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Volumn 13, Issue 5, 2013, Pages 506-518

Genetic and epigenetic studies for determining molecular targets of natural product anticancer agents

Author keywords

Cancer stem cells; Epigenetics; Genetics; MicroRNA; Natural product

Indexed keywords

ANTINEOPLASTIC AGENT; CURCUMIN; DNA METHYLTRANSFERASE 1; ENTINOSTAT; EPIGALLOCATECHIN GALLATE; FLUOROURACIL; GENISTEIN; I KAPPA B ALPHA; ISOFLAVONE DERIVATIVE; ISOFLAVONE GENISTEIN; MICRORNA; MICRORNA 200; MICRORNA 21; NANOPARTICLE; NATURAL PRODUCT; OXALIPLATIN; PACLITAXEL; PROTEIN BCL 2; RESVERATROL; SULFORAPHANE; TRANSCRIPTION FACTOR AP 1; TRIPTOLIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84880711984     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/15680096113139990033     Document Type: Article
Times cited : (33)

References (173)
  • 1
    • 67649305191 scopus 로고    scopus 로고
    • Epigenetics in cancer: Targeting chromatin modifications
    • Ellis, L.; Atadja, P. W.; Johnstone, R. W. Epigenetics in cancer: targeting chromatin modifications. Mol. Cancer Ther. 2009, 8, 1409-1420.
    • (2009) Mol. Cancer Ther , vol.8 , pp. 1409-1420
    • Ellis, L.1    Atadja, P.W.2    Johnstone, R.W.3
  • 2
    • 80054779141 scopus 로고    scopus 로고
    • Cancer Epigenetics for the 21st Century: What's Next?
    • Esteller, M. Cancer Epigenetics for the 21st Century: What's Next? Genes Cancer 2011, 2, 604-606.
    • (2011) Genes Cancer , vol.2 , pp. 604-606
    • Esteller, M.1
  • 4
    • 59249103688 scopus 로고    scopus 로고
    • Cancer prevention: Epigenetics steps up to the plate
    • Issa, J. P. Cancer prevention: epigenetics steps up to the plate. Cancer Prev. (Phila) 2008, 1, 219-222.
    • (2008) Cancer Prev. (Phila) , vol.1 , pp. 219-222
    • Issa, J.P.1
  • 5
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller, M. Epigenetics in cancer. N. Engl. J. Med. 2008, 358, 1148-1159.
    • (2008) N. Engl. J. Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 6
    • 33847613305 scopus 로고    scopus 로고
    • Epigenetics and cancer: Towards an evaluation of the impact of environmental and dietary factors
    • Herceg, Z. Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors. Mutagenesis 2007, 22, 91-103.
    • (2007) Mutagenesis , vol.22 , pp. 91-103
    • Herceg, Z.1
  • 7
    • 77956838065 scopus 로고    scopus 로고
    • Advances in understanding cancer genomes through second-generation sequencing
    • Meyerson, M.; Gabriel, S.; Getz, G. Advances in understanding cancer genomes through second-generation sequencing. Nat. Rev. Genet. 2010, 11, 685-696.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 685-696
    • Meyerson, M.1    Gabriel, S.2    Getz, G.3
  • 8
    • 77957364747 scopus 로고    scopus 로고
    • Translating cancer research into targeted therapeutics
    • de Bono, J. S.; Ashworth, A. Translating cancer research into targeted therapeutics. Nature 2010, 467, 543-549.
    • (2010) Nature , vol.467 , pp. 543-549
    • de Bono, J.S.1    Ashworth, A.2
  • 9
    • 69349093211 scopus 로고    scopus 로고
    • Environmental influences on epigenetic profiles
    • Suter, M. A.; Aagaard-Tillery, K. M. Environmental influences on epigenetic profiles. Semin. Reprod. Med. 2009, 27, 380-390.
    • (2009) Semin. Reprod. Med , vol.27 , pp. 380-390
    • Suter, M.A.1    Aagaard-Tillery, K.M.2
  • 10
    • 77955621544 scopus 로고    scopus 로고
    • Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components
    • Li, Y.; Tollefsbol, T. O. Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Curr. Med. Chem. 2010, 17, 2141-2151.
    • (2010) Curr. Med. Chem , vol.17 , pp. 2141-2151
    • Li, Y.1    Tollefsbol, T.O.2
  • 11
    • 73749085369 scopus 로고    scopus 로고
    • The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells
    • Paluszczak, J.; Krajka-Kuzniak, V.; Baer-Dubowska, W. The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells. Toxicol. Lett. 2010, 192, 119-125.
    • (2010) Toxicol. Lett , vol.192 , pp. 119-125
    • Paluszczak, J.1    Krajka-Kuzniak, V.2    Baer-Dubowska, W.3
  • 13
    • 69249096109 scopus 로고    scopus 로고
    • Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
    • Li, Y.; VandenBoom, T. G., Kong, D.; Wang, Z.; Ali, S.; Philip, P. A.; Sarkar, F. H. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res. 2009, 69, 6704-6712.
    • (2009) Cancer Res , vol.69 , pp. 6704-6712
    • Li, Y.1    Vandenboom, T.G.2    Kong, D.3    Wang, Z.4    Ali, S.5    Philip, P.A.6    Sarkar, F.H.7
  • 14
    • 70349316774 scopus 로고    scopus 로고
    • Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression
    • Sun, Q.; Cong, R.; Yan, H.; Gu, H.; Zeng, Y.; Liu, N.; Chen, J.; Wang, B. Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression. Oncol. Rep. 2009, 22, 563-567.
    • (2009) Oncol. Rep , vol.22 , pp. 563-567
    • Sun, Q.1    Cong, R.2    Yan, H.3    Gu, H.4    Zeng, Y.5    Liu, N.6    Chen, J.7    Wang, B.8
  • 16
    • 79551639050 scopus 로고    scopus 로고
    • Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
    • Wilken, R.; Veena, M. S.; Wang, M. B.; Srivatsan, E. S. Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma. Mol. Cancer 2011, 10, 12.
    • (2011) Mol. Cancer , vol.10 , pp. 12
    • Wilken, R.1    Veena, M.S.2    Wang, M.B.3    Srivatsan, E.S.4
  • 17
    • 84858308226 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the 30 years from 1981 to 2010
    • Newman, D. J.; Cragg, G. M. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Nat. Prod. 2012, 75, 311-335.
    • J. Nat. Prod , vol.2012 , Issue.75 , pp. 311-335
    • Newman, D.J.1    Cragg, G.M.2
  • 20
    • 79952364603 scopus 로고    scopus 로고
    • Epigenetic targets of bioactive dietary components for cancer prevention and therapy
    • Meeran, S. M.; Ahmed, A.; Tollefsbol, T. O. Epigenetic targets of bioactive dietary components for cancer prevention and therapy. Clin. Epigenetics 2010, 1, 101-116.
    • (2010) Clin. Epigenetics , vol.1 , pp. 101-116
    • Meeran, S.M.1    Ahmed, A.2    Tollefsbol, T.O.3
  • 21
    • 77955079184 scopus 로고    scopus 로고
    • Anti-inflammatory plant natural products for cancer therapy
    • Aravindaram, K.; Yang, N. S. Anti-inflammatory plant natural products for cancer therapy. Planta Med. 2010, 76, 1103-1117.
    • (2010) Planta Med , vol.76 , pp. 1103-1117
    • Aravindaram, K.1    Yang, N.S.2
  • 23
    • 84855826512 scopus 로고    scopus 로고
    • MicroRNAs, diet, and cancer: New mechanistic insights on the epigenetic actions of phytochemicals
    • Parasramka, M. A.; Ho, E.; Williams, D. E.; Dashwood, R. H. MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals. Mol. Carcinog. 2012, 51, 213-230.
    • (2012) Mol. Carcinog , vol.51 , pp. 213-230
    • Parasramka, M.A.1    Ho, E.2    Williams, D.E.3    Dashwood, R.H.4
  • 24
    • 56249130451 scopus 로고    scopus 로고
    • Targeting epigenetic mechanisms: Potential of natural products in cancer chemoprevention
    • Hauser, A. T.; Jung, M. Targeting epigenetic mechanisms: potential of natural products in cancer chemoprevention. Planta Med. 2008, 74, 1593-1601.
    • (2008) Planta Med , vol.74 , pp. 1593-1601
    • Hauser, A.T.1    Jung, M.2
  • 25
    • 77953198124 scopus 로고    scopus 로고
    • Regulation of microRNAs by natural agents: An emerging field in chemoprevention and chemotherapy research
    • Li, Y.; Kong, D.; Wang, Z.; Sarkar, F. H. Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research. Pharm. Res. 2010, 27, 1027-1041.
