Chronic leucine supplementation increases body weight and insulin sensitivity in rats on high-fat diet likely by promoting insulin signaling in insulin-target tissues

Molecular Nutrition and Food Research

Volumn 57, Issue 6, 2013, Pages 1067-1079

  Li, Xiang ^a   Wang, Xiaolei ^a   Liu, Rui ^a,c   Ma, Yan ^a   Guo, Huailan ^c   Hao, Liping ^a   Yao, Ping ^a   Liu, Liegang ^a   Sun, Xiufa ^a   He, Ka ^b   Cao, Wenhong ^b   Yang, Xuefeng ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b University of North Carolina   (United States)

^c HUBEI UNIVERSITY OF MEDICINE   (China)

Author keywords

Gluconeogenesis; Insulin resistance; Insulin signaling; Leucine; Obesity

Indexed keywords

CYTOKINE; INSULIN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; LEUCINE; MTOR PROTEIN, RAT; TARGET OF RAPAMYCIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE;

ADIPOSE TISSUE; ANIMAL; ARTICLE; BLOOD; BODY WEIGHT; CALORIC INTAKE; DIET SUPPLEMENTATION; DRUG EFFECT; GENETICS; GLUCONEOGENESIS; INSULIN RESISTANCE; LIPID DIET; LIVER; MALE; METABOLISM; OXIDATIVE STRESS; PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT;

ADIPOSE TISSUE; ANIMALS; BODY WEIGHT; CYTOKINES; DIET, HIGH-FAT; DIETARY SUPPLEMENTS; ENERGY INTAKE; GLUCONEOGENESIS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LEUCINE; LIVER; MALE; MUSCLE, SKELETAL; OXIDATIVE STRESS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

MAMMALIA; RATTUS;

EID: 84878940048     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200311     Document Type: Article

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