-
1
-
-
0027443904
-
Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
-
Abdel-Razzak, Z., Loyer, P., Fautrel, A., Gautier, J. C., Corcos, L., Turlin, B., Beaune, P., and Guillouzo, A. 1993. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol. 44:707-715.
-
(1993)
Mol. Pharmacol
, vol.44
, pp. 707-715
-
-
Abdel-Razzak, Z.1
Loyer, P.2
Fautrel, A.3
Gautier, J.C.4
Corcos, L.5
Turlin, B.6
Beaune, P.7
Guillouzo, A.8
-
2
-
-
0041816286
-
Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide
-
Atmane, N., Dairou, J., Paul, A., Dupret, J. M., and Rodrigues-Lima, F. 2003. Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide. J Biol. Chem. 278:35086-35092.
-
(2003)
J Biol. Chem
, vol.278
, pp. 35086-35092
-
-
Atmane, N.1
Dairou, J.2
Paul, A.3
Dupret, J.M.4
Rodrigues-Lima, F.5
-
3
-
-
0028879678
-
Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder
-
Badawi, A. F., Hirvonen, A., Bell, D. A., Lang, N. P., and Kadlubar, F. F. 1995. Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder. Cancer Res. 55:5230-5237.
-
(1995)
Cancer Res
, vol.55
, pp. 5230-5237
-
-
Badawi, A.F.1
Hirvonen, A.2
Bell, D.A.3
Lang, N.P.4
Kadlubar, F.F.5
-
4
-
-
33746871427
-
Bioactivation, protein haptenation, and toxicity of sulfamethoxazole and dapsone in normal human dermal fibroblasts
-
Bhaiya, P., Roychowdhury, S., Vyas, P. M., Doll, M. A., Hein, D. W., and Svensson, C. K. 2006. Bioactivation, protein haptenation, and toxicity of sulfamethoxazole and dapsone in normal human dermal fibroblasts. Toxicol. Appl. Pharmacol. 215:158-167.
-
(2006)
Toxicol. Appl. Pharmacol
, vol.215
, pp. 158-167
-
-
Bhaiya, P.1
Roychowdhury, S.2
Vyas, P.M.3
Doll, M.A.4
Hein, D.W.5
Svensson, C.K.6
-
5
-
-
0025344002
-
Human arylamine N-acetyltransferase genes: Isolation, chromosomal localization, and functional expression
-
Blum, M., Grant, D. M., McBride, W., Heim, M., and Meyer, U. A. 1990. Human arylamine N-acetyltransferase genes: Isolation, chromosomal localization, and functional expression. DNA Cell Biol. 9:193-203.
-
(1990)
DNA Cell Biol
, vol.9
, pp. 193-203
-
-
Blum, M.1
Grant, D.M.2
McBride, W.3
Heim, M.4
Meyer, U.A.5
-
6
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
-
(1976)
Anal. Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
7
-
-
0345240943
-
Correlation between genotype and phenotype of the human arylamine N- acetyltransferase type 1 (NAT1)
-
Bruhn, C., Brockmöller, J., Cascorbi, I., Roots, I., and Borchert, H. H. 1999. Correlation between genotype and phenotype of the human arylamine N- acetyltransferase type 1 (NAT1). Biochem. Pharmacol. 58:1759-1764.
-
(1999)
Biochem. Pharmacol
, vol.58
, pp. 1759-1764
-
-
Bruhn, C.1
Brockmöller, J.2
Cascorbi, I.3
Roots, I.4
Borchert, H.H.5
-
8
-
-
0034050341
-
Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells
-
Butcher, N. J., Ilett, K. F., and Minchin, R. F. 2000. Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells. Mol. Pharmacol. 57:468-473.
-
(2000)
Mol. Pharmacol
, vol.57
, pp. 468-473
-
-
Butcher, N.J.1
Ilett, K.F.2
Minchin, R.F.3
-
9
-
-
0027237228
-
Arylamine N-acetyltransferase activity in human cultured cell lines
-
Coroneos, E., and Sim, E. 1993. Arylamine N-acetyltransferase activity in human cultured cell lines. Biochem. J. 294:481-486.
-
(1993)
Biochem. J
, vol.294
, pp. 481-486
-
-
Coroneos, E.1
Sim, E.2
-
10
-
-
0026335694
-
Expression of monomorphic arylamine N-acetyltransferase (NAT1) in human leukocytes
-
Cribb, A. E., Grant, D. M., Miller, M. A., and Spielberg, S. P. 1991. Expression of monomorphic arylamine N-acetyltransferase (NAT1) in human leukocytes. J Pharmacol. Exp. Ther. 259:1241-1246.