    • (2010) Pharm. Res , vol.27 , pp. 1027-1041
    • Li, Y.1    Kong, D.2    Wang, Z.3    Sarkar, F.H.4
  • 26
    • 79958160079 scopus 로고    scopus 로고
    • Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds
    • Li, Y.; Wicha, M. S.; Schwartz, J.; Sun, D. Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds. J. Nutr. Biochem. 2011, 22, 799-806.
    • (2011) J. Nutr. Biochem , vol.22 , pp. 799-806
    • Li, Y.1    Wicha, M.S.2    Schwartz, J.3    Sun, D.4
  • 27
    • 79959626747 scopus 로고    scopus 로고
    • The main anticancer bullets of the Chinese medicinal herb, thunder god vine
    • Liu, Z.; Ma, L.; Zhou, G. B. The main anticancer bullets of the Chinese medicinal herb, thunder god vine. Molecules 2011, 16, 5283-5297.
    • (2011) Molecules , vol.16 , pp. 5283-5297
    • Liu, Z.1    Ma, L.2    Zhou, G.B.3
  • 28
    • 71849116889 scopus 로고    scopus 로고
    • Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro
    • Zhao, F.; Chen, Y.; Li, R.; Liu, Y.; Wen, L.; Zhang, C. Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro. Toxicology 2010, 267, 70-79.
    • (2010) Toxicology , vol.267 , pp. 70-79
    • Zhao, F.1    Chen, Y.2    Li, R.3    Liu, Y.4    Wen, L.5    Zhang, C.6
  • 29
    • 77951932747 scopus 로고    scopus 로고
    • RNA polymerase - an important molecular target of triptolide in cancer cells
    • Pan, J. RNA polymerase - an important molecular target of triptolide in cancer cells. Cancer Lett. 2010, 292, 149-152.
    • (2010) Cancer Lett , vol.292 , pp. 149-152
    • Pan, J.1
  • 30
    • 18844383973 scopus 로고    scopus 로고
    • Herapeutic effects of Lycium barbarum polysaccharide (LBP) on irradiation or chemotherapy-induced myelosuppressive mice
    • Gong, H.; Shen, P.; Jin, L.; Xing, C.; Tang, F. Herapeutic effects of Lycium barbarum polysaccharide (LBP) on irradiation or chemotherapy-induced myelosuppressive mice. Cancer Biother. Radiopharm. 2005, 20, 155-162.
    • (2005) Cancer Biother. Radiopharm , vol.20 , pp. 155-162
    • Gong, H.1    Shen, P.2    Jin, L.3    Xing, C.4    Tang, F.5
  • 31
    • 79955602342 scopus 로고    scopus 로고
    • Selective suppression of cervical cancer Hela cells by 2-O-beta-D-glucopyranosyl-L-ascorbic acid isolated from the fruit of Lycium barbarum L
    • Zhang, Z.; Liu, X.; Wu, T.; Liu, J.; Zhang, X.; Yang, X.; Goodheart, M. J.; Engelhardt, J. F.; Wang, Y. Selective suppression of cervical cancer Hela cells by 2-O-beta-D-glucopyranosyl-L-ascorbic acid isolated from the fruit of Lycium barbarum L. Cell Biol. Toxicol. 2010, 27, 107-121.
    • (2010) Cell Biol. Toxicol , vol.27 , pp. 107-121
    • Zhang, Z.1    Liu, X.2    Wu, T.3    Liu, J.4    Zhang, X.5    Yang, X.6    Goodheart, M.J.7    Engelhardt, J.F.8    Wang, Y.9
  • 32
    • 79960202480 scopus 로고    scopus 로고
    • Comparative evaluation of the antioxidant effects of the natural vitamin C analog 2-O-beta-D-glucopyranosyl-L-ascorbic acid isolated from Goji berry fruit
    • Zhang, Z.; Liu, X.; Zhang, X.; Liu, J.; Hao, Y.; Yang, X.; Wang, Y. Comparative evaluation of the antioxidant effects of the natural vitamin C analog 2-O-beta-D-glucopyranosyl-L-ascorbic acid isolated from Goji berry fruit. Arch. Pharm. Res. 2011, 34, 801-810.
    • (2011) Arch. Pharm. Res , vol.34 , pp. 801-810
    • Zhang, Z.1    Liu, X.2    Zhang, X.3    Liu, J.4    Hao, Y.5    Yang, X.6    Wang, Y.7
  • 33
    • 70149104250 scopus 로고    scopus 로고
    • Lycium barbarum polysaccharides induce apoptosis in human prostate cancer cells and inhibits prostate cancer growth in a xenograft mouse model of human prostate cancer
    • Luo, Q.; Li, Z.; Yan, J.; Zhu, F.; Xu, R. J.; Cai, Y. Z. Lycium barbarum polysaccharides induce apoptosis in human prostate cancer cells and inhibits prostate cancer growth in a xenograft mouse model of human prostate cancer. J. Med. Food 2009, 12, 695-703.
    • (2009) J. Med. Food , vol.12 , pp. 695-703
    • Luo, Q.1    Li, Z.2    Yan, J.3    Zhu, F.4    Xu, R.J.5    Cai, Y.Z.6
  • 34
    • 79951670852 scopus 로고    scopus 로고
    • Genoprotective effects of green tea (Camellia sinensis) in human subjects: Results of a controlled supplementation trial
    • Han, K. C.; Wong, W. C.; Benzie, I. F. Genoprotective effects of green tea (Camellia sinensis) in human subjects: results of a controlled supplementation trial. Br. J. Nutr. 2011, 105, 171-179.
    • (2011) Br. J. Nutr , vol.105 , pp. 171-179
    • Han, K.C.1    Wong, W.C.2    Benzie, I.F.3
  • 35
    • 77957590316 scopus 로고    scopus 로고
    • Cancer and metastasis: Prevention and treatment by green tea
    • Khan, N.; Mukhtar, H. Cancer and metastasis: prevention and treatment by green tea. Cancer Metastasis Rev. 2010, 29, 435-445.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 435-445
    • Khan, N.1    Mukhtar, H.2
  • 36
    • 0026771060 scopus 로고
    • Green tea composition, consumption, and polyphenol chemistry
    • Graham, H. N. Green tea composition, consumption, and polyphenol chemistry. Prev. Med. 1992, 21, 334-350.
    • (1992) Prev. Med , vol.21 , pp. 334-350
    • Graham, H.N.1
  • 38
    • 0036780991 scopus 로고    scopus 로고
    • Cancer chemoprevention by tea polyphenols through modulating signal transduction pathways
    • Lin, J. K. Cancer chemoprevention by tea polyphenols through modulating signal transduction pathways. Arch Pharm. Res. 2002, 25, 561-571.
    • (2002) Arch Pharm. Res , vol.25 , pp. 561-571
    • Lin, J.K.1
  • 40
    • 64849110824 scopus 로고    scopus 로고
    • EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression
    • Gu, B.; Ding, Q.; Xia, G.; Fang, Z. EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression. Oncol. Rep. 2009, 21, 635-640.
    • (2009) Oncol. Rep , vol.21 , pp. 635-640
    • Gu, B.1    Ding, Q.2    Xia, G.3    Fang, Z.4
  • 41
    • 77950907191 scopus 로고    scopus 로고
    • The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival
    • Balasubramanian, S.; Adhikary, G.; Eckert, R. L. The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival. Carcinogenesis 2010, 31, 496-503.
    • (2010) Carcinogenesis , vol.31 , pp. 496-503
    • Balasubramanian, S.1    Adhikary, G.2    Eckert, R.L.3
  • 42
    • 84862783302 scopus 로고    scopus 로고
    • Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells
    • Chen, D.; Pamu, S.; Cui, Q.; Chan, T. H.; Dou, Q. P. Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells. Bioorg. Med. Chem., 2012, 20, 3031-3037.
    • (2012) Bioorg. Med. Chem , vol.20 , pp. 3031-3037
    • Chen, D.1    Pamu, S.2    Cui, Q.3    Chan, T.H.4    Dou, Q.P.5
  • 45
    • 73149088865 scopus 로고    scopus 로고
    • An anticancer effect of curcumin mediated by down-regulating phosphatase of regenerating liver-3 expression on highly metastatic melanoma cells
    • Wang, L.; Shen, Y.; Song, R.; Sun, Y.; Xu, J.; Xu, Q. An anticancer effect of curcumin mediated by down-regulating phosphatase of regenerating liver-3 expression on highly metastatic melanoma cells. Mol. Pharmacol. 2009, 76, 1238-1245.
    • (2009) Mol. Pharmacol , vol.76 , pp. 1238-1245
    • Wang, L.1    Shen, Y.2    Song, R.3    Sun, Y.4    Xu, J.5    Xu, Q.6
  • 46
    • 79951767903 scopus 로고    scopus 로고
    • Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells
    • Yang, J.; Cao, Y.; Sun, J.; Zhang, Y. Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells. Med. Oncol. 2010, 27, 1114-1118.
