion of insulin after the administration of L-leucine to obese children. Loridan L, Sadeghi-Nejad A, Senior B, J Pediatr 1971 78 53 58
    • (1971) J Pediatr , vol.78 , pp. 53-58
    • Loridan, L.1    Sadeghi-Nejad, A.2    Senior, B.3
  • 35
    • 55649124531 scopus 로고    scopus 로고
    • Leucine, when ingested with glucose, synergistically stimulates insulin secretion and lowers blood glucose
    • Leucine, when ingested with glucose, synergistically stimulates insulin secretion and lowers blood glucose. Kalogeropoulou D, LaFave L, Schweim K, Gannon MC, Nuttall FQ, Metabolism 2008 57 1747 1752
    • (2008) Metabolism , vol.57 , pp. 1747-1752
    • Kalogeropoulou, D.1    Lafave, L.2    Schweim, K.3    Gannon, M.C.4    Nuttall, F.Q.5
  • 37
    • 84872162703 scopus 로고    scopus 로고
    • Skim milk, whey, and casein increase body weight and whey and casein increase the plasma C-peptide concentration in overweight adolescents
    • Skim milk, whey, and casein increase body weight and whey and casein increase the plasma C-peptide concentration in overweight adolescents. Arnberg K, Mølgaard C, Michaelsen KF, Jensen SM, Trolle E, Larnkjær A, J Nutr 2012 142 2083 2090
    • (2012) J Nutr , vol.142 , pp. 2083-2090
    • Arnberg, K.1    Mølgaard, C.2    Michaelsen, K.F.3    Jensen, S.M.4    Trolle, E.5    Larnkjær, A.6
  • 39
    • 84856716614 scopus 로고    scopus 로고
    • Cow milk consumption, insulin-like growth factor-I, and human biology: A life history approach
    • Cow milk consumption, insulin-like growth factor-I, and human biology: a life history approach. Wiley AS, Am J Hum Biol 2012 24 130 138
    • (2012) Am J Hum Biol , vol.24 , pp. 130-138
    • Wiley, A.S.1
  • 40
    • 77953555973 scopus 로고    scopus 로고
    • Dairy and milk consumption and child growth: Is BMI involved? An analysis of NHANES 1999-2004
    • Dairy and milk consumption and child growth: is BMI involved? An analysis of NHANES 1999-2004. Wiley AS, Am J Hum Biol 2010 22 517 525
    • (2010) Am J Hum Biol , vol.22 , pp. 517-525
    • Wiley, A.S.1
  • 42
    • 0034222276 scopus 로고    scopus 로고
    • Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults
    • Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults. Barr SI, McCarron DA, Heany RP, Dawson-Highes B, Berga SL, Stern JS, et al. J Am Diet Assoc 2000 100 810 817
    • (2000) J Am Diet Assoc , vol.100 , pp. 810-817
    • Barr, S.I.1    McCarron, D.A.2    Heany, R.P.3    Dawson-Highes, B.4    Berga, S.L.5    Stern, J.S.6
  • 43
    • 84878940048 scopus 로고    scopus 로고
    • Chronic leucine supplementation increases body weight and insulin sensitivity in rats on high-fat diet likely by promoting insulin signalling in insulin-target tissues
    • Chronic leucine supplementation increases body weight and insulin sensitivity in rats on high-fat diet likely by promoting insulin signalling in insulin-target tissues. Li X, Wang X, Liu R, Ma Y, Guo H, Hao L, et al. Mol Nutr Food Res 2013 57 6 1067 1079
    • (2013) Mol Nutr Food Res , vol.57 , Issue.6 , pp. 1067-1079
    • Li, X.1    Wang, X.2    Liu, R.3    Ma, Y.4    Guo, H.5    Hao, L.6
  • 45
    • 77952007543 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
    • Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony. Foster KG, Fingar DC, J Biol Chem 2010 285 19 14071 14077
    • (2010) J Biol Chem , vol.285 , Issue.19 , pp. 14071-14077
    • Foster, K.G.1    Fingar, D.C.2
  • 46
