Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro

Archives of Toxicology

Volumn 87, Issue 9, 2013, Pages 1683-1696

  Fabian, E ^a,b   Vogel, D ^b   Blatz, V ^a   Ramirez, T ^a   Kolle, S ^a   Eltze, T ^a   Van Ravenzwaay, B ^a   Oesch, F ^c   Landsiedel, R ^a  

^a BASF SE   (Germany)

^b Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Human dendritic cell lines; Human keratinocytic cell lines; Xenobiotic metabolizing enzymes

Indexed keywords

4 AMINOBENZOIC ACID ESTER; 7 BENZYLRESORUFIN O DEBENZYLASE; ACYLTRANSFERASE; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CELL ENZYME; DIMETHYLANILINE MONOOXYGENASE; ESTERASE; ETHOXYRESORUFIN DEETHYLASE; GLUCURONOSYLTRANSFERASE; MESSENGER RNA; N ACETYLTRANSFERASE 1; PENTOXYRESORUFIN DEALKYLASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNCLASSIFIED DRUG; UNCLASSIFIED ENZYME; XENOBIOTIC METABOLIZING ENZYME;

ACETYLATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSOLIC FRACTION; DENDRITIC CELL; DETOXIFICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKIN SENSITIZATION;

ACETYLATION; ANIMAL USE ALTERNATIVES; ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; CELL LINE; COSMETICS; CYTOSOL; DENDRITIC CELLS; DERMATITIS, ALLERGIC CONTACT; HUMANS; ISOENZYMES; KERATINOCYTES; LIMIT OF DETECTION; MALE; MICROSOMES; MICROSOMES, LIVER; RATS; RATS, WISTAR; SKIN; TOXICITY TESTS; XENOBIOTICS;

EID: 84883551884     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1090-9     Document Type: Article

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