-
1
-
-
25144440127
-
Rational development of histone deacetylase inhibitors as anticancer agents: A review
-
DOI 10.1124/mol.105.014167
-
Acharya M, Sparreboom A, Venitz J, Figg W (2005) Rational development of histone deacetylase inhibitors as anticancer agents: A review. Mol Pharmacol 68:917-932 (Pubitemid 41345783)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.4
, pp. 917-932
-
-
Acharya, M.R.1
Sparreboom, A.2
Venitz, J.3
Figg, W.D.4
-
2
-
-
33646028804
-
Molecular targets of dietary agents for prevention and therapy of cancer
-
Aggarwal B, Shishodia S (2006) Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 71:1397-1421
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1397-1421
-
-
Aggarwal, B.1
Shishodia, S.2
-
3
-
-
0037236792
-
Anticancer potential of curcumin: Preclinical and clinical studies
-
Aggarwal B, Kumar A, Bharti A (2003) Anticancer potential of curcumin: Preclinical and clinical studies. Anticancer Res 23:363-398 (Pubitemid 36361976)
-
(2003)
Anticancer Research
, vol.23
, Issue.1
, pp. 363-398
-
-
Aggarwal, B.B.1
Kumar, A.2
Bharti, A.C.3
-
4
-
-
0031444312
-
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
-
Ahmad N, Feyes D, Nieminen A, Agarwal R, Mukhtar H (1997) Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst 89:1881-1886 (Pubitemid 28009824)
-
(1997)
Journal of the National Cancer Institute
, vol.89
, Issue.24
, pp. 1881-1886
-
-
Ahmad, N.1
Feyes, D.K.2
Nieminen, A.-L.3
Agarwal, R.4
Mukhtar, H.5
-
5
-
-
67349128956
-
Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms
-
Athar M, Back J, Kopelovich L, Bickers D, Kim A (2009) Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms. Arch Biochem Biophys 486:95-102
-
(2009)
Arch Biochem Biophys
, vol.486
, pp. 95-102
-
-
Athar, M.1
Back, J.2
Kopelovich, L.3
Bickers, D.4
Kim, A.5
-
6
-
-
0346888660
-
Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes
-
DOI 10.1093/carcin/bgg157
-
Bacon JR, Williamson G, Garner RC, Lappin G, Langouet S, Bao Y (2003) Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes. Carcinogenesis 24:1903-1911 (Pubitemid 38008530)
-
(2003)
Carcinogenesis
, vol.24
, Issue.12
, pp. 1903-1911
-
-
Bacon, J.R.1
Williamson, G.2
Garner, R.C.3
Lappin, G.4
Langouet, S.5
Bao, Y.6
-
7
-
-
77950907191
-
The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3- gallatedependent suppression of skin cancer cell survival
-
Balasubramanian S, Adhikary G, Eckert RL (2010) The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallatedependent suppression of skin cancer cell survival. Carcinogenesis 31:496-503
-
(2010)
Carcinogenesis
, vol.31
, pp. 496-503
-
-
Balasubramanian, S.1
Adhikary, G.2
Eckert, R.L.3
-
8
-
-
10944243759
-
Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
-
DOI 10.1074/jbc.M409024200
-
Balasubramanyam K, Varier R, Altaf M, Swaminathan V, Siddappa N, Ranga U, Kundu T (2004) Curcumin, a novel p300/CREBbinding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem 279:51163-51171 (Pubitemid 40017859)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.49
, pp. 51163-51171
-
-
Balasubramanyam, K.1
Varier, R.A.2
Altaf, M.3
Swaminathan, V.4
Siddappa, N.B.5
Ranga, U.6
Kundu, T.K.7
-
9
-
-
0035169663
-
Methyl-CpG-binding proteins: Targeting specific gene repression
-
DOI 10.1046/j.1432-1327.2001.01869.x
-
Ballestar E, Wolffe A (2001) Methyl-CpG-binding proteins. Targeting specific gene repression. Eur J Biochem 268:1-6 (Pubitemid 32052241)
-
(2001)
European Journal of Biochemistry
, vol.268
, Issue.1
, pp. 1-6
-
-
Ballestar, E.1
Wolffe, A.P.2
-
10
-
-
0028815434
-
Effect of genistein on in vitro and in vivo models of cancer
-
Barnes S (1995) Effect of genistein on in vitro and in vivo models of cancer. J Nutr 125:777S-783S
-
(1995)
J Nutr
, vol.125
-
-
Barnes, S.1
-
11
-
-
38649100332
-
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG
-
DOI 10.1002/jcb.21417
-
Berletch JB, Liu C, Love WK, Andrews LG, Katiyar SK, Tollefsbol TO (2008) Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG. J Cell Biochem 103:509-519 (Pubitemid 351171921)
-
(2008)
Journal of Cellular Biochemistry
, vol.103
, Issue.2
, pp. 509-519
-
-
Berletch, J.B.1
Liu, C.2
Love, W.K.3
Andrews, L.G.4
Katiyar, S.K.5
Tollefsbol, T.O.6
-
12
-
-
0033753779
-
The DNA methyltransferases of mammals
-
Bestor T (2000) The DNA methyltransferases of mammals. Hum Mol Genet 9:2395-2402
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2395-2402
-
-
Bestor, T.1
-
13
-
-
58849084204
-
Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells
-
Bhamre S, Sahoo D, Tibshirani R, Dill D, Brooks J (2009) Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells. Prostate 69:181-190
-
(2009)
Prostate
, vol.69
, pp. 181-190
-
-
Bhamre, S.1
Sahoo, D.2
Tibshirani, R.3
Dill, D.4
Brooks, J.5
-
14
-
-
34249337761
-
Perceptions of epigenetics
-
DOI 10.1038/nature05913, PII NATURE05913
-
Bird A (2007) Perceptions of epigenetics. Nature 447:396-398 (Pubitemid 46816744)
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 396-398
-
-
Bird, A.1
-
15
-
-
67650297506
-
Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials
-
Bishayee A (2009) Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials. Cancer Prev Res (Phila Pa) 2:409-418
-
(2009)
Cancer Prev Res (Phila Pa)
, vol.2
, pp. 409-418
-
-
Bishayee, A.1
-
16
-
-
45549098657
-
SirT1 regulates energy metabolism and response to caloric restriction in mice
-
Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, Moffat C, Crawford S, Saliba S, Jardine K, Xuan J, Evans M, Harper ME, McBurney MW (2008) SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS ONE 3:e1759
-
(2008)
PLoS ONE
, vol.3
-
-
Boily, G.1
Seifert, E.L.2
Bevilacqua, L.3
He, X.H.4
Sabourin, G.5
Estey, C.6
Moffat, C.7
Crawford, S.8
Saliba, S.9
Jardine, K.10
Xuan, J.11
Evans, M.12
Harper, M.E.13
McBurney, M.W.14
-
17
-
-
68949113934
-
SirT1- null mice develop tumors at normal rates but are poorly protected by resveratrol
-
Boily G, He XH, Pearce B, Jardine K, McBurney MW (2009) SirT1- null mice develop tumors at normal rates but are poorly protected by resveratrol. Oncogene 28:2882-2893
-
(2009)
Oncogene
, vol.28
, pp. 2882-2893
-
-
Boily, G.1
He, X.H.2
Pearce, B.3
Jardine, K.4
McBurney, M.W.5
-
18
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
DOI 10.1038/nrd2133, PII NRD2133
-
Bolden J, Peart M, Johnstone R (2006) Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov 5:769-784 (Pubitemid 44348499)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.9