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • mTOR: from growth signal integration to cancer, diabetes and ageing. Zoncu R, Efeyan A, Sabatini DM, Nat Rev Mol Cell Biol 2011 12 21 35
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 47
    • 0031730304 scopus 로고    scopus 로고
    • Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes
    • Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes. Fox HL, Pham PT, Kimball SR, Jefferson LS, Lynch CJ, Am J Physiol 1998 275 1232 C1238
    • (1998) Am J Physiol , vol.275
    • Fox, H.L.1    Pham, P.T.2    Kimball, S.R.3    Jefferson, L.S.4    Lynch, C.J.5
  • 48
    • 0034618364 scopus 로고    scopus 로고
    • Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes
    • Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes. Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS Jr, Lynch CJ, J Cell Biochem 2000 79 427 441
    • (2000) J Cell Biochem , vol.79 , pp. 427-441
    • Pham, P.T.1    Heydrick, S.J.2    Fox, H.L.3    Kimball, S.R.4    Jefferson Jr., L.S.5    Lynch, C.J.6
  • 49
    • 84862777407 scopus 로고    scopus 로고
    • Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway
    • Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway. Han JM, Jeong SJ, Park MC, Kim G, Kwon NH, Kim HK, et al. Cell 2012 149 410 424
    • (2012) Cell , vol.149 , pp. 410-424
    • Han, J.M.1    Jeong, S.J.2    Park, M.C.3    Kim, G.4    Kwon, N.H.5    Kim, H.K.6
  • 50
    • 84880906852 scopus 로고    scopus 로고
    • Mechanistic target of rapamycin (mTOR) controls homeostasis of adipogenesis
    • Mechanistic target of rapamycin (mTOR) controls homeostasis of adipogenesis. Yoon MS, Zhang C, Sun Y, Schoenherr CJ, Chen J, J Lipid Res 2013 54 8 2166 2173
    • (2013) J Lipid Res , vol.54 , Issue.8 , pp. 2166-2173
    • Yoon, M.S.1    Zhang, C.2    Sun, Y.3    Schoenherr, C.J.4    Chen, J.5
  • 51
    • 79952025848 scopus 로고    scopus 로고
    • Milk intake and total dairy consumption: Associations with early menarche in NHANES 1999-2004
    • Milk intake and total dairy consumption: associations with early menarche in NHANES 1999-2004. Wiley AS, PLoS ONE 2011 6 14685
    • (2011) PLoS ONE , vol.6 , pp. 514685
    • Wiley, A.S.1
  • 52
    • 79956313504 scopus 로고    scopus 로고
    • Age at menarche and metabolic markers for type 2 diabetes in premenopausal women: The BioCycle Study
    • Age at menarche and metabolic markers for type 2 diabetes in premenopausal women: the BioCycle Study. Chen L, Zhang C, Yeung E, Ye A, Mumford SL, Wactawski-Wende J, et al. J Clin Endocrinol Metab 2011 96 1007 E1012
    • (2011) J Clin Endocrinol Metab , vol.96
    • Chen, L.1    Zhang, C.2    Yeung, E.3    Ye, A.4    Mumford, S.L.5    Wactawski-Wende, J.6
  • 53
    • 84858656679 scopus 로고    scopus 로고
    • The role of BMI across the life course in the relationship between age at menarche and diabetes, in a British Birth Cohort
    • The role of BMI across the life course in the relationship between age at menarche and diabetes, in a British Birth Cohort. Pierce MB, Kuh D, Hardy R, Diabet Med 2012 29 600 603
    • (2012) Diabet Med , vol.29 , pp. 600-603
    • Pierce, M.B.1    Kuh, D.2    Hardy, R.3
  • 54
    • 84863376235 scopus 로고    scopus 로고
    • Age at menarche, the leg length to sitting height ratio, and risk of diabetes in middle-aged and elderly Chinese men and women