-
(1991)
J Pharmacol. Exp. Ther
, vol.259
, pp. 1241-1246
-
-
Cribb, A.E.1
Grant, D.M.2
Miller, M.A.3
Spielberg, S.P.4
-
11
-
-
15744370426
-
The xenobiotic-metabolizing enzymes arylamine N-acetyltransferases in human lens epithelial cells: Inactivation by cellular oxidants and UVB-induced oxidative stress
-
Dairou, J., Malecaze, F., Dupret, J. M., and Rodrigues-Lima, F. 2005. The xenobiotic-metabolizing enzymes arylamine N-acetyltransferases in human lens epithelial cells: inactivation by cellular oxidants and UVB-induced oxidative stress. Mol. Pharmacol. 67:1299-1306.
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 1299-1306
-
-
Dairou, J.1
Malecaze, F.2
Dupret, J.M.3
Rodrigues-Lima, F.4
-
12
-
-
0026713308
-
Sequences and expression of alleles of polymorphic arylamine N- acetyltransferase of human liver
-
Deguchi, T. 1992. Sequences and expression of alleles of polymorphic arylamine N- acetyltransferase of human liver. J. Biol. Chem. 267:18140-18147.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 18140-18147
-
-
Deguchi, T.1
-
13
-
-
0031969231
-
Expression of arylamine N-acetyltransferase in human intestine
-
Hickman, D., Pope, J., Patil, S. D., Fakis, G., Smelt, V., Stanley, L. A., Payton, M., Unadkat, J. D., and Sim, E. 1998. Expression of arylamine N-acetyltransferase in human intestine. Gut 42:402-409.
-
(1998)
Gut
, vol.42
, pp. 402-409
-
-
Hickman, D.1
Pope, J.2
Patil, S.D.3
Fakis, G.4
Smelt, V.5
Stanley, L.A.6
Payton, M.7
Unadkat, J.D.8
Sim, E.9
-
14
-
-
3242787887
-
Identification of the major promoter and non-coding exons of the human arylamine N-acetyltransferase 1 gene (NAT1)
-
Husain, A., Barker, D. F., States, J. C., Doll, M. A., and Hein, D. W. 2004. Identification of the major promoter and non-coding exons of the human arylamine N-acetyltransferase 1 gene (NAT1). Pharmacogenetics 14:397-406.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 397-406
-
-
Husain, A.1
Barker, D.F.2
States, J.C.3
Doll, M.A.4
Hein, D.W.5
-
15
-
-
0033958152
-
N-Acetylation of paraphenylenediamine in human skin and keratinocytes
-
Kawakubo, Y., Merk, H. F., Masaoudi, T. A., Sieben, S., and Blömeke, B. 2000. N-Acetylation of paraphenylenediamine in human skin and keratinocytes. J. Pharmacol. Exp. Ther. 292:150-155.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.292
, pp. 150-155
-
-
Kawakubo, Y.1
Merk, H.F.2
Masaoudi, T.A.3
Sieben, S.4
Blömeke, B.5
-
16
-
-
0028556579
-
Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells
-
Kloth, M. T., Gee, R. L., Messing, E. M., and Swaminathan, S. 1994. Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells. Carcinogenesis 15:2781-2787.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2781-2787
-
-
Kloth, M.T.1
Gee, R.L.2
Messing, E.M.3
Swaminathan, S.4
-
17
-
-
23044517246
-
Under the skin: Biotransformation of para-aminophenol and para-phenylenediamine in reconstructed human epidermis and human hepatocytes
-
Nohynek, G. J., Duche, D., Garrigues, A., Meunier, P. A., Toutain, H., and Leclaire, J. 2005. Under the skin: Biotransformation of para-aminophenol and para-phenylenediamine in reconstructed human epidermis and human hepatocytes. Toxicol. Lett. 158:196-212.
-
(2005)
Toxicol. Lett
, vol.158
, pp. 196-212
-
-
Nohynek, G.J.1
Duche, D.2
Garrigues, A.3
Meunier, P.A.4
Toutain, H.5
Leclaire, J.6
-
18
-
-
0029934427
-
N-Acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland
-
Sadrieh, N., Davis, C. D., and Snyderwine, E. G. 1996. N-Acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland. Cancer Res. 56:2683-2687.
-
(1996)
Cancer Res
, vol.56
, pp. 2683-2687
-
-
Sadrieh, N.1
Davis, C.D.2
Snyderwine, E.G.3
-
19
-
-
34247552226
-
Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling
-
Sanderson, J. P., Naisbitt, D. J., Farrell, J., Ashby, C. A., Tucker, M. J., Rieder, M. J., Pirmohamed, M., Clarke, S. E., and Park, B. K. 2007. Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling. J. Immunol. 178:5533-5542.
