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Volumn 304, Issue 11, 2013, Pages

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

(19)  Lackey, Denise E a   Lynch, Christopher J b   Olson, Kristine C b   Mostaedi, Rouzbeh c   Ali, Mohamed c   Smith, William H c   Karpe, Fredrik d   Humphreys, Sandy d   Bedinger, Daniel H e,f   Dunn, Tamara N e   Thomas, Anthony P e   Oort, Pieter J a   Kieffer, Dorothy A e   Amin, Rajesh g   Bettaieb, Ahmed e   Haj, Fawaz G e   Permana, Paska h   Anthony, Tracy G i   Adams, Sean H a,e  


Author keywords

Bariatric; Diabetes; Hyperinsulinemia; Mammalian target of rapamycin; Protein

Indexed keywords

2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; 2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); BRANCHED CHAIN AMINO ACID; DEOXYGLUCOSE; INSULIN; MESSENGER RNA; N (2 BENZOYLPHENYL) O [2 (METHYL 2 PYRIDINYLAMINO)ETHYL]TYROSINE;

EID: 84878622190     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00630.2012     Document Type: Article
Times cited : (253)

References (52)
  • 1
    • 84862282554 scopus 로고    scopus 로고
    • Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state
    • Adams SH. Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state. Adv Nutr 2: 445-456, 2011.
    • (2011) Adv Nutr , vol.2 , pp. 445-456
    • Adams, S.H.1
  • 2
    • 0014304603 scopus 로고
    • Influence of dietary deprivations on plasma concentration of free amino acids of man
    • Adibi SA. Influence of dietary deprivations on plasma concentration of free amino acids of man. J Appl Physiol 25: 52-57, 1968.
    • (1968) J Appl Physiol , vol.25 , pp. 52-57
    • Adibi, S.A.1
  • 5
    • 0026097836 scopus 로고
    • Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes
    • Baquet A, Lavoinne A, Hue L. Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes. Biochem J 273: 57-62, 1991.
    • (1991) Biochem J , vol.273 , pp. 57-62
    • Baquet, A.1    Lavoinne, A.2    Hue, L.3
  • 7
    • 31544458134 scopus 로고    scopus 로고
    • Branched-chain amino acids: Enzyme and substrate regulation
    • Brosnan JT, Brosnan ME. Branched-chain amino acids: enzyme and substrate regulation. J Nutr 136: 207S-211S, 2006.
    • (2006) J Nutr , vol.136
    • Brosnan, J.T.1    Brosnan, M.E.2
  • 8
    • 0033848815 scopus 로고    scopus 로고
    • Regulation of expression of branched-chain alpha-keto acid dehydrogenase subunits in permanent cell lines
    • Chinsky JM, Costeas PA. Regulation of expression of branched-chain alpha-keto acid dehydrogenase subunits in permanent cell lines. Methods Enzymol 324: 479-490, 2000.
    • (2000) Methods Enzymol , vol.324 , pp. 479-490
    • Chinsky, J.M.1    Costeas, P.A.2
  • 9
    • 0020580021 scopus 로고
    • Induction of the branched-chain 2-oxo acid dehydrogenase complex in 3T3-L1 adipocytes during differentiation
    • Chuang DT, Hu CW, Patel MS. Induction of the branched-chain 2-oxo acid dehydrogenase complex in 3T3-L1 adipocytes during differentiation. Biochem J 214: 177-181, 1983.
    • (1983) Biochem J , vol.214 , pp. 177-181
    • Chuang, D.T.1    Hu, C.W.2    Patel, M.S.3
  • 10
    • 0029836227 scopus 로고    scopus 로고
    • Effects of insulin on the regulation of branched-chain alpha-keto acid dehydrogenase E1 alpha subunit gene expression