    • Age at menarche, the leg length to sitting height ratio, and risk of diabetes in middle-aged and elderly Chinese men and women. Conway BN, Shu XO, Zhang X, Xiang YB, Cai H, Li H, et al. PLoS ONE 2012 7 30625
    • (2012) PLoS ONE , vol.7 , pp. 530625
    • Conway, B.N.1    Shu, X.O.2    Zhang, X.3    Xiang, Y.B.4    Cai, H.5    Li, H.6
  • 55
    • 84866070536 scopus 로고    scopus 로고
    • Age at menarche and risk of type 2 diabetes among African-American and white women in the Atherosclerosis Risk in Communities (ARIC) study
    • Age at menarche and risk of type 2 diabetes among African-American and white women in the Atherosclerosis Risk in Communities (ARIC) study. Dreyfus JG, Lutsey PL, Huxley R, Pankow JS, Selvin E, Fernández-Rhodes L, et al. Diabetologia 2012 55 2371 2380
    • (2012) Diabetologia , vol.55 , pp. 2371-2380
    • Dreyfus, J.G.1    Lutsey, P.L.2    Huxley, R.3    Pankow, J.S.4    Selvin, E.5    Fernández-Rhodes, L.6
  • 56
    • 84857427697 scopus 로고    scopus 로고
    • Age at menarche and its association with the metabolic syndrome and its components: Results from the KORA F4 study
    • Age at menarche and its association with the metabolic syndrome and its components: results from the KORA F4 study. Stöckl D, Meisinger C, Peters A, Thorand B, Huth C, Heier M, et al. PLoS ONE 2011 6 26076
    • (2011) PLoS ONE , vol.6 , pp. 526076
    • Stöckl, D.1    Meisinger, C.2    Peters, A.3    Thorand, B.4    Huth, C.5    Heier, M.6
  • 57
    • 33646549283 scopus 로고    scopus 로고
    • Nutritional evaluation of casein and whey proteins and their hydrolysates from Protamex
    • Nutritional evaluation of casein and whey proteins and their hydrolysates from Protamex. Sindayikengera S, Xia WS, J Zhejiang Univ SCIENCE B 2006 7 2 90 98
    • (2006) J Zhejiang Univ SCIENCE B , vol.7 , Issue.2 , pp. 90-98
    • Sindayikengera, S.1    Xia, W.S.2
  • 58
    • 1542374749 scopus 로고    scopus 로고
    • Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets
    • DOI 10.1007/s00125-003-1306-2
    • Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets. Carobbio S, Ishihara H, Fernandez-Pascual S, Bartley C, Martin-Del-Rio R, Maechler P, Diabetologica 2004 47 266 276 (Pubitemid 38315363)
    • (2004) Diabetologia , vol.47 , Issue.2 , pp. 266-276
    • Carobbio, S.1    Ishihara, H.2    Fernandez-Pascual, S.3    Bartley, C.4    Martin-Del-Rio, R.5    Maechler, P.6
  • 59
    • 0000941835 scopus 로고
    • An effect of L-leucine and other essential amino acids on the structure and activity of glutamic dehydrogenase
    • An effect of L-leucine and other essential amino acids on the structure and activity of glutamic dehydrogenase. Yielding KL, Tomkins GM, Proc Natl Acad Sci USA 1961 47 983 989
    • (1961) Proc Natl Acad Sci USA , vol.47 , pp. 983-989
    • Yielding, K.L.1    Tomkins, G.M.2
  • 60
    • 84857804808 scopus 로고    scopus 로고
    • The structure and allosteric regulation of mammalian glutamate dehydrogenase
    • The structure and allosteric regulation of mammalian glutamate dehydrogenase. Li M, Li C, Allen A, Stanley CA, Smith TJ, Arch Biochem Biophys 2012 519 2 69 80
    • (2012) Arch Biochem Biophys , vol.519 , Issue.2 , pp. 69-80
    • Li, M.1    Li, C.2    Allen, A.3    Stanley, C.A.4    Smith, T.J.5
  • 61
    • 0032528917 scopus 로고    scopus 로고
    • Amino acid availability regulates p70 S6 kinase and multiple translation factors
    • Amino acid availability regulates p70 S6 kinase and multiple translation factors. Wang X, Campbell LE, Miller CM, Proud CG, Biochem J 1998 334 261 267 (Pubitemid 28420997)
