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Volumn 68, Issue 1, 2013, Pages 32-41

What determines skin sensitization potency-myths, maybes and realities. Part 1. the 500 molecular weight cut-off

Author keywords

bioavailability; molecular weight; penetration; sensitization; structure activity

Indexed keywords

1,1,3 TRIS(2 METHYL 4 HYDROXY 5 TERT BUTYLPHENYL)BUTANE; 1,2,5,6,9,10 HEXABROMOCYCLODODECANE; 3 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL)PROPIONIC ACID OCTADECYL ESTER; 3,4 EPOXYCLOHEXYLETHYLCYCLOPOLYMETHYLSILOXANE; ACID RED 18; BISPHENOL A BIS(2 HYDROXYPROPYL) ETHER DIMETHACRYLATE; CHEMICAL COMPOUND; CONTACT ALLERGEN; DIISOSTEARYL MALATE; DILAURYL THIODIPROPIONATE; DIMETHYLDIOCTADECYLAMMONIUM CHLORIDE; MACROGOL; MADECASSIC ACID; METHYLENE DISTEARAMIDE; TRIS(2 ETHYLHEXYL)BENZENE 1,2,4 TRICARBOXYLATE; UNCLASSIFIED DRUG;

EID: 84870899568     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/j.1600-0536.2012.02160.x     Document Type: Article
Times cited : (22)

