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Volumn 1, Issue 3-4, 2010, Pages 101-116

Epigenetic targets of bioactive dietary components for cancer prevention and therapy

Author keywords

Bioactive component.; Cancer.; Dietary polyphenol.; DNA methylation.; Epigenetic.; Histone modifications

Indexed keywords

APIGENIN; CURCUMIN; DNA METHYLTRANSFERASE; EPIGALLOCATECHIN GALLATE; GENISTEIN; LYCOPENE; POLYPHENOL; POLYPHENON E; RESVERATROL; SILYMARIN; SULFORAPHANE; THIOL;

EID: 79952364603     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1007/s13148-010-0011-5     Document Type: Review
Times cited : (216)

References (161)
  • 1
    • 25144440127 scopus 로고    scopus 로고
    • Rational development of histone deacetylase inhibitors as anticancer agents: A review
    • DOI 10.1124/mol.105.014167
    • Acharya M, Sparreboom A, Venitz J, Figg W (2005) Rational development of histone deacetylase inhibitors as anticancer agents: A review. Mol Pharmacol 68:917-932 (Pubitemid 41345783)
    • (2005) Molecular Pharmacology , vol.68 , Issue.4 , pp. 917-932
    • Acharya, M.R.1    Sparreboom, A.2    Venitz, J.3    Figg, W.D.4
  • 2
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal B, Shishodia S (2006) Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 71:1397-1421
    • (2006) Biochem Pharmacol , vol.71 , pp. 1397-1421
    • Aggarwal, B.1    Shishodia, S.2
  • 3
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: Preclinical and clinical studies
    • Aggarwal B, Kumar A, Bharti A (2003) Anticancer potential of curcumin: Preclinical and clinical studies. Anticancer Res 23:363-398 (Pubitemid 36361976)
    • (2003) Anticancer Research , vol.23 , Issue.1 , pp. 363-398
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 4
    • 0031444312 scopus 로고    scopus 로고
    • Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
    • Ahmad N, Feyes D, Nieminen A, Agarwal R, Mukhtar H (1997) Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst 89:1881-1886 (Pubitemid 28009824)
    • (1997) Journal of the National Cancer Institute , vol.89 , Issue.24 , pp. 1881-1886
    • Ahmad, N.1    Feyes, D.K.2    Nieminen, A.-L.3    Agarwal, R.4    Mukhtar, H.5
  • 5
    • 67349128956 scopus 로고    scopus 로고
    • Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms
    • Athar M, Back J, Kopelovich L, Bickers D, Kim A (2009) Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms. Arch Biochem Biophys 486:95-102
    • (2009) Arch Biochem Biophys , vol.486 , pp. 95-102
    • Athar, M.1    Back, J.2    Kopelovich, L.3    Bickers, D.4    Kim, A.5
  • 6
    • 0346888660 scopus 로고    scopus 로고
    • Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes
    • DOI 10.1093/carcin/bgg157
    • Bacon JR, Williamson G, Garner RC, Lappin G, Langouet S, Bao Y (2003) Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes. Carcinogenesis 24:1903-1911 (Pubitemid 38008530)
    • (2003) Carcinogenesis , vol.24 , Issue.12 , pp. 1903-1911
    • Bacon, J.R.1    Williamson, G.2    Garner, R.C.3    Lappin, G.4    Langouet, S.5    Bao, Y.6
  • 7
    • 77950907191 scopus 로고    scopus 로고
    • The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3- gallatedependent suppression of skin cancer cell survival
    • Balasubramanian S, Adhikary G, Eckert RL (2010) The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallatedependent suppression of skin cancer cell survival. Carcinogenesis 31:496-503
    • (2010) Carcinogenesis , vol.31 , pp. 496-503
    • Balasubramanian, S.1    Adhikary, G.2    Eckert, R.L.3
  • 8
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • DOI 10.1074/jbc.M409024200
    • Balasubramanyam K, Varier R, Altaf M, Swaminathan V, Siddappa N, Ranga U, Kundu T (2004) Curcumin, a novel p300/CREBbinding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem 279:51163-51171 (Pubitemid 40017859)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.49 , pp. 51163-51171
    • Balasubramanyam, K.1    Varier, R.A.2    Altaf, M.3    Swaminathan, V.4    Siddappa, N.B.5    Ranga, U.6    Kundu, T.K.7
  • 9
    • 0035169663 scopus 로고    scopus 로고
    • Methyl-CpG-binding proteins: Targeting specific gene repression
    • DOI 10.1046/j.1432-1327.2001.01869.x
    • Ballestar E, Wolffe A (2001) Methyl-CpG-binding proteins. Targeting specific gene repression. Eur J Biochem 268:1-6 (Pubitemid 32052241)
    • (2001) European Journal of Biochemistry , vol.268 , Issue.1 , pp. 1-6
    • Ballestar, E.1    Wolffe, A.P.2
  • 10
    • 0028815434 scopus 로고
    • Effect of genistein on in vitro and in vivo models of cancer
    • Barnes S (1995) Effect of genistein on in vitro and in vivo models of cancer. J Nutr 125:777S-783S
    • (1995) J Nutr , vol.125
    • Barnes, S.1
  • 12
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T (2000) The DNA methyltransferases of mammals. Hum Mol Genet 9:2395-2402
    • (2000) Hum Mol Genet , vol.9 , pp. 2395-2402
    • Bestor, T.1
  • 13
    • 58849084204 scopus 로고    scopus 로고
    • Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells
    • Bhamre S, Sahoo D, Tibshirani R, Dill D, Brooks J (2009) Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells. Prostate 69:181-190
    • (2009) Prostate , vol.69 , pp. 181-190
    • Bhamre, S.1    Sahoo, D.2    Tibshirani, R.3    Dill, D.4    Brooks, J.5
  • 14
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • DOI 10.1038/nature05913, PII NATURE05913
    • Bird A (2007) Perceptions of epigenetics. Nature 447:396-398 (Pubitemid 46816744)
    • (2007) Nature , vol.447 , Issue.7143 , pp. 396-398
    • Bird, A.1
  • 15
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials
    • Bishayee A (2009) Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials. Cancer Prev Res (Phila Pa) 2:409-418
    • (2009) Cancer Prev Res (Phila Pa) , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 17
    • 68949113934 scopus 로고    scopus 로고
    • SirT1- null mice develop tumors at normal rates but are poorly protected by resveratrol
    • Boily G, He XH, Pearce B, Jardine K, McBurney MW (2009) SirT1- null mice develop tumors at normal rates but are poorly protected by resveratrol. Oncogene 28:2882-2893
