Alternative dietary fiber sources in companion animal nutrition

Nutrients

Volumn 5, Issue 8, 2013, Pages 3099-3117

  de Godoy, Maria R C ^a   Kerr, Katherine R ^a   Fahey Jr , George C ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Beet pulp; Cellulose; Companion animal; Corn fiber; Fruit fiber; Rice bran; Whole grains

Indexed keywords

BETA GLUCAN; MICROCRYSTALLINE CELLULOSE; TAURINE;

ANIMAL FOOD; BEETLE PUP; BRAN; CARBOHYDRATE INTAKE; CEREAL; CHEMICAL COMPOSITION; CORN FIBER; DIETARY FIBER; DIETARY INTAKE; FOOD INDUSTRY; FRUIT; FRUIT FIBER; GRAIN; HEART PROTECTION; INSULIN RESPONSE; MACRONUTRIENT; NONHUMAN; NUTRITIONAL ASSESSMENT; NUTRITIONAL STATUS; NUTRITIONAL VALUE; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; REVIEW; RICE; SOLUBILITY; UNITED STATES; WATER CONTENT;

ANIMALIA; BETA VULGARIS SUBSP. VULGARIS; CANIS FAMILIARIS; FELIDAE; HORDEUM; ZEA MAYS;

EID: 84881500956     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu5083099     Document Type: Review

References (86)

1. American Veterinary Medical Association. US Pet Ownership & Demographics Sourcebook (2012); American Veterinary Medical Association: Schaumburg, IL, USA, 2012.
2. Institute of Medicine of the National Academies. Dietary Reference Intakes; The National Academies Press: Washington, DC, USA, 2002.
3. Jenkins, A.L.; Jenkins, D.J.; Wolever, T.M.; Rogovik, A.L.; Jovanovski, E.; Bozikov, V.; Rahelic, D.; Vuksan, V. Comparable postprandial glucose reductions with viscous fiber blend enriched biscuits in healthy subjects and patients with diabetes mellitus: Acute randomized controlled clinical trial. Croat. Med. J. 2008, 49, 772-782.
4. Brennan, C.S.; Cleary. L.J. The potential role of cereal (1.3,1.4)-beta-D-glucans as functional food ingredients. J. Cereal Sci. 2005, 42, 1-13.
5. Tungland, B.C. Fructooligosaccharides and other fructans: Structures and occurence, production, regulatory aspects, food applications and nutritional health significance. ACS Symp. Ser. 2003, 849, 135-152.
6. German, J.B.; Xu, R.; Walzem, R.; Kinsella, J.E.; Knuckles, B.; Nakamura, M.; Yokoyama, W.H. Effect of dietary fats and barley fiber on total cholesterol and lipoprotein cholesterol distribution in plasma of hamsters. Nutr. Res. 1996, 16, 1239-1249.
7. Wenk, C. The role of dietary fibre in the digestive physiology of the pig. Anim. Feed Sci. Technol. 2001, 90, 21-33.
8. Sunvold, G.D.; Fahey, G.C., Jr.; Merchen, N.R.; Bourquin, L.D.; Titgemeyer, E.C.; Bauer, L.L.; Reinhart, G.A. Dietary fiber for cats: In vitro fermentation of selected fiber sources by cat fecal inoculum and in vivo utilization of diets containing selected fiber sources and their blends. J. Anim. Sci. 1995, 73, 2329-2339.
9. Sunvold, G.D.; Fahey, G.C., Jr.; Merchen, N.R.; Titgemeyer, E.C.; Bourquin, L.D.; Bauer, L.L.; Reinhart, G.A. Dietary fiber for dogs: IV. In vitro fermentation of selected fiber sources by dog fecal inoculum and in vivo digestion and metabolism of fiber-supplemented diets. J. Anim. Sci. 1995, 73, 1099-1109.
10. Sunvold, G.D.; Fahey, G.C., Jr.; Merchen, N.R.; Reinhart, G.A. In vitro fermentation of selected fibrous substrates by dog and cat fecal inoculum: Influence of diet composition on substrate organic matter disappearance and short-chain fatty acid production. J. Anim. Sci. 1995, 73, 1110-1122.
