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Volumn 36, Issue 12, 2008, Pages 2452-2459

Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; 4 BIPHENYLAMINE; AROMATIC AMINE; ARYLAMINE ACETYLTRANSFERASE;

EID: 57349197905     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.023960     Document Type: Article
Times cited : (16)

References (49)
  • 1
    • 34547661669 scopus 로고    scopus 로고
    • Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells
    • Ambrosone CB, Abrams SM, Gorlewska-Roberts K, and Kadlubar FF (2007) Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells. Arch Biochem Biophys 464:169-175.
    • (2007) Arch Biochem Biophys , vol.464 , pp. 169-175
    • Ambrosone, C.B.1    Abrams, S.M.2    Gorlewska-Roberts, K.3    Kadlubar, F.F.4
  • 3
    • 33745240359 scopus 로고    scopus 로고
    • Barker DF, Husain A, Neale JR, Martini BD, Zhang X, Doll MA, States JC, and Hein DW (2006) Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1. Pharmacogenet Genomics 16:515-525.
    • Barker DF, Husain A, Neale JR, Martini BD, Zhang X, Doll MA, States JC, and Hein DW (2006) Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1. Pharmacogenet Genomics 16:515-525.
  • 4
    • 57349163483 scopus 로고    scopus 로고
    • Barker DF, Walraven JM, Ristagno EH, Doll MA, States JC, and Hein DW (2008) Quantitative tissue and gene-specific differences and developmental changes in Nat1, Nat2, and Nat3 mRNA expression in the rat. Drug Metab Dispos 36:2435-2441.
    • Barker DF, Walraven JM, Ristagno EH, Doll MA, States JC, and Hein DW (2008) Quantitative tissue and gene-specific differences and developmental changes in Nat1, Nat2, and Nat3 mRNA expression in the rat. Drug Metab Dispos 36:2435-2441.
  • 5
    • 0024605061 scopus 로고
    • Nucleotide sequence of a full-length cDNA for arylamine N-acetyltransferase from rabbit liver
    • Blum M, Grant DM, Demierre A, and Meyer UA (1989) Nucleotide sequence of a full-length cDNA for arylamine N-acetyltransferase from rabbit liver. Nucleic Acids Res 17:3589.
    • (1989) Nucleic Acids Res , vol.17 , pp. 3589
    • Blum, M.1    Grant, D.M.2    Demierre, A.3    Meyer, U.A.4
  • 6
    • 26444618665 scopus 로고    scopus 로고
    • Arylamine N-acetyltransferases: What we learn from genes and genomes
    • Boukouvala S and Fakis G (2005) Arylamine N-acetyltransferases: what we learn from genes and genomes. Drug Metab Rev 37:511-564.
    • (2005) Drug Metab Rev , vol.37 , pp. 511-564
    • Boukouvala, S.1    Fakis, G.2
  • 7
    • 0033044237 scopus 로고    scopus 로고
    • Mutagenicity and aromatic amine content of fumes from heated cooking oils produced in Taiwan
    • Chiang TA, Pei-Fen W, Ying LS, Wang LF, and Ko YC (1999) Mutagenicity and aromatic amine content of fumes from heated cooking oils produced in Taiwan. Food Chem Toxicol 37:125-134.
    • (1999) Food Chem Toxicol , vol.37 , pp. 125-134
    • Chiang, T.A.1    Pei-Fen, W.2    Ying, L.S.3    Wang, L.F.4    Ko, Y.C.5
  • 8
    • 0027431869 scopus 로고
    • Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in tissues of C57BL/6J rapid and B6.A-NatS slow acetylator congenic mice
    • Chung JG, Levy GN, and Weber WW (1993) Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in tissues of C57BL/6J rapid and B6.A-NatS slow acetylator congenic mice. Drug Metab Dispos 21:1057-1063.