    • (2009) Oncogene , vol.28 , pp. 2882-2893
    • Boily, G.1    He, X.H.2    Pearce, B.3    Jardine, K.4    McBurney, M.W.5
  • 18
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activities of histone deacetylase inhibitors
    • DOI 10.1038/nrd2133, PII NRD2133
    • Bolden J, Peart M, Johnstone R (2006) Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov 5:769-784 (Pubitemid 44348499)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.9 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3
  • 21
    • 36248957463 scopus 로고    scopus 로고
    • Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells
    • DOI 10.1111/j.1742-7843.2007.00142.x
    • Chen Y, Shu W, Chen W, Wu Q, Liu H, Cui G (2007) Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells. Basic Clin Pharmacol Toxicol 101:427-433 (Pubitemid 350135350)
    • (2007) Basic and Clinical Pharmacology and Toxicology , vol.101 , Issue.6 , pp. 427-433
    • Chen, Y.1    Shu, W.2    Chen, W.3    Wu, Q.4    Liu, H.5    Cui, G.6
  • 22
    • 77449106593 scopus 로고    scopus 로고
    • Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention
    • Cheung KL, Kong AN (2010) Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention. AAPS J 12:87-97
    • (2010) AAPS J , vol.12 , pp. 87-97
    • Cheung, K.L.1    Kong, A.N.2
  • 23
    • 67651182607 scopus 로고    scopus 로고
    • Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB
    • Chiu J, Khan Z, Farhangkhoee H, Chakrabarti S (2009) Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB. Nutrition 25:964-972
    • (2009) Nutrition , vol.25 , pp. 964-972
    • Chiu, J.1    Khan, Z.2    Farhangkhoee, H.3    Chakrabarti, S.4
  • 25
    • 77953126448 scopus 로고    scopus 로고
    • Molecular targets of epigenetic regulation and effectors of environmental influences
    • Choudhuri S, Cui Y, Klaassen C (2010) Molecular targets of epigenetic regulation and effectors of environmental influences. Toxicol Appl Pharmacol 245:378-393
    • (2010) Toxicol Appl Pharmacol , vol.245 , pp. 378-393
    • Choudhuri, S.1    Cui, Y.2    Klaassen, C.3
  • 26
    • 70349929035 scopus 로고    scopus 로고
    • Sulforaphane induces G2-M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma
    • Chu WF, Wu DM, Liu W, Wu LJ, Li DZ, Xu DY, Wang XF (2009) Sulforaphane induces G2-M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma. Oral Oncol 45:998-1004
    • (2009) Oral Oncol , vol.45 , pp. 998-1004
    • Chu, W.F.1    Wu, D.M.2    Liu, W.3    Wu, L.J.4    Li, D.Z.5    Xu, D.Y.6    Wang, X.F.7
  • 28
    • 70349320158 scopus 로고    scopus 로고
    • Causes and consequences of microRNA dysregulation in cancer
    • Croce C (2009) Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 10:704-714
    • (2009) Nat Rev Genet , vol.10 , pp. 704-714
    • Croce, C.1
  • 29
    • 34447546839 scopus 로고    scopus 로고
    • PfGCN5-mediated histone H3 acetylation plays a key role in gene expression in Plasmodium falciparum
    • DOI 10.1128/EC.00062-07
    • Cui L, Miao J, Furuya T, Li X, Su XZ (2007) PfGCN5-mediated histone H3 acetylation plays a key role in gene expression in Plasmodium falciparum. Eukaryot Cell 6:1219-1227 (Pubitemid 47077173)
    • (2007) Eukaryotic Cell , vol.6 , Issue.7 , pp. 1219-1227
    • Cui, L.1    Miao, J.2    Furuya, T.3    Li, X.4    Su, X.-Z.5    Cui, L.6
  • 30
    • 77149156308 scopus 로고    scopus 로고
    • The role of histone modifications and variants in regulating gene expression in breast cancer
    • Dalvai M, Bystricky K (2010) The role of histone modifications and variants in regulating gene expression in breast cancer. J Mammary Gland Biol Neoplasia 15:19-33
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 19-33
    • Dalvai, M.1    Bystricky, K.2
  • 31
    • 34548456881 scopus 로고    scopus 로고
    • Dietary histone deacetylase inhibitors: From cells to mice to man
    • DOI 10.1016/j.semcancer.2007.04.001, PII S1044579X07000247
    • Dashwood RH, Ho E (2007) Dietary histone deacetylase inhibitors: From cells to mice to man. Semin Cancer Biol 17:363-369 (Pubitemid 47369168)
    • (2007) Seminars in Cancer Biology , vol.17 , Issue.5 , pp. 363-369
    • Dashwood, R.H.1    Ho, E.2
  • 32
    • 48349084189 scopus 로고    scopus 로고
    • Dietary agents as histone deacetylase inhibitors: Sulforaphane and structurally related isothiocyanates
    • Dashwood R, Ho E (2008) Dietary agents as histone deacetylase inhibitors: Sulforaphane and structurally related isothiocyanates. Nutr Rev 66(Suppl 1):S36-S38
    • (2008) Nutr Rev , vol.66 , Issue.SUPPL. 1
    • Dashwood, R.1    Ho, E.2
  • 33
    • 33947515716 scopus 로고    scopus 로고
    • Dietary components impact histone modifications and cancer risk
    • DOI 10.1111/j.1753-4887.2007.tb00285.x
    • Davis CD, Ross SA (2007) Dietary components impact histone modifications and cancer risk. Nutr Rev 65:88-94 (Pubitemid 351804383)
    • (2007) Nutrition Reviews , vol.65 , Issue.2 , pp. 88-94
    • Davis, C.D.1    Ross, S.A.2
  • 37
    • 33845211776 scopus 로고    scopus 로고
    • Epigenetic aberrations and cancer
    • Ducasse M, Brown M (2006) Epigenetic aberrations and cancer. Mol Cancer 5:60
    • (2006) Mol Cancer , vol.5 , pp. 60
    • Ducasse, M.1    Brown, M.2
  • 39
    • 67649305191 scopus 로고    scopus 로고
    • Epigenetics in cancer: Targeting chromatin modifications
    • Ellis L, Atadja P, Johnstone R (2009) Epigenetics in cancer: Targeting chromatin modifications. Mol Cancer Ther 8:1409-1420
    • (2009) Mol Cancer Ther , vol.8 , pp. 1409-1420
    • Ellis, L.1    Atadja, P.2    Johnstone, R.3
  • 40
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • DOI 10.1038/nrg2005, PII NRG2005
    • Esteller M (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8:286-298 (Pubitemid 46439286)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 41
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M (2008) Epigenetics in cancer. N Engl J Med 358:1148-1159
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 43
    • 0345275879 scopus 로고    scopus 로고
    • Tea Polyphenol (-)-Epigallocatechin-3-Gallate Inhibits DNA Methyltransferase and Reactivates Methylation-Silenced Genes in Cancer Cell Lines
