Post-Transcriptional and Epigenetic Regulation of Antigen Processing Machinery (APM) Components and HLA-I in Cervical Cancers from Uighur Women

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Hasim, Ayshamgul ^a   Abudula, Mangnishahan ^a   Aimiduo, Reshalaiti ^a   Ma, Jun Qi ^a   Jiao, Zhen ^b   Akula, Gulzareye ^a   Wang, Ting ^a   Abudula, Abulizi ^a  

^a Medical University of Xinjiang   (China)

^b Department of Gynecology in the Hospital of Xinjiang Uighur Autonomous Region ^*  (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN PROCESSING MACHINERY PROTEIN; BISULFITE; CALNEXIN; CALRETICULIN; CARRIER PROTEIN; CELL PROTEIN; ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1; HLA ANTIGEN CLASS 1; LOW MOLECULAR MASS PROTEIN 2; LOW MOLECULAR MASS PROTEIN 7; PROTEIN P57; REGULATOR PROTEIN; TAPASIN; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; CPG ISLAND; DNA MODIFICATION; EPIGENETICS; ETHNIC GROUP; FEMALE; HLA A GENE; HLA B GENE; HLA C GENE; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN TISSUE; MAJOR CLINICAL STUDY; METHYLATION; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; UIGHUR; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU;

ADULT; AGED; ANTIGEN PRESENTATION; ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CHINA; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MIDDLE AGED; NEOPLASM STAGING; PAPILLOMAVIRUS INFECTIONS; PROMOTER REGIONS, GENETIC; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; UTERINE CERVICAL NEOPLASMS;

HUMAN PAPILLOMAVIRUS - 16; HUMAN PAPILLOMAVIRUS TYPE 16;

EID: 84866375600     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044952     Document Type: Article

References (40)