    • (2010) Med. Oncol , vol.27 , pp. 1114-1118
    • Yang, J.1    Cao, Y.2    Sun, J.3    Zhang, Y.4
  • 47
    • 78349269863 scopus 로고    scopus 로고
    • Development of curcumin as an epigenetic agent
    • Fu, S.; Kurzrock, R. Development of curcumin as an epigenetic agent. Cancer 2010, 116, 4670-4676.
    • (2010) Cancer , vol.116 , pp. 4670-4676
    • Fu, S.1    Kurzrock, R.2
  • 49
    • 55949095821 scopus 로고    scopus 로고
    • Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
    • Reuter, S.; Eifes, S.; Dicato, M.; Aggarwal, B. B.; Diederich, M. Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells. Biochem. Pharmacol. 2008, 76, 1340-1351.
    • (2008) Biochem. Pharmacol , vol.76 , pp. 1340-1351
    • Reuter, S.1    Eifes, S.2    Dicato, M.3    Aggarwal, B.B.4    Diederich, M.5
  • 50
    • 18744403080 scopus 로고    scopus 로고
    • Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation
    • Liu, H. L.; Chen, Y.; Cui, G. H.; Zhou, J. F. Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation. Acta Pharmacol. Sin. 2005, 26, 603-609.
    • (2005) Acta Pharmacol. Sin , vol.26 , pp. 603-609
    • Liu, H.L.1    Chen, Y.2    Cui, G.H.3    Zhou, J.F.4
  • 51
    • 0034928799 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by dietary polyphenolic compounds
    • Yang, C. S.; Landau, J. M.; Huang, M. T.; Newmark, H. L. Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu. Rev. Nutr. 2001, 21, 381-406.
    • (2001) Annu. Rev. Nutr , vol.21 , pp. 381-406
    • Yang, C.S.1    Landau, J.M.2    Huang, M.T.3    Newmark, H.L.4
  • 52
    • 31344441221 scopus 로고    scopus 로고
    • Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis
    • Gu, Y.; Zhu, C. F.; Iwamoto, H.; Chen, J. S. Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis. World J. Gastroenterol. 2005, 11, 6512-6517.
    • (2005) World J. Gastroenterol , vol.11 , pp. 6512-6517
    • Gu, Y.1    Zhu, C.F.2    Iwamoto, H.3    Chen, J.S.4
  • 53
    • 32944478433 scopus 로고    scopus 로고
    • Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis
    • Singh, A. V.; Franke, A. A.; Blackburn, G. L.; Zhou, J. R. Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis. Cancer Res. 2006, 66, 1851-1858.
    • (2006) Cancer Res , vol.66 , pp. 1851-1858
    • Singh, A.V.1    Franke, A.A.2    Blackburn, G.L.3    Zhou, J.R.4
  • 54
    • 46049103996 scopus 로고    scopus 로고
    • Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
    • Kikuno, N.; Shiina, H.; Urakami, S.; Kawamoto, K.; Hirata, H.; Tanaka, Y.; Majid, S.; Igawa, M.; Dahiya, R. Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. Int. J. Cancer. 2008, 123, 552-560.
    • (2008) Int. J. Cancer , vol.123 , pp. 552-560
    • Kikuno, N.1    Shiina, H.2    Urakami, S.3    Kawamoto, K.4    Hirata, H.5    Tanaka, Y.6    Majid, S.7    Igawa, M.8    Dahiya, R.9
  • 55
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials
    • Bishayee, A. Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev. Res. (Phila) 2009, 2, 409-418.
    • (2009) Cancer Prev. Res. (Phila) , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 56
    • 77954653079 scopus 로고    scopus 로고
    • Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines
    • Mao, Q. Q.; Bai, Y.; Lin, Y. W.; Zheng, X. Y.; Qin, J.; Yang, K.; Xie, L. P. Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines. Mol. Nutr. Food Res. 2010, 54, 1574-1584.
    • (2010) Mol. Nutr. Food Res , vol.54 , pp. 1574-1584
    • Mao, Q.Q.1    Bai, Y.2    Lin, Y.W.3    Zheng, X.Y.4    Qin, J.5    Yang, K.6    Xie, L.P.7
  • 57
    • 77957590701 scopus 로고    scopus 로고
    • Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases
    • Liu, P. L.; Tsai, J. R.; Charles, A. L.; Hwang, J. J.; Chou, S. H.; Ping, Y. H.; Lin, F. Y.; Chen, Y. L.; Hung, C. Y.; Chen, W. C.; Chen, Y. H.; Chong, I. W. Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases. Mol. Nutr. Food Res. 2010, 54(Suppl 2), S196-S204.
    • (2010) Mol. Nutr. Food Res , vol.54 , Issue.SUPPL. 2
    • Liu, P.L.1    Tsai, J.R.2    Charles, A.L.3    Hwang, J.J.4    Chou, S.H.5    Ping, Y.H.6    Lin, F.Y.7    Chen, Y.L.8    Hung, C.Y.9    Chen, W.C.10    Chen, Y.H.11    Chong, I.W.12
  • 58
    • 77956591357 scopus 로고    scopus 로고
    • Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells
    • Papoutsis, A. J.; Lamore, S. D.; Wondrak, G. T.; Selmin, O. I.; Romagnolo, D. F. Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells. J. Nutr. 2010, 140, 1607-1614.
    • (2010) J. Nutr , vol.140 , pp. 1607-1614
    • Papoutsis, A.J.1    Lamore, S.D.2    Wondrak, G.T.3    Selmin, O.I.4    Romagnolo, D.F.5
  • 60
    • 68949113934 scopus 로고    scopus 로고
    • SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
    • Boily, G.; He, X. H.; Pearce, B.; Jardine, K.; McBurney, M. W. SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol. Oncogene 2009, 28, 2882-2893.
    • (2009) Oncogene , vol.28 , pp. 2882-2893
    • Boily, G.1    He, X.H.2    Pearce, B.3    Jardine, K.4    McBurney, M.W.5
  • 61
    • 77449106593 scopus 로고    scopus 로고
    • Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention
    • Cheung, K. L.; Kong, A. N. Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention. AAPS J. 2010, 12, 87-97.
    • (2010) AAPS J , vol.12 , pp. 87-97
    • Cheung, K.L.1    Kong, A.N.2
  • 63
    • 0035942499 scopus 로고    scopus 로고
    • Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells
    • Chinni, S. R.; Li, Y.; Upadhyay, S.; Koppolu, P. K.; Sarkar, F. H. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene 2001, 20, 2927-2936.
    • (2001) Oncogene , vol.20 , pp. 2927-2936
    • Chinni, S.R.1    Li, Y.2    Upadhyay, S.3    Koppolu, P.K.4    Sarkar, F.H.5
  • 64
    • 0028231062 scopus 로고
    • Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: Ectopic expression of the agouti gene
    • Yen, T. T.; Gill, A. M.; Frigeri, L. G.; Barsh, G. S.; Wolff, G. L. Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: ectopic expression of the agouti gene. FASEB J. 1994, 8, 479-488.
    • (1994) FASEB J , vol.8 , pp. 479-488
    • Yen, T.T.1    Gill, A.M.2    Frigeri, L.G.3    Barsh, G.S.4    Wolff, G.L.5
  • 65
    • 0028245837 scopus 로고
    • Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage
    • Michaud, E. J.; van Vugt, M. J.; Bultman, S. J.; Sweet, H. O.; Davisson, M. T.; Woychik, R. P. Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage. Genes Dev. 1994, 8, 1463-1472.
    • (1994) Genes Dev , vol.8 , pp. 1463-1472
    • Michaud, E.J.1    van Vugt, M.J.2    Bultman, S.J.3    Sweet, H.O.4    Davisson, M.T.5    Woychik, R.P.6
  • 66
    • 41549104304 scopus 로고    scopus 로고
    • Postweaning dietary folate deficiency provided through childhood to puberty permanently increases genomic DNA methylation in adult rat liver
    • Kotsopoulos, J.; Sohn, K. J.; Kim, Y. I. Postweaning dietary folate deficiency provided through childhood to puberty permanently increases genomic DNA methylation in adult rat liver. J. Nutr. 2008, 138, 703-709.
    • (2008) J. Nutr , vol.138 , pp. 703-709
    • Kotsopoulos, J.1    Sohn, K.J.2    Kim, Y.I.3
  • 67
    • 33645633542 scopus 로고    scopus 로고
    • Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
    • Dolinoy, D. C.; Weidman, J. R.; Waterland, R. A.; Jirtle, R. L. Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ. Health Perspect. 2006, 114, 567-572.
