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Volumn 11, Issue 7, 2013, Pages 2259-2281

Alternative sources of n-3 long-chain polyunsaturated fatty acids in marine microalgae

Author keywords

DHA; EPA; Marine microalgae; N 3 long chain polyunsaturated fatty acids

Indexed keywords

A2 EPA PURE; ALGAEBIO OMEGA 3 ORIGINS; DHA ALGAE; DHAID; DOCOSAHEXAENOIC ACID; EICOOIL; FISH OIL; ICOSAPENTAENOIC ACID; ICOSAPENTAENOIC ACID PLUS DOCOSAHEXAENOIC ACID; LIFE'S DHA; LIFE'S DHA PLUS EPA; LONG CHAIN FATTY ACID; OMEGA 3 FATTY ACID; SOURCE OIL; UNCLASSIFIED DRUG;

EID: 84880868350     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md11072259     Document Type: Review
Times cited : (245)

References (133)
  • 2
    • 70349505956 scopus 로고    scopus 로고
    • Microalgae for biodiesel production and other applications
    • Mata, T.M.; Martins, A.A.; Caetano, N.S. Microalgae for biodiesel production and other applications. Renew. Sust. Energ. Rev. 2010, 14, 217-232.
    • (2010) Renew. Sust. Energ. Rev. , vol.14 , pp. 217-232
    • Mata, T.M.1    Martins, A.A.2    Caetano, N.S.3
  • 3
    • 77954407208 scopus 로고    scopus 로고
    • Integrating lipids and contaminants in aquatic ecology and ecotoxicology
    • Arts, M.T. Brett, M.T. Kainz, M. Eds. Springer: New York, NY, USA
    • Kainz, M.J.; Fisk, A.T. Integrating Lipids and Contaminants in Aquatic Ecology and Ecotoxicology. In Lipids in Aquatic Ecosystems; Arts, M.T., Brett, M.T., Kainz, M., Eds.; Springer: New York, NY, USA, 2009; pp. 93-114.
    • (2009) Lipids in Aquatic Ecosystems , pp. 93-114
    • Kainz, M.J.1    Fisk, A.T.2
  • 4
    • 84862636812 scopus 로고    scopus 로고
    • Microalgae in the postgenomic era: A blooming reservoir for new natural products
    • Sasso, S.; Pohnert, G.; Lohr, M.; Mittag, M.; Hertweck, C. Microalgae in the postgenomic era: A blooming reservoir for new natural products. FEMS Microbiol. Rev. 2012, 36, 761-785.
    • (2012) FEMS Microbiol. Rev. , vol.36 , pp. 761-785
    • Sasso, S.1    Pohnert, G.2    Lohr, M.3    Mittag, M.4    Hertweck, C.5
  • 5
    • 80052640511 scopus 로고    scopus 로고
    • Lc-pufa from photosynthetic microalgae: Occurrence, biosynthesis, and prospects in biotechnology
    • Khozin-Goldberg, I.; Iskandarov, U.; Cohen, Z. LC-PUFA from photosynthetic microalgae: Occurrence, biosynthesis, and prospects in biotechnology. Appl. Microbiol. Biot. 2011, 91, 905-915.
    • (2011) Appl. Microbiol. Biot. , vol.91 , pp. 905-915
    • Khozin-Goldberg, I.1    Iskandarov, U.2    Cohen, Z.3
  • 6
    • 26844565513 scopus 로고    scopus 로고
    • Omega-3/6 fatty acids: Alternative sources of production
    • Ward, O.P.; Singh, A. Omega-3/6 fatty acids: Alternative sources of production. Process Biochem. 2005, 40, 3627-3652.
    • (2005) Process Biochem , vol.40 , pp. 3627-3652
    • Ward, O.P.1    Singh, A.2
  • 7
    • 84867138378 scopus 로고    scopus 로고
    • Microalgal biofactories: A promising approach towards sustainable omega-3 fatty acid production
    • Adarme-Vega, T.C.; Lim, D.K.Y.; Timmins, M.; Vernen, F.; Li, Y.; Schenk, P.M. Microalgal biofactories: A promising approach towards sustainable omega-3 fatty acid production. Microb. Cell Fact. 2012, 11, 1-10.
    • (2012) Microb. Cell Fact , vol.11 , pp. 1-10
    • Adarme-Vega, T.C.1    Lim, D.K.Y.2    Timmins, M.3    Vernen, F.4    Li, Y.5    Schenk, P.M.6
  • 9
    • 84965183779 scopus 로고
    • Fat metabolism in alaskan eskimos
    • Wilber, C.G.; Levine, V.E. Fat metabolism in Alaskan eskimos. Exp. Med. Surg. 1950, 8, 422-425.
    • (1950) Exp. Med. Surg , vol.8 , pp. 422-425
    • Wilber, C.G.1    Levine, V.E.2
  • 10
    • 0018152134 scopus 로고
    • Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis
    • Dyerberg, J.; Bang, H.O.; Stoffersen, E.; Moncada, S.; Vane, J.R. Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis. Lancet 1978, 2, 117-119.
    • (1978) Lancet , vol.2 , pp. 117-119
    • Dyerberg, J.1    Bang, H.O.2    Stoffersen, E.3    Moncada, S.4    Vane, J.R.5
  • 11
  • 12
    • 0023276149 scopus 로고
    • A new era for science in nutrition
    • Leaf, A.; Weber, P.C. A new era for science in nutrition. Am. J. Clin. Nutr. 1987, 45, 1048-1053.
    • (1987) Am. J. Clin. Nutr , vol.45 , pp. 1048-1053
    • Leaf, A.1    Weber, P.C.2
  • 13
    • 46449123205 scopus 로고    scopus 로고
    • The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases
    • Simopoulos, A.P. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp. Biol. Med. 2008, 233, 674-688.
    • (2008) Exp. Biol. Med. , vol.233 , pp. 674-688
    • Simopoulos, A.P.1
  • 14
    • 84919847125 scopus 로고    scopus 로고
    • Human life: Caught in the food web
    • Arts, M.T. Brett, M.T. Kainz, M.J. Eds. Springer: New York, NY, USA
    • Lands, W.E.M. Human Life: Caught in the Food Web. In Lipids in Aquatic Ecosystems; Arts, M.T., Brett, M.T., Kainz, M.J., Eds.; Springer: New York, NY, USA, 2009; pp. 327-354.
    • (2009) Lipids in Aquatic Ecosystems , pp. 327-354
    • Lands, W.E.M.1
  • 16
    • 33746813253 scopus 로고    scopus 로고
    • Healthy intakes of n-3 and n-6 fatty acids: Estimations considering worldwide diversity
    • Hibbeln, J.R.; Nieminen, L.R.G.; Blasbalg, T.L.; Riggs, J.A.; Lands, W.E.M. Healthy intakes of n-3 and n-6 fatty acids: Estimations considering worldwide diversity. Am. J. Clin. Nutr. 2006, 83, 1483-1493.
    • (2006) Am. J. Clin. Nutr , vol.83 , pp. 1483-1493
    • Hibbeln, J.R.1    Nieminen, L.R.G.2    Blasbalg, T.L.3    Riggs, J.A.4    Lands, W.E.M.5
  • 17
    • 77957885616 scopus 로고    scopus 로고
    • Blood eicosapentaenoic and docosahexaenoic acids predict all-cause mortality in patients with stable coronary heart disease the heart and soul study
    • Pottala, J.V.; Garg, S.; Cohen, B.E.; Whooley, M.A.; Harris, W.S. Blood eicosapentaenoic and docosahexaenoic acids predict all-cause mortality in patients with stable coronary heart disease the heart and soul study. Circ. Cardiovasc. Qual. Outcomes 2010, 3, 406-412.
    • (2010) Circ. Cardiovasc. Qual. Outcomes , vol.3 , pp. 406-412
    • Pottala, J.V.1    Garg, S.2    Cohen, B.E.3    Whooley, M.A.4    Harris, W.S.5
  • 18
    • 33745607390 scopus 로고    scopus 로고
    • Diet and lifestyle recommendations revision 2006-A scientific statement from the american heart association nutrition committee
    • Lichtenstein, A.H.; Appel, L.J.; Brands, M.; Carnethon, M.; Daniels, S.; Franch, H.A. Diet and lifestyle recommendations revision 2006-A scientific statement from the American Heart Association Nutrition Committee. Circulation 2006, 114, 82-96.
    • (2006) Circulation , vol.114 , pp. 82-96
    • Lichtenstein, A.H.1    Appel, L.J.2    Brands, M.3    Carnethon, M.4    Daniels, S.5    Franch, H.A.6
  • 19
    • 0037137299 scopus 로고    scopus 로고
    • Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease
    • Kris-Etherton, P.M.; Harris, W.S.; Appel, L.J. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002, 106, 2747-2757.