    • Costeas PA, Chinsky JM. Effects of insulin on the regulation of branched-chain alpha-keto acid dehydrogenase E1 alpha subunit gene expression. Biochem J 318: 85-92, 1996.
    • (1996) Biochem J , vol.318 , pp. 85-92
    • Costeas, P.A.1    Chinsky, J.M.2
  • 12
    • 0014669160 scopus 로고
    • Plasma amino acid levels and insulin secretion in obesity
    • Felig P, Marliss E, Cahill GF Jr. Plasma amino acid levels and insulin secretion in obesity. N Engl J Med 281: 811-816, 1969.
    • (1969) N Engl J Med , vol.281 , pp. 811-816
    • Felig, P.1    Marliss, E.2    Cahill Jr., G.F.3
  • 13
    • 78650732495 scopus 로고    scopus 로고
    • Plasma metabolomic profiles reflective of glucose homeostasis in nondiabetic and type 2 diabetic obese African-American women
    • Fiehn O, Garvey WT, Newman JW, Lok KH, Hoppel CL, Adams SH. Plasma metabolomic profiles reflective of glucose homeostasis in nondiabetic and type 2 diabetic obese African-American women. PLoS One 5: e15234, 2010.
    • (2010) PLoS One , vol.5
    • Fiehn, O.1    Garvey, W.T.2    Newman, J.W.3    Lok, K.H.4    Hoppel, C.L.5    Adams, S.H.6
  • 14
    • 84856597372 scopus 로고    scopus 로고
    • Metabolic characteristics of human subcutaneous abdominal adipose tissue after overnight fast
    • Frayn KN, Humphreys SM. Metabolic characteristics of human subcutaneous abdominal adipose tissue after overnight fast. Am J Physiol Endocrinol Metab 302: E468-E475, 2012.
    • (2012) Am J Physiol Endocrinol Metab , vol.302
    • Frayn, K.N.1    Humphreys, S.M.2
  • 15
    • 0025877124 scopus 로고
    • Amino acid metabolism in human subcutaneous adipose tissue in vivo
    • Frayn KN, Khan K, Coppack SW, Elia M. Amino acid metabolism in human subcutaneous adipose tissue in vivo. Clin Sci (Lond) 80: 471-474, 1991.
    • (1991) Clin Sci (Lond) , vol.80 , pp. 471-474
    • Frayn, K.N.1    Khan, K.2    Coppack, S.W.3    Elia, M.4
  • 16
    • 0020503936 scopus 로고
    • Leucine catabolism during the differentiation of 3T3-L1 cells. Expression of a mitochondrial enzyme system
    • Frerman FE, Sabran JL, Taylor JL, Grossberg SE. Leucine catabolism during the differentiation of 3T3-L1 cells. Expression of a mitochondrial enzyme system. J Biol Chem 258: 7087-7093, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 7087-7093
    • Frerman, F.E.1    Sabran, J.L.2    Taylor, J.L.3    Grossberg, S.E.4
  • 17
    • 0019308961 scopus 로고
    • Insulin regulation of branched-chain alphaketo acid dehydrogenase in adipose tissue
    • Frick GP, Goodman HM. Insulin regulation of branched-chain alphaketo acid dehydrogenase in adipose tissue. J Biol Chem 255: 6186-6192, 1980.
    • (1980) J Biol Chem , vol.255 , pp. 6186-6192
    • Frick, G.P.1    Goodman, H.M.2
  • 18
    • 0024516636 scopus 로고
    • Insulin regulation of the activity and phosphorylation of branched-chain 2-oxo acid dehydrogenase in adipose tissue
    • Frick GP, Goodman HM. Insulin regulation of the activity and phosphorylation of branched-chain 2-oxo acid dehydrogenase in adipose tissue. Biochem J 258: 229-235, 1989.
    • (1989) Biochem J , vol.258 , pp. 229-235
    • Frick, G.P.1    Goodman, H.M.2
  • 19
    • 0019395350 scopus 로고
    • L-Leucine activates branched-chain alpha-keto acid dehydrogenase in rat adipose tissue
