Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features

Gastroenterology

Volumn 116, Issue 6, 1999, Pages 1348-1357

  Yamamoto, H ^a   Perez Piteira, J ^a   Yoshida, T ^a   Terada, M ^a   Itoh, F ^a   Imai, K ^a   Perucho, M ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; PROTEIN P53;

ARTICLE; CANCER GENETICS; CELL DIFFERENTIATION; COLON CANCER; GENOTYPE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; SOMATIC MUTATION; STOMACH CANCER;

EID: 0033038815     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70499-3     Document Type: Article

References (52)

1. Y Ionov MA Peinado S Malkhosyan D Shibata M. Perucho Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Nature 363 1993 558 561
2. SN Thibodeau G Bren D. Schaid Microsatellite instability in cancer of the proximal colon Science 260 1993 816 819
3. LA Aaltonen P Peltomaki FS Leach P Sistonen L Pylkkanen JP Mecklin H Javinen SM Powell J Jen SR Hamilton GM Petersen KW Kinzler B Vogelstein A. Chapelle Clues to the pathogenesis of familial colorectal cancer Science 260 1993 812 816
4. G Marra CR. Boland Hereditary nonpolyposis colorectal cancer (HNPCC): the syndrome, the genes, and historical perspectives J Natl Cancer Inst 87 1995 1114 1125
5. R. Kolodner Mismatch repair: mechanisms and relationship to cancer susceptibility Trends Biochem Sci 20 1995 397 401
6. KW Kinzler B. Vogelstein Lessons from hereditary colorectal cancer Cell 87 1996 159 170
7. M. Perucho Cancer of the microsatellite mutator phenotype Biol Chem 377 1996 675 684
8. N Arnheim D. Shibata DNA mismatch repair in mammals: role in disease and meiosis Curr Opin Genet Dev 7 1997 364 370
9. H Kim J Jen B Vogelstein SR. Hamilton Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite instability Am J Pathol 145 1994 148 156
10. M Konishi R Kikuchi-Yanoshita K Tanaka M Muraoka A Onda Y Okumura N Kishi T Iwama T Mori M Koike K Ushio S Nomizu F Konishi J Utsunomiya M. Miyaki Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer Gastroenterology 111 1996 307 317
11. S Olschwang R Hamelin P Laurent-Puig B Thuille YD Rycke YJ Li F Muzeau J Girodet R-J Salmon G. Thomas Alternative genetic pathways in colorectal carcinogenesis Proc Natl Acad Sci USA 94 1997 12122 12127
12. + status and p53 mutation in colorectal cancer cell lines Oncogene 13 1996 2727 2730
13. M Perucho MA Peinado Y Ionov S Casares S Malkhosyan E. Stanbridge Defects in replication fidelity of simple repeated sequences reveal a new mutator mechanism for oncogenesis Cold Spring Harbor Symp 59 1994 339 348
14. ER Fearon B. Vogelstein A genetic model for colorectal tumorigenesis Cell 61 1991 759 767
15. B Liu NC Nicolaides S Markowitz JKV Willson R Parsons J Jen N Papadopolous P Peltomaki A de la Chapelle SR Hamilton KW Kinzler B. Vogelstein Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability Nat Genet 9 1995 48 55
16. V Lazar S Grandjouan C Bognel D Couturier P Rougier D Bellet B. Bressac-de Paillerets Accumulation of multiple mutations in tumor suppressor genes during colorectal tumorigenesis in HNPCC patients Hum Mol Genet 3 1994 2257 2260
17. M. Perucho Letter to the Editor Cancer Res 59 1998 249 253 58:5248-5257 and 1999
18. JL Weber C. Wong Mutation of human short tandem repeats Hum Mol Genet 2 1993 1123 1128
19. L Zhang EP Leeflang J Yu N. Arnheim Studying human mutations by sperm typing: instability of CAG trinucleotide repeats in the human androgen receptor gene Nat Genet 7 1994 531 535
20. R Wooster A-M Cleton-Jansen N Collins J Mangion RS Cornelis CS Cooper BA Gusterson BAJ Ponder A von Deimling OD Wiestler CJ Cornelisse P Devilee MR. Stratton Instability of short tandem repeats (microsatellites) in human cancers Nat Genet 6 1994 152 156
21. L Mao DJ Lee MS Tockman YS Erozan F Askin D. Sidransky Microsatellite alterations as clonal markers for the detection of human cancer Proc Natl Acad Sci USA 91 1994 9871 9875
22. H Yamamoto H Sawai TK Weber MA Rodriguez-Bigas M. Perucho Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer Cancer Res 58 1998 997 1003
23. HT Lynch TC Smyrk P Watson SJ Lanspa JF Lynch PM Lynch RJ Cavalieri CR. Boland Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an update review Gastroenterology 104 1993 1535 1549
24. HJ Han A Yanagisawa Y Kato J-G Park Y. Nakamura Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer Cancer Res 53 1993 5087 5089
25. H Yamamoto H Sawai M. Perucho Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator pheno-type Cancer Res 57 1997 4420 4426
26. CR Boland SN Thibodeau SR Hamilton D Sidransky JR Eshleman RW Burt SJ Meltzer MA Rodriguez-Bigas R Fodde N Ranzani S. Srivastava A National Cancer Institute workshop on microsatel-lite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer Cancer Res 58 1998 5248 5257