    • (2002) Circulation , vol.106 , pp. 2747-2757
    • Kris-Etherton, P.M.1    Harris, W.S.2    Appel, L.J.3
  • 20
    • 33747104166 scopus 로고    scopus 로고
    • Secondary prevention of coronary artery disease with omega-3 fatty acids
    • Jacobson, T.A. Secondary prevention of coronary artery disease with omega-3 fatty acids. Am. J. Cardiol. 2006, 98, 61-70.
    • (2006) Am. J. Cardiol. , vol.98 , pp. 61-70
    • Jacobson, T.A.1
  • 21
    • 33747188960 scopus 로고    scopus 로고
    • Antiatherosclerotic and antithrombotic effects of omega-3 fatty acids
    • Robinson, J.G.; Stone, N.J. Antiatherosclerotic and antithrombotic effects of omega-3 fatty acids. Am. J. Cardiol. 2006, 98, 39-49.
    • (2006) Am. J. Cardiol , vol.98 , pp. 39-49
    • Robinson, J.G.1    Stone, N.J.2
  • 22
    • 78649434424 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated acids and cardiovascular disease: Notable ethnic differences or unfulfilled promise?
    • Patel, J.V.; Tracey, I.; Hughes, E.A.; Lip, G.Y. Omega-3 polyunsaturated acids and cardiovascular disease: Notable ethnic differences or unfulfilled promise? J. Thromb. Haemost. 2010, 8, 2095-2104.
    • (2010) J. Thromb. Haemost , vol.8 , pp. 2095-2104
    • Patel, J.V.1    Tracey, I.2    Hughes, E.A.3    Lip, G.Y.4
  • 23
    • 34147146340 scopus 로고    scopus 로고
    • The importance of fish and docosahexaenoic acid in alzheimer disease
    • Connor, W.E.; Connor, S.L. The importance of fish and docosahexaenoic acid in Alzheimer disease. Am. J. Clin. Nutr. 2007, 85, 929-930.
    • (2007) Am. J. Clin. Nutr. , vol.85 , pp. 929-930
    • Connor, W.E.1    Connor, S.L.2
  • 24
    • 84866781715 scopus 로고    scopus 로고
    • (N-3) fatty acids: Molecular role and clinical uses in psychiatric disorders
    • Prior, P.L.; Galduroz, J.C.F. (N-3) Fatty acids: Molecular role and clinical uses in psychiatric disorders. Adv. Nutr. 2012, 3, 257-265.
    • (2012) Adv. Nutr , vol.3 , pp. 257-265
    • Prior, P.L.1    Galduroz, J.C.F.2
  • 25
    • 80052235755 scopus 로고    scopus 로고
    • Differential anti-cancer effects of purified epa and dha and possible mechanisms involved
    • Serini, S.; Fasano, E.; Piccioni, E.; Cittadini, A.R.M.; Calviello, G. Differential anti-cancer effects of purified EPA and DHA and possible mechanisms involved. Curr. Med. Chem. 2011, 18, 4065-4075.
    • (2011) Curr. Med. Chem , vol.18 , pp. 4065-4075
    • Serini, S.1    Fasano, E.2    Piccioni, E.3    Cittadini, A.R.M.4    Calviello, G.5
  • 26
    • 84155170825 scopus 로고    scopus 로고
    • Docosahexaenoic acid: A natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects
    • Siddiqui, R.A.; Harvey, K.A.; Xu, Z.D.; Bammerlin, E.M.; Walker, C.; Altenburg, J.D. Docosahexaenoic acid: A natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects. BioFactors 2011, 37, 399-412.
    • (2011) BioFactors , vol.37 , pp. 399-412
    • Siddiqui, R.A.1    Harvey, K.A.2    Xu, Z.D.3    Bammerlin, E.M.4    Walker, C.5    Altenburg, J.D.6
  • 27
    • 33846930819 scopus 로고    scopus 로고
    • Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (alspac study): An observational cohort study
    • Hibbeln, J.R.; Davis, J.M.; Steer, C.; Emmett, P.; Rogers, I.; Williams, C. Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): An observational cohort study. Lancet 2007, 369, 578-585.
    • (2007) Lancet , vol.369 , pp. 578-585
    • Hibbeln, J.R.1    Davis, J.M.2    Steer, C.3    Emmett, P.4    Rogers, I.5    Williams, C.6
  • 29
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: Advances in eicosanoid biology
    • Funk, C.D. Prostaglandins and leukotrienes: Advances in eicosanoid biology. Science 2001, 294, 1871-1875.
    • (2001) Science , vol.294 , pp. 1871-1875
    • Funk, C.D.1
  • 30
    • 62749169989 scopus 로고    scopus 로고
    • A systemic review of the roles of n-3 fatty acids in health and disease
    • Riediger, N.D.; Othman, R.A.; Suh, M.; Moghadasian, M.H. A systemic review of the roles of n-3 fatty acids in health and disease. J. Am. Diet. Assoc. 2009, 109, 668-679.
    • (2009) J. Am. Diet. Assoc , vol.109 , pp. 668-679
    • Riediger, N.D.1    Othman, R.A.2    Suh, M.3    Moghadasian, M.H.4
  • 31
    • 67349173942 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale
    • Calder, P.C. Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale. Biochimie 2009, 91, 791-795.
    • (2009) Biochimie , vol.91 , pp. 791-795
    • Calder, P.C.1
  • 32
    • 84880857077 scopus 로고    scopus 로고
    • FDA, Food and Drug Administration, Food and Drug Administration: Silver Spring, MD, USA
    • FDA, Food and Drug Administration. Notice of a Claim of GRAS Status; Food and Drug Administration: Silver Spring, MD, USA, 1998.
    • (1998) Notice of a Claim of GRAS Status
  • 33
    • 84873930444 scopus 로고    scopus 로고
    • Enrichment of foods with omega-3 fatty acids: A multidisciplinary challenge
    • Gershwin, M.E. Greenwood, M.R.C. Eds. Wiley Blackwell: New York, NY, USA
    • Jacobsen, C. Enrichment of Foods with Omega-3 Fatty Acids: A Multidisciplinary Challenge. In Foods for Health in the 21st Century: A Road Map for the Future; Gershwin, M.E., Greenwood, M.R.C., Eds.; Wiley Blackwell: New York, NY, USA, 2010.
    • (2010) Foods for Health in the 21st Century: A Road Map for the Future
    • Jacobsen, C.1
  • 35
    • 33750141751 scopus 로고    scopus 로고
    • Fish intake, contaminants, and human health-evaluating the risks and the benefits
    • Mozaffarian, D.; Rimm, E.B. Fish intake, contaminants, and human health-Evaluating the risks and the benefits. J. Am. Med. Assoc. 2006, 296, 1885-1899.
    • (2006) J. Am. Med. Assoc. , vol.296 , pp. 1885-1899
    • Mozaffarian, D.1    Rimm, E.B.2
  • 36
    • 60749084189 scopus 로고    scopus 로고
    • Quantitative approach for incorporating methylmercury risks and omega-3 fatty acid benefits in developing species-specific fish consumption advice
    • Ginsberg, G.L.; Toal, B.F. Quantitative approach for incorporating methylmercury risks and omega-3 fatty acid benefits in developing species-specific fish consumption advice. Environ. Health Persp. 2009, 117, 267-275.
    • (2009) Environ. Health Persp , vol.117 , pp. 267-275
    • Ginsberg, G.L.1    Toal, B.F.2
  • 37
    • 84861130202 scopus 로고    scopus 로고
    • Dietary sources of omega 3 fatty acids: Public health risks and benefits
    • Tur, J.A.; Bibiloni, M.M.; Sureda, A.; Pons, A. Dietary sources of omega 3 fatty acids: Public health risks and benefits. Br. J. Nutr. 2012, 107, S23-S52.
    • (2012) Br. J. Nutr. , vol.107
    • Tur, J.A.1    Bibiloni, M.M.2    Sureda, A.3    Pons, A.4
  • 38
    • 84864624471 scopus 로고    scopus 로고
    • Food and Agriculture Organisation of the United Nations, FAO: Rome, Italy
    • Food and Agriculture Organisation of the United Nations. The State of World Fisheries and Aquaculture 2012; FAO: Rome, Italy, 2012.
    • (2012) The State of World Fisheries and Aquaculture 2012
  • 40
    • 84862268506 scopus 로고    scopus 로고
    • The front-end desaturase: Structure, function, evolution and biotechnological use
    • Meesapyodsuk, D.; Qiu, X. The front-end desaturase: Structure, function, evolution and biotechnological use. Lipids 2012, 47, 227-237.