11. Fahey, G.C., Jr.; Merchen, N.R.; Corbin, J.E.; Hamilton, A.K.; Serbe, K.A.; Lewis, S.M.; Hirakawa, D.A. Dietary fiber for dogs: I. Effects of graded levels of dietary beet pulp on nutrient intake, digestibility, metabolizable energy and digesta mean retention time. J. Anim. Sci. 1990, 68, 4221-4228.
12. Sunvold, G.D.; Hussein, H.S.; Fahey, G.C., Jr.; Merchen, N.R.; Reinhart, G.A. In vitro fermentation of cellulose, beet pulp, citrus pulp, and citrus pectin using fecal inoculum from cats, dogs, horses, humans, and pigs and ruminal fluid from cattle. J. Anim. Sci. 1995, 73, 3639-3648.
13. Bosch, G.; Pellikaan, W.F.; Rutten, P.G.P.; van der Poel, A.F.B.; Verstegen, M.W.A.; Hendriks, W.H. Comparative in vitro fermentation activity in the canine distal gastrointestinal tract and fermentation kinetics of fiber sources. J. Anim. Sci. 2008, 86, 2979-2989.
14. Fischer, M.M.; Kessler, A.M.; de Sá, L.R.M.; Vasconcellos, R.S.; Roberti Filho, F.O.; Nogueira, S.P.; Oliveira, M.C.C.; Carciofi, A.C. Fiber fermentability effects on energy and macronutrient digestibility, fecal traits, postprandial metabolite responses, and colon histology of overweight cats. J. Anim. Sci. 2012, 90, 2233-2245.
15. Fekete, S.G.; Hullár, I.; Andrásofszky, E.; Kelemen, F. Effect of different fiber types on the digestibility of nutrients in cats. J. Anim. Physiol. Anim. Nutr. 2004, 88, 138-142.
16. Kerr, K.R.; Morris, C.L.; Burke, S.L.; Swanson, K.S. Influence of dietary fiber type and amount on energy and nutrient digestibility, fecal characteristics, and fecal fermentative end-product concentrations in captive exotic felids fed a raw beef-based diet. J. Anim. Sci. 2013, 91, 2199-2210.
17. Swanson, K.S.; Grieshop, C.M.; Clapper, G.M.; Shields, R.G., Jr.; Belay, T.; Merchen, N.R.; Fahey, G.C., Jr. Fruit and vegetable fiber fermentation by gut microflora from canines. J. Anim. Sci. 2002, 79, 919-926.
18. Fahey, G.C., Jr.; Merchen, N.R.; Corbin, J.E.; Hamilton, A.K.; Serbe, K.A.; Hirakawa, D.A. Dietary fiber for dogs: II. Iso-total dietary fiber (TDF) additions of divergent fiber sources to dog diets and their effects on nutrient intake, digestibility, metabolizable energy and digesta mean retention time. J. Anim. Sci. 1990, 68, 4229-4235.
19. Fahey, G.C.; Merchen, N.R.; Corbin, J.E.; Hamilton, A.K.; Bauer, L.L.; Titgemeyer, R.C.; Hirakawa, D.A. Dietary fiber for dogs: III. Effects of beet pulp and oat fiber additions to dog diets on nutrient intake, digestibility, metabolizable energy and digesta mean retention time. J. Anim. Sci. 1992, 70, 1169-1174.
20. Kerley, M.S.; Garleb, K.A.; Fahey, G.C., Jr.; Berger, L.L.; Moore, K.J.; Phillips, G.N.; Gould, J.M. Effects of alkaline hydrogen peroxide treatment of cotton and wheat straw on cellulose crystallinity and on composition and site and extent of disappearance of wheat straw cell wall phenolics and monosaccharides by sheep. J. Anim. Sci. 1988, 66, 3235-3244.
21. Guillon, F.; Auffret, A.; Robertson, J.A.; Thibault, J.F.; Barry, J.L. Relationship between physical characteristics of sugar beet fibre and its fermentability by human feacal flora. Carb. Polym. 1998, 37, 185-197.
22. Muir, H.E.; Murray, S.M.; Fahey, G.C., Jr.; Merchen, N.R.; Reinhart, G.A. Nutrient digestion by ileal cannulated dogs as affected by dietary fibers with various fermentation characteristics. J. Anim. Sci. 1996, 74, 1641-1648.