    • Fang M, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W, Yang C (2003) Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 63:7563-7570 (Pubitemid 37466673)
    • (2003) Cancer Research , vol.63 , Issue.22 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5    Lu, H.6    Welsh, W.7    Yang, C.S.8
  • 44
    • 26444451123 scopus 로고    scopus 로고
    • INK4a, RARβ, and MGMT genes by genistein and other isoflavones from soy
    • DOI 10.1158/1078-0432.CCR-05-0406
    • Fang M, Chen D, Sun Y, Jin Z, Christman J, Yang C (2005) Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 11:7033-7041 (Pubitemid 41428763)
    • (2005) Clinical Cancer Research , vol.11 , Issue.19 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 45
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang M, Chen D, Yang C (2007) Dietary polyphenols may affect DNA methylation. J Nutr 137:223S-228S (Pubitemid 46052885)
    • (2007) Journal of Nutrition , vol.137 , Issue.1
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 46
    • 3242664189 scopus 로고    scopus 로고
    • Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate
    • DOI 10.1158/1078-0432.CCR-03-0672
    • Fassina G, Venè R, Morini M, Minghelli S, Benelli R, Noonan D, Albini A (2004) Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate. Clin Cancer Res 10:4865-4873 (Pubitemid 38955541)
    • (2004) Clinical Cancer Research , vol.10 , Issue.14 , pp. 4865-4873
    • Fassina, G.1    Vene, R.2    Morini, M.3    Minghelli, S.4    Benelli, R.5    Noonan, D.M.6    Albini, A.7
  • 48
    • 78349269863 scopus 로고    scopus 로고
    • Development of curcumin as an epigenetic agent
    • (in press)
    • Fu S, Kurzrock R (2010) Development of curcumin as an epigenetic agent. Cancer (in press)
    • (2010) Cancer
    • Fu, S.1    Kurzrock, R.2
  • 49
    • 74849127193 scopus 로고    scopus 로고
    • Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery
    • Ganesan A, Nolan L, Crabb SJ, Packham G (2009) Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery. Curr Cancer Drug Targets 9:963-981
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 963-981
    • Ganesan, A.1    Nolan, L.2    Crabb, S.J.3    Packham, G.4
  • 52
    • 0026771060 scopus 로고
    • Green tea composition, consumption, and polyphenol chemistry
    • Graham H (1992) Green tea composition, consumption, and polyphenol chemistry. Prev Med 21:334-350
    • (1992) Prev Med , vol.21 , pp. 334-350
    • Graham, H.1
  • 53
    • 36549056015 scopus 로고    scopus 로고
    • Epigenetic changes in cancer
    • DOI 10.1111/j.1600-0463.2007.apm-636.xml.x
    • Grønbaek K, Hother C, Jones P (2007) Epigenetic changes in cancer. APMIS 115:1039-1059 (Pubitemid 350179474)
    • (2007) APMIS , vol.115 , Issue.10 , pp. 1039-1059
    • Gronbaek, K.1    Hother, C.2    Jones, P.A.3
  • 54
    • 31344441221 scopus 로고    scopus 로고
    • Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis
    • Gu Y, Zhu CF, Iwamoto H, Chen JS (2005) Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis. World J Gastroenterol 11:6512-6517 (Pubitemid 43136890)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.41 , pp. 6512-6517
    • Gu, Y.1    Zhu, C.-F.2    Iwamoto, H.3    Chen, J.-S.4
  • 55
    • 64849110824 scopus 로고    scopus 로고
    • EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression
    • Gu B, Ding Q, Xia G, Fang Z (2009) EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression. Oncol Rep 21:635-640
    • (2009) Oncol Rep , vol.21 , pp. 635-640
    • Gu, B.1    Ding, Q.2    Xia, G.3    Fang, Z.4
  • 56
    • 52949108784 scopus 로고    scopus 로고
    • Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
    • Guerrero-Bosagna C, Sabat P, Valdovinos F, Valladares L, Clark S (2008) Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC Physiol 8:17
    • (2008) BMC Physiol , vol.8 , pp. 17
    • Guerrero-Bosagna, C.1    Sabat, P.2    Valdovinos, F.3    Valladares, L.4    Clark, S.5
  • 57
    • 55949134303 scopus 로고    scopus 로고
    • DNA methylomes, histone codes and miRNAs: Tying it all together
    • Guil S, Esteller M (2009) DNA methylomes, histone codes and miRNAs: Tying it all together. Int J Biochem Cell Biol 41:87-95
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 87-95
    • Guil, S.1    Esteller, M.2
  • 58
    • 8444247426 scopus 로고    scopus 로고
    • Unusual distribution of DNA methylation within the hTERT CpG island in tissues and cell lines
    • DOI 10.1016/j.bbrc.2004.10.137, PII S0006291X04024829
    • Guilleret I, Benhattar J (2004) Unusual distribution of DNA methylation within the hTERT CpG island in tissues and cell lines. Biochem Biophys Res Commun 325:1037-1043 (Pubitemid 39487975)
    • (2004) Biochemical and Biophysical Research Communications , vol.325 , Issue.3 , pp. 1037-1043
    • Guilleret, I.1    Benhattar, J.2
  • 59
    • 0024003456 scopus 로고
    • A direct link between core histone acetylation and transcriptionally active chromatin
    • Hebbes T, Thorne A, Crane-Robinson C (1988) A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J 7:1395-1402
    • (1988) EMBO J , vol.7 , pp. 1395-1402
    • Hebbes, T.1    Thorne, A.2    Crane-Robinson, C.3
  • 61
    • 33847613305 scopus 로고    scopus 로고
    • Epigenetics and cancer: Towards an evaluation of the impact of environmental and dietary factors
    • DOI 10.1093/mutage/gel068
    • Herceg Z (2007) Epigenetics and cancer: Towards an evaluation of the impact of environmental and dietary factors.Mutagenesis 22:91-103 (Pubitemid 46364521)
    • (2007) Mutagenesis , vol.22 , Issue.2 , pp. 91-103
    • Herceg, Z.1
  • 62
    • 34250757157 scopus 로고    scopus 로고
    • Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line
    • DOI 10.1158/1535-7163.MCT-06-0807
    • Herman-Antosiewicz A, Xiao H, Lew KL, Singh SV (2007) Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line. Mol Cancer Ther 6:1673-1681 (Pubitemid 46954034)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.5 , pp. 1673-1681
    • Herman-Antosiewicz, A.1    Xiao, H.2    Lew, K.L.3    Singh, S.V.4
  • 63
    • 34047136753 scopus 로고    scopus 로고
    • Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