    • (2012) Lipids , vol.47 , pp. 227-237
    • Meesapyodsuk, D.1    Qiu, X.2
  • 43
    • 84867085015 scopus 로고    scopus 로고
    • Top 10 functional food trends
    • Sloan, E. Top 10 functional food trends. Food Technol. 2012, 66, 33-62.
    • (2012) Food Technol , vol.66 , pp. 33-62
    • Sloan, E.1
  • 44
    • 0032891658 scopus 로고    scopus 로고
    • Commercial developments in microalgal biotechnology
    • Apt, K.E.; Behrens, P.W. Commercial developments in microalgal biotechnology. J. Phycol. 1999, 35, 215-226.
    • (1999) J. Phycol , vol.35 , pp. 215-226
    • Apt, K.E.1    Behrens, P.W.2
  • 45
    • 0031431296 scopus 로고    scopus 로고
    • Commercial production of microalgae in the asia-pacific rim
    • Lee, Y.K. Commercial production of microalgae in the Asia-Pacific rim. J. Appl. Phycol. 1997, 9, 403-411.
    • (1997) J. Appl. Phycol , vol.9 , pp. 403-411
    • Lee, Y.K.1
  • 46
    • 79959256030 scopus 로고    scopus 로고
    • Best practices in heterotrophic high-cell-density microalgal processes: Achievements, potential and possible limitations
    • Bumbak, F.; Cook, S.; Zachleder, V.; Hauser, S.; Kovar, K. Best practices in heterotrophic high-cell-density microalgal processes: Achievements, potential and possible limitations. Appl. Microbiol. Biot. 2011, 91, 31-46.
    • (2011) Appl. Microbiol. Biot. , vol.91 , pp. 31-46
    • Bumbak, F.1    Cook, S.2    Zachleder, V.3    Hauser, S.4    Kovar, K.5
  • 47
    • 77955233622 scopus 로고    scopus 로고
    • Microbial production of docosahexaenoic acid by a low temperature-Adaptive strain thraustochytriidae sp. Z105: Screening and optimization
    • Zhou, P.-P.; Lu, M.-B.; Li, W.; Yu, L.-J. Microbial production of docosahexaenoic acid by a low temperature-Adaptive strain Thraustochytriidae sp. Z105: Screening and optimization. J. Basic Microbiol. 2010, 50, 380-387.
    • (2010) J. Basic Microbiol , vol.50 , pp. 380-387
    • Zhou, P.-P.1    Lu, M.-B.2    Li, W.3    Yu, L.-J.4
  • 48
    • 32644486441 scopus 로고    scopus 로고
    • Lipids and lipid metabolism in eukaryotic algae
    • Guschina, I.A.; Harwood, J.L. Lipids and lipid metabolism in eukaryotic algae. Prog. Lipid Res. 2006, 45, 160-186.
    • (2006) Prog. Lipid Res , vol.45 , pp. 160-186
    • Guschina, I.A.1    Harwood, J.L.2
  • 49
    • 84861670154 scopus 로고    scopus 로고
    • Microbial oils and fatty acids: Effect of carbon source on docosahexaenoic acid (c22:6 n-3, dha) production by thraustochytrid strains
    • Shene, C.; Leyton, A.; Esparza, Y.; Flores, L.; Quilodran, B.; Hinzpeter, I.; Rubilar, M. Microbial oils and fatty acids: Effect of carbon source on docosahexaenoic acid (C22:6 n-3, DHA) production by thraustochytrid strains. J. Soil Sci. Plant Nutr. 2010, 10, 207-216.
    • (2010) J. Soil Sci. Plant Nutr , vol.10 , pp. 207-216
    • Shene, C.1    Leyton, A.2    Esparza, Y.3    Flores, L.4    Quilodran, B.5    Hinzpeter, I.6    Rubilar, M.7
  • 50
    • 2642702566 scopus 로고    scopus 로고
    • The role of highly unsaturated fatty acids in aquatic food web processes
    • Brett, M.T.; Muller-Navarra, D.C. The role of highly unsaturated fatty acids in aquatic food web processes. Freshw. Biol. 1997, 38, 483-499.
    • (1997) Freshw. Biol. , vol.38 , pp. 483-499
    • Brett, M.T.1    Muller-Navarra, D.C.2
  • 51
    • 0030581110 scopus 로고    scopus 로고
    • Lipids and membrane function in green algae
    • Thompson, G.A. Lipids and membrane function in green algae. Lipids Lipid Metab. 1996, 1302, 17-45.
    • (1996) Lipids Lipid Metab , vol.1302 , pp. 17-45
    • Thompson, G.A.1
  • 52
    • 0036629120 scopus 로고    scopus 로고
    • Lipid and fatty acid composition of the green oleaginous alga parietochloris incisa, the richest plant source of arachidonic acid
    • Bigogno, C.; Khozin-Goldberg, I.; Boussiba, S.; Vonshak, A.; Cohen, Z. Lipid and fatty acid composition of the green oleaginous alga Parietochloris incisa, the richest plant source of arachidonic acid. Phytochemistry 2002, 60, 497-503.
    • (2002) Phytochemistry , vol.60 , pp. 497-503
    • Bigogno, C.1    Khozin-Goldberg, I.2    Boussiba, S.3    Vonshak, A.4    Cohen, Z.5
  • 53
    • 43549102657 scopus 로고    scopus 로고
    • Microalgal triacylglycerols as feedstocks for biofuel production: Perspectives and advances
    • Hu, Q.; Sommerfeld, M.; Jarvis, E.; Ghirardi, M.; Posewitz, M.; Seibert, M.; Darzins, A. Microalgal triacylglycerols as feedstocks for biofuel production: Perspectives and advances. Plant J. 2008, 54, 621-639.
    • (2008) Plant J. , vol.54 , pp. 621-639
    • Hu, Q.1    Sommerfeld, M.2    Jarvis, E.3    Ghirardi, M.4    Posewitz, M.5    Seibert, M.6    Darzins, A.7
  • 54
    • 80052559370 scopus 로고    scopus 로고
    • Fatty acid profiles and their distribution patterns in microalgae: A comprehensive analysis of more than 2000 strains from the sag culture collection
    • Lang, I.; Hodac, L.; Friedl, T.; Feussner, I. Fatty acid profiles and their distribution patterns in microalgae: A comprehensive analysis of more than 2000 strains from the SAG culture collection. BMC Plant Biol. 2011, 11, 1-16.
    • (2011) BMC Plant Biol , vol.11 , pp. 1-16
    • Lang, I.1    Hodac, L.2    Friedl, T.3    Feussner, I.4
  • 55
    • 84880874768 scopus 로고    scopus 로고
    • Omegas everywhere
    • Grebow, J. Omegas everywhere. Nutr. Outlook Online 2012, 15, 24-40.
    • (2012) Nutr. Outlook Online , vol.15 , pp. 24-40
    • Grebow, J.1
  • 57
    • 79953267171 scopus 로고    scopus 로고
    • Identification and functional characterisation of genes encoding the omega-3 polyunsaturated fatty acid biosynthetic pathway from the coccolithophore emiliania huxleyi
    • Sayanova, O.; Haslam, R.P.; Caleron, M.V.; Ruiz-Lopez, N.; Worthy, C.; Rooks, P.; Allen, M.J.; Napier, J.A. Identification and functional characterisation of genes encoding the omega-3 polyunsaturated fatty acid biosynthetic pathway from the coccolithophore Emiliania huxleyi. Phytochemistry 2011, 72, 594-600.
    • (2011) Phytochemistry , vol.72 , pp. 594-600
    • Sayanova, O.1    Haslam, R.P.2    Caleron, M.V.3    Ruiz-Lopez, N.4    Worthy, C.5    Rooks, P.6    Allen, M.J.7    Napier, J.A.8
  • 58
    • 0029662799 scopus 로고    scopus 로고
    • The lipid composition of the coccolithophore emiliania huxleyi and its possible ecophysiological significance
    • Pond, D.W.; Harris, R.P. The lipid composition of the coccolithophore Emiliania huxleyi and its possible ecophysiological significance. J. Mar. Biol. Assoc. UK 1996, 76, 579-594.
    • (1996) J. Mar. Biol. Assoc. UK , vol.76 , pp. 579-594
    • Pond, D.W.1    Harris, R.P.2
  • 59
    • 0030018210 scopus 로고    scopus 로고
    • Regulation of the biosynthesis of 4, 7, 10, 13, 16, 19-docosahexaenoic acid
    • Luthria, D.L.; Mohammed, B.S.; Sprecher, H. Regulation of the biosynthesis of 4, 7, 10, 13, 16, 19-docosahexaenoic acid. J. Biol. Chem. 1996, 271, 16020-16025.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16020-16025
    • Luthria, D.L.1    Mohammed, B.S.2    Sprecher, H.3
  • 60
    • 45249097151 scopus 로고    scopus 로고
    • Fatty acid biosynthesis in eukaryotic photosynthetic microalgae: Identification of a microsomal delta 12 desaturase in chlamydomonas reinhardtii
    • Chi, X.; Zhang, X.; Guan, X.; Ding, L.; Li, Y.; Wang, M.; Lin, H.; Qin, S. Fatty acid biosynthesis in eukaryotic photosynthetic microalgae: Identification of a microsomal delta 12 desaturase in Chlamydomonas reinhardtii. J. Microbiol. 2008, 46, 189-201.
