Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1824, Issue 1, 2012, Pages 3-13

  Ciechanover, Aaron ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Diseases; Lysosome; Proteasome; Proteolysis; Ubiquitin

Indexed keywords

ADENOSINE TRIPHOSPHATE; BOVINE SERUM ALBUMIN; CARRIER PROTEIN; CATHEPSIN B; CELL PROTEIN; GLOBIN; LYSOSOME ENZYME; MEMBRANE PROTEIN; PROTEASOME; SUMO PROTEIN; TRANSCRIPTION FACTOR; TRITIUM; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME;

AUTOPHAGY; CELL CYCLE; CELL DIVISION; CELL ORGANELLE; CELL VACUOLE; DEGENERATIVE DISEASE; DRUG TARGETING; ENDOCYTOSIS; HUMAN; LYSOSOME; NEOPLASM; NEUROLOGIC DISEASE; NONHUMAN; NUCLEAR PORE COMPLEX; PHAGOCYTOSIS; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; TRANSCRIPTION REGULATION;

ANIMALS; DISEASE; DRUG DELIVERY SYSTEMS; HUMANS; INTRACELLULAR SPACE; LYSOSOMES; MODELS, BIOLOGICAL; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SIGNAL TRANSDUCTION; UBIQUITIN;

EID: 82755187338     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.03.007     Document Type: Review

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