23. Middelbos, I.S.; Fastinger, N.D.; Fahey, G.C., Jr. Evaluation of fermentable oligosaccharides in diets fed to dogs in comparison to fiber standards. J. Anim. Sci. 2007, 85, 3033-3044.
24. Hendriks, W.H.; Sritharan, K. Apparent ileal and fecal digestibility of dietary protein is different in dogs. J. Nutr. 2002, 132, 1692-1694.
25. Zentek, J.; Meyer, H. Normal handling of diets-are all dogs created equal? J. Small Anim. Pract. 1995, 36, 354-359.
26. Howard, M.D.; Kerley, M.S.; Sunvold, G.D.; Reinhart, G.A. Source of dietary fiber fed to dogs affects nitrogen and energy metabolism and intestinal microflora populations. Nutr. Res. 2000, 20, 1473-1484.
27. Hesta, M.; Hoornaert, E.; Verlinden, A.; Janssens, G.P.J. The effect of oligofructose on urea metabolism and faecal odour components in cats. J. Anim. Physiol. Anim. Nutr. 2005, 89, 208-214.
28. Verbrugghe, A.; Janssens, G.P.J.; Meininger, E.; Daminet, S.; Piron, K.; Vanhaecke, L.; Wuyts, B.; Buyse, J.; Hesta, M. Intestinal fermentation modulates postprandial acylcarnitine profile and nitrogen metabolism in a true carnivore: The domestic cat (Felis catus). Br. J. Nutr. 2010, 104, 972-979.
29. Yadav, M.P.; Moreau, R.A.; Hicks, K.B. Phenolic acids, lipids, and proteins associated with purified corn fiber arabinoxylans. J. Agric. Food Chem. 2007, 55, 943-947.
30. NRC. Nutrient Requirements of Dogs and Cats, 2nd ed.; National Academies Press: Washington, DC, USA, 2006.
31. Guevara, M.A.; Bauer, L.L.; Abbas, C.A.; Beery, K.E.; Holzgraefe, D.P.; Cecava, M.J.; Fahey, G.C., Jr. Chemical composition, in vitro fermentation characteristics, and in vivo digestibility responses by dogs to select corn fibers. J. Agric. Food Chem. 2008, 56, 1619-1626.
32. Wilson, T.A.; DeSimone, A.P.; Romano, C.A.; Nicolosi, R.J. Corn fiber oil lowers plasma cholesterol levels and increases cholesterol excretion greater than corn oil and similar to diets containing soy sterols and soy stanols in hamsters. J. Nutr. Biochem. 2000, 11, 443-449.
33. De Godoy, M.R.C.; Bauer, L.L.; Parsons, C.M.; Fahey, G.C., Jr. Select corn coproducts from the ethanol industry and their potential as ingredients in pet foods. J. Anim. Sci. 2009, 87, 189-199.
34. De Godoy, M.R.C.; Bauer, L.L.; Parsons, C.M.; Swanson, K.S.; Fahey, G.C., Jr. In vitro hydrolytic digestion, glycemic response in dogs, and true metabolizable energy content of soluble corn fibers. J. Anim. Sci. 2013, submitted for publication.
35. De Godoy, M.R.C.; Bauer, L.L.; Parsons, C.M.; Swanson, K.S.; Fahey, G.C., Jr. Blending of soluble corn fiber with pullulan, sorbitol, or fructose attenuates glycemic and insulinemic responses in the dog and affects hydrolytic digestion in vitro. J. Anim. Sci. 2013, in press.
36. Knapp, B.K.; Parsons, C.M.; Bauer, L.L.; Swanson, K.S.; Fahey, G.C., Jr. Soluble fiber dextrins and pullulans vary in extent of hydrolytic digestion in vitro and in energy value and attenuate glycemic and insulinemic responses in dogs. J. Agric. Food Chem. 2010, 58, 1355-1363.
37. Knapp, B.K.; Bauer, L.L.; Swanson, K.S.; Tappenden, K.A.; Fahey, G.C., Jr.; de Godoy, M.R.C. Soluble fiber dextrin and soluble corn fiber supplementation modify indices of health in cecum and colon of Sprague-Dawley rats. Nutrients 2013, 5, 396-410.