    • Frick GP, Tai LR, Blinder L, Goodman HM. L-Leucine activates branched-chain alpha-keto acid dehydrogenase in rat adipose tissue. J Biol Chem 256: 2618-2620, 1981.
    • (1981) J Biol Chem , vol.256 , pp. 2618-2620
    • Frick, G.P.1    Tai, L.R.2    Blinder, L.3    Goodman, H.M.4
  • 21
    • 0017688331 scopus 로고
    • Site of action of insulin in promoting leucine utilization in adipose tissue
    • Goodman HM. Site of action of insulin in promoting leucine utilization in adipose tissue. Am J Physiol Endocrinol Metab Gastrointest Physiol 233: E97-E103, 1977.
    • (1977) Am J Physiol Endocrinol Metab Gastrointest Physiol , vol.233
    • Goodman, H.M.1
  • 22
    • 77951232682 scopus 로고    scopus 로고
    • Adipose tissue branched-chain amino acid (BCAA) metabolism modulates circulating BCAA levels
    • Herman MA, She P, Peroni OD, Lynch CJ, Kahn BB. Adipose tissue branched-chain amino acid (BCAA) metabolism modulates circulating BCAA levels. J Biol Chem 285: 11348-11356, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 11348-11356
    • Herman, M.A.1    She, P.2    Peroni, O.D.3    Lynch, C.J.4    Kahn, B.B.5
  • 26
    • 67649235962 scopus 로고    scopus 로고
    • Determination of branched-chain amino acids, methionine, phenylalanine, tyrosine and alpha-keto acids in plasma and dried blood samples using HPLC with fluorescence detection
    • Kand'ar R, Zakova P, Jirosova J, Sladka M. Determination of branched-chain amino acids, methionine, phenylalanine, tyrosine and alpha-keto acids in plasma and dried blood samples using HPLC with fluorescence detection. Clin Chem Lab Med 47: 565-572, 2009.
    • (2009) Clin Chem Lab Med , vol.47 , pp. 565-572
    • Kand'ar, R.1    Zakova, P.2    Jirosova, J.3    Sladka, M.4
  • 27
    • 0028110437 scopus 로고
    • Coordinated expression of valine catabolic enzymes during adipogenesis: Analysis of activity, mRNA, protein levels, and metabolic consequences
    • Kedishvili NY, Popov KM, Jaskiewicz JA, Harris RA. Coordinated expression of valine catabolic enzymes during adipogenesis: analysis of activity, mRNA, protein levels, and metabolic consequences. Arch Biochem Biophys 315: 317-322, 1994.
    • (1994) Arch Biochem Biophys , vol.315 , pp. 317-322
    • Kedishvili, N.Y.1    Popov, K.M.2    Jaskiewicz, J.A.3    Harris, R.A.4
  • 28
    • 0028013303 scopus 로고
    • Production of glutamine and utilization of glutamate by rat subcutaneous adipose tissue in vivo
    • Kowalski TJ, Watford M. Production of glutamine and utilization of glutamate by rat subcutaneous adipose tissue in vivo. Am J Physiol Endocrinol Metab 266: E151-E154, 1994.
    • (1994) Am J Physiol Endocrinol Metab , vol.266
    • Kowalski, T.J.1    Watford, M.2
  • 29
    • 33745332711 scopus 로고    scopus 로고
    • Rat adipose tissue amino acid metabolism in vivo as assessed by microdialysis and arteriovenous techniques
    • Kowalski TJ, Wu G, Watford M. Rat adipose tissue amino acid metabolism in vivo as assessed by microdialysis and arteriovenous techniques. Am J Physiol Endocrinol Metab 273: E613-E622, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Kowalski, T.J.1    Wu, G.2    Watford, M.3
  • 31
    • 24944489239 scopus 로고    scopus 로고
    • Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: Increased expression of inflammation-related genes