    • (2008) J. Microbiol , vol.46 , pp. 189-201
    • Chi, X.1    Zhang, X.2    Guan, X.3    Ding, L.4    Li, Y.5    Wang, M.6    Lin, H.7    Qin, S.8
  • 61
    • 44649185171 scopus 로고    scopus 로고
    • Oils from microorganisms
    • Shahidi, F. Ed. John Wiley & Sons: Hoboken, NJ, USA
    • Wynn, J.P.; Ratledge, C. Oils from Microorganisms. In Bailey's Industrial Oil and Fat Products; Shahidi, F., Ed.; John Wiley & Sons: Hoboken, NJ, USA, 2005.
    • (2005) Bailey's Industrial Oil and Fat Products
    • Wynn, J.P.1    Ratledge, C.2
  • 62
    • 0002101071 scopus 로고    scopus 로고
    • Production of polyunsaturated fatty acids by the microalga porphyridium cruentum
    • Cohen, Z. Ed. Taylor and Francis: London, UK
    • Cohen, Z. Production of Polyunsaturated Fatty Acids by the Microalga Porphyridium cruentum. In Production of Chemicals by Microalgae; Cohen, Z., Ed.; Taylor and Francis: London, UK, 1999.
    • (1999) Production of Chemicals by Microalgae
    • Cohen, Z.1
  • 63
    • 0030028691 scopus 로고    scopus 로고
    • Improvement of docosahexaenoic acid production in a culture of thraustochytrium aureum by medium optimization
    • Iida, I.; Nakahara, T.; Yokochi, T.; Kamisaka, Y.; Yagi, H.; Yamaoka, M.; Suzuki, M. Improvement of docosahexaenoic acid production in a culture of Thraustochytrium aureum by medium optimization. J. Ferment. Bioeng. 1996, 81, 76-78.
    • (1996) J. Ferment. Bioeng , vol.81 , pp. 76-78
    • Iida, I.1    Nakahara, T.2    Yokochi, T.3    Kamisaka, Y.4    Yagi, H.5    Yamaoka, M.6    Suzuki, M.7
  • 64
    • 0034472949 scopus 로고    scopus 로고
    • The role of triacylglycerol as a reservoir of polyunsaturated fatty acids for the rapid production of chloroplastic lipids in certain microalgae
    • Cohen, Z.; Khozin-Goldberg, I.; Adlerstein, D.; Bigogno, C. The role of triacylglycerol as a reservoir of polyunsaturated fatty acids for the rapid production of chloroplastic lipids in certain microalgae. Biochem. Soc. Trans. 2000, 28, 740-743.
    • (2000) Biochem. Soc. Trans , vol.28 , pp. 740-743
    • Cohen, Z.1    Khozin-Goldberg, I.2    Adlerstein, D.3    Bigogno, C.4
  • 65
    • 0037008886 scopus 로고    scopus 로고
    • Long chain polyunsaturated fatty acid production and partitioning to triacylglycerols in four microalgae
    • Tonon, T.; Harvey, D.; Larson, T.R.; Graham, I.A. Long chain polyunsaturated fatty acid production and partitioning to triacylglycerols in four microalgae. Phytochemistry 2002, 61, 15-24.
    • (2002) Phytochemistry , vol.61 , pp. 15-24
    • Tonon, T.1    Harvey, D.2    Larson, T.R.3    Graham, I.A.4
  • 66
    • 84866890452 scopus 로고    scopus 로고
    • Oil extraction and fatty acid characterization of nannochloropsis oculata microalgae for biodiesel applications
    • Gog, A.; Senila, L.; Roman, M.; Luca, E.; Roman, C.; Irimie, F.-D. Oil extraction and fatty acid characterization of Nannochloropsis oculata microalgae for biodiesel applications. Stud. Univ. Babes-Bol. 2012, 57, 111-118.
    • (2012) Stud. Univ. Babes-Bol , vol.57 , pp. 111-118
    • Gog, A.1    Senila, L.2    Roman, M.3    Luca, E.4    Roman, C.5    Irimie, F.-D.6
  • 67
    • 84870739112 scopus 로고    scopus 로고
    • Effect of salinity on growth, biochemical composition, and lipid productivity of nannochloropsis oculata cs 179
    • Gu, N.; Lin, Q.; Li, G.; Tan, Y.; Huang, L.; Lin, J. Effect of salinity on growth, biochemical composition, and lipid productivity of Nannochloropsis oculata CS 179. Eng. Life Sci. 2012, 12, 631-637.
    • (2012) Eng. Life Sci , vol.12 , pp. 631-637
    • Gu, N.1    Lin, Q.2    Li, G.3    Tan, Y.4    Huang, L.5    Lin, J.6
  • 69
    • 79955563658 scopus 로고    scopus 로고
    • The effect of light, salinity, and nitrogen availability on lipid production by nannochloropsis sp
    • Pal, D.; Khozin-Goldberg, I.; Cohen, Z.; Boussiba, S. The effect of light, salinity, and nitrogen availability on lipid production by Nannochloropsis sp. Appl. Microbiol. Biot. 2011, 90, 1429-1441.
    • (2011) Appl. Microbiol. Biot , vol.90 , pp. 1429-1441
    • Pal, D.1    Khozin-Goldberg, I.2    Cohen, Z.3    Boussiba, S.4
  • 70
    • 84986841089 scopus 로고
    • Lipid synthesis and fatty acid composition in nannochloropsis sp. (eustigmatophyceae) grown in a light-dark cycle
    • Sukenik, A.; Carmeli, Y. Lipid synthesis and fatty acid composition in Nannochloropsis sp. (Eustigmatophyceae) grown in a light-dark cycle. J. Phycol. 1990, 26, 463-469.
    • (1990) J. Phycol , vol.26 , pp. 463-469
    • Sukenik, A.1    Carmeli, Y.2
  • 71
    • 0042066476 scopus 로고    scopus 로고
    • Efficient use of strong light for high photosynthetic productivity: Interrelationships between the optical path, the optimal population density and cell-growth inhibition
    • Richmond, A.; Zhang, C.W.; Zarmi, Y. Efficient use of strong light for high photosynthetic productivity: Interrelationships between the optical path, the optimal population density and cell-growth inhibition. Biomol. Eng. 2003, 20, 229-236.
    • (2003) Biomol. Eng , vol.20 , pp. 229-236
    • Richmond, A.1    Zhang, C.W.2    Zarmi, Y.3
  • 72
    • 33748755185 scopus 로고    scopus 로고
    • Isolation of enhanced eicosapentaenoic acid producing mutants of nannochloropsis oculata st-6 using ethyl methane sulfonate induced mutagenesis techniques and their characterization at mrna transcript level
    • Chaturvedi, R.; Fujita, Y. Isolation of enhanced eicosapentaenoic acid producing mutants of Nannochloropsis oculata ST-6 using ethyl methane sulfonate induced mutagenesis techniques and their characterization at mRNA transcript level. Phycol. Res. 2006, 54, 208-219.
    • (2006) Phycol. Res. , vol.54 , pp. 208-219
    • Chaturvedi, R.1    Fujita, Y.2
  • 73
    • 0842331902 scopus 로고    scopus 로고
    • Growth characteristics and eicosapentaenoic acid production by nannochloropsis sp in mixotrophic conditions
    • Xu, F.; Hu, H.H.; Cong, W.; Cai, Z.L.; Ouyang, F. Growth characteristics and eicosapentaenoic acid production by Nannochloropsis sp in mixotrophic conditions. Biotechnol. Lett. 2004, 26, 51-53.
    • (2004) Biotechnol. Lett , vol.26 , pp. 51-53
    • Xu, F.1    Hu, H.H.2    Cong, W.3    Cai, Z.L.4    Ouyang, F.5
  • 74
    • 22844448561 scopus 로고    scopus 로고
    • Effects of organic carbon sources on cell growth and eicosapentaenoic acid content of nannochloropsis sp
    • Fang, X.; Wei, C.; Cai, Z.L.; Fan, O. Effects of organic carbon sources on cell growth and eicosapentaenoic acid content of Nannochloropsis sp. J. Appl. Phycol. 2004, 16, 499-503.
