Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds

Toxicological Sciences

Volumn 117, Issue 1, 2010, Pages 81-89

  Vandebriel, Rob J ^a   Pennings, Jeroen L A ^a   Baken, Kirsten A ^b   Pronk, Tessa E ^a,b   Boorsma, Andre ^c   Gottschalk, Ralph ^b   Van Loveren, Henk ^a,b  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c TNO   (Netherlands)

Author keywords

Gene profiling; HaCaT; Irritant oxidative stress; Keratinocytes; Sensitizer

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 2 PROPANOL; BENZOIC ACID; CINNAMYL ALCOHOL; COLLAGEN TYPE 16; DISULFIRAM; DODECYL SULFATE SODIUM; EUGENOL; FERRITIN; FERROCHELATASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCURONOSYLTRANSFERASE 1A6; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE REDUCTASE; HEAT SHOCK PROTEIN; HEME OXYGENASE 1; HEXANE; INTERLEUKIN 6 RECEPTOR; IRRITANT AGENT; ISOEUGENOL; LACTIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; NICKEL SULFATE; PHOSPHOGLUCONATE DEHYDROGENASE; SALICYLIC ACID METHYL ESTER; THIOREDOXIN 2; THIOREDOXIN REDUCTASE 1; THIOREDOXIN REDUCTASE 2; TRANSCRIPTION FACTOR NRF2;

ARTICLE; CELL VIABILITY; GENE CONTROL; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; KERATINOCYTE; OXIDATIVE STRESS; RANDOM FOREST; SENSITIZATION; SUPPORT VECTOR MACHINE;

CELL LINE; GENE EXPRESSION PROFILING; HUMANS; IRRITANTS; KERATINOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS;

ANIMALIA;

EID: 77955871452     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq182     Document Type: Article

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