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
19
-
-
77950552489
-
Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells
-
Bryant CS, Kumar S, Chamala S, Shah J, Pal J, Haider M, Seward S, Qazi AM, Morris R, Semaan A, Shammas MA, Steffes C, Potti RB, Prasad M, Weaver DW, Batchu RB (2010) Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Mol Cancer 9:47
-
(2010)
Mol Cancer
, vol.9
, pp. 47
-
-
Bryant, C.S.1
Kumar, S.2
Chamala, S.3
Shah, J.4
Pal, J.5
Haider, M.6
Seward, S.7
Qazi, A.M.8
Morris, R.9
Semaan, A.10
Shammas, M.A.11
Steffes, C.12
Potti, R.B.13
Prasad, M.14
Weaver, D.W.15
Batchu, R.B.16
-
20
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
DOI 10.1073/pnas.0307323101
-
Calin G, Sevignani C, Dumitru C, Hyslop T, Noch E, Yendamuri S, Shimizu M, Rattan S, Bullrich F, Negrini M, Croce C (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101:2999-3004 (Pubitemid 38327724)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.9
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
Shimizu, M.7
Rattan, S.8
Bullrich, F.9
Negrini, M.10
Croce, C.M.11
-
21
-
-
36248957463
-
Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells
-
DOI 10.1111/j.1742-7843.2007.00142.x
-
Chen Y, Shu W, Chen W, Wu Q, Liu H, Cui G (2007) Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells. Basic Clin Pharmacol Toxicol 101:427-433 (Pubitemid 350135350)
-
(2007)
Basic and Clinical Pharmacology and Toxicology
, vol.101
, Issue.6
, pp. 427-433
-
-
Chen, Y.1
Shu, W.2
Chen, W.3
Wu, Q.4
Liu, H.5
Cui, G.6
-
22
-
-
77449106593
-
Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention
-
Cheung KL, Kong AN (2010) Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention. AAPS J 12:87-97
-
(2010)
AAPS J
, vol.12
, pp. 87-97
-
-
Cheung, K.L.1
Kong, A.N.2
-
23
-
-
67651182607
-
Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB
-
Chiu J, Khan Z, Farhangkhoee H, Chakrabarti S (2009) Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB. Nutrition 25:964-972
-
(2009)
Nutrition
, vol.25
, pp. 964-972
-
-
Chiu, J.1
Khan, Z.2
Farhangkhoee, H.3
Chakrabarti, S.4
-
24
-
-
58349094740
-
Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation
-
Choi KC, Jung MG, Lee YH, Yoon JC, Kwon SH, Kang HB, Kim MJ, Cha JH, Kim YJ, Jun WJ, Lee JM, Yoon HG (2009) Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res 69:583-592
-
(2009)
Cancer Res
, vol.69
, pp. 583-592
-
-
Choi, K.C.1
Jung, M.G.2
Lee, Y.H.3
Yoon, J.C.4
Kwon, S.H.5
Kang, H.B.6
Kim, M.J.7
Cha, J.H.8
Kim, Y.J.9
Jun, W.J.10
Lee, J.M.11
Yoon, H.G.12
-
25
-
-
77953126448
-
Molecular targets of epigenetic regulation and effectors of environmental influences
-
Choudhuri S, Cui Y, Klaassen C (2010) Molecular targets of epigenetic regulation and effectors of environmental influences. Toxicol Appl Pharmacol 245:378-393
-
(2010)
Toxicol Appl Pharmacol
, vol.245
, pp. 378-393
-
-
Choudhuri, S.1
Cui, Y.2
Klaassen, C.3
-
26
-
-
70349929035
-
Sulforaphane induces G2-M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma
-
Chu WF, Wu DM, Liu W, Wu LJ, Li DZ, Xu DY, Wang XF (2009) Sulforaphane induces G2-M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma. Oral Oncol 45:998-1004
-
(2009)
Oral Oncol
, vol.45
, pp. 998-1004
-
-
Chu, W.F.1
Wu, D.M.2
Liu, W.3
Wu, L.J.4
Li, D.Z.5
Xu, D.Y.6
Wang, X.F.7
-
27
-
-
34547795788
-
Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast
-
DOI 10.1093/carcin/bgm049
-
Cornblatt BS, Ye L, Dinkova-Kostova AT, Erb M, Fahey JW, Singh NK, Chen MS, Stierer T, Garrett-Mayer E, Argani P, Davidson NE, Talalay P, Kensler TW, Visvanathan K (2007) Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast. Carcinogenesis 28:1485-1490 (Pubitemid 47241798)
-
(2007)
Carcinogenesis
, vol.28
, Issue.7
, pp. 1485-1490
-
-
Cornblatt, B.S.1
Ye, L.2
Dinkova-Kostova, A.T.3
Erb, M.4
Fahey, J.W.5
Singh, N.K.6
Chen, M.-S.A.7
Stierer, T.8
Garrett-Mayer, E.9
Argani, P.10
Davidson, N.E.11
Talalay, P.12
Kensler, T.W.13
Visvanathan, K.14
-
28
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
Croce C (2009) Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 10:704-714
-
(2009)
Nat Rev Genet
, vol.10
, pp. 704-714
-
-
Croce, C.1
-
29
-
-
34447546839
-
PfGCN5-mediated histone H3 acetylation plays a key role in gene expression in Plasmodium falciparum
-
DOI 10.1128/EC.00062-07
-
Cui L, Miao J, Furuya T, Li X, Su XZ (2007) PfGCN5-mediated histone H3 acetylation plays a key role in gene expression in Plasmodium falciparum. Eukaryot Cell 6:1219-1227 (Pubitemid 47077173)
-
(2007)
Eukaryotic Cell
, vol.6
, Issue.7
, pp. 1219-1227
-
-
Cui, L.1
Miao, J.2
Furuya, T.3
Li, X.4
Su, X.-Z.5
Cui, L.6
-
30
-
-
77149156308
-
The role of histone modifications and variants in regulating gene expression in breast cancer
-
Dalvai M, Bystricky K (2010) The role of histone modifications and variants in regulating gene expression in breast cancer. J Mammary Gland Biol Neoplasia 15:19-33
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 19-33
-
-
Dalvai, M.1
Bystricky, K.2
-
31
-
-
34548456881
-
Dietary histone deacetylase inhibitors: From cells to mice to man
-
DOI 10.1016/j.semcancer.2007.04.001, PII S1044579X07000247
-
Dashwood RH, Ho E (2007) Dietary histone deacetylase inhibitors: From cells to mice to man. Semin Cancer Biol 17:363-369 (Pubitemid 47369168)
-
(2007)
Seminars in Cancer Biology
, vol.17
, Issue.5
, pp. 363-369
-
-
Dashwood, R.H.1
Ho, E.2
-
32
-
-
48349084189
-
Dietary agents as histone deacetylase inhibitors: Sulforaphane and structurally related isothiocyanates
-
Dashwood R, Ho E (2008) Dietary agents as histone deacetylase inhibitors: Sulforaphane and structurally related isothiocyanates. Nutr Rev 66(Suppl 1):S36-S38
-
(2008)
Nutr Rev
, vol.66
, Issue.SUPPL. 1
-
-
Dashwood, R.1
Ho, E.2
-
33
-
-
33947515716
-
Dietary components impact histone modifications and cancer risk
-
DOI 10.1111/j.1753-4887.2007.tb00285.x
-
Davis CD, Ross SA (2007) Dietary components impact histone modifications and cancer risk. Nutr Rev 65:88-94 (Pubitemid 351804383)
-
(2007)
Nutrition Reviews
, vol.65
, Issue.2
, pp. 88-94
-
-
Davis, C.D.1
Ross, S.A.2
-
34
-
-
3242721652
-
Genistein alters methylation patterns in mice
-
Day J, Bauer A, DesBordes C, Zhuang Y, Kim B, Newton L, Nehra V, Forsee K, MacDonald R, Besch-Williford C, Huang T, Lubahn D (2002) Genistein alters methylation patterns in mice. J Nutr 132:2419S-2423S (Pubitemid 34848119)
-
(2002)
Journal of Nutrition
, vol.132
, Issue.8 SUPPL.
