Docosahexaenoic acid production and lipid-body formation in Schizochytrium limacinum SR21

Marine Biotechnology

Volumn 8, Issue 3, 2006, Pages 319-327

  Morita, Eiko ^a   Kumon, Yasuyuki ^b   Nakahara, Toro ^b   Kagiwada, Satoshi ^a   Noguchi, Tetsuko ^a  

^a NARA WOMEN'S UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Electron microscopy; Freeze substitution technique; Labyrinturomycota; Neutral lipid; Nile red; Phospholipid; Thraustochytrid

Indexed keywords

FREEZE SUBSTITUTION TECHNIQUE; LABYRINTUROMYCOTA; NEUTRAL LIPID; NILE RED; THRAUSTOCHYTRID;

CELL MEMBRANES; ELECTRON MICROSCOPY; ESTERS; FATTY ACIDS; LIPIDS; MICROORGANISMS; MORPHOLOGY; PHOSPHOLIPIDS;

MARINE BIOLOGY;

DOCOSAHEXAENOIC ACID; FATTY ACID; LIPID;

FATTY ACID; FUNGUS; PHOSPHOLIPID;

ANIMAL; ARTICLE; BACTERIAL SPORE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; ULTRASTRUCTURE; ZOOPLANKTON;

ANIMALS; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS; LIPIDS; SPORES; ZOOPLANKTON;

SCHIZOCHYTRIUM LIMACINUM; THRAUSTOCHYTRIIDAE;

EID: 33745069042     PISSN: 14362228     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10126-005-5060-y     Document Type: Article

References (30)

1. A Ashford WR Barclay CA Weaver TH Giddings S Zeller 2000 Electron microscopy may reveal structure of docosahexaenoic acid-rich oil within Schizochytrium sp Lipids 35 1377 1386
2. P Bajpai PK Bajpai OP Ward 1991 Production of docosahexaenoic acid by Thraustochytrium aureum Appl Microbiol Biotechnol 35 706 710
3. NG Bazan 2003 Synaptic lipid signaling: significance of polyunsaturated fatty acids and platelet-activating factor J Lipid Res 44 2221 2233
4. RD Bowles AE Hunt GB Bremer MG Duchars RA Eaton 1999 Long-chain n-3 polyunsaturated fatty acid production by members of the marine protista group the thraustochytrids: screening of isolates and optimization of docosahexaenoic acid production J Biotechnol 70 193 202
5. RA Coleman DP Lee 2004 Enzymes of triacylglycerol synthesis and their regulation Prog Lipid Res 43 134 176
6. MA Crawford K Costeloe K Ghebremeskel A Phylactos L Skirvin F Stacey 1997 Are deficits of arachidonic and docosahexaenoic acids responsible for the neural and vascular complications of preterm babies? Am J Clin Nutr 66 1032S 1041S
7. JT Deeney HM Valivullah CH Dapper DP Dylewski TW Keenan 1985 Microlipid droplets in milk secreting mammary epithelial cells: evidence that they originate from endoplasmic reticulum and are precursors of milk lipid globules Eur J Cell Biol 38 16 26
8. EF DeLong AA Yayanos 1985 Adaptation of the membrane lipids of a deep-sea bacterium to changes in hydrostatic pressure Science 228 1101 1103
9. B Ellenbogen S Aaronson S Goldstein M Belsk 1969 Polyunsaturated fatty acids of aquatic fungi: possible phylogenetic significance Comp Biochem Physiol 29 805 811
10. H Gerster 1998 Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)? Int J Vitam Nutr Res 68 159 173
11. NM Giusto SJ Pasquaré GA Salvador PI Castagnet ME Roque MG Ilincheta de Boschero 2000 Lipid metabolism in vertebrate retinal rod outer segments Prog Lipid Res 39 315 391
12. D Honda T Yokochi T Nakahara M Erata T Higashihara 1998 Schizochytrium limacinum sp. nov., a new thraustochytrid from a mangrove area in the west Pacific Ocean Mycol Res 102 439 448
13. D Honda T Yokochi T Nakahara S Raghukumar A Nakagiri K Schaumann T Higashihara 1999 Molecular phylogeny of labyrinthulids and thraustochytrids based on the sequencing of 18S ribosomal RNA gene J Eukaryot Microbiol 46 637 647
14. Y Kamisaka N Noda T Sakai K Kawasaki 1999 Lipid bodies and lipid body formation in an oleaginous fungus, Mortierella ramanniana var. angulispora Biochim Biophys Acta 1438 185 198
15. TW Keenan DP Dylewski D Ghosal BH Keon 1992 Milk lipid globule precursor release from endoplasmic reticulum reconstituted in a cell-free system Eur J Cell Biol 57 21 29
16. L Lauritzen HS Hansen MH Jørgensen KF Michaelsen 2001 The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina Prog Lipid Res 40 1 94
17. R Leber K Landl E Zinser H Ahorn A Spok SD Kohlwein F Turnowsky G Daum 1998 Dual localization of squalene epoxidase, Erg1p, in yeast reflects a relationship between the endoplasmic reticulum and lipid particles Mol Biol Cell 9 375 386
18. DJ Murphy 2001 The biogenesis and functions of lipid bodies in animals, plants and microorganisms Prog Lipid Res 40 325 438
19. T Nakahara T Yokochi T Higashihara S Tanaka T Yaguchi D Honda 1996 Production of docosahexaenoic and docosapentaenoic acids by Schizochytrium sp. isolated from Yap Islands J Am Oil Chem Soc 73 1421 1426
20. JA Napier AK Stobart PR Shewry 1996 The structure and biogenesis of plant oil bodies: the role of the ER membrane and the oleosin class of proteins Plant Mol Biol 31 945 956
21. DC Reed MA Brzezinski DA Coury WM Graham RL Petty 1999 Neutral lipids in mcroalgal spores and their role in swimming Mar Biol 133 737 744
22. NM Sanina EY Kostetsky SN Goncharova 2000 Thermotropic behaviour of membrane lipids from brown marine alga Laminaria japonica Biochem Soc Trans 28 894 896
23. A Singh OP Ward 1997 Microbial production of docosahexaenoic acid (DHA, C22:6) Adv Appl Microbiol 45 271 312
24. W Stillwell SR Wassallb 2003 Docosahexaenoic acid: membrane properties of a unique fatty acid Chem Phys Lipids 126 1 27
25. J Terrados JA Lopez-Jimenez 1996 Fatty acid composition and chilling resistance in the green alga Caulerpa prolifera (Forrskal) Lamouroux (Chlorophyta, Caulerpales) Biochem Mol Biol Int 39 863 869
26. R Uauy DR Hoffman P Peirano DG Birch EE Birch 2001 Essential fatty acids in visual and brain development Lipids 36 885 895
27. JD Weete H Kim SR Gandhi Y Wang R Dute 1997 Lipids and ultrastructure of Thraustochytrium sp. ATCC 26185 Lipids 32 839 845
28. Y Yano A Nakayama K Yoshida 1997 Distribution of polyunsaturated fatty acids in bacteria present in intestines of deep-sea fish and shallow-sea poikilothermic animals Appl Environ Microbiol 63 2572 2577
29. T Yokochi D Honda T Higashihara T Nakahara 1998 Optimization of docosahexaenoic acid production by Schizochytrium limacinum SR21 Appl Microbiol Biotechnol 49 72 76
30. D Zweytick K Athenstaedt G Daum 2000 Intracellular lipid particles of eukaryotic cells Biochim Biophys Acta 1469 101 120