1. Burd EM, (2003) Human Papillomavirus and cervical caner. Clin Microbiol Rev16 (1): 1-7.
2. Marincola FM, JaVee EM, Hicklin DJ, Ferrone S, (2000) Escape of human solid tumors from T cell recognition: molecular mechanisms and functional significance. Adv Immunol 74: 181-273.
3. Knutson KL, Disis ML, (2005) Tumor antigen-specific T helper cells in cancer immunity and immunotherapy. Cancer Immunol Immunother 54: 721-728.
4. Moretta L, Bottino C, Pende D, Vitale M, Mingari MC, et al. (2005) Human natural killer cells: molecular mechanisms controlling NK cell activation and tumor cell lysis. Immunol Lett. 100: 7-13.
5. Liu Q, Hao C, Su P, Shi J, (2009) Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: association with disease progression. Scand J Gastroenterol (448) ():: 960-969.
6. Ayshamgul H, Ma H, Ilyar S, Zhang LW, Abulizi A, (2011) Association of defective HLA-I expression with antigen processing machinery and their association with clinicopathological characteristics in Kazak patients with esophageal cancer. Chin Med J (Engl) (1243) ():: 341-346.
7. Hasim A, Qing S, Wu XC, Ge L, Abudula A, (2010) Association of expression of antigen processing machinery components with HLA-I in cervical lesions. Chin J Pathol 39(10): 703-704.
8. Cathro HP, Smolkin ME, Theodorescu D, Jo VY, Ferrone S, et al. (2010) Relationship between HLA class I antigen processing machinery component expression and the clinico- pathologic characteristics of bladder carcinomas[J]. Cancer Immunol Immunother 59: 465-472.
9. Seliger B, Ritz U, Ferrone S, (2006) Molecular mechanisms of HLA class I antigen abnormalities following viral infection and transformation. Int J Cancer 118: 129-138.
10. Nie Y, Yang G, Song Y, Zhao X, So C, et al. (2001) DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas. Carcinogen 22: 1615-1623.
11. Sigalotti L, Fratta E, Coral S, Tanzarella S, Danielli R, et al. (2004) Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by5-aza-2′-deoxycytidine. Cancer Res 64: 9167-9171.
12. International Agency on Research on Cancer (IARC) (1995) Monograph on cancer, Human papillomavirus. Vol: 64. World Health Organization.
13. Castellsague X, Muñoz N, (2003) Cofactors in human papillomavirus carcinogenesis-role of parity, oral contraceptives, and tobacco smoking. J Natl Cancer Inst Monogr 31: 20-28.
14. Yang B, Bray F, Parkin D, Sellors J, Zhang Z (2004)Cervical cancer as a priority for prevention in different world regions: an evaluation using years of life lost. Int. J. Cancer 109(3), 418-424.
15. Lalai Suzuk,Yu-Hua Peng Fu-sheng Zhou (2006) Analysis of the cervical cancer distribution in Xinjiang. Journal of Xinjiang Medical University 29(7), 569-571. (Article in Chinese).
16. Hasimu A, Sheng L, Ma Q, Ma JQ, Aubdula A, (2011) Differential expression of human leukocyte antigen I between patients of Uighur and Han ethnic groups with cervical diseases. Tumor 31(5): 432-435.
17. Ma Q, Hasimu A, Abudukadeer A, Yilike X, Wu GZ, et al. (2010) Correlation between human papillomavirus type 16 infection and human leukocyte antigen class I expression in cervical cancers of Uighur women. Chin J Pathol 39(4): 255-258.
18. Hasim A, Qing S, Wu XC, Ge L, Abudula A, (2010) Association of expression of antigen processing machinery components with HLA-I in cervical lesions. Chin J Pathol 39(10): 703-704.
19. Stam NJ, Vroom TM, Peters PJ, Pastoors EB, Ploegh HL, (1990) HLA-A- and HLA-B-specific antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immunoelectron microscopy. Int. Immunol. 2(2): 113-125.
20. Akash M, Mehta Ekaterina S, Jordanova GG, Kenter SF, Gert-Jan F, (2008) Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma. Cancer Immunol Immunother 57(2): 197-206.
21. Herman JG, Graff JR, Myohanen S, Nelkin B, Baylin SB, (1996) Methylation-specific PCR. A novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA93(18): 9821-9826.
22. Li W, Fang W, Jing G, Jing L, Lihua W, et al. (2010) Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects. Am J Clin Nutr 91(5): 1359-1367.
23. Olk-Batz C, Poetsch AR, Nöllke P, Claus R, Zucknick M, et al. (2011) Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome. Blood 117(18): 4871-4880.
24. Corneanu LM, Stǎnculescu D, Corneanu C, (2011) HPV and cervical squamous intraepithelial lesions: clinicopathological study. Rom J Morphol Embryol 52(1): 89-94.
25. Sanchez CJ, Le Treut T, Boehrer A, Knoblauch B, Imbert D, et al. (2011) Natural killer cells and malignant haemopathies: a model for the interaction of cancer with innate immunity. Cancer Immunol Immunother 60: 1-13.
26. Qiao L, Chun-yan H, Peng S, (2009) Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: Association with disease progression. Scandinavian Journal of Gastroenterology 44: 960-969.
27. Lee HW, Min SK, Ju YS, Sung J, Lim MS, et al. (2011) Prognostic Significance of HLA Class I Expressing in Gastric Carcinoma Defined by Monoclonal Anti-Pan HLA Class I Antibody, EMR8-5. J Gastrointest Surg 15(8): 1336-1343.
28. Tanaka K, Tsuchikawa T, Miyamoto M, Maki T, Ichinokawa M, et al. (2011) Down-regulation of Human Leukocyte Antigen class I heavy chain in tumors is associated with a poor prognosis in advanced esophageal cancer patients.Int J Oncol 1274.
29. Seliger B, Maeurer MJ, Ferrone S, (2000) Antigen processing machinery breakdown and tumor growth. Immunol Today 21: 455-464.
30. Watson NF, Ramage JM, Madjd Z, Spendlove I, Ellis IO, et al. (2006) Immunosurveillance is active in colorectal cancer as downregulation but not complete loss of MHC class I expression correlates with a poor prognosis. Int J Cancer118: 6-10.
31. Lou Y, Basha G, Seipp RP, Cai B, Chen SS, et al. (2008) Combining the antigen processing components TAP and Tapasin elicits enhanced tumor-free survival. Clin Cancer Res 14:/1494-1501.
32. Ayshamgul H, Qiao-zhi L, Abulizi A, (2010) expression of HLA-I antigen, CD3 and CD8 in cervical lesions and their clinical significance in Uighur women. JClin Exp Pathol 26(6): 684-687 (Article in Chinese).
33. Khan AN, Gregorie CJ, Tomasi TB, (2008) Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells. Cancer Immunol Immunother 57: 647-654.
34. Tomasi TB, Magner WJ, Khan AN, (2006) Epigenetic regulation of immune escape genes in cancer. Cancer Immunol Immunother 10: 1159-1184.
35. Manning J, Indrova M, Lubyova B, Pribylova H, Bieblova J,et al. (2008) Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. Immunology123, 218-227.
36. Nie XR, Zhang Y, Pan KF, Zhang L, Zhou T, et al. (2009) association between promoter methylation of cyclooxygenase-2 and expression and precancerous gastric lesions in a high-risk population.chin J Prev,Med. 43(7): 571-575.
37. Rincon-Orozco B, Halec G, Rosenberger S, Muschik D, Nindl I, et al. (2009). Epigenetic Silencing of Interferon-κ in Human Papillomavirus Type 16-Positive Cells. Cancer Res 69: (22) 15, 8718-8725.
38. Adhya D, Basu A, (2010) Epigenetic modulation of host: new insights into immune evasion by viruses J. Biosci. 35(4): 647-663.
39. Kuzmin I, Liu L, Dammann R, Geil L, Stanbridge EJ, et al. (2003) Inactivation of RAS Association Domain Family 1A Gene in Cervical Carcinomas and the Role of Human Papillomavirus Infection. Cancer Res 63(8): 1888-1893.
40. Seliger B, Ritz U, Ferrone S, (2006) Molecular mechanisms of HLA class I antigen abnormalities following viral infection and transformation. Int J Cancer 118(1): 129-138.