Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung

Carcinogenesis

Volumn 31, Issue 5, 2010, Pages 894-901

  Izzotti, Alberto ^a   Larghero, Patrizia ^a   Cartiglia, Cristina ^a   Longobardi, Mariagrazia ^a   Pfeffer, Ulrich ^b,c   Steele, Vernon E ^a   De Flora, Silvio ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; DNA; MICRORNA; PHENETHYL ISOTHIOCYANATE; ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CELL STRESS; CIGARETTE SMOKING; CONTROLLED STUDY; DIET THERAPY; DNA DAMAGE; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; EXPERIMENTAL MOUSE; FEMALE; INFLAMMATION; LIVER; LIVER TOXICITY; LUNG; MALE; MICROARRAY ANALYSIS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHAM PROCEDURE; WEANING; ANIMAL; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM; SMOKE; TOBACCO;

ANIMALS; ANTICARCINOGENIC AGENTS; BUDESONIDE; FEMALE; GENE EXPRESSION REGULATION; ISOTHIOCYANATES; LIVER; LUNG; MICE; MICRORNAS; SMOKE; TOBACCO;

EID: 77952304948     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq037     Document Type: Article

References (33)

1. Couzin, J. (2008) MicroRNAs make big impression in disease after disease. Science, 319, 1782-1784.
2. Meltzer, P.S. (2005) Cancer genomics: small RNAs with big impacts. Nature, 435, 745-746.
3. Girard, M. et al. (2008) MiR-122, a paradigm for the role of microRNAs in the liver. J. Hepatol., 48, 648-656.
4. Calin, G.A. et al. (2006) MicroRNA-cancer connection: the beginning of a new tale. Cancer Res., 66, 7390-7394.
5. Izzotti, A. et al. (2009) Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J., 23, 806-812.
6. Izzotti, A. et al. (2005) Modulation of multigene expression and proteome profiles by chemopreventive agents. Mutat. Res., 591, 212-223.
7. Izzotti, A. et al. (2005) Chemoprevention of genome, transcriptome, and proteome alterations induced by cigarette smoke in rat lung. Eur. J. Cancer, 41, 1864-1874.
8. Izzotti, A. et al. (2009) MicroRNA expression in mouse lung, as related to age and exposure to cigarette smoke and light. FASEB J., 23, 3243-3250.
9. Schembri, F. et al. (2009) MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc. Natl Acad. Sci. USA, 106, 2319-2324.
10. Liu, X. et al. (2009) Uncovering growth-suppressive microRNAs in lung cancer. Clin. Cancer Res., 15, 1177-1183.
11. Melkamu, T. et al. (2010) Alteration of microRNA expression in vinyl-carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol. Carcinogenesis, 31, 252-258.
12. Izzotti, A. et al. (2010) Chemoprevention of cigarette smoke-induced alterations of microRNA expression in rat lung. Cancer Prev. Res., 3, 62-72.
13. Izzotti, A. et al. (1998) DNA alterations in rat organs following chronic exposure to cigarette smoke and/or ethanol ingestion. FASEB J., 12, 753-758.
14. IARC. (2004) IARC Monographs on the Evaluation of Carcinogenic Risk to Humans. Tobacco Smoke and Involuntary Smoking, Vol. 83, IARC, Lyon.
15. Wattenberg, L.W. et al. (1997) Chemoprevention of pulmonary carcinogenesis by aerosolized budesonide in female A/J mice. Cancer Res., 57, 5489-5492.
16. Wattenberg, L.W. et al. (2000) Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol. Carcinogenesis, 21, 179-182.
17. Estensen, R.D. et al. (2004) Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice. Carcinogenesis, 25, 197-201.
18. Wang, Y. et al. (2003) Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice. Cancer Res., 63, 4389-4395.
19. Balansky, R. et al. (2006) Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine. Proc. Natl Acad. Sci. USA, 103, 7823-7828.
20. Pereira, M.A. et al. (2002) Prevention of mouse lung tumors by budesonide and its modulation of biomarkers. Carcinogenesis, 23, 1185-1189.
21. Yao, R. et al. (2004) Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions. Oncogene, 23, 7746-7752.
22. Hecht, S.S. (1999) Chemoprevention of cancer by isothiocyanates, modifiers of carcinogen metabolism. J. Nutr., 129, 768S-774S.
23. Stoner, G.D. et al. (1997) Isothiocyanates and plant polyphenols as inhibitors of lung and esophageal cancer. Cancer Lett., 114, 113-119.
24. Conaway, C.C. et al. (2005) Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. Cancer Res., 65, 8548-8557.
25. Ye, B. et al. (2007) Induction of lung lesions in Wistar rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by aspirin and phenethyl isothiocyanate. BMC Cancer, 7, 90.
26. Izzotti, A. et al. (2001) Modulation of biomarkers by chemopreventive agents in smoke-exposed rats. Cancer Res., 61, 2472-2479.
27. D'Agostini, F. et al. (2009) Modulation by phenethyl isothiocyanate and budesonide of molecular and histopathological alterations induced by environmental cigarette smoke in mice. Cancer Prev. Res., 2, 546-556.
28. D'Agostini, F. et al. (2008) Preneoplastic and neoplastic lesions in the lung, liver, and urinary tract of mice exposed to environmental cigarette smoke and UV light since birth. Int. J. Cancer, 123, 2497-2502.
29. Balansky, R. et al. (2007) Potent carcinogenicity of cigarette smoke in mice exposed early in life. Carcinogenesis, 28, 2236-2243.
30. Edsbäcker, S. et al. (2004) Pharmacokinetics of budesonide (Entocort EC) capsules for Crohn's disease. Clin. Pharmacokinet., 43, 803-821.
31. Ryrfeldt, A. et al. (1992) Liver tumors in male rats following treatment with glucocorticosteroids. Toxicol. Pathol., 20, 115-117.
32. Conaway, C.C. et al. (2002) Isothiocyanates as cancer chemopreventive agents: their biological activities and metabolism in rodents and humans. Curr. Drug Metab., 3, 233-255.
33. Kassie, F. et al. (2000) Genotoxic effects of allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC). Chem. Biol. Interact., 127, 163- 180.