    • (1993) Drug Metab Dispos , vol.21 , pp. 1057-1063
    • Chung, J.G.1    Levy, G.N.2    Weber, W.W.3
  • 9
    • 0029098236 scopus 로고
    • Cloning, sequencing and expression of NAT1 and NAT2 encoding genes from rapid and slow acetylator inbred rats
    • Doll MA and Hein DW (1995) Cloning, sequencing and expression of NAT1 and NAT2 encoding genes from rapid and slow acetylator inbred rats. Pharmacogenetics 5:247-251.
    • (1995) Pharmacogenetics , vol.5 , pp. 247-251
    • Doll, M.A.1    Hein, D.W.2
  • 11
    • 0030725239 scopus 로고    scopus 로고
    • Higher frequency of aberrant crypt foci in rapid than slow acetylator inbred rats administered the colon carcinogen 3,2′-dimethyl-4-aminobiphenyl
    • Feng Y, Fretland AJ, Rustan TD, Jiang W, Becker WK, and Hein DW (1997) Higher frequency of aberrant crypt foci in rapid than slow acetylator inbred rats administered the colon carcinogen 3,2′-dimethyl-4-aminobiphenyl. Toxicol Appl Pharmacol 147:56-62.
    • (1997) Toxicol Appl Pharmacol , vol.147 , pp. 56-62
    • Feng, Y.1    Fretland, A.J.2    Rustan, T.D.3    Jiang, W.4    Becker, W.K.5    Hein, D.W.6
  • 12
    • 0028207404 scopus 로고
    • Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters
    • Ferguson RJ, Doll MA, Baumstark BR, and Hein DW (1994) Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters. Gene 140:247-249.
    • (1994) Gene , vol.140 , pp. 247-249
    • Ferguson, R.J.1    Doll, M.A.2    Baumstark, B.R.3    Hein, D.W.4
  • 14
    • 1842814225 scopus 로고    scopus 로고
    • Slow N-acetyltransferase 2 status leads to enhanced intrastriatal dopamine depletion in 6-hydroxydopamine-lesioned rats
    • Grundmann M, Earl CD, Sautter J, Henze C, Oertel WH, and Bandmann O (2004) Slow N-acetyltransferase 2 status leads to enhanced intrastriatal dopamine depletion in 6-hydroxydopamine-lesioned rats. Exp Neurol 187:199-202.
    • (2004) Exp Neurol , vol.187 , pp. 199-202
    • Grundmann, M.1    Earl, C.D.2    Sautter, J.3    Henze, C.4    Oertel, W.H.5    Bandmann, O.6
  • 15
    • 0015597281 scopus 로고
    • Multiple N-acetyltransferases and drug metabolism: Tissue distribution, characterization and significance of mammalian N-acetyltransferase
    • Hearse DJ and Weber WW (1973) Multiple N-acetyltransferases and drug metabolism: tissue distribution, characterization and significance of mammalian N-acetyltransferase. Biochem J 132:519-526.
    • (1973) Biochem J , vol.132 , pp. 519-526
    • Hearse, D.J.1    Weber, W.W.2
  • 16
    • 0037201542 scopus 로고    scopus 로고
    • Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis
    • Hein DW (2002) Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis. Mutat Res 506-507:65-77.
    • (2002) Mutat Res , vol.506-507 , pp. 65-77
    • Hein, D.W.1
  • 17
    • 33645117090 scopus 로고    scopus 로고
    • N-Acetyltransferase 2 genetic polymorphism: Effects of carcinogen and haplotype on urinary bladder cancer risk
    • Hein DW (2006) N-Acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk. Oncogene 25:1649-1658.
    • (2006) Oncogene , vol.25 , pp. 1649-1658
    • Hein, D.W.1
  • 18
    • 33645453469 scopus 로고    scopus 로고
    • Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster
    • Hein DW, Doll MA, Nerland DE, and Fretland AJ (2006) Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster. Mol Carcinog 45:230-238.
    • (2006) Mol Carcinog , vol.45 , pp. 230-238
    • Hein, D.W.1    Doll, M.A.2    Nerland, D.E.3    Fretland, A.J.4
  • 19
    • 0027281895 scopus 로고
    • Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
    • Hein DW, Doll MA, Rustan TD, Gray K, Feng Y, Ferguson RJ, and Grant DM (1993) Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 14:1633-1638.