-
-
Kevin Day, J.1
Bauer, A.M.2
Desbordes, C.3
Zhuang, Y.4
Kim, B.-E.5
Newton, L.G.6
Nehra, V.7
Forsee, K.M.8
MacDonald, R.S.9
Besch-Williford, C.10
Huang, T.H.-M.11
Lubahn, D.B.12
-
35
-
-
34247473917
-
Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts
-
DOI 10.1158/1055-9965.EPI-06-0934
-
Dinkova-Kostova AT, Fahey JW, Wade KL, Jenkins SN, Shapiro TA, Fuchs EJ, Kerns ML, Talalay P (2007) Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiol Biomark Prev 16:847-851 (Pubitemid 46650594)
-
(2007)
Cancer Epidemiology Biomarkers and Prevention
, vol.16
, Issue.4
, pp. 847-851
-
-
Dinkova-Kostova, A.T.1
Fahey, J.W.2
Wade, K.L.3
Jenkins, S.N.4
Shapiro, T.A.5
Fuchs, E.J.6
Kerns, M.L.7
Talalay, P.8
-
36
-
-
3242755145
-
waf1/cip1 expression in human colon tumor cell lines
-
DOI 10.1093/carcin/bgh123
-
Druesne N, Pagniez A, Mayeur C, Thomas M, Cherbuy C, Duée P, Martel P, Chaumontet C (2004) Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines. Carcinogenesis 25:1227-1236 (Pubitemid 38968051)
-
(2004)
Carcinogenesis
, vol.25
, Issue.7
, pp. 1227-1236
-
-
Druesne, N.1
Pagniez, A.2
Mayeur, C.3
Thomas, M.4
Cherbuy, C.5
Duee, P.-H.6
Martel, P.7
Chaumontet, C.8
-
37
-
-
33845211776
-
Epigenetic aberrations and cancer
-
Ducasse M, Brown M (2006) Epigenetic aberrations and cancer. Mol Cancer 5:60
-
(2006)
Mol Cancer
, vol.5
, pp. 60
-
-
Ducasse, M.1
Brown, M.2
-
38
-
-
0032508952
-
Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey
-
Eisenberg D, Davis R, Ettner S, Appel S, Wilkey S, Van Rompay M, Kessler R (1998) Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey. JAMA 280:1569-1575 (Pubitemid 28520643)
-
(1998)
Journal of the American Medical Association
, vol.280
, Issue.18
, pp. 1569-1575
-
-
Eisenberg, D.M.1
Davis, R.B.2
Ettner, S.L.3
Appel, S.4
Wilkey, S.5
Van Rompay, M.6
Kessler, R.C.7
-
39
-
-
67649305191
-
Epigenetics in cancer: Targeting chromatin modifications
-
Ellis L, Atadja P, Johnstone R (2009) Epigenetics in cancer: Targeting chromatin modifications. Mol Cancer Ther 8:1409-1420
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1409-1420
-
-
Ellis, L.1
Atadja, P.2
Johnstone, R.3
-
40
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
DOI 10.1038/nrg2005, PII NRG2005
-
Esteller M (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8:286-298 (Pubitemid 46439286)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.4
, pp. 286-298
-
-
Esteller, M.1
-
41
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M (2008) Epigenetics in cancer. N Engl J Med 358:1148-1159
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
42
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
DOI 10.1073/pnas.0707628104
-
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, Liu S, Alder H, Costinean S, Fernandez-Cymering C, Volinia S, Guler G, Morrison C, Chan K, Marcucci G, Calin G, Huebner K, Croce C (2007) MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA 104:15805-15810 (Pubitemid 350035380)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.40
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
Liu, S.7
Alder, H.8
Costinean, S.9
Fernandez-Cymering, C.10
Volinia, S.11
Guler, G.12
Morrison, C.D.13
Chan, K.K.14
Marcucci, G.15
Calin, G.A.16
Huebner, K.17
Croce, C.M.18
-
43
-
-
0345275879
-
Tea Polyphenol (-)-Epigallocatechin-3-Gallate Inhibits DNA Methyltransferase and Reactivates Methylation-Silenced Genes in Cancer Cell Lines
-
Fang M, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W, Yang C (2003) Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 63:7563-7570 (Pubitemid 37466673)
-
(2003)
Cancer Research
, vol.63
, Issue.22
, pp. 7563-7570
-
-
Fang, M.Z.1
Wang, Y.2
Ai, N.3
Hou, Z.4
Sun, Y.5
Lu, H.6
Welsh, W.7
Yang, C.S.8
-
44
-
-
26444451123
-
INK4a, RARβ, and MGMT genes by genistein and other isoflavones from soy
-
DOI 10.1158/1078-0432.CCR-05-0406
-
Fang M, Chen D, Sun Y, Jin Z, Christman J, Yang C (2005) Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 11:7033-7041 (Pubitemid 41428763)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.19
, pp. 7033-7041
-
-
Fang, M.Z.1
Chen, D.2
Sun, Y.3
Jin, Z.4
Christman, J.K.5
Yang, C.S.6
-
45
-
-
33845969839
-
Dietary polyphenols may affect DNA methylation
-
Fang M, Chen D, Yang C (2007) Dietary polyphenols may affect DNA methylation. J Nutr 137:223S-228S (Pubitemid 46052885)
-
(2007)
Journal of Nutrition
, vol.137
, Issue.1
-
-
Fang, M.1
Chen, D.2
Yang, C.S.3
-
46
-
-
3242664189
-
Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate
-
DOI 10.1158/1078-0432.CCR-03-0672
-
Fassina G, Venè R, Morini M, Minghelli S, Benelli R, Noonan D, Albini A (2004) Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate. Clin Cancer Res 10:4865-4873 (Pubitemid 38955541)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.14
, pp. 4865-4873
-
-
Fassina, G.1
Vene, R.2
Morini, M.3
Minghelli, S.4
Benelli, R.5
Noonan, D.M.6
Albini, A.7
-
47
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga M, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer N, Pérez-Rosado A, Calvo E, Lopez J, Cano A, Calasanz M, Colomer D, Piris M, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M (2005) Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37:391-400
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.1
Ballestar, E.2
Villar-Garea, A.3
Boix-Chornet, M.4
Espada, J.5
Schotta, G.6
Bonaldi, T.7
Haydon, C.8
Ropero, S.9
Petrie, K.10
Iyer, N.11
Pérez-Rosado, A.12
Calvo, E.13
Lopez, J.14
Cano, A.15
Calasanz, M.16
Colomer, D.17
Piris, M.18
Ahn, N.19
Imhof, A.20
Caldas, C.21
Jenuwein, T.22
Esteller, M.23
more..