    • (2006) Environ. Health Perspect , vol.114 , pp. 567-572
    • Dolinoy, D.C.1    Weidman, J.R.2    Waterland, R.A.3    Jirtle, R.L.4
  • 68
    • 80052009897 scopus 로고    scopus 로고
    • Epigenetic diet: Impact on the epigenome and cancer
    • Hardy, T. M.; Tollefsbol, T. O. Epigenetic diet: impact on the epigenome and cancer. Epigenomics 2011, 3, 503-518.
    • (2011) Epigenomics , vol.3 , pp. 503-518
    • Hardy, T.M.1    Tollefsbol, T.O.2
  • 69
    • 0018378083 scopus 로고
    • Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions
    • Hoffman, D. R.; Cornatzer, W. E.; Duerre, J. A. Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions. Can. J. Biochem. 1979, 57, 56-65.
    • (1979) Can. J. Biochem , vol.57 , pp. 56-65
    • Hoffman, D.R.1    Cornatzer, W.E.2    Duerre, J.A.3
  • 70
    • 77149156308 scopus 로고    scopus 로고
    • The role of histone modifications and variants in regulating gene expression in breast cancer
    • Dalvai, M.; Bystricky, K. The role of histone modifications and variants in regulating gene expression in breast cancer. J. Mammary Gland Biol. Neoplasia 2010, 15, 19-33.
    • (2010) J. Mammary Gland Biol. Neoplasia , vol.15 , pp. 19-33
    • Dalvai, M.1    Bystricky, K.2
  • 71
    • 74849127193 scopus 로고    scopus 로고
    • Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery
    • Ganesan, A.; Nolan, L.; Crabb, S. J.; Packham, G. Epigenetic therapy: histone acetylation, DNA methylation and anti-cancer drug discovery. Curr. Cancer Drug Targets 2009, 9, 963-981.
    • (2009) Curr. Cancer Drug Targets , vol.9 , pp. 963-981
    • Ganesan, A.1    Nolan, L.2    Crabb, S.J.3    Packham, G.4
  • 72
    • 0345275879 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • Fang, M. Z.; Wang, Y.; Ai, N.; Hou, Z.; Sun, Y.; Lu, H.; Welsh, W.; Yang, C. S. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res. 2003, 63, 7563-7570.
    • (2003) Cancer Res , vol.63 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5    Lu, H.6    Welsh, W.7    Yang, C.S.8
  • 73
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang, M.; Chen, D.; Yang, C. S. Dietary polyphenols may affect DNA methylation. J. Nutr. 2007, 137, 223S-228S.
    • (2007) J. Nutr , vol.137
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 74
    • 33746280556 scopus 로고    scopus 로고
    • Protective effects of green tea against prostate cancer. Expert review of anticancer therapy
    • Lee, A. H.; Fraser, M. L.; Meng, X.; Binns, C. W. Protective effects of green tea against prostate cancer. Expert review of anticancer therapy. Expert Rev. Anticancer Ther. 2006, 6, 507-513.
    • (2006) Expert Rev. Anticancer Ther , vol.6 , pp. 507-513
    • Lee, A.H.1    Fraser, M.L.2    Meng, X.3    Binns, C.W.4
  • 75
    • 67650892068 scopus 로고    scopus 로고
    • Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells
    • Gao, Z.; Xu, Z.; Hung, M. S.; Lin, Y. C.; Wang, T.; Gong, M.; Zhi, X.; Jablon, D. M.; You, L. Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells. Anticancer Res. 2009, 29, 2025-2030.
    • (2009) Anticancer Res , vol.29 , pp. 2025-2030
    • Gao, Z.1    Xu, Z.2    Hung, M.S.3    Lin, Y.C.4    Wang, T.5    Gong, M.6    Zhi, X.7    Jablon, D.M.8    You, L.9
  • 76
    • 77951225012 scopus 로고    scopus 로고
    • Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells
    • Pandey, M.; Shukla, S.; Gupta, S. Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells. Int. J. Cancer 2010, 126, 2520-2533.
    • (2010) Int. J. Cancer , vol.126 , pp. 2520-2533
    • Pandey, M.1    Shukla, S.2    Gupta, S.3
  • 77
    • 49549087270 scopus 로고    scopus 로고
    • Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells
    • Kato, K.; Long, N. K.; Makita, H.; Toida, M.; Yamashita, T.; Hatakeyama, D.; Hara, A.; Mori, H.; Shibata, T. Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells. Br. J. Cancer 2008, 99, 647-654.
    • (2008) Br. J. Cancer , vol.99 , pp. 647-654
    • Kato, K.1    Long, N.K.2    Makita, H.3    Toida, M.4    Yamashita, T.5    Hatakeyama, D.6    Hara, A.7    Mori, H.8    Shibata, T.9
  • 78
    • 67650249228 scopus 로고    scopus 로고
    • Molecular basis for cancer chemoprevention by green tea polyphenol EGCG
    • Tachibana, H. Molecular basis for cancer chemoprevention by green tea polyphenol EGCG. Forum Nutr. 2009, 61, 156-169.
    • (2009) Forum Nutr , vol.61 , pp. 156-169
    • Tachibana, H.1
  • 79
    • 39149091066 scopus 로고    scopus 로고
    • Environment, diet and CpG island methylation: Epigenetic signals in gastrointestinal neoplasia
    • Johnson, I. T.; Belshaw, N. J. Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia. Food Chem. Toxicol. 2008, 46, 1346-1359.
    • (2008) Food Chem. Toxicol , vol.46 , pp. 1346-1359
    • Johnson, I.T.1    Belshaw, N.J.2
  • 80
    • 42349103444 scopus 로고    scopus 로고
    • Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification
    • Majid, S.; Kikuno, N.; Nelles, J.; Noonan, E.; Tanaka, Y.; Kawamoto, K.; Hirata, H.; Li, L. C.; Zhao, H.; Okino, S. T.; Place, R. F.; Pookot, D.; Dahiya, R. Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification. Cancer Res. 2008, 68, 2736-2744.
    • (2008) Cancer Res , vol.68 , pp. 2736-2744
    • Majid, S.1    Kikuno, N.2    Nelles, J.3    Noonan, E.4    Tanaka, Y.5    Kawamoto, K.6    Hirata, H.7    Li, L.C.8    Zhao, H.9    Okino, S.T.10    Place, R.F.11    Pookot, D.12    Dahiya, R.13
  • 81
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • King-Batoon, A.; Leszczynska, J. M.; Klein, C. B. Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ. Mol. Mutagen. 2008, 49, 36-45.
    • (2008) Environ. Mol. Mutagen , vol.49 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 83
    • 67449084948 scopus 로고    scopus 로고
    • Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
    • Li, Y.; Liu, L.; Andrews, L. G.; Tollefsbol, T. O. Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int. J. Cancer 2009, 125, 286-296.
    • (2009) Int. J. Cancer , vol.125 , pp. 286-296
    • Li, Y.1    Liu, L.2    Andrews, L.G.3    Tollefsbol, T.O.4
  • 84
    • 57349126317 scopus 로고    scopus 로고
    • Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein
    • Tang, W. Y.; Newbold, R.; Mardilovich, K.; Jefferson, W.; Cheng, R. Y.; Medvedovic, M.; Ho, S. M. Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein. Endocrinology 2008, 149, 5922-5931.
    • (2008) Endocrinology , vol.149 , pp. 5922-5931
    • Tang, W.Y.1    Newbold, R.2    Mardilovich, K.3    Jefferson, W.4    Cheng, R.Y.5    Medvedovic, M.6    Ho, S.M.7
  • 85
    • 41649090153 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
    • Sun, M.; Estrov, Z.; Ji, Y.; Coombes, K. R.; Harris, D. H.; Kurzrock, R. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol. Cancer Ther. 2008, 7, 464-473.
    • (2008) Mol. Cancer Ther , vol.7 , pp. 464-473
    • Sun, M.1    Estrov, Z.2    Ji, Y.3    Coombes, K.R.4    Harris, D.H.5    Kurzrock, R.6
  • 86
    • 84855405573 scopus 로고    scopus 로고
    • Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression
    • Bao, B.; Ali, S.; Banerjee, S.; Wang, Z.; Logna, F.; Azmi, A. S.; Kong, D.; Ahmad, A.; Li, Y.; Padhye, S.; Sarkar, F. H. Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression. Cancer Res. 2012, 72, 335-345.
    • (2012) Cancer Res , vol.72 , pp. 335-345
    • Bao, B.1    Ali, S.2    Banerjee, S.3    Wang, Z.4    Logna, F.5    Azmi, A.S.6    Kong, D.7    Ahmad, A.8    Li, Y.9    Padhye, S.10    Sarkar, F.H.11
  • 88
    • 58349094740 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation
    • Choi, K. C.; Jung, M. G.; Lee, Y. H.; Yoon, J. C.; Kwon, S. H.; Kang, H. B.; Kim, M. J.; Cha, J. H.; Kim, Y. J.; Jun, W. J.; Lee, J. M.; Yoon, H. G. Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res. 2009, 69, 583-592.