    • (1993) Carcinogenesis , vol.14 , pp. 1633-1638
    • Hein, D.W.1    Doll, M.A.2    Rustan, T.D.3    Gray, K.4    Feng, Y.5    Ferguson, R.J.6    Grant, D.M.7
  • 20
    • 0028301762 scopus 로고
    • Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): Acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens
    • Hein DW, Doll MA, Rustan TD, Gray K, Ferguson RJ, and Feng Y (1994) Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens. Toxicol Appl Pharmacol 124:16-24.
    • (1994) Toxicol Appl Pharmacol , vol.124 , pp. 16-24
    • Hein, D.W.1    Doll, M.A.2    Rustan, T.D.3    Gray, K.4    Ferguson, R.J.5    Feng, Y.6
  • 21
    • 0025851043 scopus 로고
    • Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model
    • Hein DW, Rustan TD, Bucher KD, Furman EJ, and Martin WJ (1991a) Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model. J Pharmacol Exp Ther 258:232-236.
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 232-236
    • Hein, D.W.1    Rustan, T.D.2    Bucher, K.D.3    Furman, E.J.4    Martin, W.J.5
  • 22
    • 0026077162 scopus 로고
    • Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver
    • Hein DW, Rustan TD, Bucher KD, Martin WJ, and Furman EJ (1991b) Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver. Drug Metab Dispos 19:933-937.
    • (1991) Drug Metab Dispos , vol.19 , pp. 933-937
    • Hein, D.W.1    Rustan, T.D.2    Bucher, K.D.3    Martin, W.J.4    Furman, E.J.5
  • 23
    • 0026319473 scopus 로고
    • Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus
    • Hein DW, Rustan TD, Bucher KD, and Miller LS (1991c) Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus. J Pharmacol Exp Ther 259:699-704.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 699-704
    • Hein, D.W.1    Rustan, T.D.2    Bucher, K.D.3    Miller, L.S.4
  • 24
    • 0026602288 scopus 로고
    • Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus
    • Hein DW, Rustan TD, Martin WJ, Bucher KD, Miller LS, and Furman EJ (1992) Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus. Arch Toxicol 66:112-117.
    • (1992) Arch Toxicol , vol.66 , pp. 112-117
    • Hein, D.W.1    Rustan, T.D.2    Martin, W.J.3    Bucher, K.D.4    Miller, L.S.5    Furman, E.J.6
  • 25
    • 34548059291 scopus 로고    scopus 로고
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007a) Functional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements. Drug Metab Dispos 35:1649-1656.
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007a) Functional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements. Drug Metab Dispos 35:1649-1656.
  • 26
    • 34247323530 scopus 로고    scopus 로고
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007b) Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues. Drug Metab Dispos 35:721-727.
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007b) Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues. Drug Metab Dispos 35:721-727.
  • 27
    • 0033135468 scopus 로고    scopus 로고
    • Higher DNA adduct levels in urinary bladder and prostate of slow acetylator inbred rats administered 3,2′-dimethyl-4-aminobiphenyl
    • Jiang W, Feng Y, and Hein DW (1999) Higher DNA adduct levels in urinary bladder and prostate of slow acetylator inbred rats administered 3,2′-dimethyl-4-aminobiphenyl. Toxicol Appl Pharmacol 156:187-194.
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 187-194
    • Jiang, W.1    Feng, Y.2    Hein, D.W.3
  • 28
    • 0026240044 scopus 로고
    • N-Acetylation of aromatic amines: Genetic polymorphism in inbred rat strains
    • Juberg DR, Bond JT, and Weber WW (1991) N-Acetylation of aromatic amines: genetic polymorphism in inbred rat strains. Pharmacogenetics 1:50-57.
    • (1991) Pharmacogenetics , vol.1 , pp. 50-57
    • Juberg, D.R.1    Bond, J.T.2    Weber, W.W.3
  • 31
    • 0015893308 scopus 로고
    • Enzymatic N-acetylation of carcinogenic aromatic amines by liver cytosol of species displaying different organ susceptibilities
    • Lower GM Jr and Bryan GT (1973) Enzymatic N-acetylation of carcinogenic aromatic amines by liver cytosol of species displaying different organ susceptibilities. Biochem Pharmacol 22: 1581-1588.