-
48
-
-
78349269863
-
Development of curcumin as an epigenetic agent
-
(in press)
-
Fu S, Kurzrock R (2010) Development of curcumin as an epigenetic agent. Cancer (in press)
-
(2010)
Cancer
-
-
Fu, S.1
Kurzrock, R.2
-
49
-
-
74849127193
-
Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery
-
Ganesan A, Nolan L, Crabb SJ, Packham G (2009) Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery. Curr Cancer Drug Targets 9:963-981
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 963-981
-
-
Ganesan, A.1
Nolan, L.2
Crabb, S.J.3
Packham, G.4
-
50
-
-
67650892068
-
Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells
-
Gao Z, Xu Z, Hung MS, Lin YC, Wang T, Gong M, Zhi X, Jablon DM, You L (2009) Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells. Anticancer Res 29:2025-2030
-
(2009)
Anticancer Res
, vol.29
, pp. 2025-2030
-
-
Gao, Z.1
Xu, Z.2
Hung, M.S.3
Lin, Y.C.4
Wang, T.5
Gong, M.6
Zhi, X.7
Jablon, D.M.8
You, L.9
-
51
-
-
30544442161
-
Histone acetylation increases chromatin accessibility
-
DOI 10.1242/jcs.02689
-
Görisch S, Wachsmuth M, Tòth K, Lichter P, Rippe K (2005) Histone acetylation increases chromatin accessibility. J Cell Sci 118:5825-5834 (Pubitemid 43079275)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.24
, pp. 5825-5834
-
-
Gorisch, S.M.1
Wachsmuth, M.2
Toth, K.F.3
Lichter, P.4
Rippe, K.5
-
52
-
-
0026771060
-
Green tea composition, consumption, and polyphenol chemistry
-
Graham H (1992) Green tea composition, consumption, and polyphenol chemistry. Prev Med 21:334-350
-
(1992)
Prev Med
, vol.21
, pp. 334-350
-
-
Graham, H.1
-
53
-
-
36549056015
-
Epigenetic changes in cancer
-
DOI 10.1111/j.1600-0463.2007.apm-636.xml.x
-
Grønbaek K, Hother C, Jones P (2007) Epigenetic changes in cancer. APMIS 115:1039-1059 (Pubitemid 350179474)
-
(2007)
APMIS
, vol.115
, Issue.10
, pp. 1039-1059
-
-
Gronbaek, K.1
Hother, C.2
Jones, P.A.3
-
54
-
-
31344441221
-
Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis
-
Gu Y, Zhu CF, Iwamoto H, Chen JS (2005) Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis. World J Gastroenterol 11:6512-6517 (Pubitemid 43136890)
-
(2005)
World Journal of Gastroenterology
, vol.11
, Issue.41
, pp. 6512-6517
-
-
Gu, Y.1
Zhu, C.-F.2
Iwamoto, H.3
Chen, J.-S.4
-
55
-
-
64849110824
-
EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression
-
Gu B, Ding Q, Xia G, Fang Z (2009) EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression. Oncol Rep 21:635-640
-
(2009)
Oncol Rep
, vol.21
, pp. 635-640
-
-
Gu, B.1
Ding, Q.2
Xia, G.3
Fang, Z.4
-
56
-
-
52949108784
-
Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
-
Guerrero-Bosagna C, Sabat P, Valdovinos F, Valladares L, Clark S (2008) Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC Physiol 8:17
-
(2008)
BMC Physiol
, vol.8
, pp. 17
-
-
Guerrero-Bosagna, C.1
Sabat, P.2
Valdovinos, F.3
Valladares, L.4
Clark, S.5
-
57
-
-
55949134303
-
DNA methylomes, histone codes and miRNAs: Tying it all together
-
Guil S, Esteller M (2009) DNA methylomes, histone codes and miRNAs: Tying it all together. Int J Biochem Cell Biol 41:87-95
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 87-95
-
-
Guil, S.1
Esteller, M.2
-
58
-
-
8444247426
-
Unusual distribution of DNA methylation within the hTERT CpG island in tissues and cell lines
-
DOI 10.1016/j.bbrc.2004.10.137, PII S0006291X04024829
-
Guilleret I, Benhattar J (2004) Unusual distribution of DNA methylation within the hTERT CpG island in tissues and cell lines. Biochem Biophys Res Commun 325:1037-1043 (Pubitemid 39487975)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.325
, Issue.3
, pp. 1037-1043
-
-
Guilleret, I.1
Benhattar, J.2
-
59
-
-
0024003456
-
A direct link between core histone acetylation and transcriptionally active chromatin
-
Hebbes T, Thorne A, Crane-Robinson C (1988) A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J 7:1395-1402
-
(1988)
EMBO J
, vol.7
, pp. 1395-1402
-
-
Hebbes, T.1
Thorne, A.2
Crane-Robinson, C.3
-
61
-
-
33847613305
-
Epigenetics and cancer: Towards an evaluation of the impact of environmental and dietary factors
-
DOI 10.1093/mutage/gel068
-
Herceg Z (2007) Epigenetics and cancer: Towards an evaluation of the impact of environmental and dietary factors.Mutagenesis 22:91-103 (Pubitemid 46364521)
-
(2007)
Mutagenesis
, vol.22
, Issue.2
, pp. 91-103
-
-
Herceg, Z.1
-
62
-
-
34250757157
-
Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line
-
DOI 10.1158/1535-7163.MCT-06-0807
-
Herman-Antosiewicz A, Xiao H, Lew KL, Singh SV (2007) Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line. Mol Cancer Ther 6:1673-1681 (Pubitemid 46954034)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.5
, pp. 1673-1681
-
-
Herman-Antosiewicz, A.1
Xiao, H.2
Lew, K.L.3
Singh, S.V.4
-
63
-
-
34047136753
-
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
-
DOI 10.1016/j.phrs.2007.01.009, PII S1043661807000321, Nutritional Pharmacology
-
Higdon JV, Delage B, Williams DE, Dashwood RH (2007) Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis. Pharmacol Res 55:224-236 (Pubitemid 46518152)
-
(2007)
Pharmacological Research
, vol.55
, Issue.3
, pp. 224-236
-
-
Higdon, J.V.1
Delage, B.2
Williams, D.E.3
Dashwood, R.H.4
-
64
-
-
72249122960
-
Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention
-
Ho E, Clarke JD, Dashwood RH (2009) Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr 139:2393-2396
-
(2009)
J Nutr
, vol.139
, pp. 2393-2396
-
-
Ho, E.1
Clarke, J.D.2
Dashwood, R.H.3
-
65
-
-
0025116236
-
Mechanisms for the control of gene activity during development
-
Holliday R (1990) Mechanisms for the control of gene activity during development. Biol Rev Camb Philos Soc 65:431-471
-
(1990)
Biol Rev Camb Philos Soc
, vol.65
, pp. 431-471
-
-
Holliday, R.1
-
66
-
-
4444307804
-
Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines
-
DOI 10.1016/j.ygyno.2004.05.031, PII S0090825804003452
-
Huh S, Bae S, Kim Y, Lee J, Namkoong S, Lee I, Kim S, Kim C, Ahn W (2004) Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines. Gynecol Oncol 94:760-768 (Pubitemid 39194472)
-
(2004)
Gynecologic Oncology
, vol.94
, Issue.3
, pp. 760-768