    • (2004) J. Appl. Phycol , vol.16 , pp. 499-503
    • Fang, X.1    Wei, C.2    Cai, Z.L.3    Fan, O.4
  • 75
    • 0033062584 scopus 로고    scopus 로고
    • Production of eicosapentaenoic acid by nannochloropsis sp cultures in outdoor tubular photobioreactors
    • Zittelli, G.C.; Lavista, F.; Bastianini, A.; Rodolfi, L.; Vincenzini, M.; Tredici, M.R. Production of eicosapentaenoic acid by Nannochloropsis sp cultures in outdoor tubular photobioreactors. J. Biotechnol. 1999, 70, 299-312.
    • (1999) J. Biotechnol , vol.70 , pp. 299-312
    • Zittelli, G.C.1    Lavista, F.2    Bastianini, A.3    Rodolfi, L.4    Vincenzini, M.5    Tredici, M.R.6
  • 76
    • 15744391523 scopus 로고    scopus 로고
    • Optimization of eicosapentaenoic acid production by phaeodactylum tricornutum in the flat panel airlift (fpa) reactor
    • Meiser, A.; Schmid-Staiger, U.; Trosch, W. Optimization of eicosapentaenoic acid production by Phaeodactylum tricornutum in the flat panel airlift (FPA) reactor. J. Appl. Phycol. 2004, 16, 215-225.
    • (2004) J. Appl. Phycol , vol.16 , pp. 215-225
    • Meiser, A.1    Schmid-Staiger, U.2    Trosch, W.3
  • 77
    • 0342264531 scopus 로고    scopus 로고
    • Modeling of eicosapentaenoic acid (epa) production from phaeodactylum tricornutum cultures in tubular photobioreactors, effects of dilution rate, tube diameter, and solar irradiance
    • Fernandez, F.G.A.; Perez, J.A.S.; Sevilla, J.M.F.; Camacho, F.G.; Grima, E.M. Modeling of eicosapentaenoic acid (EPA) production from Phaeodactylum tricornutum cultures in tubular photobioreactors. Effects of dilution rate, tube diameter, and solar irradiance. Biotechnol. Bioeng. 2000, 68, 173-183.
    • (2000) Biotechnol. Bioeng , vol.68 , pp. 173-183
    • Fernandez, F.G.A.1    Perez, J.A.S.2    Sevilla, J.M.F.3    CamacHo, F.G.4    Grima, E.M.5
  • 78
    • 0025965483 scopus 로고
    • Growth of and omega-3-fatty-Acid production by phaeodactylum tricornutum under different culture conditions
    • Yongmanitchai, W.; Ward, O.P. Growth of and omega-3-fatty-Acid production by Phaeodactylum tricornutum under different culture conditions. Appl. Environ. Microb. 1991, 57, 419-425.
    • (1991) Appl. Environ. Microb , vol.57 , pp. 419-425
    • Yongmanitchai, W.1    Ward, O.P.2
  • 79
    • 34948899756 scopus 로고    scopus 로고
    • Potential use of the herbicide quizalofop-p-ethyl for eicosapentaenoic acid overproduction by the diatom nitzschia laevis
    • Cao, X.-H.; Li, S.-Y.; Wang, C.-L.; Lu, M.-F. Potential use of the herbicide quizalofop-p-ethyl for eicosapentaenoic acid overproduction by the diatom Nitzschia laevis. Chin. J. Biotechnol. 2007, 23, 885-890.
    • (2007) Chin. J. Biotechnol , vol.23 , pp. 885-890
    • Cao, X.-H.1    Li, S.-Y.2    Wang, C.-L.3    Lu, M.-F.4
  • 80
    • 0036661106 scopus 로고    scopus 로고
    • High cell density culture of the diatom nitzschia laevis for eicosapentaenoic acid production: Fed-batch development
    • Wen, Z.Y.; Jiang, Y.; Chen, F. High cell density culture of the diatom Nitzschia laevis for eicosapentaenoic acid production: Fed-batch development. Process Biochem. 2002, 37, 1447-1453.
    • (2002) Process Biochem , vol.37 , pp. 1447-1453
    • Wen, Z.Y.1    Jiang, Y.2    Chen, F.3
  • 81
    • 34248368566 scopus 로고    scopus 로고
    • The effect of low temperature on fatty acid composition and tocopherols of the red microalga, porphyridium cruentum
    • Durmaz, Y.; Monteiro, M.; Bandarra, N.; Gokpinar, S.; Isik, O. The effect of low temperature on fatty acid composition and tocopherols of the red microalga, Porphyridium cruentum. J. Appl. Phycol. 2007, 19, 223-227.
    • (2007) J. Appl. Phycol , vol.19 , pp. 223-227
    • Durmaz, Y.1    Monteiro, M.2    Bandarra, N.3    Gokpinar, S.4    Isik, O.5
  • 82
    • 0033859543 scopus 로고    scopus 로고
    • Triacylglycerols of the red microalga porphyridium cruentum can contribute to the biosynthesis of eukaryotic galactolipids
    • Khozin-Goldberg, I.; Yu, H.Z.; Adlerstein, D.; Didi-Cohen, S.; Heimer, Y.M.; Cohen, Z. Triacylglycerols of the red microalga Porphyridium cruentum can contribute to the biosynthesis of eukaryotic galactolipids. Lipids 2000, 35, 881-889.
    • (2000) Lipids , vol.35 , pp. 881-889
    • Khozin-Goldberg, I.1    Yu, H.Z.2    Adlerstein, D.3    Didi-Cohen, S.4    Heimer, Y.M.5    Cohen, Z.6
  • 83
    • 84755160740 scopus 로고    scopus 로고
    • Effect of uv stress on the fatty acid and lipid class composition in two marine microalgae pavlova lutheri (pavlovophyceae) and odontella aurita (bacillariophyceae)
    • Guihéneuf, F.; Fouqueray, M.; Mimouni, V.; Ulmann, L.; Jacquette, B.; Tremblin, G. Effect of UV stress on the fatty acid and lipid class composition in two marine microalgae Pavlova lutheri (Pavlovophyceae) and Odontella aurita (Bacillariophyceae). J. Appl. Phycol. 2010, 22, 629-638.
    • (2010) J. Appl. Phycol , vol.22 , pp. 629-638
    • Guihéneuf, F.1    Fouqueray, M.2    Mimouni, V.3    Ulmann, L.4    Jacquette, B.5    Tremblin, G.6
  • 84
    • 59049104940 scopus 로고    scopus 로고
    • Combined effects of irradiance level and carbon source on fatty acid and lipid class composition in the microalga pavlova lutheri commonly used in mariculture
    • Guiheneuf, F.; Mimouni, V.; Ulmann, L.; Tremblin, G. Combined effects of irradiance level and carbon source on fatty acid and lipid class composition in the microalga Pavlova lutheri commonly used in mariculture. J. Exp. Mar. Biol. Ecol. 2009, 369, 136-143.
    • (2009) J. Exp. Mar. Biol. Ecol. , vol.369 , pp. 136-143
    • Guiheneuf, F.1    Mimouni, V.2    Ulmann, L.3    Tremblin, G.4
  • 85
    • 76049095347 scopus 로고    scopus 로고
    • Heterotrophic growth and nutritional aspects of the diatom cyclotella cryptica (bacillariophyceae): Effect of some environmental factors
    • Pahl, S.L.; Lewis, D.M.; Chen, F.; King, K.D. Heterotrophic growth and nutritional aspects of the diatom Cyclotella cryptica (Bacillariophyceae): Effect of some environmental factors. J. Biosci. Bioeng. 2010, 109, 235-239.
    • (2010) J. Biosci. Bioeng , vol.109 , pp. 235-239
    • Pahl, S.L.1    Lewis, D.M.2    Chen, F.3    King, K.D.4
  • 86
    • 84867755537 scopus 로고    scopus 로고
    • Culture medium optimization and lipid profiling of cylindrotheca, a lipid- And polyunsaturated fatty acid-rich pennate diatom and potential source of eicosapentaenoic acid
    • Suman, K.; Kiran, T.; Devi, U.K.; Sarma, N.S. Culture medium optimization and lipid profiling of Cylindrotheca, a lipid- And polyunsaturated fatty acid-rich pennate diatom and potential source of eicosapentaenoic acid. Bot. Mar. 2012, 55, 289-299.
    • (2012) Bot. Mar , vol.55 , pp. 289-299
    • Suman, K.1    Kiran, T.2    Devi, U.K.3    Sarma, N.S.4
  • 87
    • 0030010071 scopus 로고    scopus 로고
    • Eicosapentaenoic acid-rich biomass production by the microalga phaeodactylum tricornutum in a continuous flow reactor
    • Reis, A.; Gouveia, L.; Veloso, V.; Fernandes, H.L.; Empis, J.A.; Novais, J.M. Eicosapentaenoic acid-rich biomass production by the microalga Phaeodactylum tricornutum in a continuous flow reactor. Bioresour. Technol. 1996, 55, 83-88.