    • (2009) Cancer Res , vol.69 , pp. 583-592
    • Choi, K.C.1    Jung, M.G.2    Lee, Y.H.3    Yoon, J.C.4    Kwon, S.H.5    Kang, H.B.6    Kim, M.J.7    Cha, J.H.8    Kim, Y.J.9    Jun, W.J.10    Lee, J.M.11    Yoon, H.G.12
  • 89
    • 73949133652 scopus 로고    scopus 로고
    • Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells
    • Tsang, W. P.; Kwok, T. T. Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells. J. Nutr. Biochem. 2010, 21, 140-146.
    • (2010) J. Nutr. Biochem , vol.21 , pp. 140-146
    • Tsang, W.P.1    Kwok, T.T.2
  • 90
    • 81855206547 scopus 로고    scopus 로고
    • Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1alpha
    • Wang, H.; Bian, S.; Yang, C. S. Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1alpha. Carcinogenesis 2011, 32, 1881-1889.
    • (2011) Carcinogenesis , vol.32 , pp. 1881-1889
    • Wang, H.1    Bian, S.2    Yang, C.S.3
  • 91
    • 61649113446 scopus 로고    scopus 로고
    • Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
    • Qin, W.; Zhu, W.; Shi, H.; Hewett, J. E.; Ruhlen, R. L.; MacDonald, R. S.; Rottinghaus, G. E.; Chen, Y. C.; Sauter, E. R. Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr. Cancer 2009, 61, 238-244.
    • (2009) Nutr. Cancer , vol.61 , pp. 238-244
    • Qin, W.1    Zhu, W.2    Shi, H.3    Hewett, J.E.4    Ruhlen, R.L.5    Macdonald, R.S.6    Rottinghaus, G.E.7    Chen, Y.C.8    Sauter, E.R.9
  • 96
    • 77649196575 scopus 로고    scopus 로고
    • Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol
    • Melkamu, T.; Zhang, X.; Tan, J.; Zeng, Y.; Kassie, F. Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol. Carcinogenesis 2010, 31, 252-258.
    • (2010) Carcinogenesis , vol.31 , pp. 252-258
    • Melkamu, T.1    Zhang, X.2    Tan, J.3    Zeng, Y.4    Kassie, F.5
  • 97
    • 84865429801 scopus 로고    scopus 로고
    • 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells
    • Beaver, L. M.; Yu, T. W.; Sokolowski, E. I.; Williams, D. E.; Dashwood, R. H.; Ho, E. 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells. Toxicol. Appl. Pharmacol. 2012, 263, 345-351.
    • (2012) Toxicol. Appl. Pharmacol , vol.263 , pp. 345-351
    • Beaver, L.M.1    Yu, T.W.2    Sokolowski, E.I.3    Williams, D.E.4    Dashwood, R.H.5    Ho, E.6
  • 98
    • 79961211147 scopus 로고    scopus 로고
    • Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): From bench to clinic
    • Banerjee, S.; Kong, D.; Wang, Z.; Bao, B.; Hillman, G. G.; Sarkar, F. H. Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): from bench to clinic. Mutat. Res. 2011, 728, 47-66.
    • (2011) Mutat. Res , vol.728 , pp. 47-66
    • Banerjee, S.1    Kong, D.2    Wang, Z.3    Bao, B.4    Hillman, G.G.5    Sarkar, F.H.6
  • 99
    • 57649119790 scopus 로고    scopus 로고
    • An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells
    • Lukiw, W. J.; Zhao, Y.; Cui, J. G. An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells. J. Biol. Chem. 2008, 283, 31315-31322.
    • (2008) J. Biol. Chem , vol.283 , pp. 31315-31322
    • Lukiw, W.J.1    Zhao, Y.2    Cui, J.G.3
  • 101
    • 84866340849 scopus 로고    scopus 로고
    • BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 cells
    • Papoutsis, A. J.; Borg, J. L.; Selmin, O. I.; Romagnolo, D. F. BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 cells. J. Nutr. Biochem. 2012, 23, 1324-1332.
    • (2012) J. Nutr. Biochem , vol.23 , pp. 1324-1332
    • Papoutsis, A.J.1    Borg, J.L.2    Selmin, O.I.3    Romagnolo, D.F.4
  • 102
    • 84869859363 scopus 로고    scopus 로고
    • Resveratrol Sensitizes AML Cells to HDAC Inhibitors via ROS-Mediated Activation of the Extrinsic Apoptotic Pathway
    • Yaseen, A.; Chen, S.; Hock, S.; Rosato, R.; Dent, P.; Dai, Y.; Grant, S. Resveratrol Sensitizes AML Cells to HDAC Inhibitors via ROS-Mediated Activation of the Extrinsic Apoptotic Pathway. Mol. Pharmacol. 2012, 82, 1030-1041.
    • (2012) Mol. Pharmacol , vol.82 , pp. 1030-1041
    • Yaseen, A.1    Chen, S.2    Hock, S.3    Rosato, R.4    Dent, P.5    Dai, Y.6    Grant, S.7
  • 103
    • 38449107684 scopus 로고    scopus 로고
    • Cell cycle control as a basis for cancer chemoprevention through dietary agents
    • Meeran, S. M.; Katiyar, S. K. Cell cycle control as a basis for cancer chemoprevention through dietary agents. Front Biosci. 2008, 13, 2191-2202.
    • (2008) Front Biosci , vol.13 , pp. 2191-2202
    • Meeran, S.M.1    Katiyar, S.K.2
  • 104
    • 23244450241 scopus 로고    scopus 로고
    • Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane
    • Traka, M.; Gasper, A. V.; Smith, J. A.; Hawkey, C. J.; Bao, Y.; Mithen, R. F. Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. J. Nutr. 2005, 135, 1865-1872.
    • (2005) J. Nutr , vol.135 , pp. 1865-1872
    • Traka, M.1    Gasper, A.V.2    Smith, J.A.3    Hawkey, C.J.4    Bao, Y.5    Mithen, R.F.6
  • 105
    • 72249122960 scopus 로고    scopus 로고
    • Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention
    • Ho, E.; Clarke, J. D.; Dashwood, R. H. Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J. Nutr. 2009, 139, 2393-2396.
    • (2009) J. Nutr , vol.139 , pp. 2393-2396
    • Ho, E.1    Clarke, J.D.2    Dashwood, R.H.3
  • 106
    • 33846838750 scopus 로고    scopus 로고
    • Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
    • Myzak, M. C.; Tong, P.; Dashwood, W. M.; Dashwood, R. H.; Ho, E. Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Exp. Biol. Med. (Maywood) 2007, 232, 227-234.
    • (2007) Exp. Biol. Med. (Maywood) , vol.232 , pp. 227-234
    • Myzak, M.C.1    Tong, P.2    Dashwood, W.M.3    Dashwood, R.H.4    Ho, E.5
  • 107
    • 48349084189 scopus 로고    scopus 로고
    • Dietary agents as histone deacetylase inhibitors: Sulforaphane and structurally related isothiocyanates
    • Dashwood, R. H.; Ho, E. Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates. Nutr. Rev. 2008, 66 Suppl 1, S36-S38.
    • (2008) Nutr. Rev , Issue.66 SUPPL. 1
    • Dashwood, R.H.1    Ho, E.2
  • 108
    • 33744990610 scopus 로고    scopus 로고
    • Dietary agents as histone deacetylase inhibitors
    • Myzak, M. C.; Ho, E.; Dashwood, R. H. Dietary agents as histone deacetylase inhibitors. Mol. Carcinog. 2006, 45, 443-446.
    • (2006) Mol. Carcinog , vol.45 , pp. 443-446
    • Myzak, M.C.1    Ho, E.2    Dashwood, R.H.3
  • 109
    • 65549120719 scopus 로고    scopus 로고
    • Perspectives on the soy-breast cancer relation
    • Messina, M.; Wu, A. H. Perspectives on the soy-breast cancer relation. Am. J. Clin. Nutr. 2009, 89, 1673S-1679S.
    • (2009) Am. J. Clin. Nutr , vol.89
    • Messina, M.1    Wu, A.H.2
  • 110
    • 58849084204 scopus 로고    scopus 로고
    • Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells
    • Bhamre, S.; Sahoo, D.; Tibshirani, R.; Dill, D. L.; Brooks, J. D. Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells. Prostate 2009, 69, 181-190.
    • (2009) Prostate , vol.69 , pp. 181-190
    • Bhamre, S.1    Sahoo, D.2    Tibshirani, R.3    Dill, D.L.4    Brooks, J.D.5
  • 111
    • 63349102182 scopus 로고    scopus 로고
    • Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells
    • Telang, U.; Brazeau, D. A.; Morris, M. E. Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells. Exp. Biol. Med. (Maywood) 2009, 234, 287-295.