38. Vester Boler, B.M.; Serao, M.C.R.; Bauer, L.L.; Staeger, M.A.; Boileau, T.W.; Swanson, S.S.; Fahey, G.C., Jr. Digestive physiological outcomes related to polydextrose and soluble maize fibre consumption by healthy adult men. Br. J. Nutr. 2011, 106, 1864-1871.
39. Maathuis, A.; Hoffman, A.; Evans, A.; Sanders, L.; Venema, K. The effect of the undigested fraction of maize products on the activity and composition of the microbiota determined in a dynamic in vitro model of the human proximal large intestine. J. Am. Coll. Nutr. 2009, 28, 657-666.
40. Walter, R.H.; Rao, M.A.; Sherman, R.M.; Cooley, H.J. Edible fibre from apple pomace. J. Food Sci. 1985, 60, 747-749.
41. Fischer, J. Fruit Fibers. In Fiber Ingredients: Food Applications and Health Benefits; Cho, S.S., Samuel, P., Eds.; CRC Press, Taylor & Francis Group: Boca Raton, FL, USA, 2009; pp. 427-438.
42. Fahey, G.C., Jr.; Flickinger, E.A.; Grieshop, C.M.; Swanson, K.S. The Role of Dietary Fiber in Companion Animal Nutrition. In Dietary Fibre: Bio-Active Carbohydrates for Food and Feed; Van der Kamp, J.W., Ed.; Wageningen Academic Publishers: Wageningen, The Netherlands, 2004; pp. 295-328.
43. Fekete, S.; Hullar, I.; Andrasofszky, E.; Rigo, Z.; Berkenyi, T. Reduction of the energy density of cat foods by increasing their fibre content with a view to nutrients' digestibility. J. Anim. Physiol. Anim. Nutr. 2001, 85, 200-204.
44. Ryan, E. Bioactive food components and health properties of rice bran. JAVMA 2011, 238, 593-600.
45. Kahlon, T.S. Rice Bran: Production, Composition, Functionality and Food Applications, Physiological Benefits. In Fiber Ingredients: Food Applications and Health Benefits; Cho, S.S., Samuel, P., Eds.; CRC Press, Taylor & Francis Group: Boca Raton, FL, USA, 2009; pp. 305-322.
46. Cicero, A.F.G.; Derosa, G. Rice bran and its main components: Potential role in the management of coronary risk factors. Curr. Topics Nutr. Res. 2005, 3, 29-46.
47. Spears, J.K.; Grieshop, C.M.; Fahey, G.C., Jr. Evaluation of stabilized rice bran as an ingredient in dry extruded dog diets. J. Anim. Sci. 2004, 82, 1122-1135.
48. Ogué-Bon, E.; Khoo, C.; Hoyles, L.; McCartney, A.L.; Gibson, G.R.; Rastall, R.A. In vitro fermentation of rice bran combined with Lactobacillus acidophilus 14150B or Bifidobacterium longum 05 by the canine feacal microbiota. FEMS 2011, 75, 365-376.
49. Stratton-Phelps, M.; Backus, R.C.; Rogers, Q.R.; Fascetti, A.J. Dietary rice bran decreases plasma and whole-blood taurine in cats. J. Nutr. 2002, 132, 1745S-1747S.
50. Foster, G.M.; Raina, K.; Kumar, A.; Kumar, S.; Agarwal, R.; Chen, M.H.; Bauer, J.E.; McClung, A.M.; Ryan, E.P. Rice varietal differences in bioactive bran components for inhibition of colorectal cancer cell growth. Food Chem. 2013, 145, 1545-1552.
51. American Association of Cereal Chemists. The definition of dietary fiber. Cereal Foods World 2001, 46, 112-129.
52. Food and Drug Administration. Health Claim Notification for Whole Grain Foods, 1999. Available online: http://www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ ucm073639.htm (accessed on 12 December 2012).
53. Slavin, J.L.; Jacobs, D.; Marquart, L.; Wiemer, K. The role of whole grains in disease prevention. J. Am. Diet. Assoc. 2001, 101, 780-785.
54. Fardet, A. New hypothesis for the health-protective mechanisms of whole-grain cereals: What is beyond fibre? Nutr. Res. Rev. 2010, 23, 65-134.