    • (1973) Biochem Pharmacol , vol.22 , pp. 1581-1588
    • Lower Jr, G.M.1    Bryan, G.T.2
  • 32
    • 0025952469 scopus 로고
    • Molecular genetic basis of rapid and slow acetylation in mice
    • Martell KJ, Vatsis KP, and Weber WW (1991) Molecular genetic basis of rapid and slow acetylation in mice. Mol Pharmacol 40:218-227.
    • (1991) Mol Pharmacol , vol.40 , pp. 218-227
    • Martell, K.J.1    Vatsis, K.P.2    Weber, W.W.3
  • 33
    • 0027440345 scopus 로고
    • N-Acetylation polymorphism in liver and pancreas of inbred rats
    • Martell KJ and Weber WW (1993) N-Acetylation polymorphism in liver and pancreas of inbred rats. Drug Metab Dispos 21:965-966.
    • (1993) Drug Metab Dispos , vol.21 , pp. 965-966
    • Martell, K.J.1    Weber, W.W.2
  • 34
    • 0028335593 scopus 로고
    • Primary structure and molecular basis of polymorphic appearance of an acetyltransferase (AT-II)* in hamsters
    • Nagata K, Ozawa S, Miyata M, Shimada M, Yamazoe Y, and Kato R (1994) Primary structure and molecular basis of polymorphic appearance of an acetyltransferase (AT-II)* in hamsters. Pharmacogenetics 4:91-100.
    • (1994) Pharmacogenetics , vol.4 , pp. 91-100
    • Nagata, K.1    Ozawa, S.2    Miyata, M.3    Shimada, M.4    Yamazoe, Y.5    Kato, R.6
  • 35
    • 0033982771 scopus 로고    scopus 로고
    • Association between acetylator genotype and 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) DNA adduct formation in colon and prostate of inbred Fischer 344 and Wistar Kyoto rats
    • Purewal M, Fretland AJ, Schut HA, Hein DW, and Wargovich MJ (2000a) Association between acetylator genotype and 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) DNA adduct formation in colon and prostate of inbred Fischer 344 and Wistar Kyoto rats. Cancer Lett 149:53-60.
    • (2000) Cancer Lett , vol.149 , pp. 53-60
    • Purewal, M.1    Fretland, A.J.2    Schut, H.A.3    Hein, D.W.4    Wargovich, M.J.5
  • 36
    • 0034023575 scopus 로고    scopus 로고
    • 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine induces a higher number of aberrant crypt foci in Fischer 344 (rapid) than in Wistar Kyoto (slow) acetylator inbred rats
    • Purewal M, Velasco M, Fretland AJ, Hein DW, and Wargovich MJ (2000b) 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine induces a higher number of aberrant crypt foci in Fischer 344 (rapid) than in Wistar Kyoto (slow) acetylator inbred rats. Cancer Epidemiol Biomarkers Prev 9:529-532.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 529-532
    • Purewal, M.1    Velasco, M.2    Fretland, A.J.3    Hein, D.W.4    Wargovich, M.J.5
  • 38
    • 0030960852 scopus 로고    scopus 로고
    • Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice
    • Stanley LA, Mills IG, and Sim E (1997) Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice. Pharmacogenetics 7:121-130.
    • (1997) Pharmacogenetics , vol.7 , pp. 121-130
    • Stanley, L.A.1    Mills, I.G.2    Sim, E.3
  • 39
    • 33748886474 scopus 로고    scopus 로고
    • In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice
    • Sugamori KS, Brenneman D, and Grant DM (2006) In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice. Drug Metab Dispos 34:1697-1702.
    • (2006) Drug Metab Dispos , vol.34 , pp. 1697-1702
    • Sugamori, K.S.1    Brenneman, D.2    Grant, D.M.3
  • 41
    • 0037561531 scopus 로고    scopus 로고
    • Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice
    • Sugamori KS, Wong S, Gaedigk A, Yu V, Abramovici H, Rozmahel R, and Grant DM (2003) Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice. Mol Pharmacol 64:170-179.