-
-
Huh, S.W.1
Bae, S.M.2
Kim, Y.-W.3
Lee, J.M.4
Namkoong, S.E.5
Lee, I.P.6
Kim, S.H.7
Kim, C.K.8
Ahn, W.S.9
-
67
-
-
75449099982
-
Proteasome inhibition in human breast cancer cells with high catechol-Omethyltransferase activity by green tea polyphenol EGCG analogs
-
Huo C, Yang H, Cui QC, Dou QP, Chan TH (2010) Proteasome inhibition in human breast cancer cells with high catechol-Omethyltransferase activity by green tea polyphenol EGCG analogs. Bioorg Med Chem 18:1252-1258
-
(2010)
Bioorg Med Chem
, vol.18
, pp. 1252-1258
-
-
Huo, C.1
Yang, H.2
Cui, Q.C.3
Dou, Q.P.4
Chan, T.H.5
-
68
-
-
59249103688
-
Cancer prevention: Epigenetics steps up to the plate
-
Issa JP (2008) Cancer prevention: Epigenetics steps up to the plate. Cancer Prev Res (Phila Pa) 1:219-222
-
(2008)
Cancer Prev Res (Phila Pa)
, vol.1
, pp. 219-222
-
-
Issa, J.P.1
-
69
-
-
20444431507
-
Substrate-specific activation of sirtuins by resveratrol
-
DOI 10.1074/jbc.M500655200
-
Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman E, Caldwell S, Napper A, Curtis R, DiStefano P, Fields S, Bedalov A, Kennedy B (2005) Substrate-specific activation of sirtuins by resveratrol. J Biol Chem 280:17038-17045 (Pubitemid 41389166)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 17038-17045
-
-
Kaeberlein, M.1
McDonagh, T.2
Heltweg, B.3
Hixon, J.4
Westman, E.A.5
Caldwell, S.D.6
Napper, A.7
Curtis, R.8
DiStefano, P.S.9
Fields, S.10
Bedalov, A.11
Kennedy, B.K.12
-
70
-
-
21044439177
-
Approval summary: Azacitidine for treatment of myelodysplastic syndrome subtypes
-
DOI 10.1158/1078-0432.CCR-04-2135
-
Kaminskas E, Farrell A, Abraham S, Baird A, Hsieh L, Lee S, Leighton J, Patel H, Rahman A, Sridhara R, Wang Y, Pazdur R, FDA (2005) Approval summary: Azacitidine for treatment of myelodysplastic syndrome subtypes. Clin Cancer Res 11:3604-3608 (Pubitemid 40685574)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.10
, pp. 3604-3608
-
-
Kaminskas, E.1
Farrell, A.2
Abraham, S.3
Baird, A.4
Hsieh, L.-S.5
Lee, S.-L.6
Leighton, J.K.7
Patel, H.8
Rahman, A.9
Sridhara, R.10
Wang, Y.-C.11
Pazdur, R.12
-
71
-
-
33646687937
-
Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells
-
Kang SK, Cha SH, Jeon HG (2006) Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells. Stem Cells Dev 15:165-174
-
(2006)
Stem Cells Dev
, vol.15
, pp. 165-174
-
-
Kang, S.K.1
Cha, S.H.2
Jeon, H.G.3
-
72
-
-
77955722773
-
Computational modeling of the potential interactions of the proteasome beta5 subunit and catechol-O-methyltransferaseresistant EGCG analogs
-
Kanwar J, Mohammad I, Yang H, Huo C, Chan TH, Dou QP (2010) Computational modeling of the potential interactions of the proteasome beta5 subunit and catechol-O-methyltransferaseresistant EGCG analogs. Int J Mol Med 26:209-215
-
(2010)
Int J Mol Med
, vol.26
, pp. 209-215
-
-
Kanwar, J.1
Mohammad, I.2
Yang, H.3
Huo, C.4
Chan, T.H.5
Dou, Q.P.6
-
73
-
-
49549087270
-
Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells
-
Kato K, Long NK, Makita H, Toida M, Yamashita T, Hatakeyama D, Hara A, Mori H, Shibata T (2008) Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells. Br J Cancer 99:647-654
-
(2008)
Br J Cancer
, vol.99
, pp. 647-654
-
-
Kato, K.1
Long, N.K.2
Makita, H.3
Toida, M.4
Yamashita, T.5
Hatakeyama, D.6
Hara, A.7
Mori, H.8
Shibata, T.9
-
74
-
-
69949157311
-
Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: Implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway
-
Keum YS, Khor TO, Lin W, Shen G, Kwon KH, Barve A, Li W, Kong AN (2009) Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: Implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway. Pharm Res 26:2324-2331
-
(2009)
Pharm Res
, vol.26
, pp. 2324-2331
-
-
Keum, Y.S.1
Khor, T.O.2
Lin, W.3
Shen, G.4
Kwon, K.H.5
Barve, A.6
Li, W.7
Kong, A.N.8
-
75
-
-
46049103996
-
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
-
DOI 10.1002/ijc.23590
-
Kikuno N, Shiina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, Majid S, Igawa M, Dahiya R (2008) Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. Int J Cancer 123:552-560 (Pubitemid 351898412)
-
(2008)
International Journal of Cancer
, vol.123
, Issue.3
, pp. 552-560
-
-
Kikuno, N.1
Shiina, H.2
Urakami, S.3
Kawamoto, K.4
Hirata, H.5
Tanaka, Y.6
Majid, S.7
Igawa, M.8
Dahiya, R.9
-
78
-
-
33847076849
-
Chromatin Modifications and Their Function
-
DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
-
Kouzarides T (2007) Chromatin modifications and their function. Cell 128:693-705 (Pubitemid 46273577)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
81
-
-
17444417521
-
Cancer epigenetics
-
DOI 10.1093/hmg/ddi113
-
Laird P (2005) Cancer epigenetics. Hum Mol Genet 14(Spec No 1): R65-R76 (Pubitemid 40542622)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.SPEC. ISS. 1
-
-
Laird, P.W.1
-
82
-
-
34249299083
-
A novel prodrug of the green tea polyphenol (-)-epigallocatechin-3- gallate as a potential anticancer agent
-
DOI 10.1158/0008-5472.CAN-06-4699
-
Landis-Piwowar KR, Huo C, Chen D, Milacic V, Shi G, Chan TH, Dou QP (2007) A novel prodrug of the green tea polyphenol (-)- epigallocatechin-3- gallate as a potential anticancer agent. Cancer Res 67:4303-4310 (Pubitemid 46815078)
-
(2007)
Cancer Research
, vol.67
, Issue.9
, pp. 4303-4310
-
-
Landis-Piwowar, K.R.1
Huo, C.2
Chen, D.3
Milacic, V.4
Shi, G.5
Tak, H.C.6
Dou, Q.P.7
-
83
-
-
54849416116
-
Relationship between the methylation status of dietary flavonoids and their growthinhibitory and apoptosis-inducing activities in human cancer cells
-
Landis-Piwowar KR, Milacic V, Dou QP (2008) Relationship between the methylation status of dietary flavonoids and their growthinhibitory and apoptosis-inducing activities in human cancer cells. J Cell Biochem 105:514-523
-
(2008)
J Cell Biochem
, vol.105
, pp. 514-523
-
-
Landis-Piwowar, K.R.1
Milacic, V.2
Dou, Q.P.3
-
84
-
-
77954358651
-
Inhibition of catechol-Omicron-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG
-
Landis-Piwowar K, Chen D, Chan TH, Dou QP (2010) Inhibition of catechol-Omicron-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG. Oncol Rep 24:563-569
-
(2010)
Oncol Rep
, vol.24