55. Jones, J.M.; Englenson, J. Whole grains: Benefits and challenges. Annu. Rev. Food Technol. 2010, 1, 19-40.
56. Jonnalagadda, S.S.; Harnack, L.; Liu, R.H.; McKeown, N.; Seal, C.; Liu, S.; Fahey, G.C., Jr. Putting the whole grain puzzle together: Health benefits associated with grains-Summary of American Society for Nutrition 2010 Satellite Symposium. J. Nutr. 2011, 141, 1011S-1022S.
57. Wood, J.P. Cereal beta-glucans in diet and health. J. Cereal Sci. 2007, 46, 230-238.
58. Skendi, A.; Biliaderis, C.G.; Lazaridou, A.; Izydorczyk, M.S. Structure and rheological properties of water soluble beta-glucan from oat cultivars of Avena sativa and Avena bysantina. J. Cereal Sci. 2003, 38, 15-31.
59. Wood, P.J.; Braaten, J.T.; Scott, F.W.; Riedel, K.D.; Wolynetz, M.S.; Collins, M.W. Effect of dose and modification of viscous properties of oat gum on plasma glucose and insulin following an oral glucose load. Br. J. Nutr. 1994, 72, 731-743.
60. Queenan, K.M.; Stewart, M.L.; Smith, K.N.; Thomas, W.; Fulcher, R.G.; Slavin, J.L. Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial. Nutr. J. 2007, 6, 6.
61. Wood, P.J.; Beer, M.U. Functional Oat Products. In Functional Foods Biochemical and Processing Aspects; Mazza, G., Ed.; Technomic Publishing: Lancaster, PA, USA, 1998; pp. 1-37.
62. Vasanthan, T.; Temelli, F. Grain fractionation technologies for cereal beta-glucan concentration. Food Res. Int. 2008, 41, 876-881.
63. Guillon, F.; Champ, M. Structural and physical properties of dietary fibers, and consequences of processing on human physiology. Food Res. Int. 2003, 33, 233-245.
64. Wolever, T.M.; Jenkins, D.J.; Mueller, S.; Boctor, D.L.; Ransom, T.P.; Patten, R.; Chao, E.S.; McMillan, K.; Fulgoni, V. Method of administration influences the serum cholesterol-lowering effect of psyllium. Am. J. Clin. Nutr. 1994, 59, 1055-1059.
65. Kerckhoffs, D.A.; Hornstra, G.; Mensink, R.P. Cholesterol-lowering effect of beta-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when beta-glucan is incorporated into bread and cookies. Am. J. Clin. Nutr. 2003, 78, 221-227.
66. Biorklund, M.; van Rees, A.; Mensink, R.P.; Onning, G. Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with beta-glucans from oats or barley: A randomised dose-controlled trial. Eur. J. Clin. Nutr. 2005, 59, 1272-1281.
67. Anderson, T.G.; Tan, A.; Ganz, P.; Seelig, J. Calorimetric measurement of phospholipid interaction with methyl-beta-cyclodextrin. Biochemistry 2004, 43, 2251-2261.
68. Beer, M.U.; Wood, P.J.; Fillion, N.; Weisz, J. Effect of cooking and storage on the amount and molecular weight of (1.3,1.4)-ß-glucan extracted from oat products by an in vitro digestion system. Cereal Chem. 1997, 74, 705-709.
69. Ripsin, C.M.; Keenan, J.M.; Jacobs, D.R., Jr.; Elmer, P.J.; Welch, R.R.; van Horn, L.; Liu K.; Turnbull, W.H.; Thye, F.W.; Kestin, M. Oat products and lipid lowering. A meta-analysis. JAMA 1992, 267, 3317-3325.
70. Groner, T.; Pfeffer, E. Digestibility of organic matter and digestible energy in single ingredients of extruded dog feeds and their effect on fecal dry matter concentration and consistency. J. Anim. Physiol. Anim. Nutr. 1997, 77, 214-220.
71. Swanson, K.S.; Grieshop, C.M.; Flickinger, E.A.; Bauer, L.L.; Healy, H.P.; Dawson, K.; Merchen, N.R.; Fahey, G.C., Jr. Supplemental fructooligosaccharides and mannanoligosaccharides influence immune function, ileal and total tract nutrient digestibilities, microbial populations and concentrations of protein catabolites in the large bowel of dogs. J. Nutr. 2002, 132, 980-989.