-
(2007)
J. Immunol
, vol.178
, pp. 5533-5542
-
-
Sanderson, J.P.1
Naisbitt, D.J.2
Farrell, J.3
Ashby, C.A.4
Tucker, M.J.5
Rieder, M.J.6
Pirmohamed, M.7
Clarke, S.E.8
Park, B.K.9
-
20
-
-
0032964232
-
Multiple cytochrome P450-isoenzymes mRNA are expressed in dendritic cells
-
Sieben, S., Baron, J. M., Blomeke, B., and Merk, H. F. 1999. Multiple cytochrome P450-isoenzymes mRNA are expressed in dendritic cells. Int. Arch. Allergy Immunol. 118:358-361.
-
(1999)
Int. Arch. Allergy Immunol
, vol.118
, pp. 358-361
-
-
Sieben, S.1
Baron, J.M.2
Blomeke, B.3
Merk, H.F.4
-
21
-
-
0032053328
-
Purification, characterization, and crystallization of an N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium. Protein Exp
-
Sinclair, J. C., Delgoda, R., Noble, M. E., Jarmin, S., Goh, N. K., and Sim, E. 1998. Purification, characterization, and crystallization of an N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium. Protein Exp. Purification. 12:371-380.
-
(1998)
Purification
, vol.12
, pp. 371-380
-
-
Sinclair, J.C.1
Delgoda, R.2
Noble, M.E.3
Jarmin, S.4
Goh, N.K.5
Sim, E.6
-
22
-
-
0031769199
-
Placental expression of arylamine N-acetyltransferases: Evidence for linkage disequilibrium between NAT1*10 and NAT2*4 alleles of the two human arylamine N-acetyltransferase loci NAT1 and NAT2
-
Smelt, V. A., Mardon, H. J., and Sim, E. 1998. Placental expression of arylamine N-acetyltransferases: Evidence for linkage disequilibrium between NAT1*10 and NAT2*4 alleles of the two human arylamine N-acetyltransferase loci NAT1 and NAT2. Pharmacol. Toxicol. 83:149-157.
-
(1998)
Pharmacol. Toxicol
, vol.83
, pp. 149-157
-
-
Smelt, V.A.1
Mardon, H.J.2
Sim, E.3
-
23
-
-
0029812630
-
Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder
-
Stanley, L. A., Coroneos, E., Cuff, R., Hickman, D., Ward, A., and Sim, E. 1996. Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder. J. Histochem. Cytochem. 44:1059-1067.
-
(1996)
J. Histochem. Cytochem
, vol.44
, pp. 1059-1067
-
-
Stanley, L.A.1
Coroneos, E.2
Cuff, R.3
Hickman, D.4
Ward, A.5
Sim, E.6
-
24
-
-
17144430460
-
Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes
-
Stanley, L. A., Skare, J. A., Doyle, E., Powrie, R., D'Angelo, D., and Elcombe, C. R. 2005. Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes. Toxicology 210:147-157.
-
(2005)
Toxicology
, vol.210
, pp. 147-157
-
-
Stanley, L.A.1
Skare, J.A.2
Doyle, E.3
Powrie, R.4
D'Angelo, D.5
Elcombe, C.R.6
-
25
-
-
0026674776
-
Arylamine N-acetyltransferase in human red blood cells
-
Ward, A., Hickman, D., Gordon, J. W., and Sim, E. 1992. Arylamine N-acetyltransferase in human red blood cells. Biochem. Pharmacol. 44:1099-1104.
-
(1992)
Biochem. Pharmacol
, vol.44
, pp. 1099-1104
-
-
Ward, A.1
Hickman, D.2
Gordon, J.W.3
Sim, E.4
-
26
-
-
0034102210
-
Localization of N-acetyltransferases NAT1 and NAT2 in human tissues
-
Windmill, K. F., Gaedigk, A., Hall, P. M., Samaratunga, H., Grant, D. M., and McManus, M. E. 2000. Localization of N-acetyltransferases NAT1 and NAT2 in human tissues. Toxicol. Sci. 54:19-29.
-
(2000)
Toxicol. Sci
, vol.54
, pp. 19-29
-
-
Windmill, K.F.1
Gaedigk, A.2
Hall, P.M.3
Samaratunga, H.4
Grant, D.M.5
McManus, M.E.6
-
27
-
-
33746675685
-
Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation
-
Zhou, C., Tabb, M. M., Nelson, E. L., Grun, F., Verma, S., Sadatrafiei, A., Lin, M., Mallick, S., Forman, B. M., Thummel, K. E., and Blumberg, B. 2006. Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J. Clin. Invest. 116:2280-2289.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2280-2289
-
-
Zhou, C.1
Tabb, M.M.2
Nelson, E.L.3
Grun, F.4
Verma, S.5
Sadatrafiei, A.6
Lin, M.7
Mallick, S.8
Forman, B.M.9
Thummel, K.E.10
Blumberg, B.11
|