    • DOI 10.1016/j.phrs.2007.01.009, PII S1043661807000321, Nutritional Pharmacology
    • Higdon JV, Delage B, Williams DE, Dashwood RH (2007) Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis. Pharmacol Res 55:224-236 (Pubitemid 46518152)
    • (2007) Pharmacological Research , vol.55 , Issue.3 , pp. 224-236
    • Higdon, J.V.1    Delage, B.2    Williams, D.E.3    Dashwood, R.H.4
  • 64
    • 72249122960 scopus 로고    scopus 로고
    • Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention
    • Ho E, Clarke JD, Dashwood RH (2009) Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr 139:2393-2396
    • (2009) J Nutr , vol.139 , pp. 2393-2396
    • Ho, E.1    Clarke, J.D.2    Dashwood, R.H.3
  • 65
    • 0025116236 scopus 로고
    • Mechanisms for the control of gene activity during development
    • Holliday R (1990) Mechanisms for the control of gene activity during development. Biol Rev Camb Philos Soc 65:431-471
    • (1990) Biol Rev Camb Philos Soc , vol.65 , pp. 431-471
    • Holliday, R.1
  • 67
    • 75449099982 scopus 로고    scopus 로고
    • Proteasome inhibition in human breast cancer cells with high catechol-Omethyltransferase activity by green tea polyphenol EGCG analogs
    • Huo C, Yang H, Cui QC, Dou QP, Chan TH (2010) Proteasome inhibition in human breast cancer cells with high catechol-Omethyltransferase activity by green tea polyphenol EGCG analogs. Bioorg Med Chem 18:1252-1258
    • (2010) Bioorg Med Chem , vol.18 , pp. 1252-1258
    • Huo, C.1    Yang, H.2    Cui, Q.C.3    Dou, Q.P.4    Chan, T.H.5
  • 68
    • 59249103688 scopus 로고    scopus 로고
    • Cancer prevention: Epigenetics steps up to the plate
    • Issa JP (2008) Cancer prevention: Epigenetics steps up to the plate. Cancer Prev Res (Phila Pa) 1:219-222
    • (2008) Cancer Prev Res (Phila Pa) , vol.1 , pp. 219-222
    • Issa, J.P.1
  • 71
    • 33646687937 scopus 로고    scopus 로고
    • Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells
    • Kang SK, Cha SH, Jeon HG (2006) Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells. Stem Cells Dev 15:165-174
    • (2006) Stem Cells Dev , vol.15 , pp. 165-174
    • Kang, S.K.1    Cha, S.H.2    Jeon, H.G.3
  • 72
    • 77955722773 scopus 로고    scopus 로고
    • Computational modeling of the potential interactions of the proteasome beta5 subunit and catechol-O-methyltransferaseresistant EGCG analogs
    • Kanwar J, Mohammad I, Yang H, Huo C, Chan TH, Dou QP (2010) Computational modeling of the potential interactions of the proteasome beta5 subunit and catechol-O-methyltransferaseresistant EGCG analogs. Int J Mol Med 26:209-215
    • (2010) Int J Mol Med , vol.26 , pp. 209-215
    • Kanwar, J.1    Mohammad, I.2    Yang, H.3    Huo, C.4    Chan, T.H.5    Dou, Q.P.6
  • 73
    • 49549087270 scopus 로고    scopus 로고
    • Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells
    • Kato K, Long NK, Makita H, Toida M, Yamashita T, Hatakeyama D, Hara A, Mori H, Shibata T (2008) Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells. Br J Cancer 99:647-654
    • (2008) Br J Cancer , vol.99 , pp. 647-654
    • Kato, K.1    Long, N.K.2    Makita, H.3    Toida, M.4    Yamashita, T.5    Hatakeyama, D.6    Hara, A.7    Mori, H.8    Shibata, T.9
  • 74
    • 69949157311 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: Implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway
    • Keum YS, Khor TO, Lin W, Shen G, Kwon KH, Barve A, Li W, Kong AN (2009) Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: Implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway. Pharm Res 26:2324-2331
    • (2009) Pharm Res , vol.26 , pp. 2324-2331
    • Keum, Y.S.1    Khor, T.O.2    Lin, W.3    Shen, G.4    Kwon, K.H.5    Barve, A.6    Li, W.7    Kong, A.N.8
  • 76
    • 0038544192 scopus 로고    scopus 로고
    • Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents
    • Kim D, Kim M, Kwon H (2003) Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents. J Biochem Mol Biol 36:110-119 (Pubitemid 36836262)
    • (2003) Journal of Biochemistry and Molecular Biology , vol.36 , Issue.1 , pp. 110-119
    • Kim, D.H.1    Kim, M.2    Kwon, H.J.3
  • 77
  • 78
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin Modifications and Their Function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • Kouzarides T (2007) Chromatin modifications and their function. Cell 128:693-705 (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 81
    • 17444417521 scopus 로고    scopus 로고
    • Cancer epigenetics
    • DOI 10.1093/hmg/ddi113
    • Laird P (2005) Cancer epigenetics. Hum Mol Genet 14(Spec No 1): R65-R76 (Pubitemid 40542622)
    • (2005) Human Molecular Genetics , vol.14 , Issue.SPEC. ISS. 1
    • Laird, P.W.1
  • 82
    • 34249299083 scopus 로고    scopus 로고
    • A novel prodrug of the green tea polyphenol (-)-epigallocatechin-3- gallate as a potential anticancer agent
    • DOI 10.1158/0008-5472.CAN-06-4699
    • Landis-Piwowar KR, Huo C, Chen D, Milacic V, Shi G, Chan TH, Dou QP (2007) A novel prodrug of the green tea polyphenol (-)- epigallocatechin-3- gallate as a potential anticancer agent. Cancer Res 67:4303-4310 (Pubitemid 46815078)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4303-4310
    • Landis-Piwowar, K.R.1    Huo, C.2    Chen, D.3    Milacic, V.4    Shi, G.5    Tak, H.C.6    Dou, Q.P.7
  • 83
    • 54849416116 scopus 로고    scopus 로고
    • Relationship between the methylation status of dietary flavonoids and their growthinhibitory and apoptosis-inducing activities in human cancer cells
    • Landis-Piwowar KR, Milacic V, Dou QP (2008) Relationship between the methylation status of dietary flavonoids and their growthinhibitory and apoptosis-inducing activities in human cancer cells. J Cell Biochem 105:514-523
    • (2008) J Cell Biochem , vol.105 , pp. 514-523
    • Landis-Piwowar, K.R.1    Milacic, V.2    Dou, Q.P.3
  • 84
    • 77954358651 scopus 로고    scopus 로고
    • Inhibition of catechol-Omicron-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG
    • Landis-Piwowar K, Chen D, Chan TH, Dou QP (2010) Inhibition of catechol-Omicron-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG. Oncol Rep 24:563-569
