HLA class 1 expression and chromosomal deletions at 6p and 15q in head and neck squamous cell carcinomas

Tissue Antigens

Volumn 54, Issue 3, 1999, Pages 235-245

  Feenstra, M ^a   Veltkamp, M ^a   Van Kuik, J ^a   Wiertsema, S ^a   Slootweg, P ^a   Van den Tweel, J ^a   De Weger, R ^a   Tilanus, M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

2m; Expression; HLA; HNSCC; LOH; Microsatellites; STRs

Indexed keywords

BETA 2 MICROGLOBULIN; HLA ANTIGEN CLASS 1; ABC TRANSPORTER; DNA; HLA A ANTIGEN; HLA ANTIGEN; MICROSATELLITE DNA; TAP1 PROTEIN, HUMAN; TAP2 PROTEIN, HUMAN;

ANTIGEN EXPRESSION; ARTICLE; CHROMOSOME 15Q; CHROMOSOME 6P; CHROMOSOME DELETION; HEAD AND NECK CARCINOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; BIOSYNTHESIS; CHEMISTRY; CHROMOSOME 15; CHROMOSOME 6; CHROMOSOME MAP; CYTOPLASM; GENETICS; HEAD AND NECK TUMOR; LYMPH NODE; MAJOR HISTOCOMPATIBILITY COMPLEX; TRINUCLEOTIDE REPEAT;

ATP-BINDING CASSETTE TRANSPORTERS; BETA 2-MICROGLOBULIN; CARCINOMA, SQUAMOUS CELL; CHROMOSOME DELETION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 6; CYTOPLASM; DNA, NEOPLASM; HEAD AND NECK NEOPLASMS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HLA-A ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; LYMPH NODES; LYMPHATIC METASTASIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROSATELLITE REPEATS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 0032586280     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0039.1999.540304.x     Document Type: Article

References (32)

1. Weber J, May P. Abundant class of human DNA polymorphisms which can be typed using polymerase chain reaction. Am J Hum Genet 1989: 44: 388-96.
2. Dip C, Fauré S, Fizames C et al. A comprehensive genetic map of the human genome based on 5264 microsatellites. Nature 1996: 380: 152-4.
3. Bruford M, Wayne R. Microsatellites and their application to population genetic studies. Curr Opin Genet Dev 1993: 3: 939-43.
4. Hearne C, Gosh S, Todd J. Microsatellites for linkage analysis of genetic traits. Trends Genet 1992: 8: 288-94.
5. Marshall CJ. Tumor suppressor genes. Cell 1991: 64: 313-18.
6. Fossaic A, Crounau-Roy B, Fauré S, Thomsen M, Cambon Thomsen A. An update on microsatellites in the HLA region. Tissue Antigens 1998: 52: 318-52.
7. Tamiya G, Ota M, Katsuyama Y et al. Twenty-six new polymorphic microsatellite markers around the HLA-B, -C and -E loci in the human class I region. Tissue Antigens 1998: 51: 337-46.
8. Campbell RD, Trowsdale J. Map of the human major histocompatibility complex. Immunol Today 1993: 14: 349-52.
9. Maffei A, Papadopoulos K, Harris PE. MHC class I antigen processing pathways. Hum Immunol 1997: 54: 91-103.
10. Townsend A, Bodmer H. Antigen recognition by class I restricted T lymphocytes. Annu Rev Immunol 1989: 7: 601-5.
11. Garrido F, Cabrera T, Lopez-Nevot MA, Ruiz-Cabello F. HLA Class I antigens in human tumors. Adv Cancer Res 1995: 67: 155-93.
12. Garrido F, Ruiz-Cabello F, Cabrera T et al. Implications for immunosurveillance of altered HLA class I phenotypes in human tumors. Immunol Today 1997: 18: 89-95.
13. Ferrone S, Marincola FM. Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. Immunol Today 1995: 16: 487-94.
14. Feenstra M, Duran K, Stuy I et al. Mutation in the β2m gene is not a frequent event in head and neck squamous cell carcinomas with aberrant HLA class I expression. Hum Immunol: in press.
15. D'Urso C, Wang Z, Cao Y, Tatake R, Zeff RA, Ferrone S. Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in β2-microglobulin gene expression. J Clin Invest 1990: 87: 284-92.
16. Goodfellow PN, Jones EA, Van Heyningen V et al. The β2-microglobulin gene is on chromosome 15 and not in the HLA region. Nature 1989: 254: 267-8.
17. Shanmugaratnam K, Sobin LH. Histological typing of tumours of the upper respiratory tract and ear. 2nd edn. New-York: Springer-Verlag, 1991.
18. Stam NJ, Vroom ThM, Peters PJ, Pastoors EB, Ploegh HL. HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in Western blot, in paraffin-embedded tissue sections and in cryo-immuno-electronmicroscopy. Int Immunol 1990: 2: 113-25.
19. Kleijmeer MJ, Kelly A, Geuze HJ, Slot JW, Townsend A, Trowsdale J. Location of MHC-encoded transporters in the endoplasmatic reticulum and cis-Golgi. Nature 1992: 357: 342-4.
20. Miller SA, Dykes DD, Polesky HFA. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988: 16: 1215.
21. Gyapay G, Morissette J, Vignal A et al. The 1993-94 Généthon human genetic linkage map. Nat Genet 1994: 7: 246-9.
22. Fossaic A, Crounau-Roy B, Fauré S, Thomsen M, Cambon Thomsen A. Microsatellites in the HLA region: an overview. Tissue Antigens 1997: 49: 197-214.
23. Malcolm S, Donlon TA. Report of the second international workshop on human chromosome 15 mapping 1994. Cytogenet Cell Genet 1994: 67: 2-22.
24. Dutrillaux B. Pathways of chromosome alteration in human epithelial cancers. Adv Cancer Res 1995: 67: 59-82.
25. Boon T, van der Bruggen P. Human tumor antigens recognized by T lymphocytes. J Exp Med 1994: 183: 725-9.
26. Foulkes WD, Ragoussis J, Stamp GWH, Allan GJ, Trowsdale J. Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma. Br J Cancer 1993: 67: 551-9.
27. Torres MJ, Ruiz-Cabello F, Skoudy A et al. Loss of an HLA haplotype in pancreas cancer tissue and its corresponding tumor derived cell line. Tissue Antigens 1996: 47: 372-81.
28. Randerson J, Cakwell L, Jack A et al. Fluorescent polymerase chain reaction of a panel of CA repeats on chromosome 6 in the indolent phase of follicular centre cell lymphoma. Br J Cancer 1996: 74: 942-6.
29. Real LM, Jimenez P, Canton J et al. In vivo and in vitro generation of a new altered HLA phenotype in melanoma-tumour-cell variants expressing a single HLA-class-I allele. Int J Cancer 1998: 75: 317-23.
30. Tripodis N, Mason R, Humphray SJ et al. Physical map of human 6p21.2-6p21.3: Region flanking the centromeric end of the major histocompatibility complex. Genome Research 1998: 8: 631-43.
31. Herberg JA, Sgouros J, Jones T et al. Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC. Eur J Immunol 1998: 28: 459-67.
32. Hiraga S, Ohnishi T, Izumoto S, Miyahara E, Kanemura Y, Matsumura H, Arita N. Telomerase activity and alterations in telomere length in human brain tumors. Cancer Res 1998: 58: 2117-25.