    • (2009) Exp. Biol. Med. (Maywood) , vol.234 , pp. 287-295
    • Telang, U.1    Brazeau, D.A.2    Morris, M.E.3
  • 112
    • 4143130097 scopus 로고    scopus 로고
    • A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase
    • Myzak, M. C.; Karplus, P. A.; Chung, F. L.; Dashwood, R. H. A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Res. 2004, 64, 5767-5774.
    • (2004) Cancer Res , vol.64 , pp. 5767-5774
    • Myzak, M.C.1    Karplus, P.A.2    Chung, F.L.3    Dashwood, R.H.4
  • 113
    • 33645825587 scopus 로고    scopus 로고
    • Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice
    • Myzak, M. C.; Dashwood, W. M.; Orner, G. A.; Ho, E.; Dashwood, R. H. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. FASEB J. 2006, 20, 506-508.
    • (2006) FASEB J , vol.20 , pp. 506-508
    • Myzak, M.C.1    Dashwood, W.M.2    Orner, G.A.3    Ho, E.4    Dashwood, R.H.5
  • 114
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • Balasubramanyam, K.; Varier, R. A.; Altaf, M.; Swaminathan, V.; Siddappa, N. B.; Ranga, U.; Kundu, T. K. Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J. Biol. Chem. 2004, 279, 51163-51171.
    • (2004) J. Biol. Chem , vol.279 , pp. 51163-51171
    • Balasubramanyam, K.1    Varier, R.A.2    Altaf, M.3    Swaminathan, V.4    Siddappa, N.B.5    Ranga, U.6    Kundu, T.K.7
  • 115
    • 33646687937 scopus 로고    scopus 로고
    • Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells
    • Kang, S. K.; Cha, S. H.; Jeon, H. G. Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells. Stem Cells Dev. 2006, 15, 165-174.
    • (2006) Stem Cells Dev , vol.15 , pp. 165-174
    • Kang, S.K.1    Cha, S.H.2    Jeon, H.G.3
  • 116
    • 36248957463 scopus 로고    scopus 로고
    • Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells
    • Chen, Y.; Shu, W.; Chen, W.; Wu, Q.; Liu, H.; Cui, G. Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells. Basic Clin. Pharmacol. Toxicol. 2007, 101, 427-433.
    • (2007) Basic Clin. Pharmacol. Toxicol , vol.101 , pp. 427-433
    • Chen, Y.1    Shu, W.2    Chen, W.3    Wu, Q.4    Liu, H.5    Cui, G.6
  • 117
    • 84865642467 scopus 로고    scopus 로고
    • MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis
    • Izzotti, A.; Cartiglia, C.; Steele, V. E.; De Flora, S. MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis. Mutat. Res. 2012, 751, 287-303.
    • (2012) Mutat. Res , vol.751 , pp. 287-303
    • Izzotti, A.1    Cartiglia, C.2    Steele, V.E.3    de Flora, S.4
  • 118
    • 84860127568 scopus 로고    scopus 로고
    • MicroRNAs in cancer management and their modulation by dietary agents
    • Karius, T.; Schnekenburger, M.; Dicato, M.; Diederich, M. MicroRNAs in cancer management and their modulation by dietary agents. Biochem. Pharmacol. 2012, 83, 1591-1601.
    • (2012) Biochem. Pharmacol , vol.83 , pp. 1591-1601
    • Karius, T.1    Schnekenburger, M.2    Dicato, M.3    Diederich, M.4
  • 119
    • 78149342035 scopus 로고    scopus 로고
    • Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway
    • Zhang, J.; Du, Y.; Wu, C.; Ren, X.; Ti, X.; Shi, J.; Zhao, F.; Yin, H. Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway. Oncol. Rep. 2010, 24, 1217-1223.
    • (2010) Oncol. Rep , vol.24 , pp. 1217-1223
    • Zhang, J.1    Du, Y.2    Wu, C.3    Ren, X.4    Ti, X.5    Shi, J.6    Zhao, F.7    Yin, H.8
  • 120
    • 77955589719 scopus 로고    scopus 로고
    • Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway
    • Zhang, J.; Zhang, T.; Ti, X.; Shi, J.; Wu, C.; Ren, X.; Yin, H. Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway. Biochem. Biophys. Res. Commun. 2010, 399, 1-6.
    • (2010) Biochem. Biophys. Res. Commun , vol.399 , pp. 1-6
    • Zhang, J.1    Zhang, T.2    Ti, X.3    Shi, J.4    Wu, C.5    Ren, X.6    Yin, H.7
  • 122
    • 78149275673 scopus 로고    scopus 로고
    • MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60
    • Fix, L. N.; Shah, M.; Efferth, T.; Farwell, M. A.; Zhang, B. MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60. Cancer Genomics Proteomics 2010, 7, 261-277.
    • (2010) Cancer Genomics Proteomics , vol.7 , pp. 261-277
    • Fix, L.N.1    Shah, M.2    Efferth, T.3    Farwell, M.A.4    Zhang, B.5
  • 123
    • 79954572581 scopus 로고    scopus 로고
    • Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer
    • Siddiqui, I. A.; Asim, M.; Hafeez, B. B.; Adhami, V. M.; Tarapore, R. S.; Mukhtar, H. Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer. FASEB J. 2011, 25, 1198-1207.
    • (2011) FASEB J , vol.25 , pp. 1198-1207
    • Siddiqui, I.A.1    Asim, M.2    Hafeez, B.B.3    Adhami, V.M.4    Tarapore, R.S.5    Mukhtar, H.6
  • 124
    • 73349125465 scopus 로고    scopus 로고
    • MicroRNAs in cancer: Small molecules with a huge impact
    • Iorio, M. V.; Croce, C. M. MicroRNAs in cancer: small molecules with a huge impact. J. Clin. Oncol. 2009, 27, 5848-5856.
    • (2009) J. Clin. Oncol , vol.27 , pp. 5848-5856
    • Iorio, M.V.1    Croce, C.M.2
  • 125
    • 77956408743 scopus 로고    scopus 로고
    • 3,3'-Diindolylmethane negatively regulates Cdc25A and induces a G2/M arrest by modulation of microRNA 21 in human breast cancer cells
    • Jin, Y.; Zou, X.; Feng, X. 3,3'-Diindolylmethane negatively regulates Cdc25A and induces a G2/M arrest by modulation of microRNA 21 in human breast cancer cells. Anticancer Drugs 2010, 21, 814-822.
    • (2010) Anticancer Drugs , vol.21 , pp. 814-822
    • Jin, Y.1    Zou, X.2    Feng, X.3
  • 126
    • 77957721534 scopus 로고    scopus 로고
    • Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells
    • Tili, E.; Michaille, J. J.; Alder, H.; Volinia, S.; Delmas, D.; Latruffe, N.; Croce, C. M. Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells. Biochem. Pharmacol. 2010, 80, 2057-2065.
    • (2010) Biochem. Pharmacol , vol.80 , pp. 2057-2065
    • Tili, E.1    Michaille, J.J.2    Alder, H.3    Volinia, S.4    Delmas, D.5    Latruffe, N.6    Croce, C.M.7
  • 129
    • 48349133693 scopus 로고    scopus 로고
    • Evidence for dietary regulation of microRNA expression in cancer cells
    • Davis, C. D.; Ross, S. A. Evidence for dietary regulation of microRNA expression in cancer cells. Nutr. Rev. 2008, 66, 477-482.
    • (2008) Nutr. Rev , vol.66 , pp. 477-482
    • Davis, C.D.1    Ross, S.A.2
  • 130
    • 77952304948 scopus 로고    scopus 로고
    • Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung
    • Izzotti, A.; Larghero, P.; Cartiglia, C.; Longobardi, M.; Pfeffer, U.; Steele, V. E.; De Flora, S. Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung. Carcinogenesis 2010, 31, 894-901.
    • (2010) Carcinogenesis , vol.31 , pp. 894-901
    • Izzotti, A.1    Larghero, P.2    Cartiglia, C.3    Longobardi, M.4    Pfeffer, U.5    Steele, V.E.6    de Flora, S.7
  • 131
    • 79251644886 scopus 로고    scopus 로고
    • The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer
    • Hu, S.; Dong, T. S.; Dalal, S. R.; Wu, F.; Bissonnette, M.; Kwon, J. H.; Chang, E. B. The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer. PLoS One 2011, 6, e16221.
    • (2011) PLoS One , vol.6
    • Hu, S.1    Dong, T.S.2    Dalal, S.R.3    Wu, F.4    Bissonnette, M.5    Kwon, J.H.6    Chang, E.B.7
  • 132
    • 79952380142 scopus 로고    scopus 로고
    • Ginsenoside Rh2 inhibits glioma cell proliferation by targeting microRNA-128
    • Wu, N.; Wu, G. C.; Hu, R.; Li, M.; Feng, H. Ginsenoside Rh2 inhibits glioma cell proliferation by targeting microRNA-128. Acta Pharmacol. Sin. 2011, 32, 345-353.