    • (2010) Oncol Rep , vol.24 , pp. 563-569
    • Landis-Piwowar, K.1    Chen, D.2    Chan, T.H.3    Dou, Q.P.4
  • 85
    • 0035876964 scopus 로고    scopus 로고
    • Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate
    • DOI 10.1002/ijc.1277
    • Lea M, Randolph V, Lee J, desBordes C (2001) Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. Int J Cancer 92:784-789 (Pubitemid 32467365)
    • (2001) International Journal of Cancer , vol.92 , Issue.6 , pp. 784-789
    • Lea, M.A.1    Randolph, V.M.2    Lee, J.E.3    DesBordes, C.4
  • 86
    • 31544441371 scopus 로고    scopus 로고
    • Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols
    • DOI 10.1093/carcin/bgi206
    • Lee W, Zhu B (2006) Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis 27:269-277 (Pubitemid 43159879)
    • (2006) Carcinogenesis , vol.27 , Issue.2 , pp. 269-277
    • Lee, W.J.1    Zhu, B.T.2
  • 88
    • 25144507259 scopus 로고    scopus 로고
    • Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
    • DOI 10.1124/mol.104.008367
    • Lee W, Shim J, Zhu B (2005) Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol Pharmacol 68:1018-1030 (Pubitemid 41345793)
    • (2005) Molecular Pharmacology , vol.68 , Issue.4 , pp. 1018-1030
    • Won, J.L.1    Shim, J.-Y.2    Zhu, B.T.3
  • 89
    • 77955621544 scopus 로고    scopus 로고
    • Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components
    • Li Y, Tollefsbol T (2010) Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Curr Med Chem 17:2141-2151
    • (2010) Curr Med Chem , vol.17 , pp. 2141-2151
    • Li, Y.1    Tollefsbol, T.2
  • 90
    • 34250667940 scopus 로고    scopus 로고
    • Activation of the SIRT1 pathway and modulation of the cell cycle were involved in silymarin's protection against UV-induced A375-S2 cell apoptosis
    • DOI 10.1080/10286020600604260, PII 779554012
    • Li LH, Wu LJ, Tashiro SI, Onodera S, Uchiumi F, Ikejima T (2007) Activation of the SIRT1 pathway and modulation of the cell cycle were involved in silymarin's protection against UV-induced A375-S2 cell apoptosis. J Asian Nat Prod Res 9:245-252 (Pubitemid 46933325)
    • (2007) Journal of Asian Natural Products Research , vol.9 , Issue.3 , pp. 245-252
    • Li, L.-H.1    Wu, L.-J.2    Tashiro, S.-I.3    Onodera, S.4    Uchiumi, F.5    Ikejima, T.6
  • 92
    • 67449084948 scopus 로고    scopus 로고
    • Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
    • Li Y, Liu L, Andrews LG, Tollefsbol TO (2009a) Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer 125:286-296
    • (2009) Int J Cancer , vol.125 , pp. 286-296
    • Li, Y.1    Liu, L.2    Andrews, L.G.3    Tollefsbol, T.O.4
  • 93
    • 69249096109 scopus 로고    scopus 로고
    • Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
    • Li Y, VandenBoom Tn, Kong D, Wang Z, Ali S, Philip P, Sarkar F (2009b) Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res 69:6704-6712
    • (2009) Cancer Res , vol.69 , pp. 6704-6712
    • Li, Y.1    VandenBoom, Tn.2    Kong, D.3    Wang, Z.4    Ali, S.5    Philip, P.6    Sarkar, F.7
  • 94
    • 77952305618 scopus 로고    scopus 로고
    • Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression
    • Li Y, Liu L, Tollefsbol TO (2010) Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression. FASEB J 24:1442-1453
    • (2010) FASEB J , vol.24 , pp. 1442-1453
    • Li, Y.1    Liu, L.2    Tollefsbol, T.O.3
  • 95
    • 77953188130 scopus 로고    scopus 로고
    • Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer
    • Liang G, Tang A, Lin X, Li L, Zhang S, Huang Z, Tang H, Li QQ (2010) Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer. Int J Oncol 37:111-123
    • (2010) Int J Oncol , vol.37 , pp. 111-123
    • Liang, G.1    Tang, A.2    Lin, X.3    Li, L.4    Zhang, S.5    Huang, Z.6    Tang, H.7    Li, Q.Q.8
  • 97
    • 18744403080 scopus 로고    scopus 로고
    • Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation
    • DOI 10.1111/j.1745-7254.2005.00081.x
    • Liu H, Chen Y, Cui G, Zhou J (2005) Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating BNHL cell line Raji proliferation. Acta Pharmacol Sin 26:603-609 (Pubitemid 40676173)
    • (2005) Acta Pharmacologica Sinica , vol.26 , Issue.5 , pp. 603-609
    • Liu, H.-L.1    Chen, Y.2    Cui, G.-H.3    Zhou, J.-F.4
  • 98
    • 77957590701 scopus 로고    scopus 로고
    • Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factorkappaB pathway and subsequently downregulating expression of matrix metalloproteinases
    • Liu PL, Tsai JR, Charles AL, Hwang JJ, Chou SH, Ping YH, Lin FY, Chen YL, Hung CY, Chen WC, Chen YH, Chong IW (2010) Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factorkappaB pathway and subsequently downregulating expression of matrix metalloproteinases. Mol Nutr Food Res 54:S196-S204
    • (2010) Mol Nutr Food Res , vol.54
    • Liu, P.L.1    Tsai, J.R.2    Charles, A.L.3    Hwang, J.J.4    Chou, S.H.5    Ping, Y.H.6    Lin, F.Y.7    Chen, Y.L.8    Hung, C.Y.9    Chen, W.C.10    Chen, Y.H.11    Chong, I.W.12
  • 99
    • 42349103444 scopus 로고    scopus 로고
    • Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification
    • DOI 10.1158/0008-5472.CAN-07-2290
    • Majid S, Kikuno N, Nelles J, Noonan E, Tanaka Y, Kawamoto K, Hirata H, Li L, Zhao H, Okino S, Place R, Pookot D, Dahiya R (2008) Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification. Cancer Res 68:2736-2744 (Pubitemid 351556271)
    • (2008) Cancer Research , vol.68 , Issue.8 , pp. 2736-2744
    • Majid, S.1    Kikuno, N.2    Nelles, J.3    Noonan, E.4    Tanaka, Y.5    Kawamoto, K.6    Hirata, H.7    Li, L.C.8    Zhao, H.9    Okino, S.T.10    Place, R.F.11    Pookot, D.12    Dahiya, R.13
  • 101
    • 77954653079 scopus 로고    scopus 로고
    • Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines
    • (in press)
    • Mao QQ, Bai Y, Lin YW, Zheng XY, Qin J, Yang K, Xie LP (2010) Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines.Mol Nutr Food Res (in press)
    • (2010) Mol Nutr Food Res
    • Mao, Q.Q.1    Bai, Y.2    Lin, Y.W.3    Zheng, X.Y.4    Qin, J.5    Yang, K.6    Xie, L.P.7
  • 103
    • 49249116407 scopus 로고    scopus 로고
    • A work in progress: The clinical development of histone deacetylase inhibitors