    • (1998) Biochemical Journal , vol.334 , Issue.1 , pp. 261-267
    • Wang, X.1    Campbell, L.E.2    Miller, C.M.3    Proud, C.G.4
  • 66
    • 4544343980 scopus 로고    scopus 로고
    • Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
    • DOI 10.1016/j.cub.2004.08.026, PII S0960982204006116
    • Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Shah OJ, Wang Z, Hunter T, Curr Biol 2004 14 1650 1656 (Pubitemid 39239362)
    • (2004) Current Biology , vol.14 , Issue.18 , pp. 1650-1656
    • Shah, O.J.1    Wang, Z.2    Hunter, T.3
  • 67
    • 84880912548 scopus 로고    scopus 로고
    • Milk is not just food but most likely a genetic transfection system activating mTORC1 signalling for postnatal growth
    • Milk is not just food but most likely a genetic transfection system activating mTORC1 signalling for postnatal growth. Melnik BC, John SM, Schmitz G, Nutr J 2013 12 103
    • (2013) Nutr J , vol.12 , pp. 103
    • Melnik, B.C.1    John, S.M.2    Schmitz, G.3
  • 68
    • 84857675728 scopus 로고    scopus 로고
    • The mTOR signalling pathway in human cancer
    • The mTOR signalling pathway in human cancer. Pópulo H, Lopes JM, Soares P, Int J Mol Sci 2012 13 1886 1918
    • (2012) Int J Mol Sci , vol.13 , pp. 1886-1918
    • Pópulo, H.1    Lopes, J.M.2    Soares, P.3
  • 69
    • 84862777192 scopus 로고    scopus 로고
    • The translational landscape of mTOR signaling steers cancer initiation and metastasis
    • The translational landscape of mTOR signaling steers cancer initiation and metastasis. Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, et al. Nature 2012 485 7396 55 61
    • (2012) Nature , vol.485 , Issue.7396 , pp. 55-61
    • Hsieh, A.C.1    Liu, Y.2    Edlind, M.P.3    Ingolia, N.T.4    Janes, M.R.5    Sher, A.6
  • 70
    • 84864914359 scopus 로고    scopus 로고
    • The impact of cow's milk-mediated mTORC1-signalling in the initiation and progression of prostate cancer
    • The impact of cow's milk-mediated mTORC1-signalling in the initiation and progression of prostate cancer. Melnik BC, John SM, Carrera-Bastos P, Cordain L, Nutr Metab (Lond) 2012 9 1 74
    • (2012) Nutr Metab (Lond) , vol.9 , Issue.1 , pp. 74
    • Melnik, B.C.1    John, S.M.2    Carrera-Bastos, P.3    Cordain, L.4
  • 72
    • 84873054570 scopus 로고    scopus 로고
    • Whole milk intake is associated with prostate cancer-specific mortality among U.S. Male physicians
    • Whole milk intake is associated with prostate cancer-specific mortality among U.S. male physicians. Song Y, Chavarro JE, Cao Y, Qiu W, Mucci L, Sesso HD, et al. J Nutr 2013 143 2 189 196
    • (2013) J Nutr , vol.143 , Issue.2 , pp. 189-196
    • Song, Y.1    Chavarro, J.E.2    Cao, Y.3    Qiu, W.4    Mucci, L.5    Sesso, H.D.6
  • 73
    • 77957567010 scopus 로고    scopus 로고
    • Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products
    • Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Chen X, Gao C, Li H, Huang L, Sun Q, Dong Y, et al. Cell Res 2010 20 1128 1137
    • (2010) Cell Res , vol.20 , pp. 1128-1137
    • Chen, X.1    Gao, C.2    Li, H.3    Huang, L.4    Sun, Q.5    Dong, Y.6
  • 74
    • 84865339380 scopus 로고    scopus 로고
    • Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions
    • Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions. Izumi H, Kosaka N, Shimizu T, Sekine K, Ochiya T, Takase M, J Dairy Sci 2012 95 4831 4841
