Squaric acid mediated synthesis and biological activity of a library of linear and hyperbranched poly(glycerol)-protein conjugates

Biomacromolecules

Volumn 13, Issue 4, 2012, Pages 1161-1171

  Wurm, Frederik ^a   Dingels, Carsten ^b   Frey, Holger ^b   Klok, Harm Anton ^a  

^a EPFL   (Switzerland)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYL ESTER; HYDROXYL SIDES; HYPERBRANCHED; HYPERBRANCHED POLYGLYCEROL; LINEAR POLYMERS; LOW MOLECULAR WEIGHT; NON-ORTHOGONALITY; POLYGLYCEROLS; POLYMER CONJUGATE; POLYMER-PROTEIN CONJUGATES; PROTEIN CONJUGATES; SIDE REACTIONS; SIDE-CHAINS; SQUARIC ACIDS; STRUCTURE ACTIVITY RELATIONSHIPS; SYNTHETIC POLYMERS;

BIOACTIVITY; BIOSYNTHESIS; COPOLYMERS; ENZYMES; FUNCTIONAL GROUPS; FUNCTIONAL POLYMERS; GLYCEROL; MOLECULAR WEIGHT; PROTEINS;

DENDRIMERS;

AMINE; BOVINE SERUM ALBUMIN; HYDROXYL GROUP; LYSOZYME; POLYGLYCEROL; POLYMER; PROTEIN; SQUARIC ACID DERIVATIVE; SQUARIC ACID DIETHYL ESTER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CROSS COUPLING REACTION; DRUG ACTIVITY; DRUG CONJUGATION; DRUG SYNTHESIS; FEASIBILITY STUDY; HYDROLYSIS; MEDIATOR; MOLECULAR WEIGHT; PEPTIDE LIBRARY; POLYMERIZATION; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

CYCLOBUTANES; GLYCEROL; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; MURAMIDASE; POLYMERS; SERUM ALBUMIN, BOVINE; SMALL MOLECULE LIBRARIES;

EID: 84860734524     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm300103u     Document Type: Article

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