    • (2011) Acta Pharmacol. Sin , vol.32 , pp. 345-353
    • Wu, N.1    Wu, G.C.2    Hu, R.3    Li, M.4    Feng, H.5
  • 133
    • 84856893266 scopus 로고    scopus 로고
    • Different mutations in three prime repair exonuclease 1 and ribonuclease H2 genes affect clinical features in Aicardi-Goutieres syndrome
    • Izzotti, A.; Longobardi, M.; Cartiglia, C.; Anzuini, F.; Arrigo, P.; Fazzi, E.; Orcesi, S.; Piana, R. L.; Pulliero, A. Different mutations in three prime repair exonuclease 1 and ribonuclease H2 genes affect clinical features in Aicardi-Goutieres syndrome. J. Child Neurol. 2012, 27, 51-60.
    • (2012) J. Child Neurol , vol.27 , pp. 51-60
    • Izzotti, A.1    Longobardi, M.2    Cartiglia, C.3    Anzuini, F.4    Arrigo, P.5    Fazzi, E.6    Orcesi, S.7    Piana, R.L.8    Pulliero, A.9
  • 134
    • 79960572950 scopus 로고    scopus 로고
    • Cancer stem cells and cancer therapy
    • Soltanian, S.; Matin, M. M. Cancer stem cells and cancer therapy. Tumour Biol. 2011, 32, 425-440.
    • (2011) Tumour Biol , vol.32 , pp. 425-440
    • Soltanian, S.1    Matin, M.M.2
  • 135
    • 84863501984 scopus 로고    scopus 로고
    • Identification of cancer stem cells provides novel tumor models for drug discovery
    • Fang, D. D.; Wen, D.; Xu, Y. Identification of cancer stem cells provides novel tumor models for drug discovery. Front Med. 2012, 6, 112-121.
    • (2012) Front Med , vol.6 , pp. 112-121
    • Fang, D.D.1    Wen, D.2    Xu, Y.3
  • 136
    • 84862318675 scopus 로고    scopus 로고
    • Cancer stem cells: Potential target for bioactive food components
    • Kim, Y. S.; Farrar, W.; Colburn, N. H.; Milner, J. A. Cancer stem cells: potential target for bioactive food components. J. Nutr. Biochem. 2012, 23, 691-698.
    • (2012) J. Nutr. Biochem , vol.23 , pp. 691-698
    • Kim, Y.S.1    Farrar, W.2    Colburn, N.H.3    Milner, J.A.4
  • 137
    • 84867690278 scopus 로고    scopus 로고
    • Effects of curcumin on stem-like cells in human esophageal squamous carcinoma cell lines
    • Almanaa, T. N.; Geusz, M. E.; Jamasbi, R. J. Effects of curcumin on stem-like cells in human esophageal squamous carcinoma cell lines. BMC Complement Altern. Med. 2012, 12, 195.
    • (2012) BMC Complement Altern. Med , vol.12 , pp. 195
    • Almanaa, T.N.1    Geusz, M.E.2    Jamasbi, R.J.3
  • 138
    • 77952420903 scopus 로고    scopus 로고
    • Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: Towards targeting of cancer stem cells with phytochemicals
    • Fong, D.; Yeh, A.; Naftalovich, R.; Choi, T. H.; Chan, M. M. Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: towards targeting of cancer stem cells with phytochemicals. Cancer Lett. 2010, 293, 65-72.
    • (2010) Cancer Lett , vol.293 , pp. 65-72
    • Fong, D.1    Yeh, A.2    Naftalovich, R.3    Choi, T.H.4    Chan, M.M.5
  • 139
    • 79952341098 scopus 로고    scopus 로고
    • A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors
    • Lim, K. J.; Bisht, S.; Bar, E. E.; Maitra, A.; Eberhart, C. G. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol. Ther. 2011, 11, 464-473.
    • (2011) Cancer Biol. Ther , vol.11 , pp. 464-473
    • Lim, K.J.1    Bisht, S.2    Bar, E.E.3    Maitra, A.4    Eberhart, C.G.5
  • 141
    • 79955613215 scopus 로고    scopus 로고
    • Difluorinated-curcumin (CDF): A novel curcumin analog is a potent inhibitor of colon cancer stem-like cells
    • Kanwar, S. S.; Yu, Y.; Nautiyal, J.; Patel, B. B.; Padhye, S.; Sarkar, F. H.; Majumdar, A. P. Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cells. Pharm. Res. 2011, 28, 827-838.
    • (2011) Pharm. Res , vol.28 , pp. 827-838
    • Kanwar, S.S.1    Yu, Y.2    Nautiyal, J.3    Patel, B.B.4    Padhye, S.5    Sarkar, F.H.6    Majumdar, A.P.7
  • 142
  • 143
    • 83555172386 scopus 로고    scopus 로고
    • Frequency of cells expressing CD44, a head and neck cancer stem cell marker: Correlation with tumor aggressiveness
    • Joshua, B.; Kaplan, M. J.; Doweck, I.; Pai, R.; Weissman, I. L.; Prince, M. E.; Ailles, L. E. Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness. Head Neck 2012, 34, 42-49.
    • (2012) Head Neck , vol.34 , pp. 42-49
    • Joshua, B.1    Kaplan, M.J.2    Doweck, I.3    Pai, R.4    Weissman, I.L.5    Prince, M.E.6    Ailles, L.E.7
  • 144
    • 56349116715 scopus 로고    scopus 로고
    • Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300
    • Ryu, M. J.; Cho, M.; Song, J. Y.; Yun, Y. S.; Choi, I. W.; Kim, D. E.; Park, B. S.; Oh, S. Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300. Biochem. Biophys. Res. Commun. 2008, 377, 1304-1308.
    • (2008) Biochem. Biophys. Res. Commun , vol.377 , pp. 1304-1308
    • Ryu, M.J.1    Cho, M.2    Song, J.Y.3    Yun, Y.S.4    Choi, I.W.5    Kim, D.E.6    Park, B.S.7    Oh, S.8
  • 145
    • 33646877856 scopus 로고    scopus 로고
    • Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells
    • Wang, Z.; Zhang, Y.; Banerjee, S.; Li, Y.; Sarkar, F. H. Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells. Cancer 2006, 106, 2503-2513.
    • (2006) Cancer , vol.106 , pp. 2503-2513
    • Wang, Z.1    Zhang, Y.2    Banerjee, S.3    Li, Y.4    Sarkar, F.H.5
  • 147
    • 84870058719 scopus 로고    scopus 로고
    • Synergistic anti-cancer mechanisms of curcumin and paclitaxel for growth inhibition of human brain tumor stem cells and LN18 and U138MG cells
    • Hossain, M. M.; Banik, N. L.; Ray, S. K. Synergistic anti-cancer mechanisms of curcumin and paclitaxel for growth inhibition of human brain tumor stem cells and LN18 and U138MG cells. Neurochem. Int. 2012, 61, 1102-1113.
    • (2012) Neurochem. Int , vol.61 , pp. 1102-1113
    • Hossain, M.M.1    Banik, N.L.2    Ray, S.K.3
  • 149
    • 33744961079 scopus 로고    scopus 로고
    • Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1
    • Kim, J.; Zhang, X.; Rieger-Christ, K. M.; Summerhayes, I. C.; Wazer, D. E.; Paulson, K. E.; Yee, A. S. Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1. J. Biol. Chem. 2006, 281, 10865-10875.
    • (2006) J. Biol. Chem , vol.281 , pp. 10865-10875
    • Kim, J.1    Zhang, X.2    Rieger-Christ, K.M.3    Summerhayes, I.C.4    Wazer, D.E.5    Paulson, K.E.6    Yee, A.S.7
  • 150
    • 84860214416 scopus 로고    scopus 로고
    • Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
    • Tang, S. N.; Fu, J.; Nall, D.; Rodova, M.; Shankar, S.; Srivastava, R. K. Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics. Int. J. Cancer 2012, 131, 30-40.
    • (2012) Int. J. Cancer , vol.131 , pp. 30-40
    • Tang, S.N.1    Fu, J.2    Nall, D.3    Rodova, M.4    Shankar, S.5    Srivastava, R.K.6
  • 151
    • 55549148757 scopus 로고    scopus 로고
    • Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells
    • Li, Y.; Wang, Z.; Kong, D.; Li, R.; Sarkar, S. H.; Sarkar, F. H. Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells. J. Biol. Chem. 2008, 283, 27707-27716.