, pp. 563-569
-
-
Landis-Piwowar, K.1
Chen, D.2
Chan, T.H.3
Dou, Q.P.4
-
85
-
-
0035876964
-
Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate
-
DOI 10.1002/ijc.1277
-
Lea M, Randolph V, Lee J, desBordes C (2001) Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. Int J Cancer 92:784-789 (Pubitemid 32467365)
-
(2001)
International Journal of Cancer
, vol.92
, Issue.6
, pp. 784-789
-
-
Lea, M.A.1
Randolph, V.M.2
Lee, J.E.3
DesBordes, C.4
-
86
-
-
31544441371
-
Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols
-
DOI 10.1093/carcin/bgi206
-
Lee W, Zhu B (2006) Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis 27:269-277 (Pubitemid 43159879)
-
(2006)
Carcinogenesis
, vol.27
, Issue.2
, pp. 269-277
-
-
Lee, W.J.1
Zhu, B.T.2
-
87
-
-
0141648473
-
Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis
-
Lee S, Lee H, Kim J, Lee H, Jang J, Kang G (2003) Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis. Am J Pathol 163:1371-1378 (Pubitemid 37175085)
-
(2003)
American Journal of Pathology
, vol.163
, Issue.4
, pp. 1371-1378
-
-
Lee, S.1
Lee, H.J.2
Kim, J.-H.3
Lee, H.-S.4
Jang, J.J.5
Kang, G.H.6
-
88
-
-
25144507259
-
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
-
DOI 10.1124/mol.104.008367
-
Lee W, Shim J, Zhu B (2005) Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol Pharmacol 68:1018-1030 (Pubitemid 41345793)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.4
, pp. 1018-1030
-
-
Won, J.L.1
Shim, J.-Y.2
Zhu, B.T.3
-
89
-
-
77955621544
-
Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components
-
Li Y, Tollefsbol T (2010) Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Curr Med Chem 17:2141-2151
-
(2010)
Curr Med Chem
, vol.17
, pp. 2141-2151
-
-
Li, Y.1
Tollefsbol, T.2
-
90
-
-
34250667940
-
Activation of the SIRT1 pathway and modulation of the cell cycle were involved in silymarin's protection against UV-induced A375-S2 cell apoptosis
-
DOI 10.1080/10286020600604260, PII 779554012
-
Li LH, Wu LJ, Tashiro SI, Onodera S, Uchiumi F, Ikejima T (2007) Activation of the SIRT1 pathway and modulation of the cell cycle were involved in silymarin's protection against UV-induced A375-S2 cell apoptosis. J Asian Nat Prod Res 9:245-252 (Pubitemid 46933325)
-
(2007)
Journal of Asian Natural Products Research
, vol.9
, Issue.3
, pp. 245-252
-
-
Li, L.-H.1
Wu, L.-J.2
Tashiro, S.-I.3
Onodera, S.4
Uchiumi, F.5
Ikejima, T.6
-
91
-
-
40549117477
-
Curcumin prevents and reverses murine cardiac hypertrophy
-
DOI 10.1172/JCI32865
-
Li H, Liu C, de Couto G, Ouzounian M, Sun M, Wang A, Huang Y, He C, Shi Y, Chen X, Nghiem M, Liu Y, Chen M, Dawood F, Fukuoka M, Maekawa Y, Zhang L, Leask A, Ghosh A, Kirshenbaum L, Liu P (2008) Curcumin prevents and reverses murine cardiac hypertrophy. J Clin Invest 118:879-893 (Pubitemid 351364596)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.3
, pp. 879-893
-
-
Li, H.-L.1
Liu, C.2
De Couto, G.3
Ouzounian, M.4
Sun, M.5
Wang, A.-B.6
Huang, Y.7
He, C.-W.8
Shi, Y.9
Chen, X.10
Nghiem, M.P.11
Liu, Y.12
Chen, M.13
Dawood, F.14
Fukuoka, M.15
Maekawa, Y.16
Zhang, L.17
Leask, A.18
Ghosh, A.K.19
Kirshenbaum, L.A.20
Liu, P.P.21
more..
-
92
-
-
67449084948
-
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
-
Li Y, Liu L, Andrews LG, Tollefsbol TO (2009a) Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer 125:286-296
-
(2009)
Int J Cancer
, vol.125
, pp. 286-296
-
-
Li, Y.1
Liu, L.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
93
-
-
69249096109
-
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
-
Li Y, VandenBoom Tn, Kong D, Wang Z, Ali S, Philip P, Sarkar F (2009b) Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res 69:6704-6712
-
(2009)
Cancer Res
, vol.69
, pp. 6704-6712
-
-
Li, Y.1
VandenBoom, Tn.2
Kong, D.3
Wang, Z.4
Ali, S.5
Philip, P.6
Sarkar, F.7
-
94
-
-
77952305618
-
Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression
-
Li Y, Liu L, Tollefsbol TO (2010) Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression. FASEB J 24:1442-1453
-
(2010)
FASEB J
, vol.24
, pp. 1442-1453
-
-
Li, Y.1
Liu, L.2
Tollefsbol, T.O.3
-
95
-
-
77953188130
-
Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer
-
Liang G, Tang A, Lin X, Li L, Zhang S, Huang Z, Tang H, Li QQ (2010) Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer. Int J Oncol 37:111-123
-
(2010)
Int J Oncol
, vol.37
, pp. 111-123
-
-
Liang, G.1
Tang, A.2
Lin, X.3
Li, L.4
Zhang, S.5
Huang, Z.6
Tang, H.7
Li, Q.Q.8
-
97
-
-
18744403080
-
Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation
-
DOI 10.1111/j.1745-7254.2005.00081.x
-
Liu H, Chen Y, Cui G, Zhou J (2005) Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating BNHL cell line Raji proliferation. Acta Pharmacol Sin 26:603-609 (Pubitemid 40676173)
-
(2005)
Acta Pharmacologica Sinica
, vol.26
, Issue.5
, pp. 603-609
-
-
Liu, H.-L.1
Chen, Y.2
Cui, G.-H.3
Zhou, J.-F.4
-
98
-
-
77957590701
-
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factorkappaB pathway and subsequently downregulating expression of matrix metalloproteinases
-
Liu PL, Tsai JR, Charles AL, Hwang JJ, Chou SH, Ping YH, Lin FY, Chen YL, Hung CY, Chen WC, Chen YH, Chong IW (2010) Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factorkappaB pathway and subsequently downregulating expression of matrix metalloproteinases. Mol Nutr Food Res 54:S196-S204
-
(2010)
Mol Nutr Food Res
, vol.54
-
-
Liu, P.L.1
Tsai, J.R.2
Charles, A.L.3
Hwang, J.J.4
Chou, S.H.5
Ping, Y.H.6
Lin, F.Y.7
Chen, Y.L.8
Hung, C.Y.9
Chen, W.C.10
Chen, Y.H.11
Chong, I.W.12
-
99
-
-
42349103444
-
Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification
-
DOI 10.1158/0008-5472.CAN-07-2290
-
Majid S, Kikuno N, Nelles J, Noonan E, Tanaka Y, Kawamoto K, Hirata H, Li L, Zhao H, Okino S, Place R, Pookot D, Dahiya R (2008) Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification. Cancer Res 68:2736-2744 (Pubitemid 351556271)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 2736-2744
-
-
Majid, S.1
Kikuno, N.2
Nelles, J.3
Noonan, E.4
Tanaka, Y.5
Kawamoto, K.6
Hirata, H.7
Li, L.C.8
Zhao, H.9
Okino, S.T.10
Place, R.F.11
Pookot, D.12
Dahiya, R.13
-
100
-
-
64349112758
-
BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer
-
Majid S, Dar AA, Ahmad AE, Hirata H, Kawakami K, Shahryari V, Saini S, Tanaka Y, Dahiya AV, Khatri G, Dahiya R (2009) BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. Carcinogenesis 30:662-670
-
(2009)
Carcinogenesis
, vol.30
, pp. 662-670
-
-
Majid, S.1
Dar, A.A.2
Ahmad, A.E.3
Hirata, H.4
Kawakami, K.5
Shahryari, V.6
Saini, S.7
Tanaka, Y.8
Dahiya, A.V.9
Khatri, G.10
Dahiya, R.11
-
101
-
-
77954653079
-
Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines
-
(in press)
-
Mao QQ, Bai Y, Lin YW, Zheng XY, Qin J, Yang K, Xie LP (2010) Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines.Mol Nutr Food Res (in press)
-
(2010)
Mol Nutr Food Res
-
-
Mao, Q.Q.1
Bai, Y.2
Lin, Y.W.3
Zheng, X.Y.4
Qin, J.5
Yang, K.6
Xie, L.P.7
-
102
-
-
33746127271
-
Curcumin is an inhibitor of p300 histone acetylatransferase
-
DOI 10.2174/157340606776056133
-
Marcu MG, Jung YJ, Lee S, Chung EJ, Lee MJ, Trepel J, Neckers L (2006) Curcumin is an inhibitor of p300 histone acetylatransferase. Med Chem 2:169-174 (Pubitemid 44083157)
-
(2006)
Medicinal Chemistry
, vol.2
, Issue.2
, pp. 169-174
-
-
Marcu, M.G.1
Jung, Y.-J.2
Lee, S.3
Chung, E.-J.4
Lee, M.-J.5
Trepel, J.6
Neckers, L.7
-
103
-
-
49249116407
-
A work in progress: The clinical development of histone deacetylase inhibitors
-
Marsoni S, Damia G, Camboni G (2008) A work in progress: The clinical development of histone deacetylase inhibitors. Epigenetics 3:164-171
-
(2008)
Epigenetics
, vol.3
, pp. 164-171
-
-
Marsoni, S.1
Damia, G.2
Camboni, G.3
-
104
-
-
38449107684
-
Cell cycle control as a basis for cancer chemoprevention through dietary agents
-
DOI 10.2741/2834
-
Meeran S, Katiyar S (2008) Cell cycle control as a basis for cancer chemoprevention through dietary agents. Front Biosci 13:2191-2202 (Pubitemid 351589245)
-
(2008)
Frontiers in Bioscience
, vol.13
, Issue.6
, pp. 2191-2202
-
-
Meeran, S.M.1
Katiyar, S.K.2
-
105
-
-
77955352742
-
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
-
Meeran S, Patel S, Tollefsbol T (2010) Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS ONE 5:e11457
-
(2010)
PLoS ONE
, vol.5
-
-
Meeran, S.1
Patel, S.2
Tollefsbol, T.3
-
106
-
-
51249121642
-
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2
-
Meja K, Rajendrasozhan S, Adenuga D, Biswas S, Sundar I, Spooner G, Marwick J, Chakravarty P, Fletcher D, Whittaker P, Megson I, Kirkham P, Rahman I (2008) Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. Am J Respir Cell Mol Biol 39:312-323
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 312-323
-
-
Meja, K.1
Rajendrasozhan, S.2
Adenuga, D.3
Biswas, S.4
Sundar, I.5
Spooner, G.6
Marwick, J.7
Chakravarty, P.8
Fletcher, D.9
Whittaker, P.10
Megson, I.11
Kirkham, P.12
Rahman, I.13
-
107
-
-
0345791481
-
Exceptionally High Protection of Photocarcinogenesis by Topical Application of (-)-Epigallocatechin-3-Gallate in Hydrophilic Cream in SKH-1 Hairless Mouse Model: Relationship to Inhibition of UVB-Induced Global DNA Hypomethylation
-
Mittal A, Piyathilake C, Hara Y, Katiyar S (2003) Exceptionally high protection of photocarcinogenesis by topical application of (-)- epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: Relationship to inhibition of UVB-induced global DNA hypomethylation. Neoplasia 5:555-565 (Pubitemid 38045092)
-
(2003)
Neoplasia
, vol.5
, Issue.6
, pp. 555-565
-
-
Mittal, A.1
Piyathilake, C.2
Hara, Y.3
Katiyar, S.K.4
-
108
-
-
36749087040
-
Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells
-
DOI 10.1158/1535-7163.MCT-07-0117
-
Moiseeva EP, Almeida GM, Jones GD, Manson MM (2007) Extended treatmentwith physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. Mol Cancer Ther 6:3071-3079 (Pubitemid 350206785)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.11
, pp. 3071-3079
-
-
Moiseeva, E.P.1
Almeida, G.M.2
Jones, G.D.D.3
Manson, M.M.4
-
109
-
-
41149141516
-
Histone deacetylases: Target enzymes for cancer therapy
-
Mottet D, Castronovo V (2008) Histone deacetylases: Target enzymes for cancer therapy. Clin Exp Metastasis 25:183-189
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 183-189
-
-
Mottet, D.1
Castronovo, V.2
-
110
-
-
76549087131
-
Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate
-
Morey Kinney SR, Zhang W, Pascual M, Greally JM, Gillard BM, Karasik E, Foster BA, Karpf AR (2009) Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate. Cancer Prev Res (Phila Pa) 2:1065-1075
-
(2009)
Cancer Prev Res (Phila Pa)
, vol.2
, pp. 1065-1075
-
-
Morey Kinney, S.R.1
Zhang, W.2
Pascual, M.3
Greally, J.M.4
Gillard, B.M.5
Karasik, E.6
Foster, B.A.7
Karpf, A.R.8
-
111
-
-
40549135974
-
The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats
-
DOI 10.1172/JCI33160
-
Morimoto T, Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T, Hasegawa K (2008) The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats. J Clin Invest 118:868-878 (Pubitemid 351364595)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.3
, pp. 868-878
-
-
Morimoto, T.1
Sunagawa, Y.2
Kawamura, T.3
Takaya, T.4
Wada, H.5
Nagasawa, A.6
Komeda, M.7
Fujita, M.8
Shimatsu, A.9
Kita, T.10
Hasegawa, K.11
-
112
-
-
0034080382
-
Tea polyphenols: Prevention of cancer and optimizing health
-
discussion 1703S-1694S
-
Mukhtar H, Ahmad N (2000) Tea polyphenols: Prevention of cancer and optimizing health. Am J Clin Nutr 71:1698S-1702S, discussion 1703S-1694S
-
(2000)
Am J Clin Nutr
, vol.71
-
-
Mukhtar, H.1
Ahmad, N.2
-
113
-
-
67650886038
-
Black tea polyphenols targetmatrixmetalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model
-
Murugan RS, Vinothini G, Hara Y, Nagini S (2009) Black tea polyphenols targetmatrixmetalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model. Anticancer Res 29:2301-2305
-
(2009)
Anticancer Res
, vol.29
, pp. 2301-2305
-
-
Murugan, R.S.1
Vinothini, G.2
Hara, Y.3
Nagini, S.4
-
114
-
-
4143130097
-
A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase
-
DOI 10.1158/0008-5472.CAN-04-1326
-
Myzak MC, Karplus PA, Chung FL, Dashwood RH (2004) A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase. Cancer Res 64:5767-5774 (Pubitemid 39095576)