    • (2012) J Dairy Sci , vol.95 , pp. 4831-4841
    • Izumi, H.1    Kosaka, N.2    Shimizu, T.3    Sekine, K.4    Ochiya, T.5    Takase, M.6
  • 76
    • 79959315095 scopus 로고    scopus 로고
    • Apoptosis and the target genes of miR-21
    • Apoptosis and the target genes of miR-21. Becker Buscaglia LE, Li Y, Chin J Cancer 2011 30 371 380
    • (2011) Chin J Cancer , vol.30 , pp. 371-380
    • Becker Buscaglia, L.E.1    Li, Y.2
  • 77
    • 73349117464 scopus 로고    scopus 로고
    • Mir-21 regulates adipogenic differentiation through the modulation of TGF-β signalling in mesenchymal stem cells derived from human adipose tissue
    • Mir-21 regulates adipogenic differentiation through the modulation of TGF-β signalling in mesenchymal stem cells derived from human adipose tissue. Kim YJ, Hwang SJ, Bae YC, Jung JS, Stem Cells 2009 27 3093 3102
    • (2009) Stem Cells , vol.27 , pp. 3093-3102
    • Kim, Y.J.1    Hwang, S.J.2    Bae, Y.C.3    Jung, J.S.4
  • 78
    • 84857338212 scopus 로고    scopus 로고
    • Milk stimulates growth of prostate cancer cells in culture
    • Milk stimulates growth of prostate cancer cells in culture. Tate PL, Bibb R, Larcom LL, Nutr Cancer 2011 63 8 1361 1366
    • (2011) Nutr Cancer , vol.63 , Issue.8 , pp. 1361-1366
    • Tate, P.L.1    Bibb, R.2    Larcom, L.L.3
  • 80
    • 84855518254 scopus 로고    scopus 로고
    • Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs
    • Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs. Frost RJ, Olson EN, Proc Natl Acad Sci U S A 2011 52 21075 21080
    • (2011) Proc Natl Acad Sci U S A , vol.52 , pp. 21075-21080
    • Frost, R.J.1    Olson, E.N.2
  • 81
    • 72949117234 scopus 로고    scopus 로고
    • Amino acid imbalance explains extension of lifespan by dietary restriction in Drosophila
    • Amino acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Grandison RC, Piper MDW, Partridge L, Nature 2009 462 7276 1061 1064
    • (2009) Nature , vol.462 , Issue.7276 , pp. 1061-1064
    • Grandison, R.C.1    Piper, M.D.W.2    Partridge, L.3
  • 82
    • 79954628465 scopus 로고    scopus 로고
    • The plate half-full: Status of research on the mechanisms of dietary restriction in Drosophila melanogaster
    • The plate half-full: Status of research on the mechanisms of dietary restriction in Drosophila melanogaster. Tartar M, Exp Gerontol 2011 46 5 363 368
    • (2011) Exp Gerontol , vol.46 , Issue.5 , pp. 363-368
    • Tartar, M.1
  • 83
    • 84870885054 scopus 로고    scopus 로고
    • Amino acid sensing in dietary-restriction-mediated longevity: Roles of signal-transducing kinases GCN2 and TOR
    • Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR. Gallinetti J, Harputlugil E, Mitchell JR, Biochem J 2013 449 1 1 10
    • (2013) Biochem J , vol.449 , Issue.1 , pp. 1-10
    • Gallinetti, J.1    Harputlugil, E.2    Mitchell, J.R.3
  • 84
    • 77955747346 scopus 로고    scopus 로고
    • With TOR less is more. A key role for the conserved nutrient sensing TOR pathway in aging
    • With TOR less is more. A key role for the conserved nutrient sensing TOR pathway in aging. Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, Thomas EL, et al. Cell Metab 2010 11 6 453 465
    • (2010) Cell Metab , vol.11 , Issue.6 , pp. 453-465
    • Kapahi, P.1    Chen, D.2    Rogers, A.N.3    Katewa, S.D.4    Li, P.W.5    Thomas, E.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.