    • (1996) Bioresour. Technol , vol.55 , pp. 83-88
    • Reis, A.1    Gouveia, L.2    Veloso, V.3    Fernandes, H.L.4    Empis, J.A.5    Novais, J.M.6
  • 88
    • 0343081029 scopus 로고    scopus 로고
    • Acyl lipid composition variation related to culture age and nitrogen concentration in continuous culture of the microalga phaeodactylum tricornutum
    • Alonso, D.L.; Belarbi, E.H.; Fernandez-Sevilla, J.M.; Rodriguez-Ruiz, J.; Grima, E.M. Acyl lipid composition variation related to culture age and nitrogen concentration in continuous culture of the microalga Phaeodactylum tricornutum. Phytochemistry 2000, 54, 461-471.
    • (2000) Phytochemistry , vol.54 , pp. 461-471
    • Alonso, D.L.1    Belarbi, E.H.2    Fernandez-Sevilla, J.M.3    Rodriguez-Ruiz, J.4    Grima, E.M.5
  • 89
    • 0035874988 scopus 로고    scopus 로고
    • Trophic obligate conversion of an photoautotrophic organism through metabolic engineering
    • Zaslavskaia, L.A.; Lippmeier, J.C.; Shih, C.; Ehrhardt, D.; Grossman, A.R.; Apt, K.E. Trophic obligate conversion of an photoautotrophic organism through metabolic engineering. Science 2001, 292, 2073-2075.
    • (2001) Science , vol.292 , pp. 2073-2075
    • Zaslavskaia, L.A.1    Lippmeier, J.C.2    Shih, C.3    Ehrhardt, D.4    Grossman, A.R.5    Apt, K.E.6
  • 90
    • 0029803108 scopus 로고    scopus 로고
    • Screening of diatoms for heterotrophic eicosapentaenoic acid production
    • Tan, C.K.; Johns, M.R. Screening of diatoms for heterotrophic eicosapentaenoic acid production. J. Appl. Phycol. 1996, 8, 59-64.
    • (1996) J. Appl. Phycol , vol.8 , pp. 59-64
    • Tan, C.K.1    Johns, M.R.2
  • 91
    • 34249010247 scopus 로고    scopus 로고
    • Fatty acid and lipid class composition of the eicosapentaenoic acid-producing microalga, nitzschia laevis
    • Chen, G.-Q.; Jiang, Y.; Chen, F. Fatty acid and lipid class composition of the eicosapentaenoic acid-producing microalga, Nitzschia laevis. Food Chem. 2007, 104, 1580-1585.
    • (2007) Food Chem , vol.104 , pp. 1580-1585
    • Chen, G.-Q.1    Jiang, Y.2    Chen, F.3
  • 92
    • 39149129050 scopus 로고    scopus 로고
    • Variation of lipid class composition in nitzschia laevis as a response to growth temperature change
    • Chen, G.-Q; Jiang, Y.; Chen, F. Variation of lipid class composition in Nitzschia laevis as a response to growth temperature change. Food Chem. 2008, 109, 88-94.
    • (2008) Food Chem , vol.109 , pp. 88-94
    • Chen, G.-Q.1    Jiang, Y.2    Chen, F.3
  • 93
    • 0031348833 scopus 로고    scopus 로고
    • Downstream processing and purification of eicosapentaenoic (20:5n-3) and arachidonic acids (20:4n-6) from the microalga porphyridium cruentum
    • Gimenez, A.G.; Gonzalez, M.J.I.; Medina, A.R.; Grima, E.M.; Salas, S.G.; Cerdan, L.E. Downstream processing and purification of eicosapentaenoic (20:5n-3) and arachidonic acids (20:4n-6) from the microalga Porphyridium cruentum. Bioseparation 1998, 7, 89-99.
    • (1998) Bioseparation , vol.7 , pp. 89-99
    • Gimenez, A.G.1    Gonzalez, M.J.I.2    Medina, A.R.3    Grima, E.M.4    Salas, S.G.5    Cerdan, L.E.6
  • 94
    • 0034448508 scopus 로고    scopus 로고
    • Eicosapentaenoic and arachidonic acids purification from the red microalga porphyridium cruentum
    • Guil-Guerrero, J.L.; Belarbi, E.H.; Rebolloso-Fuentes, M.M. Eicosapentaenoic and arachidonic acids purification from the red microalga Porphyridium cruentum. Bioseparation 2000, 9, 299-306.
    • (2000) Bioseparation , vol.9 , pp. 299-306
    • Guil-Guerrero, J.L.1    Belarbi, E.H.2    Rebolloso-Fuentes, M.M.3
  • 95
    • 84872253631 scopus 로고    scopus 로고
    • The role of odontella aurita, a marine diatom rich in epa, as a dietary supplement in dyslipidemia, platelet function and oxidative stress in high-fat fed rats
    • Haimeur, A.; Ulmann, L.; Mimouni, V.; Gueno, F.; Pineau-Vincent, F.; Meskini, N.; Tremblin, G. The role of Odontella aurita, a marine diatom rich in EPA, as a dietary supplement in dyslipidemia, platelet function and oxidative stress in high-fat fed rats. Lipids Health Dis. 2012, 11, 1-13.
    • (2012) Lipids Health Dis , vol.11 , pp. 1-13
    • Haimeur, A.1    Ulmann, L.2    Mimouni, V.3    Gueno, F.4    Pineau-Vincent, F.5    Meskini, N.6    Tremblin, G.7
  • 96
    • 2142817149 scopus 로고    scopus 로고
    • Biotechnological production and applications of the omega-polyunsaturated fatty acid docosahexaenoic acid
    • Sijtsma, L.; de Swaaf, M.E. Biotechnological production and applications of the omega-polyunsaturated fatty acid docosahexaenoic acid. Appl. Microbiol. Biot. 2004, 64, 146-153.
    • (2004) Appl. Microbiol. Biot , vol.64 , pp. 146-153
    • Sijtsma, L.1    De Swaaf, M.E.2
  • 97
    • 84863012774 scopus 로고    scopus 로고
    • Effect of salinity change on biomass and biochemical composition of nannochloropsis oculata
    • Gu, N.; Lin, Q.; Li, G.; Qin, G.; Lin, J.; Huang, L. Effect of salinity change on biomass and biochemical composition of Nannochloropsis oculata. J. World Aquacult. Soc. 2012, 43, 97-106.
    • (2012) J. World Aquacult. Soc. , vol.43 , pp. 97-106
    • Gu, N.1    Lin, Q.2    Li, G.3    Qin, G.4    Lin, J.5    Huang, L.6
  • 98
    • 55949095130 scopus 로고    scopus 로고
    • Thraustochytrid marine protists: Production of pufas and other emerging technologies
    • Raghukumar, S. Thraustochytrid marine protists: Production of PUFAs and other emerging technologies. Mar. Biotechnol. 2008, 10, 631-640.
    • (2008) Mar. Biotechnol. , vol.10 , pp. 631-640
    • Raghukumar, S.1
  • 100
    • 0035197084 scopus 로고    scopus 로고
    • Eicosapentaenoic and docosahexaenoic acids production by and okara-utilizing potential of thraustochytrids
    • Fan, K.W.; Chen, F.; Jones, E.B.G.; Vrijmoed, L.L.P. Eicosapentaenoic and docosahexaenoic acids production by and okara-utilizing potential of thraustochytrids. J. Ind. Microbiol. Biot. 2001, 27, 199-202.
    • (2001) J. Ind. Microbiol. Biot. , vol.27 , pp. 199-202
    • Fan, K.W.1    Chen, F.2    Jones, E.B.G.3    Vrijmoed, L.L.P.4
  • 101
    • 77957358305 scopus 로고    scopus 로고
    • Continuous culture of the microalgae schizochytrium limacinum on biodiesel-derived crude glycerol for producing docosahexaenoic acid
    • Ethier, S.; Woisard, K.; Vaughan, D.; Wen, Z. Continuous culture of the microalgae Schizochytrium limacinum on biodiesel-derived crude glycerol for producing docosahexaenoic acid. Bioresour. Technol. 2011, 102, 88-93.
    • (2011) Bioresour. Technol , vol.102 , pp. 88-93
    • Ethier, S.1    Woisard, K.2    Vaughan, D.3    Wen, Z.4
  • 102
    • 58149159737 scopus 로고    scopus 로고
    • Study of a two-stage growth of dha-producing marine algae schizochytrium limacinum sr21 with shifting dissolved oxygen level
    • Chi, Z.; Liu, Y.; Frear, C.; Chen, S. Study of a two-stage growth of DHA-producing marine algae Schizochytrium limacinum SR21 with shifting dissolved oxygen level. Appl. Microbiol. Biot. 2009, 81, 1141-1148.