References (22)
  • 1
    • 79952041429 scopus 로고    scopus 로고
    • The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: Results of a ring-study in five laboratories
    • Natsch A, Bauch C, Foertsch L, et al., The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: results of a ring-study in five laboratories. Toxicol In Vitro 2011: 25: 733-744.
    • (2011) Toxicol in Vitro , vol.25 , pp. 733-744
    • Natsch, A.1    Bauch, C.2    Foertsch, L.3
  • 3
    • 49949107704 scopus 로고    scopus 로고
    • The use of patch tests in determining hypersensitivity to etanercept and infliximab
    • Lecluse L, Piskin G, Bos J., The use of patch tests in determining hypersensitivity to etanercept and infliximab. Arch Dermatol 2008: 144: 1070-1071.
    • (2008) Arch Dermatol , vol.144 , pp. 1070-1071
    • Lecluse, L.1    Piskin, G.2    Bos, J.3
  • 5
    • 0037568064 scopus 로고    scopus 로고
    • Studies of chemical selectivity of hapten, reactivity, and skin sensitization. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitisers, 5-chloro-2-methylisothiazol-3- one (MCI) and 2 methylisothiazol-3-one (MI)
    • Alvarez-Sanchez R, Basketter D, Pease C, Lepoittevin J-P., Studies of chemical selectivity of hapten, reactivity, and skin sensitization. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitisers, 5-chloro-2-methylisothiazol-3-one (MCI) and 2 methylisothiazol-3- one (MI). Chem Res Toxicol 2003: 16: 627-636.
    • (2003) Chem Res Toxicol , vol.16 , pp. 627-636
    • Alvarez-Sanchez, R.1    Basketter, D.2    Pease, C.3    Lepoittevin, J.-P.4
  • 6
    • 13844265990 scopus 로고    scopus 로고
    • From experiment to theory: Molecular orbital parameters to interpret the skin sensitization potential of 5-chloro-2-methylisothiazol-3-one and 2-methylisothiazol-3-one
    • Aptula A, Roberts D W, Cronin M., From experiment to theory: molecular orbital parameters to interpret the skin sensitization potential of 5-chloro-2-methylisothiazol-3-one and 2-methylisothiazol-3-one. Chem Res Toxicol 2005: 18: 324-329.
    • (2005) Chem Res Toxicol , vol.18 , pp. 324-329
    • Aptula, A.1    Roberts, D.W.2    Cronin, M.3
  • 7
    • 0002093068 scopus 로고    scopus 로고
    • Hapten-protein interactions
    • Lepoittevin J-P, Basketter D. A, Goosens A. Karlberg A-T (eds): Heidelberg, Springer
    • Roberts D W, Lepoittevin J-P., Hapten-protein interactions. In: Allergic Contact Dermatitis. The Molecular Basis, Lepoittevin J-P, Basketter D A, Goosens A, Karlberg A-T, (eds): Heidelberg, Springer, 1997: pp. 81-111.
    • (1997) Allergic Contact Dermatitis. The Molecular Basis , pp. 81-111
    • Roberts, D.W.1    Lepoittevin, J.-P.2
  • 8
    • 34249709530 scopus 로고    scopus 로고
    • TIMES-SS - A promising tool for the assessment of skin sensitization hazard. A characterization with respect to the OECD validation principles for (Q)SARs and an external evaluation for predictivity
    • Patlewicz G, Dimitrov S D, Low L K et al., TIMES-SS-a promising tool for the assessment of skin sensitization hazard. A characterization with respect to the OECD validation principles for (Q)SARs and an external evaluation for predictivity. Regul Toxicol Pharmacol 2007: 48: 225-239.
    • (2007) Regul Toxicol Pharmacol , vol.48 , pp. 225-239
    • Patlewicz, G.1    Dimitrov, S.D.2    Low, L.K.3
  • 9
    • 76149142138 scopus 로고    scopus 로고
    • Local lymph node data for the evaluation of skin sensitization alternatives: A second compilation
    • Kern P S, Gerberick F, Ryan C A, Kimber I, Aptula A O, Basketter D A., Local lymph node data for the evaluation of skin sensitization alternatives: a second compilation. Dermatitis 2010: 21: 8-32.
    • (2010) Dermatitis , vol.21 , pp. 8-32
    • Kern, P.S.1    Gerberick, F.2    Ryan, C.A.3    Kimber, I.4    Aptula, A.O.5    Basketter, D.A.6
  • 10
    • 35649009496 scopus 로고    scopus 로고
    • Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro
    • Natsch A, Gfeller H, Rothaupt M, Ellis G., Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro. Toxicol In Vitro 2007: 21: 1220-1226.
    • (2007) Toxicol in Vitro , vol.21 , pp. 1220-1226
    • Natsch, A.1    Gfeller, H.2    Rothaupt, M.3    Ellis, G.4
  • 11
    • 0028191789 scopus 로고
    • Multivariate QSAR analysis of a skin sensitization database
    • Cronin M T, Basketter D A., Multivariate QSAR analysis of a skin sensitization database. SAR QSAR Environ Res 1994: 2: 159-179.
    • (1994) SAR QSAR Environ Res , vol.2 , pp. 159-179
    • Cronin, M.T.1    Basketter, D.A.2
  • 12
    • 33846889946 scopus 로고    scopus 로고
    • Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse local lymph node assay
    • Roberts D W, Aptula A O, Patlewicz G., Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse local lymph node assay. Chem Res Toxicol 2007: 20: 44-60.
    • (2007) Chem Res Toxicol , vol.20 , pp. 44-60
    • Roberts, D.W.1    Aptula, A.O.2    Patlewicz, G.3
  • 13
    • 0026069596 scopus 로고
    • Allergic contact dermatitis from eosin
    • Tomb R., Allergic contact dermatitis from eosin. Contact Dermatitis 1991: 24: 27-29.
    • (1991) Contact Dermatitis , vol.24 , pp. 27-29
    • Tomb, R.1
  • 14
    • 35848943030 scopus 로고    scopus 로고
    • Are concomitant patch test reactions to epoxy resin and BIS-GMA indicative of cross-reactivity?
    • Geier J, Lessmann H, Uter W, Schnuch A., Are concomitant patch test reactions to epoxy resin and BIS-GMA indicative of cross-reactivity? Contact Dermatitis 2007: 57: 376-380.
    • (2007) Contact Dermatitis , vol.57 , pp. 376-380
    • Geier, J.1    Lessmann, H.2    Uter, W.3    Schnuch, A.4
  • 15
  • 17
    • 0034098046 scopus 로고    scopus 로고
    • The 500 Dalton rule for the skin penetration of chemical compounds and drugs
    • Bos J D, Meinardi M M H M., The 500 Dalton rule for the skin penetration of chemical compounds and drugs. Exp Dermatol 2000: 9: 165-169.
    • (2000) Exp Dermatol , vol.9 , pp. 165-169
    • Bos, J.D.1    Meinardi, M.M.H.M.2
  • 18
    • 0037362487 scopus 로고    scopus 로고
    • Contact allergy: The role of skin chemistry and metabolism
    • Smith-Pease K, Basketter D, Patlewicz G., Contact allergy: the role of skin chemistry and metabolism. Clin Exp Dermatol 2003: 2: 177-183.
    • (2003) Clin Exp Dermatol , vol.2 , pp. 177-183
    • Smith-Pease, K.1    Basketter, D.2    Patlewicz, G.3
  • 19
    • 34247135041 scopus 로고    scopus 로고
    • Skin sensitisation and epidermal disposition: The relevance of epidermal disposition for sensitisation hazard identification and risk assessment. The report of ECVAM workshop 59
    • Basketter D, Pease C, Kasting G et al., Skin sensitisation and epidermal disposition: the relevance of epidermal disposition for sensitisation hazard identification and risk assessment. The report of ECVAM workshop 59. Altern Lab Anim 2007: 35: 137-154.
    • (2007) Altern Lab Anim , vol.35 , pp. 137-154
    • Basketter, D.1    Pease, C.2    Kasting, G.3
  • 20
    • 42049110135 scopus 로고    scopus 로고
    • Determinants of skin sensitisation potential
    • Roberts D W, Aptula A O., Determinants of skin sensitisation potential. J Appl Toxicol 2008: 28: 377-387.
    • (2008) J Appl Toxicol , vol.28 , pp. 377-387
    • Roberts, D.W.1    Aptula, A.O.2
  • 21
    • 84859779633 scopus 로고    scopus 로고
    • Skin penetration
    • In Johansen J. D, Frosch P. J, Lepoittevin J-P. (eds):, Berlin Heidelberg, Springer-Verlag
    • Schaefer H, Redelmeier T, Ledemann J., Skin penetration. In, Johansen J D, Frosch P J, Lepoittevin J-P., (eds): Contact Dermatitis, Berlin Heidelberg, Springer-Verlag, 2011: pp. 215-225.
    • (2011) Contact Dermatitis , pp. 215-225
    • Schaefer, H.1    Redelmeier, T.2    Ledemann, J.3
  • 22
    • 79959830352 scopus 로고    scopus 로고
    • Interconversion between local lymph node assay EC3 units
    • Roberts D W., Interconversion between local lymph node assay EC3 units. Contact Dermatitis 2011: 65: 59.
    • (2011) Contact Dermatitis , vol.65 , pp. 59
    • Roberts, D.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.