    • Marsoni S, Damia G, Camboni G (2008) A work in progress: The clinical development of histone deacetylase inhibitors. Epigenetics 3:164-171
    • (2008) Epigenetics , vol.3 , pp. 164-171
    • Marsoni, S.1    Damia, G.2    Camboni, G.3
  • 104
    • 38449107684 scopus 로고    scopus 로고
    • Cell cycle control as a basis for cancer chemoprevention through dietary agents
    • DOI 10.2741/2834
    • Meeran S, Katiyar S (2008) Cell cycle control as a basis for cancer chemoprevention through dietary agents. Front Biosci 13:2191-2202 (Pubitemid 351589245)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.6 , pp. 2191-2202
    • Meeran, S.M.1    Katiyar, S.K.2
  • 105
    • 77955352742 scopus 로고    scopus 로고
    • Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
    • Meeran S, Patel S, Tollefsbol T (2010) Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS ONE 5:e11457
    • (2010) PLoS ONE , vol.5
    • Meeran, S.1    Patel, S.2    Tollefsbol, T.3
  • 107
    • 0345791481 scopus 로고    scopus 로고
    • Exceptionally High Protection of Photocarcinogenesis by Topical Application of (-)-Epigallocatechin-3-Gallate in Hydrophilic Cream in SKH-1 Hairless Mouse Model: Relationship to Inhibition of UVB-Induced Global DNA Hypomethylation
    • Mittal A, Piyathilake C, Hara Y, Katiyar S (2003) Exceptionally high protection of photocarcinogenesis by topical application of (-)- epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: Relationship to inhibition of UVB-induced global DNA hypomethylation. Neoplasia 5:555-565 (Pubitemid 38045092)
    • (2003) Neoplasia , vol.5 , Issue.6 , pp. 555-565
    • Mittal, A.1    Piyathilake, C.2    Hara, Y.3    Katiyar, S.K.4
  • 108
    • 36749087040 scopus 로고    scopus 로고
    • Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells
    • DOI 10.1158/1535-7163.MCT-07-0117
    • Moiseeva EP, Almeida GM, Jones GD, Manson MM (2007) Extended treatmentwith physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. Mol Cancer Ther 6:3071-3079 (Pubitemid 350206785)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.11 , pp. 3071-3079
    • Moiseeva, E.P.1    Almeida, G.M.2    Jones, G.D.D.3    Manson, M.M.4
  • 109
    • 41149141516 scopus 로고    scopus 로고
    • Histone deacetylases: Target enzymes for cancer therapy
    • Mottet D, Castronovo V (2008) Histone deacetylases: Target enzymes for cancer therapy. Clin Exp Metastasis 25:183-189
    • (2008) Clin Exp Metastasis , vol.25 , pp. 183-189
    • Mottet, D.1    Castronovo, V.2
  • 112
    • 0034080382 scopus 로고    scopus 로고
    • Tea polyphenols: Prevention of cancer and optimizing health
    • discussion 1703S-1694S
    • Mukhtar H, Ahmad N (2000) Tea polyphenols: Prevention of cancer and optimizing health. Am J Clin Nutr 71:1698S-1702S, discussion 1703S-1694S
    • (2000) Am J Clin Nutr , vol.71
    • Mukhtar, H.1    Ahmad, N.2
  • 113
    • 67650886038 scopus 로고    scopus 로고
    • Black tea polyphenols targetmatrixmetalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model
    • Murugan RS, Vinothini G, Hara Y, Nagini S (2009) Black tea polyphenols targetmatrixmetalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model. Anticancer Res 29:2301-2305
    • (2009) Anticancer Res , vol.29 , pp. 2301-2305
    • Murugan, R.S.1    Vinothini, G.2    Hara, Y.3    Nagini, S.4
  • 114
    • 4143130097 scopus 로고    scopus 로고
    • A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase
    • DOI 10.1158/0008-5472.CAN-04-1326
    • Myzak MC, Karplus PA, Chung FL, Dashwood RH (2004) A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase. Cancer Res 64:5767-5774 (Pubitemid 39095576)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5767-5774
    • Myzak, M.C.1    Karplus, P.A.2    Chung, F.-L.3    Dashwood, R.H.4
  • 115
    • 33645825587 scopus 로고    scopus 로고
    • min mice
    • DOI 10.1096/fj.05-4785fje
    • Myzak MC, Dashwood WM, Orner GA, Ho E, Dashwood RH (2006a) Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. FASEB J 20:506-508 (Pubitemid 46671231)
    • (2006) FASEB Journal , vol.20 , Issue.3 , pp. 506-508
    • Myzak, M.C.1    Dashwood, W.M.2    Orner, G.A.3    Ho, E.4    Dashwood, R.H.5
  • 116
    • 33645324413 scopus 로고    scopus 로고
    • Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
    • Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E (2006b) Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. Carcinogenesis 27:811-819
    • (2006) Carcinogenesis , vol.27 , pp. 811-819
    • Myzak, M.C.1    Hardin, K.2    Wang, R.3    Dashwood, R.H.4    Ho, E.5
  • 117
    • 33744990610 scopus 로고    scopus 로고
    • Dietary agents as histone deacetylase inhibitors
    • DOI 10.1002/mc.20224
    • Myzak M, Ho E, Dashwood R (2006c) Dietary agents as histone deacetylase inhibitors. Mol Carcinog 45:443-446 (Pubitemid 43865853)
    • (2006) Molecular Carcinogenesis , vol.45 , Issue.6 , pp. 443-446
    • Myzak, M.C.1    Ho, E.2    Dashwood, R.H.3
  • 118
    • 33846838750 scopus 로고    scopus 로고
    • Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
    • Myzak MC, Tong P, Dashwood WM, Dashwood RH, Ho E (2007) Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Exp Biol Med (Maywood) 232:227-234 (Pubitemid 46203291)
    • (2007) Experimental Biology and Medicine , vol.232 , Issue.2 , pp. 227-234
    • Myzak, M.C.1    Tong, P.2    Dashwood, W.-M.3    Dashwood, R.H.4    Ho, E.5
  • 119
    • 39149092699 scopus 로고    scopus 로고
    • Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells
    • DOI 10.1007/s11095-007-9364-7
    • Nair S, Hebbar V, Shen G, Gopalakrishnan A, Khor TO, Yu S, Xu C, Kong AN (2008) Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. Pharm Res 25:387-399 (Pubitemid 351257971)
    • (2008) Pharmaceutical Research , vol.25 , Issue.2 , pp. 387-399
    • Nair, S.1    Hebbar, V.2    Shen, G.3    Gopalakrishnan, A.4    Khor, T.O.5    Yu, S.6    Xu, C.7    Kong, A.-N.8
  • 120
    • 63049105405 scopus 로고    scopus 로고
    • Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds
    • Nian H, Delage B, Ho E, Dashwood R (2009) Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds. Environ Mol Mutagen 50:213-221