    • (2009) Appl. Microbiol. Biot , vol.81 , pp. 1141-1148
    • Chi, Z.1    Liu, Y.2    Frear, C.3    Chen, S.4
  • 103
    • 77955920244 scopus 로고    scopus 로고
    • Increase of docosahexaenoic acid production by schizochytrium sp through mutagenesis and enzyme assay
    • Lian, M.; Huang, H.; Ren, L.; Ji, X.; Zhu, J.; Jin, L. Increase of docosahexaenoic acid production by Schizochytrium sp through mutagenesis and enzyme assay. Appl. Biochem. Biotechnol. 2010, 162, 935-941.
    • (2010) Appl. Biochem. Biotechnol , vol.162 , pp. 935-941
    • Lian, M.1    Huang, H.2    Ren, L.3    Ji, X.4    Zhu, J.5    Jin, L.6
  • 104
    • 77955552169 scopus 로고    scopus 로고
    • Development of a stepwise aeration control strategy for efficient docosahexaenoic acid production by schizochytrium sp
    • Ren, L.-J.; Ji, X.-J.; Huang, H.; Qu, L.; Feng, Y.; Tong, Q.-Q.; Ouyang, P.K. Development of a stepwise aeration control strategy for efficient docosahexaenoic acid production by Schizochytrium sp. Appl. Microbiol. Biot. 2010, 87, 1649-1656.
    • (2010) Appl. Microbiol. Biot , vol.87 , pp. 1649-1656
    • Ren, L.-J.1    Ji, X.-J.2    Huang, H.3    Qu, L.4    Feng, Y.5    Tong, Q.-Q.6    Ouyang, P.K.7
  • 105
    • 34250716332 scopus 로고    scopus 로고
    • Evaluation of fatty acid extraction methods for thraustochytrium sp. Onc-t18
    • Burja, A.M.; Armenta, R.E.; Radianingtyas, H.; Barrow, C.J. Evaluation of fatty acid extraction methods for Thraustochytrium sp. ONC-T18. J. Agric. Food Chem. 2007, 55, 4795-4801.
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 4795-4801
    • Burja, A.M.1    Armenta, R.E.2    Radianingtyas, H.3    Barrow, C.J.4
  • 106
    • 79953318982 scopus 로고    scopus 로고
    • Effect of tween 80 on the growth, lipid accumulation and fatty acid composition of thraustochytrium aureum atcc 34304
    • Taoka, Y.; Nagano, N.; Okita, Y.; Izumida, H.; Sugimoto, S.; Hayashi, M. Effect of Tween 80 on the growth, lipid accumulation and fatty acid composition of Thraustochytrium aureum ATCC 34304. J. Biosci. Bioeng. 2011, 111, 420-424.
    • (2011) J. Biosci. Bioeng. , vol.111 , pp. 420-424
    • Taoka, Y.1    Nagano, N.2    Okita, Y.3    Izumida, H.4    Sugimoto, S.5    Hayashi, M.6
  • 107
    • 77953609968 scopus 로고    scopus 로고
    • Docosahexaenoic acid (c22:6n-3, dha) and astaxanthin production by thraustochytriidae sp. As4-A1 a native strain with high similitude to ulkenia sp.: Evaluation of liquid residues from food industry as nutrient sources
    • Quilodran, B.; Hinzpeter, I.; Hormazabal, E.; Quiroz, A.; Shene, C. Docosahexaenoic acid (C22:6n-3, DHA) and astaxanthin production by Thraustochytriidae sp. AS4-A1 a native strain with high similitude to Ulkenia sp.: Evaluation of liquid residues from food industry as nutrient sources. Enzym. Microb. Technol. 2010, 47, 24-30.
    • (2010) Enzym. Microb. Technol. , vol.47 , pp. 24-30
    • Quilodran, B.1    Hinzpeter, I.2    Hormazabal, E.3    Quiroz, A.4    Shene, C.5
  • 108
    • 80052472798 scopus 로고    scopus 로고
    • Production of lipids containing high levels of docosahexaenoic acid by a newly isolated microalga, aurantiochytrium sp krs101
    • Hong, W.-K., Rairakhwada, D.; Seo, P.-S.; Park, S.-Y.; Hur, B.-K.; Kim, C.H.; Seo, J.W. Production of lipids containing high Levels of docosahexaenoic acid by a newly isolated microalga, Aurantiochytrium sp KRS101. Appl. Biochem. Biotechnol. 2011, 164, 1468-1480.
    • (2011) Appl. Biochem. Biotechnol , vol.164 , pp. 1468-1480
    • Hong, W.-K.1    Rairakhwada, D.2    Seo, P.-S.3    Park, S.-Y.4    Hur, B.-K.5    Kim, C.H.6    Seo, J.W.7
  • 109
    • 84862695971 scopus 로고    scopus 로고
    • Effects of phosphorous, nitrogen, and carbon limitation on biomass composition in batch and continuous flow cultures of the heterotrophic dinoflagellate crypthecodinium cohnii
    • Pleissner, D.; Eriksen, N.T. Effects of phosphorous, nitrogen, and carbon limitation on biomass composition in batch and continuous flow cultures of the heterotrophic dinoflagellate Crypthecodinium cohnii. Biotechnol. Bioeng. 2012, 109, 2005-2016.
    • (2012) Biotechnol. Bioeng , vol.109 , pp. 2005-2016
    • Pleissner, D.1    Eriksen, N.T.2
  • 110
    • 48349103022 scopus 로고    scopus 로고
    • The use of multi-parameter flow cytometry to study the impact of n-dodecane additions to marine dinoflagellate microalga crypthecodinium cohnii batch fermentations and dha production
    • Da Silva, T.L.; Reis, A. The use of multi-parameter flow cytometry to study the impact of n-dodecane additions to marine dinoflagellate microalga Crypthecodinium cohnii batch fermentations and DHA production. J. Ind. Microbiol. Biot. 2008, 35, 875-887.
    • (2008) J. Ind. Microbiol. Biot. , vol.35 , pp. 875-887
    • Da Silva, T.L.1    Reis, A.2
  • 111
    • 0033926893 scopus 로고    scopus 로고
    • Effects of medium glucose concentration and ph on docosahexaenoic acid content of heterotrophic crypthecodinium cohnii
    • Jiang, Y.; Chen, F. Effects of medium glucose concentration and pH on docosahexaenoic acid content of heterotrophic Crypthecodinium cohnii. Process Biochem. 2000, 35, 1205-1209.
    • (2000) Process Biochem , vol.35 , pp. 1205-1209
    • Jiang, Y.1    Chen, F.2
  • 112
    • 0030283376 scopus 로고    scopus 로고
    • Production of docosahexaenoic and docosapentaenoic acids by schizochytrium sp. Isolated from yap islands
    • Nakahara, T.; Yokochi, T.; Higashihara, T.; Tanaka, S.; Yaguchi, T.; Honda, D. Production of docosahexaenoic and docosapentaenoic acids by Schizochytrium sp. isolated from Yap islands. J. Am. Oil Chem. Soc. 1996, 73, 1421-1426.
    • (1996) J. Am. Oil Chem. Soc. , vol.73 , pp. 1421-1426
    • Nakahara, T.1    Yokochi, T.2    Higashihara, T.3    Tanaka, S.4    Yaguchi, T.5    Honda, D.6
  • 113
    • 0031974060 scopus 로고    scopus 로고
    • Optimization of docosahexaenoic acid production by schizochytrium limacinum sr21
    • Yokochi, T.; Honda, D.; Higashihara, T.; Nakahara, T. Optimization of docosahexaenoic acid production by Schizochytrium limacinum SR21. Appl. Microbiol. Biot. 1998, 49, 72-76.
    • (1998) Appl. Microbiol. Biot , vol.49 , pp. 72-76
    • Yokochi, T.1    Honda, D.2    Higashihara, T.3    Nakahara, T.4
  • 114
    • 0031276127 scopus 로고    scopus 로고
    • Production of high yields of docosahexaenoic acid by schizochytrium sp. Strain sr21
    • Yaguchi, T.; Tanaka, S.; Yokochi, T.; Nakahara, T.; Higashihara, T. Production of high yields of docosahexaenoic acid by Schizochytrium sp. strain SR21. J. Am. Oil Chem. Soc. 1997, 74, 1431-1434.
    • (1997) J. Am. Oil Chem. Soc. , vol.74 , pp. 1431-1434
    • Yaguchi, T.1    Tanaka, S.2    Yokochi, T.3    Nakahara, T.4    Higashihara, T.5
  • 115
    • 33745069042 scopus 로고    scopus 로고
    • Docosahexaenoic acid production and lipid-body formation in schizochytrium limacinum sr21
    • Morita, E.; Kumon, Y.; Nakahara, T.; Kagiwada, S.; Noguchi, T. Docosahexaenoic acid production and lipid-body formation in Schizochytrium limacinum SR21. Mar. Biotechnol. 2006, 8, 319-327.