27. JM Hoang PH Cuttu B Thuille RJ Salmon G Thomas R. Hamelin BAT-26, an indicator of the replication error phenotype in colorectal cancer and cell lines Cancer Res 57 1997 300 303
28. SD Markowitz J Wang L Myeroff R Parsons L Sun J Lutterbaugh RS Fan E Zborowska KW Kinzler B Vogelstein M Brattain JKV. Wilson Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability Science 268 1995 1336 1338
29. S Malkhosyan N Rampino H Yamamoto M. Perucho Frameshift mutator mutations Nature 382 1996 499 500
30. N Rampino H Yamamoto Y Ionov Y Li H Sawai JC Reed M. Perucho Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype Science 275 1997 967 969
31. MF Kane M Loda GM Gaida J Lipman R Mishra H Goldman JM Jessup R. Kolodner Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines Cancer Res 57 1997 808 811
32. JG Herman A Umar K Polyak JR Graff N Ahuja JPJ Issa S Markowitz JKV Willson SR Hamilton WK Kinzler MF Kane RD Kolodner B Vogelstein TA Kunkel SB. Baylin Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma Proc Natl Acad Sci USA 95 1998 6870 6875
33. W Bodmer T Bishop P. Karran Genetic steps in colorectal cancer Nat Genet 6 1994 217 219
34. DC Bicknell L Kaklamanis R Hampson WF Bodmer P Karran Selection for β2-microglobulin mutation in mismatch repair-defective colorectal carcinomas Curr Biol 6 1996 1695 1697
35. MS Kahlenberg DL Stoler NJ Petrelli M Rodriguez-Bigas GR Anderson p53 tumor suppressor gene status and the degree of genomic instability in sporadic colorectal cancers J Natl Cancer Inst 88 1996 1665 1670
36. TK Weber W Conlon NJ Petrelli M Rodriguez-Bigas B Keitz J Pazik C Farrell L O'Malley M Oshalim M Abdo G Anderson D Stoler D. Yandell Genomic DNA-based hMSH2 and hMLH1 mutation screening in 32 eastern United States hereditary nonpolyposis colorectal cancer pedigrees Cancer Res 57 1997 3798 3803
37. A Hemminki P Peltomaki JP Mecklin H Jarvinen R Salovaara M Nystrom-Lahti A de la Chapelle LA Aaltonen Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer Nat Genet 8 1994 405 410
38. SN Thibodeau AJ French JM Cunningham D Tester LJ Burgart PC Roche SK McDonnell DJ Schaid WV Vockley VV Michels GH Farr Jr MJ. O'Connell Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1 Cancer Res 58 1998 1713 1718
39. JG Stricker J Zheng Q Shu LJ Burgart SR Alberts D Shibata p53 mutations and microsatellite instability in sporadic gastric cancer: when gurdians fail Cancer Res 54 1994 4750 4755
40. B Renault D Calistri G Buonsanti O Nanni D Amadori GN Ranzani Microsatellite instability and mutations of p53 and TGF-β RII genes in gastric cancer Hum Genet 98 1996 601 607
41. MS Greenblatt WP Bennett M Hollstein CC Harris Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis Cancer Res 54 1994 4855 4878
42. N Papadopoulos NC Nicolaides B Liu R Parsons C Lengauer F Palombo A D'Arrigo S Markowitz JKV Willson KW Kinzler J Jiricny B. Vogelstein Mutations of GTBP in genetically unstable cells Science 268 1995 1915 1917
43. 2-microglobulin mRNA in human DAUDI cells has a mutated initiation codon but is still induced by interferon EMBO J 2 1983 239 243
44. SN Thibodeau AJ French PC Roche JM Cunningham DJ Tester NM Lindor G Moslein SM Bakerm RM Liskay LJ Burgart R Honchel KC. Halling Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes Cancer Res 56 1996 4836 4840
45. S Casares Y Ionov HY Ge E Stanbridge M. Perucho The microsatellite mutator phenotype of colon cancer cells is often recessive Oncogene 11 1995 2303 2310
46. J Wijnen H van der Klift H Vasen PM Khan F Menko C Tops HM Heijboer D Lindhout P Moller R. Fodde MSH2 genomic deletions are a frequent cause of HNPCC Nat Genet 20 1998 326 328
47. M. Perucho Microsatellite instability: the mutator that mutates the other mutator Nat Med 2 1996 630 631
48. Y Akiyama H Sato T Yamada H Nagasaki A Tsuchiya R Abe Y. Yuasa Germiline mutation of the hMSH6/GTBP in an atypical hereditary nonpolyposis colorectal cancer kindred Cancer Res 57 1997 3920 3923
49. M Miyaki M Konishi K Tanaka R Kikuchi-Yanoshita M Muraoka M Yasuno T Igari M Koike M Chiba T. Mori Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer Nat Genet 17 1997 271 272
50. R Seruca NR dos Santos L David M Constancia H Barroca F Carneiro M Seixas P Peltomaki R Lothe M. Sobrinho-Simoes Sporadic gastric carcinoma with microsatellite instability display a particular clinicopathologic profile Int J Cancer 64 1995 32 36
51. NR dos Santos R Seruca M Constancia M Seixas M. Sorbinho-Simoes Microsatellite instability at multiple loci in gastric carcinoma: clinicopathologic implications and prognosis Gastroenterology 110 1996 38 44
52. Y-J Chung J-M Song J-Y Lee Y-T Jung E-J Seo S-W Choi M-G. Rhyu Microsatellite instability-associated mutations associate preferentially with the intestinal type of primary gastric carcinomas in a high-risk population Cancer Res 56 1996 4662 4665