    • (2009) Environ Mol Mutagen , vol.50 , pp. 213-221
    • Nian, H.1    Delage, B.2    Ho, E.3    Dashwood, R.4
  • 121
    • 77953232497 scopus 로고    scopus 로고
    • Anti-melanoma effects of vorinostat in combination with polyphenolic antioxidant (-) - epigallocatechin-3-gallate (EGCG)
    • Nihal M, Roelke CT, Wood GS (2010) Anti-melanoma effects of vorinostat in combination with polyphenolic antioxidant (-)- epigallocatechin-3-gallate (EGCG). Pharm Res 27:1103-1114
    • (2010) Pharm Res , vol.27 , pp. 1103-1114
    • Nihal, M.1    Roelke, C.T.2    Wood, G.S.3
  • 122
    • 73749085369 scopus 로고    scopus 로고
    • The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells
    • Paluszczak J, Krajka-Kuzniak V, Baer-Dubowska W (2010) The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells. Toxicol Lett 192:119-125
    • (2010) Toxicol Lett , vol.192 , pp. 119-125
    • Paluszczak, J.1    Krajka-Kuzniak, V.2    Baer-Dubowska, W.3
  • 123
    • 77951225012 scopus 로고    scopus 로고
    • Promoter demethylation and chromatin remodeling by green tea polyphenols leads to reexpression of GSTP1 in human prostate cancer cells
    • Pandey M, Shukla S, Gupta S (2010) Promoter demethylation and chromatin remodeling by green tea polyphenols leads to reexpression of GSTP1 in human prostate cancer cells. Int J Cancer 126:2520-2533
    • (2010) Int J Cancer , vol.126 , pp. 2520-2533
    • Pandey, M.1    Shukla, S.2    Gupta, S.3
  • 124
    • 77956591357 scopus 로고    scopus 로고
    • Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells
    • Papoutsis AJ, Lamore SD, Wondrak GT, Selmin OI, Romagnolo DF (2010) Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells. J Nutr 140(9):1607-1614
    • (2010) J Nutr , vol.140 , Issue.9 , pp. 1607-1614
    • Papoutsis, A.J.1    Lamore, S.D.2    Wondrak, G.T.3    Selmin, O.I.4    Romagnolo, D.F.5
  • 126
    • 34147135143 scopus 로고    scopus 로고
    • Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines
    • DOI 10.1158/1535-7163.MCT-06-0494
    • Pledgie-Tracy A, Sobolewski MD, Davidson NE (2007) Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Mol Cancer Ther 6:1013-1021 (Pubitemid 46554571)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.3 , pp. 1013-1021
    • Pledgie-Tracy, A.1    Sobolewski, M.D.2    Davidson, N.E.3
  • 128
    • 65349090672 scopus 로고    scopus 로고
    • Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation
    • Pollack BP, Sapkota B, Boss JM (2009) Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. Photochem Photobiol 85:652-662
    • (2009) Photochem Photobiol , vol.85 , pp. 652-662
    • Pollack, B.P.1    Sapkota, B.2    Boss, J.M.3
  • 130
    • 27744529808 scopus 로고    scopus 로고
    • Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis
    • DOI 10.1093/carcin/bgi153
    • Quante M, Heeg S, von Werder A, Goessel G, Fulda C, Doebele M, Nakagawa H, Beijersbergen R, BlumH, Opitz O (2005) Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis. Carcinogenesis 26:1879-1889 (Pubitemid 41631260)
    • (2005) Carcinogenesis , vol.26 , Issue.11 , pp. 1879-1889
    • Quante, M.1    Heeg, S.2    Von Werder, A.3    Goessel, G.4    Fulda, C.5    Doebele, M.6    Nakagawa, H.7    Beijersbergen, R.8    Blum, H.E.9    Opitz, O.G.10
  • 131
    • 57749176653 scopus 로고    scopus 로고
    • Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia
    • Raynal NJ, Charbonneau M, Momparler LF, Momparler RL (2008) Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia. Oncol Res 17:223-230
    • (2008) Oncol Res , vol.17 , pp. 223-230
    • Raynal, N.J.1    Charbonneau, M.2    Momparler, L.F.3    Momparler, R.L.4
  • 132
    • 55949095821 scopus 로고    scopus 로고
    • Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
    • Reuter S, Eifes S, Dicato M, Aggarwal BB, Diederich M (2008) Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells. Biochem Pharmacol 76:1340-1351
    • (2008) Biochem Pharmacol , vol.76 , pp. 1340-1351
    • Reuter, S.1    Eifes, S.2    Dicato, M.3    Aggarwal, B.B.4    Diederich, M.5
  • 133
    • 77952180832 scopus 로고    scopus 로고
    • Green tea polyphenol suppresses tumor invasion and angiogenesis in Nbutyl-(- 4-hydroxybutyl) nitrosamine-induced bladder cancer
    • Sagara Y, Miyata Y, Nomata K, Hayashi T, Kanetake H (2010) Green tea polyphenol suppresses tumor invasion and angiogenesis in Nbutyl-(- 4-hydroxybutyl) nitrosamine-induced bladder cancer. Cancer Epidemiol 34:350-354
    • (2010) Cancer Epidemiol , vol.34 , pp. 350-354
    • Sagara, Y.1    Miyata, Y.2    Nomata, K.3    Hayashi, T.4    Kanetake, H.5
  • 134
    • 33749598345 scopus 로고    scopus 로고
    • Epigenetic activation of tumor suppressor microRNAs in human cancer cells
    • Saito Y, Jones P (2006) Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Cell Cycle 5:2220-2222 (Pubitemid 44546557)
    • (2006) Cell Cycle , vol.5 , Issue.19 , pp. 2220-2222
    • Saito, Y.1    Jones, P.A.2
  • 135
    • 4143059348 scopus 로고    scopus 로고
    • Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma
    • DOI 10.1016/j.urology.2004.03.045, PII S0090429504004170
    • Sasamura H, Takahashi A, Yuan J, Kitamura H, Masumori N, Miyao N, Itoh N, Tsukamoto T (2004) Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma. Urology 64:389-393 (Pubitemid 39092489)
    • (2004) Urology , vol.64 , Issue.2 , pp. 389-393
    • Sasamura, H.1    Takahashi, A.2    Yuan, J.3    Kitamura, H.4    Masumori, N.5    Miyao, N.6    Itoh, N.7    Tsukamoto, T.8
  • 136
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • DOI 10.1038/nature03672
    • Seligson D, Horvath S, Shi T, Yu H, Tze S, Grunstein M, Kurdistani S (2005) Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435:1262-1266 (Pubitemid 40943093)
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 139
    • 34447523548 scopus 로고    scopus 로고
    • Role of Curcumin in Cancer Therapy
    • DOI 10.1016/j.currproblcancer.2007.04.001, PII S0147027207000219, Role of Curcumin in Cancer Therapy
    • Shishodia S, Chaturvedi M, Aggarwal B (2007) Role of curcumin in cancer therapy. Curr Probl Cancer 31:243-305 (Pubitemid 47077491)
    • (2007) Current Problems in Cancer , vol.31 , Issue.4 , pp. 243-305