72. Owusu-Asiedu, A.; Patience, J.F.; Laarveld, B.; van Kessel, A.G.; Simmins, P.H.; Zijlstra, R.T. Effects of guar gum and cellulose on digesta passage rate, ileal microbial populations, energy and protein digestibility, and performance of grower pigs. J. Anim. Sci. 2006, 84, 843-852.
73. Bray, G.A. The underlying basis for obesity: Relationship to cancer. J. Nutr. 2002, 132, 3451S-3455S.
74. Schneeman, B.O. Dietary fiber and gastrointestinal function. Nutr. Res. 1998, 18, 625-632.
75. Le Goff, G.; Noblet, J. Comparative total tract digestibility of dietary energy and nutrients in growing pigs and adult sows. J. Anim. Sci. 2001, 79, 2418-2427.
76. Dunaif, G.; Schneeman, B.O. The effect of dietary fiber on human pancreatic enzyme activity in vitro. Am. J. Clin. Nutr. 1981, 34, 1034-1035.
77. Panahi, S.; Ezatagha, A.; Temelli, F.; Vasanthan, T.; Vuksan, V. Beta-glucan from two sources of oat concentrates affect postprandial glycemia in relation to the level of viscosity. J. Am. Coll. Nutr. 2007, 26, 639-644.
78. Juvonen, K.R.; Purhonen, A.K.; Salmenkallio-Marttola, M.; Lahteenmaki, L.; Laaksonen, D.E.; Herzig, K.H.; Uusitupa, M.I.; Poutanen, K.S.; Karhunen, L.J. Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans. J. Nutr. 2009, 139, 461-466.
79. Nazare, J.A.; Normand, S.; Triantafyllou, A.O.; Brac de la Perriere, A.; Desage, M.; Laville, M. Modulation of the postprandial phase by beta-glucan in overweight subjects: Effects on glucose and insulin kinetics. Mol. Nutr. Food Res. 2009, 53, 361-369.
80. Kim, H.; Stote, K.S.; Behall, K.M.; Spears, K.; Vinyard, B.; Conway, J.M. Glucose and insulin responses to whole grain breakfasts varying in soluble fiber, beta-glucan: A dose response study in obese women with increased risk for insulin resistance. Eur. J. Nutr. 2009, 48, 170-175.
81. Liatis, S.; Tsapogas, P.; Chala, E.; Dimosthenopoulos, C.; Kyriakopoulos, K.; Kapantais, E.; Katsilambros, N. The consumption of bread enriched with beta-glucan reduces LDL-cholesterol and improves insulin resistance in patients with type 2 diabetes. Diabetes Metab. 2009, 35, 115-120.
82. Frank, J.; Sundberg, B.; Kamal-Eldin, A.; Vessby, B.; Aman, P. Yeast-leavened oat breads with high or low molecular weight beta-glucan do not differ in their effects on blood concentrations of lipids, insulin, or glucose in humans. J. Nutr. 2004, 134, 1384-1388.
83. Bach Knudsen, K.E.; Jorgensen, H.; Canibe, N. Quantification of the absorption of nutrients derived from carbohydrate assimilation: Model experiment with catheterised pigs fed on wheat-or oat-based rolls. Br. J. Nutr. 2000, 84, 449-458.
84. Bach Knudsen, K.E.; Serena, A.; Kjaer, A.K.; Jorgensen, H.; Engberg, R. Rye bread enhances the production and plasma concentration of butyrate but not the plasma concentrations of glucose and insulin in pigs. J. Nutr. 2005, 135, 1696-1704.
85. De Godoy, M.R.C. Fish Oil and Barley Supplementation of Diets for Adult Dogs: Effects on Lipid and Protein Metabolism, Nutrient Digestibility, Fecal Quality, and Postprandial Glycemia. Ph.D. Thesis, University of Kentucky, Lexington, MA, USA, 2011; pp. 96-103.
86. Adolphe, J.L.; Murray, D.D.; Huang, Q.; Silver, T.I.; Weber, L.P. Postprandial impairment of flow-mediated dilation and elevated methylglyoxal after simple but not complex carbohydrate consumption in dogs. Nutr. Res. 2012, 32, 273-284.