    • (2008) J. Biol. Chem , vol.283 , pp. 27707-27716
    • Li, Y.1    Wang, Z.2    Kong, D.3    Li, R.4    Sarkar, S.H.5    Sarkar, F.H.6
  • 152
    • 60149095682 scopus 로고    scopus 로고
    • Soy isoflavone genistein upregulates epithelial adhesion molecule E-cadherin expression and attenuates beta-catenin signaling in mammary epithelial cells
    • Su, Y.; Simmen, R. C. Soy isoflavone genistein upregulates epithelial adhesion molecule E-cadherin expression and attenuates beta-catenin signaling in mammary epithelial cells. Carcinogenesis 2009, 30, 331-339.
    • (2009) Carcinogenesis , vol.30 , pp. 331-339
    • Su, Y.1    Simmen, R.C.2
  • 153
    • 84861807248 scopus 로고    scopus 로고
    • Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog-Gli1 pathway
    • Zhang, L.; Li, L.; Jiao, M.; Wu, D.; Wu, K.; Li, X.; Zhu, G.; Yang, L.; Wang, X.; Hsieh, J. T.; He, D. Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog-Gli1 pathway. Cancer Lett. 2012, 323, 48-57.
    • (2012) Cancer Lett , vol.323 , pp. 48-57
    • Zhang, L.1    Li, L.2    Jiao, M.3    Wu, D.4    Wu, K.5    Li, X.6    Zhu, G.7    Yang, L.8    Wang, X.9    Hsieh, J.T.10    He, D.11
  • 155
    • 59349120231 scopus 로고    scopus 로고
    • Pharmacological basis for the role of curcumin in chronic diseases: An age-old spice with modern targets
    • Aggarwal, B. B.; Sung, B. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. Trends Pharmacol. Sci. 2009, 30, 85-94.
    • (2009) Trends Pharmacol. Sci , vol.30 , pp. 85-94
    • Aggarwal, B.B.1    Sung, B.2
  • 156
    • 53449091001 scopus 로고    scopus 로고
    • Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: Implications for colon cancer prevention
    • Hope, C.; Planutis, K.; Planutiene, M.; Moyer, M. P.; Johal, K. S.; Woo, J.; Santoso, C.; Hanson, J. A.; Holcombe, R. F. Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: implications for colon cancer prevention. Mol. Nutr. Food Res. 2008, 52(Suppl 1), S52-61.
    • (2008) Mol. Nutr. Food Res , vol.52 , Issue.SUPPL. 1 , pp. 52-61
    • Hope, C.1    Planutis, K.2    Planutiene, M.3    Moyer, M.P.4    Johal, K.S.5    Woo, J.6    Santoso, C.7    Hanson, J.A.8    Holcombe, R.F.9
  • 160
    • 77951723076 scopus 로고    scopus 로고
    • Cucurbitacin: Ancient compound shedding new light on cancer treatment
    • Lee, D. H.; Iwanski, G. B.; Thoennissen, N. H. Cucurbitacin: ancient compound shedding new light on cancer treatment. ScientificWorldJournal, 2010, 10, 413-418.
    • (2010) ScientificWorldJournal , vol.10 , pp. 413-418
    • Lee, D.H.1    Iwanski, G.B.2    Thoennissen, N.H.3
  • 161
    • 0037444373 scopus 로고    scopus 로고
    • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
    • Blaskovich, M. A.; Sun, J.; Cantor, A.; Turkson, J.; Jove, R.; Sebti, S. M. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Res. 2003, 63, 1270-1279.
    • (2003) Cancer Res , vol.63 , pp. 1270-1279
    • Blaskovich, M.A.1    Sun, J.2    Cantor, A.3    Turkson, J.4    Jove, R.5    Sebti, S.M.6
  • 162
    • 78649648154 scopus 로고    scopus 로고
    • Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44(+)ALDH1(+) cells
    • Chen, Y. W.; Chen, K. H.; Huang, P. I.; Chen, Y. C.; Chiou, G. Y.; Lo, W. L.; Tseng, L. M.; Hsu, H. S.; Chang, K. W.; Chiou, S. H. Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44(+)ALDH1(+) cells. Mol. Cancer Ther. 2010, 9, 2879-2892.
    • (2010) Mol. Cancer Ther , vol.9 , pp. 2879-2892
    • Chen, Y.W.1    Chen, K.H.2    Huang, P.I.3    Chen, Y.C.4    Chiou, G.Y.5    Lo, W.L.6    Tseng, L.M.7    Hsu, H.S.8    Chang, K.W.9    Chiou, S.H.10
  • 164
    • 79959622792 scopus 로고    scopus 로고
    • Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells
    • Hsu, H. S.; Huang, P. I.; Chang, Y. L.; Tzao, C.; Chen, Y. W.; Shih, H. C.; Hung, S. C.; Chen, Y. C.; Tseng, L. M.; Chiou, S. H. Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells. Cancer 2011, 117, 2970-2985.
    • (2011) Cancer , vol.117 , pp. 2970-2985
    • Hsu, H.S.1    Huang, P.I.2    Chang, Y.L.3    Tzao, C.4    Chen, Y.W.5    Shih, H.C.6    Hung, S.C.7    Chen, Y.C.8    Tseng, L.M.9    Chiou, S.H.10
  • 165
    • 49649112171 scopus 로고    scopus 로고
    • Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway
    • Tang, F. Y.; Shih, C. J.; Cheng, L. H.; Ho, H. J.; Chen, H. J. Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway. Mol. Nutr. Food Res. 2008, 52, 646-654.
    • (2008) Mol. Nutr. Food Res , vol.52 , pp. 646-654
    • Tang, F.Y.1    Shih, C.J.2    Cheng, L.H.3    Ho, H.J.4    Chen, H.J.5
  • 167
    • 3242687851 scopus 로고    scopus 로고
    • Enhancement by other compounds of the anti-cancer activity of vitamin D(3) and its analogs
    • Danilenko, M.; Studzinski, G. P. Enhancement by other compounds of the anti-cancer activity of vitamin D(3) and its analogs. Exp. Cell Res. 2004, 298, 339-358.
    • (2004) Exp. Cell Res , vol.298 , pp. 339-358
    • Danilenko, M.1    Studzinski, G.P.2
  • 168
    • 84867753586 scopus 로고    scopus 로고
    • Vitamin d metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo
    • Blomberg Jensen, M.; Jorgensen, A.; Nielsen, J. E.; Steinmeyer, A.; Leffers, H.; Juul, A.; Rajpert-De Meyts, E. Vitamin d metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo. Neoplasia 2012, 14, 952-963.
    • (2012) Neoplasia , vol.14 , pp. 952-963
    • Blomberg Jensen, M.1    Jorgensen, A.2    Nielsen, J.E.3    Steinmeyer, A.4    Leffers, H.5    Juul, A.6    Rajpert-Demeyts, E.7
  • 169
    • 84860783872 scopus 로고    scopus 로고
    • Vitamin D3-inducible mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growth
    • Hsiao, W. C.; Sung, S. Y.; Liao, C. H.; Wu, H. C.; Hsieh, C. L. Vitamin D3-inducible mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growth. Mol. Pharm. 2012, 9, 1396-1408.
    • (2012) Mol. Pharm , vol.9 , pp. 1396-1408
    • Hsiao, W.C.1    Sung, S.Y.2    Liao, C.H.3    Wu, H.C.4    Hsieh, C.L.5
  • 171
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
    • Takebe, N.; Harris, P. J.; Warren, R. Q.; Ivy, S. P. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat. Rev. Clin. Oncol. 2011, 8, 97-106.
    • (2011) Nat. Rev. Clin. Oncol , vol.8 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, S.P.4
  • 172
    • 84863252739 scopus 로고    scopus 로고
    • Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells
    • Montales, M. T.; Rahal, O. M.; Kang, J.; Rogers, T. J.; Prior, R. L.; Wu, X.; Simmen, R. C. Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells. Carcinogenesis 2012, 33, 652-660.
    • (2012) Carcinogenesis , vol.33 , pp. 652-660
    • Montales, M.T.1    Rahal, O.M.2    Kang, J.3    Rogers, T.J.4    Prior, R.L.5    Wu, X.6    Simmen, R.C.7
  • 173
    • 64049084289 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis and increased radiosensitivity in CD133-positive cells derived from atypical teratoid/rhabdoid tumor
    • Kao, C. L.; Huang, P. I.; Tsai, P. H.; Tsai, M. L.; Lo, J. F.; Lee, Y. Y.; Chen, Y. J.; Chen, Y. W.; Chiou, S. H. Resveratrol-induced apoptosis and increased radiosensitivity in CD133-positive cells derived from atypical teratoid/rhabdoid tumor. Int. J. Radiat. Oncol. Biol. Phys. 2009, 74, 219-228.
    • (2009) Int. J. Radiat. Oncol. Biol. Phys , vol.74 , pp. 219-228
    • Kao, C.L.1    Huang, P.I.2    Tsai, P.H.3    Tsai, M.L.4    Lo, J.F.5    Lee, Y.Y.6    Chen, Y.J.7    Chen, Y.W.8    Chiou, S.H.9


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