    • Shishodia, S.1    Chaturvedi, M.M.2    Aggarwal, B.B.3
  • 140
    • 32944478433 scopus 로고    scopus 로고
    • Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis
    • DOI 10.1158/0008-5472.CAN-05-1332
    • Singh AV, Franke AA, Blackburn GL, Zhou JR (2006) Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis. Cancer Res 66:1851-1858 (Pubitemid 43259972)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1851-1858
    • Singh, A.V.1    Franke, A.A.2    Blackburn, G.L.3    Zhou, J.-R.4
  • 141
    • 77953539793 scopus 로고    scopus 로고
    • Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells
    • Stefanska B, Rudnicka K, Bednarek A, Fabianowska-Majewska K (2010) Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells. Eur J Pharmacol 638:47-53
    • (2010) Eur J Pharmacol , vol.638 , pp. 47-53
    • Stefanska, B.1    Rudnicka, K.2    Bednarek, A.3    Fabianowska-Majewska, K.4
  • 143
    • 70349316774 scopus 로고    scopus 로고
    • Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression
    • Sun Q, Cong R, Yan H, Gu H, Zeng Y, Liu N, Chen J, Wang B (2009) Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression. Oncol Rep 22:563-567
    • (2009) Oncol Rep , vol.22 , pp. 563-567
    • Sun, Q.1    Cong, R.2    Yan, H.3    Gu, H.4    Zeng, Y.5    Liu, N.6    Chen, J.7    Wang, B.8
  • 144
    • 69349093211 scopus 로고    scopus 로고
    • Environmental influences on epigenetic profiles
    • Suter M, Aagaard-Tillery K (2009) Environmental influences on epigenetic profiles. Semin Reprod Med 27:380-390
    • (2009) Semin Reprod Med , vol.27 , pp. 380-390
    • Suter, M.1    Aagaard-Tillery, K.2
  • 145
    • 57349126317 scopus 로고    scopus 로고
    • Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein
    • Tang W, Newbold R, Mardilovich K, Jefferson W, Cheng R, Medvedovic M, Ho S (2008) Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein. Endocrinology 149:5922-5931
    • (2008) Endocrinology , vol.149 , pp. 5922-5931
    • Tang, W.1    Newbold, R.2    Mardilovich, K.3    Jefferson, W.4    Cheng, R.5    Medvedovic, M.6    Ho, S.7
  • 146
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • DOI 10.1016/0959-437X(93)90027-M
    • Tate P, Bird A (1993) Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev 3:226-231 (Pubitemid 23108662)
    • (1993) Current Opinion in Genetics and Development , vol.3 , Issue.2 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 147
    • 63349102182 scopus 로고    scopus 로고
    • Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells
    • Telang U, Brazeau D, Morris M (2009) Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells. Exp Biol Med (Maywood) 234:287-295
    • (2009) Exp Biol Med (Maywood) , vol.234 , pp. 287-295
    • Telang, U.1    Brazeau, D.2    Morris, M.3
  • 148
    • 40949119020 scopus 로고    scopus 로고
    • Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy
    • DOI 10.1038/sj.bjp.0707666, PII 0707666
    • Tikoo K, Meena R, Kabra D, Gaikwad A (2008) Change in posttranslational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocininduced type I diabetic nephropathy. Br J Pharmacol 153:1225-1231 (Pubitemid 351415498)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.6 , pp. 1225-1231
    • Tikoo, K.1    Meena, R.L.2    Kabra, D.G.3    Gaikwad, A.B.4
  • 150
    • 77954887577 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo
    • Tran PL, Kim SA, Choi HS, Yoon JH, Ahn SG (2010) Epigallocatechin-3- gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo. BMC Cancer 10:276
    • (2010) BMC Cancer , vol.10 , pp. 276
    • Tran, P.L.1    Kim, S.A.2    Choi, H.S.3    Yoon, J.H.4    Ahn, S.G.5
  • 152
    • 77952611330 scopus 로고    scopus 로고
    • Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/ Wnt and activation of p53 signaling pathways
    • Vanamala J, Reddivari L, Radhakrishnan S, Tarver C (2010) Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/ Wnt and activation of p53 signaling pathways. BMC Cancer 10:238
    • (2010) BMC Cancer , vol.10 , pp. 238
    • Vanamala, J.1    Reddivari, L.2    Radhakrishnan, S.3    Tarver, C.4
  • 153
    • 70349975929 scopus 로고    scopus 로고
    • Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer
    • Volate SR, Muga SJ, Issa AY, Nitcheva D, Smith T, Wargovich MJ (2009) Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. Mol Carcinog 48:920-933
    • (2009) Mol Carcinog , vol.48 , pp. 920-933
    • Volate, S.R.1    Muga, S.J.2    Issa, A.Y.3    Nitcheva, D.4    Smith, T.5    Wargovich, M.J.6
  • 154
    • 0035542974 scopus 로고    scopus 로고
    • Methyl CpG-binding proteins and transcriptional repression
    • Wade P (2001) Methyl CpG-binding proteins and transcriptional repression. Bioessays 23:1131-1137
    • (2001) Bioessays , vol.23 , pp. 1131-1137
    • Wade, P.1
  • 156
    • 0034928799 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by dietary polyphenolic compounds
    • DOI 10.1146/annurev.nutr.21.1.381
    • Yang C, Landau J, Huang M, Newmark H (2001) Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu Rev Nutr 21:381-406 (Pubitemid 32695277)
    • (2001) Annual Review of Nutrition , vol.21 , pp. 381-406
    • Yang, C.S.1    Landau, J.M.2    Huang, M.-T.3    Newmark, H.L.4
  • 159
    • 77954595294 scopus 로고    scopus 로고
    • Effects of epigallocatechin gallate on regulatory T cell number and function in obese v. lean volunteers
    • Yun JM, Jialal I, Devaraj S (2010a) Effects of epigallocatechin gallate on regulatory T cell number and function in obese v. lean volunteers. Br J Nutr 103:1771-1777
    • (2010) Br J Nutr , vol.103 , pp. 1771-1777
    • Yun, J.M.1    Jialal, I.2    Devaraj, S.3
  • 160
    • 79952363576 scopus 로고    scopus 로고
    • Epigenetic regulation of high glucose-induced proinflammatory cytokine production inmonocytes by curcumin
    • (in press)
    • Yun JM, Jialal I, Devaraj S (2010b) Epigenetic regulation of high glucose-induced proinflammatory cytokine production inmonocytes by curcumin. J Nutr Biochem (in press)
    • (2010) J Nutr Biochem
    • Yun, J.M.1    Jialal, I.2    Devaraj, S.3


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