    • (2006) Mar. Biotechnol , vol.8 , pp. 319-327
    • Morita, E.1    Kumon, Y.2    Nakahara, T.3    Kagiwada, S.4    Noguchi, T.5
  • 116
    • 34247552654 scopus 로고    scopus 로고
    • Lipid characterization of mangrove thraustochytrid-schizochytrium mangrovei
    • Fan, K.-W.; Jiang, Y.; Faan, Y.-W.; Chen, F. Lipid characterization of mangrove thraustochytrid-Schizochytrium mangrovei. J. Agric. Food Chem. 2007, 55, 2906-2910.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 2906-2910
    • Fan, K.-W.1    Jiang, Y.2    Faan, Y.-W.3    Chen, F.4
  • 117
    • 58149516712 scopus 로고    scopus 로고
    • Lipid body formation by thraustochytrium aureum (atcc 34304) in response to cell age
    • Jeh, E.-J.; Kumaran, R.S.; Hur, B.-K. Lipid body formation by Thraustochytrium aureum (ATCC 34304) in response to cell age. Korean J. Chem. Eng. 2008, 25, 1103-1109.
    • (2008) Korean J. Chem. Eng. , vol.25 , pp. 1103-1109
    • Jeh, E.-J.1    Kumaran, R.S.2    Hur, B.-K.3
  • 119
    • 85049301833 scopus 로고    scopus 로고
    • FDA, Food and Drug Administration, Microalga; Food and Drug Administration: Silver Spring, MD, USA
    • FDA, Food and Drug Administration. GRAS Notice for Ulkenia DHA Oil Derived from Ulkenia sp. Microalga; Food and Drug Administration: Silver Spring, MD, USA, 2010.
    • (2010) GRAS Notice for Ulkenia DHA Oil Derived from Ulkenia Sp
  • 120
    • 84880902508 scopus 로고    scopus 로고
    • Production of high-value products by marine microalgae thraustochytrids
    • Yang, S.-T. Ed. Elsevier: Amsterdam, The Netherlands
    • Fan, K.W.; Chen, F. Production of High-Value Products by Marine Microalgae Thraustochytrids. In Bioprocessing for Value-Added Products from Renewable Resources; Yang, S.-T., Ed.; Elsevier: Amsterdam, The Netherlands, 2007.
    • (2007) Bioprocessing for Value-Added Products from Renewable Resources
    • Fan, K.W.1    Chen, F.2
  • 121
    • 0029939519 scopus 로고    scopus 로고
    • Plasma fatty acid responses, metabolic effects, and safety of microalgal and fungal oils rich in arachidonic and docosahexaenoic acids in healthy adults
    • Innis, S.M.; Hansen, J.W. Plasma fatty acid responses, metabolic effects, and safety of microalgal and fungal oils rich in arachidonic and docosahexaenoic acids in healthy adults. Am. J. Clin. Nutr. 1996, 64, 159-167.
    • (1996) Am. J. Clin. Nutr , vol.64 , pp. 159-167
    • Innis, S.M.1    Hansen, J.W.2
  • 122
    • 0033961402 scopus 로고    scopus 로고
    • The metabolism and distribution of docosapentaenoic acid (n-6) in rats and rat hepatocytes
    • Tam, P.S.Y.; Umeda-Sawada, R.; Yaguchi, T.; Akimoto, K.; Kiso, Y.; Igarashi, O. The metabolism and distribution of docosapentaenoic acid (n-6) in rats and rat hepatocytes. Lipids 2000, 35, 71-75.
    • (2000) Lipids , vol.35 , pp. 71-75
    • Tam, P.S.Y.1    Umeda-Sawada, R.2    Yaguchi, T.3    Akimoto, K.4    Kiso, Y.5    Igarashi, O.6
  • 123
    • 0035661423 scopus 로고    scopus 로고
    • Production of docosahexaenoic acid by crypthecodinium cohnii grown in a ph-Auxostat culture with acetic acid as principal carbon source
    • Ratledge, C.; Kanagachandran, K.; Anderson, A.J.; Grantham, D.J.; Stephenson, J.C. Production of docosahexaenoic acid by Crypthecodinium cohnii grown in a pH-Auxostat culture with acetic acid as principal carbon source. Lipids 2001, 36, 1241-1246.
    • (2001) Lipids , vol.36 , pp. 1241-1246
    • Ratledge, C.1    Kanagachandran, K.2    Anderson, A.J.3    Grantham, D.J.4    Stephenson, J.C.5
  • 124
    • 34547828044 scopus 로고    scopus 로고
    • Study of docosahexaenoic acid production by the heterotrophic microalga crypthecodinium cohnii ccmp 316 using carob pulp as a promising carbon source
    • Mendes, A.; Guerra, P.; Madeira, V.; Ruano, F.; da Silva, T.L.; Reis, A. Study of docosahexaenoic acid production by the heterotrophic microalga Crypthecodinium cohnii CCMP 316 using carob pulp as a promising carbon source. World J. Microb. Biot. 2007, 23, 1209-1215.
    • (2007) World J. Microb. Biot. , vol.23 , pp. 1209-1215
    • Mendes, A.1    Guerra, P.2    Madeira, V.3    Ruano, F.4    Da Silva, T.L.5    Reis, A.6
  • 125
    • 77950833467 scopus 로고    scopus 로고
    • Supercritical fluid extraction of lipids from the heterotrophic microalga crypthecodinium cohnii
    • Couto, R.M.; Simoes, P.C.; Reis, A.; da Silva, T.L.; Martins, V.H.; Sanchez-Vicente, Y. Supercritical fluid extraction of lipids from the heterotrophic microalga Crypthecodinium cohnii. Eng. Life Sci. 2010, 10, 158-164.
    • (2010) Eng. Life Sci. , vol.10 , pp. 158-164
    • Couto, R.M.1    Simoes, P.C.2    Reis, A.3    Da Silva, T.L.4    Martins, V.H.5    Sanchez-Vicente, Y.6
  • 127
    • 0027624276 scopus 로고
    • Single cell oils-have they a biotechnological future
    • Ratledge, C. Single cell oils-Have they a biotechnological future. Trends Biotechnol. 1993, 11, 278-284.
    • (1993) Trends Biotechnol , vol.11 , pp. 278-284
    • Ratledge, C.1
  • 128
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E.G.; Dyer, W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 1959, 37, 911-917.
    • (1959) Can. J. Biochem. Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 129
    • 70350060202 scopus 로고    scopus 로고
    • Comparison of several methods for effective lipid extraction from microalgae
    • Lee, J.-Y.; Yoo, C.; Jun, S.-Y.; Ahn, C.-Y.; Oh, H.-M. Comparison of several methods for effective lipid extraction from microalgae. Bioresour. Technol. 2010, 101, S75-S77.
    • (2010) Bioresour. Technol , vol.101
    • Lee, J.-Y.1    Yoo, C.2    Jun, S.-Y.3    Ahn, C.-Y.4    Oh, H.-M.5
  • 130
    • 0037119163 scopus 로고    scopus 로고
    • Development of fatty acid analysis by high-performance liquid chromatography, gas chromatography, and related techniques
    • Brondz, I. Development of fatty acid analysis by high-performance liquid chromatography, gas chromatography, and related techniques. Anal. Chim. Acta 2002, 465, 1-37.
    • (2002) Anal. Chim. Acta , vol.465 , pp. 1-37
    • Brondz, I.1
  • 131
    • 22244454716 scopus 로고    scopus 로고
    • Preparation of fatty acid methyl esters for gas-chromatographic analysis of marine lipids: Insight studies
    • Carvalho, A.P.; Malcata, F.X. Preparation of fatty acid methyl esters for gas-chromatographic analysis of marine lipids: Insight studies. J. Agric. Food Chem. 2005, 53, 5049-5059.
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 5049-5059
    • Carvalho, A.P.1    Malcata, F.X.2
  • 132
    • 34547128383 scopus 로고    scopus 로고
    • Lipid and fatty acid composition of diatoms revisited: Rapid wound-Activated change of food quality parameters influences herbivorous copepod reproductive success
    • Wichard, T.; Gerecht, A.; Boersma, M.; Poulet, S.A.; Wiltshire, K.; Pohnert, G. Lipid and fatty acid composition of diatoms revisited: Rapid wound-Activated change of food quality parameters influences herbivorous copepod reproductive success. ChemBioChem 2007, 8, 1146-1153.
    • (2007) ChemBioChem , vol.8 , pp. 1146-1153
    • Wichard, T.1    Gerecht, A.2    Boersma, M.3    Poulet, S.A.4    Wiltshire, K.5    Pohnert, G.6


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