    • Lee YH, Nair S, Rousseau E, Allison DB, Page GP, Tataranni PA, Bogardus C, Permana PA. Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes. Diabetologia 48: 1776-1783, 2005.
    • (2005) Diabetologia , vol.48 , pp. 1776-1783
    • Lee, Y.H.1    Nair, S.2    Rousseau, E.3    Allison, D.B.4    Page, G.P.5    Tataranni, P.A.6    Bogardus, C.7    Permana, P.A.8
  • 32
    • 58249138618 scopus 로고    scopus 로고
    • Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus
    • Li X, Xu Z, Lu X, Yang X, Yin P, Kong H, Yu Y, Xu G. Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: biomarker discovery for diabetes mellitus. Anal Chim Acta 633: 257-262, 2009.
    • (2009) Anal Chim Acta , vol.633 , pp. 257-262
    • Li, X.1    Xu, Z.2    Lu, X.3    Yang, X.4    Yin, P.5    Kong, H.6    Yu, Y.7    Xu, G.8
  • 35
    • 0029741256 scopus 로고    scopus 로고
    • Copper absorption, endogenous excretion, and distribution in Sprague-Dawley and lean (Fa/ Fa) Zucker rats
    • Miller GD, Keen CL, Stern JS, Uriu-Hare JY. Copper absorption, endogenous excretion, and distribution in Sprague-Dawley and lean (Fa/ Fa) Zucker rats. Biol Trace Elem Res 53: 261-279, 1996.
    • (1996) Biol Trace Elem Res , vol.53 , pp. 261-279
    • Miller, G.D.1    Keen, C.L.2    Stern, J.S.3    Uriu-Hare, J.Y.4
  • 39
    • 0016166002 scopus 로고
    • Metabolic fate of leucine: A significant sterol precursor in adipose tissue and muscle
    • Rosenthal J, Angel A, Farkas J. Metabolic fate of leucine: a significant sterol precursor in adipose tissue and muscle. Am J Physiol 226: 411-418, 1974.
    • (1974) Am J Physiol , vol.226 , pp. 411-418
    • Rosenthal, J.1    Angel, A.2    Farkas, J.3
  • 43
    • 37149027613 scopus 로고    scopus 로고
    • Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
    • She P, Van Horn C, Reid T, Hutson SM, Cooney RN, Lynch CJ. Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism. Am J Physiol Endocrinol Metab 293: E1552-E1563, 2007.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • She, P.1    van Horn, C.2    Reid, T.3    Hutson, S.M.4    Cooney, R.N.5    Lynch, C.J.6
  • 45
    • 79958199093 scopus 로고    scopus 로고
    • Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women
    • Thomas AP, Dunn TN, Oort PJ, Grino M, Adams SH. Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women. J Nutr 141: 1172-1180, 2011.
    • (2011) J Nutr , vol.141 , pp. 1172-1180
    • Thomas, A.P.1    Dunn, T.N.2    Oort, P.J.3    Grino, M.4    Adams, S.H.5
  • 47
    • 0019167228 scopus 로고
    • Leucine degradation and release of glutamine and alanine by adipose tissue
    • Tischler ME, Goldberg AL. Leucine degradation and release of glutamine and alanine by adipose tissue. J Biol Chem 255: 8074-8081, 1980.
    • (1980) J Biol Chem , vol.255 , pp. 8074-8081
    • Tischler, M.E.1    Goldberg, A.L.2
  • 52
    • 42249111525 scopus 로고    scopus 로고
    • 2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition
    • Zhong D, Liu X, Schafer-Hales K, Marcus AI, Khuri FR, Sun SY, Zhou W. 2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition. Mol Cancer Ther 7: 809-817, 2008.
    • (2008) Mol Cancer Ther , vol.7 , pp. 809-817
    • Zhong, D.1    Liu, X.2    Schafer-Hales, K.3    Marcus, A.I.4    Khuri, F.R.5    Sun, S.Y.6    Zhou, W.7


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