    • (2003) Mol Pharmacol , vol.64 , pp. 170-179
    • Sugamori, K.S.1    Wong, S.2    Gaedigk, A.3    Yu, V.4    Abramovici, H.5    Rozmahel, R.6    Grant, D.M.7
  • 42
    • 0021881236 scopus 로고
    • Multipotential carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-f] quinoline in rats
    • Tanaka T, Barnes WS, Williams GM, and Weisburger JH (1985) Multipotential carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-f] quinoline in rats. Jpn J Cancer Res 76:570-576.
    • (1985) Jpn J Cancer Res , vol.76 , pp. 570-576
    • Tanaka, T.1    Barnes, W.S.2    Williams, G.M.3    Weisburger, J.H.4
  • 44
    • 38049138816 scopus 로고    scopus 로고
    • Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: A potential marker for the developing neuroendocrine system
    • Wakefield L, Cornish V, Long H, Kawamura A, Zhang X, Hein DW, and Sim E (2008) Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system. Biomarkers 13:106-118.
    • (2008) Biomarkers , vol.13 , pp. 106-118
    • Wakefield, L.1    Cornish, V.2    Long, H.3    Kawamura, A.4    Zhang, X.5    Hein, D.W.6    Sim, E.7
  • 45
    • 38449091987 scopus 로고    scopus 로고
    • Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and functional characterization of a novel rNat3*2 genetic variant
    • Walraven JM, Barker DF, Doll MA, and Hein DW (2007) Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and functional characterization of a novel rNat3*2 genetic variant. Toxicol Sci 99:413-421.
    • (2007) Toxicol Sci , vol.99 , pp. 413-421
    • Walraven, J.M.1    Barker, D.F.2    Doll, M.A.3    Hein, D.W.4
  • 46
    • 33749010107 scopus 로고    scopus 로고
    • Identification and characterization of functional rat arylamine N-acetyltransferase 3: Comparisons with rat arylamine N-acetyltransferases 1 and 2
    • Walraven JM, Doll MA, and Hein DW (2006) Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2. J Pharmacol Exp Ther 319:369-375.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 369-375
    • Walraven, J.M.1    Doll, M.A.2    Hein, D.W.3
  • 47
    • 0028873899 scopus 로고
    • Comparison of acetyl coenzyme A:arylamine N-acetyltransferase activity in the liver, kidney, and intestine of male and female rats from three strains
    • Ware JA, Divakaruni P, and Svensson CK (1995) Comparison of acetyl coenzyme A:arylamine N-acetyltransferase activity in the liver, kidney, and intestine of male and female rats from three strains. Drug Metab Dispos 23:295-297.
    • (1995) Drug Metab Dispos , vol.23 , pp. 295-297
    • Ware, J.A.1    Divakaruni, P.2    Svensson, C.K.3
  • 48
    • 0030598397 scopus 로고    scopus 로고
    • Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat: Evidence for multiplicity of N-acetyltransferases in the intestine
    • Ware JA and Svensson CK (1996) Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat: evidence for multiplicity of N-acetyltransferases in the intestine. Biochem Pharmacol 52:1613-1620.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1613-1620
    • Ware, J.A.1    Svensson, C.K.2
  • 49
    • 29244478873 scopus 로고    scopus 로고
    • 4,4′-Methylenedianiline-induced hepatotoxicity is modified by N-acetyltransferase 2 (NAT2) acetylator polymorphism in the rat
    • Zhang X, Lambert JC, Doll MA, Walraven JM, Arteel GE, and Hein DW (2006) 4,4′-Methylenedianiline-induced hepatotoxicity is modified by N-acetyltransferase 2 (NAT2) acetylator polymorphism in the rat. J Pharmacol Exp Ther 316:289-294.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 289-294
    • Zhang, X.1    Lambert, J.C.2    Doll, M.A.3    Walraven, J.M.4    Arteel, G.E.5    Hein, D.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.