-
(2004)
Cancer Research
, vol.64
, Issue.16
, pp. 5767-5774
-
-
Myzak, M.C.1
Karplus, P.A.2
Chung, F.-L.3
Dashwood, R.H.4
-
115
-
-
33645825587
-
min mice
-
DOI 10.1096/fj.05-4785fje
-
Myzak MC, Dashwood WM, Orner GA, Ho E, Dashwood RH (2006a) Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. FASEB J 20:506-508 (Pubitemid 46671231)
-
(2006)
FASEB Journal
, vol.20
, Issue.3
, pp. 506-508
-
-
Myzak, M.C.1
Dashwood, W.M.2
Orner, G.A.3
Ho, E.4
Dashwood, R.H.5
-
116
-
-
33645324413
-
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
-
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E (2006b) Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. Carcinogenesis 27:811-819
-
(2006)
Carcinogenesis
, vol.27
, pp. 811-819
-
-
Myzak, M.C.1
Hardin, K.2
Wang, R.3
Dashwood, R.H.4
Ho, E.5
-
117
-
-
33744990610
-
Dietary agents as histone deacetylase inhibitors
-
DOI 10.1002/mc.20224
-
Myzak M, Ho E, Dashwood R (2006c) Dietary agents as histone deacetylase inhibitors. Mol Carcinog 45:443-446 (Pubitemid 43865853)
-
(2006)
Molecular Carcinogenesis
, vol.45
, Issue.6
, pp. 443-446
-
-
Myzak, M.C.1
Ho, E.2
Dashwood, R.H.3
-
118
-
-
33846838750
-
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
-
Myzak MC, Tong P, Dashwood WM, Dashwood RH, Ho E (2007) Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Exp Biol Med (Maywood) 232:227-234 (Pubitemid 46203291)
-
(2007)
Experimental Biology and Medicine
, vol.232
, Issue.2
, pp. 227-234
-
-
Myzak, M.C.1
Tong, P.2
Dashwood, W.-M.3
Dashwood, R.H.4
Ho, E.5
-
119
-
-
39149092699
-
Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells
-
DOI 10.1007/s11095-007-9364-7
-
Nair S, Hebbar V, Shen G, Gopalakrishnan A, Khor TO, Yu S, Xu C, Kong AN (2008) Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. Pharm Res 25:387-399 (Pubitemid 351257971)
-
(2008)
Pharmaceutical Research
, vol.25
, Issue.2
, pp. 387-399
-
-
Nair, S.1
Hebbar, V.2
Shen, G.3
Gopalakrishnan, A.4
Khor, T.O.5
Yu, S.6
Xu, C.7
Kong, A.-N.8
-
120
-
-
63049105405
-
Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds
-
Nian H, Delage B, Ho E, Dashwood R (2009) Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds. Environ Mol Mutagen 50:213-221
-
(2009)
Environ Mol Mutagen
, vol.50
, pp. 213-221
-
-
Nian, H.1
Delage, B.2
Ho, E.3
Dashwood, R.4
-
121
-
-
77953232497
-
Anti-melanoma effects of vorinostat in combination with polyphenolic antioxidant (-) - epigallocatechin-3-gallate (EGCG)
-
Nihal M, Roelke CT, Wood GS (2010) Anti-melanoma effects of vorinostat in combination with polyphenolic antioxidant (-)- epigallocatechin-3-gallate (EGCG). Pharm Res 27:1103-1114
-
(2010)
Pharm Res
, vol.27
, pp. 1103-1114
-
-
Nihal, M.1
Roelke, C.T.2
Wood, G.S.3
-
122
-
-
73749085369
-
The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells
-
Paluszczak J, Krajka-Kuzniak V, Baer-Dubowska W (2010) The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells. Toxicol Lett 192:119-125
-
(2010)
Toxicol Lett
, vol.192
, pp. 119-125
-
-
Paluszczak, J.1
Krajka-Kuzniak, V.2
Baer-Dubowska, W.3
-
123
-
-
77951225012
-
Promoter demethylation and chromatin remodeling by green tea polyphenols leads to reexpression of GSTP1 in human prostate cancer cells
-
Pandey M, Shukla S, Gupta S (2010) Promoter demethylation and chromatin remodeling by green tea polyphenols leads to reexpression of GSTP1 in human prostate cancer cells. Int J Cancer 126:2520-2533
-
(2010)
Int J Cancer
, vol.126
, pp. 2520-2533
-
-
Pandey, M.1
Shukla, S.2
Gupta, S.3
-
124
-
-
77956591357
-
Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells
-
Papoutsis AJ, Lamore SD, Wondrak GT, Selmin OI, Romagnolo DF (2010) Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells. J Nutr 140(9):1607-1614
-
(2010)
J Nutr
, vol.140
, Issue.9
, pp. 1607-1614
-
-
Papoutsis, A.J.1
Lamore, S.D.2
Wondrak, G.T.3
Selmin, O.I.4
Romagnolo, D.F.5
-
125
-
-
70949103350
-
Modulation of microRNA associated with ovarian cancer cells by genistein
-
Parker L, Taylor D, Kesterson J, Metzinger D, Gercel-Taylor C (2009) Modulation of microRNA associated with ovarian cancer cells by genistein. Eur J Gynaecol Oncol 30:616-621
-
(2009)
Eur J Gynaecol Oncol
, vol.30
, pp. 616-621
-
-
Parker, L.1
Taylor, D.2
Kesterson, J.3
Metzinger, D.4
Gercel-Taylor, C.5
-
126
-
-
34147135143
-
Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines
-
DOI 10.1158/1535-7163.MCT-06-0494
-
Pledgie-Tracy A, Sobolewski MD, Davidson NE (2007) Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Mol Cancer Ther 6:1013-1021 (Pubitemid 46554571)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.3
, pp. 1013-1021
-
-
Pledgie-Tracy, A.1
Sobolewski, M.D.2
Davidson, N.E.3
-
127
-
-
65649152375
-
Phase I study of MG98, an oligonucleotide antisense inhibitor of human DNA methyltransferase 1, given as a 7-day infusion in patients with advanced solid tumors
-
Plummer R, Vidal L, Griffin M, Lesley M, de Bono J, Coulthard S, Sludden J, Siu L, Chen E, Oza A, Reid G, McLeod A, Besterman J, Lee C, Judson I, Calvert H, Boddy A (2009) Phase I study of MG98, an oligonucleotide antisense inhibitor of human DNA methyltransferase 1, given as a 7-day infusion in patients with advanced solid tumors. Clin Cancer Res 15:3177-3183
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3177-3183
-
-
Plummer, R.1
Vidal, L.2
Griffin, M.3
Lesley, M.4
De Bono, J.5
Coulthard, S.6
Sludden, J.7
Siu, L.8
Chen, E.9
Oza, A.10
Reid, G.11
McLeod, A.12
Besterman, J.13
Lee, C.14
Judson, I.15
Calvert, H.16
Boddy, A.17
-
128
-
-
65349090672
-
Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation
-
Pollack BP, Sapkota B, Boss JM (2009) Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. Photochem Photobiol 85:652-662
-
(2009)
Photochem Photobiol
, vol.85
, pp. 652-662
-
-
Pollack, B.P.1
Sapkota, B.2
Boss, J.M.3
-
129
-
-
61649113446
-
Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
-
Qin W, Zhu W, Shi H, Hewett JE, Ruhlen RL, MacDonald RS, Rottinghaus GE, Chen YC, Sauter ER (2009) Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr Cancer 61:238-244
-
(2009)
Nutr Cancer
, vol.61
, pp. 238-244
-
-
Qin, W.1
Zhu, W.2
Shi, H.3
Hewett, J.E.4
Ruhlen, R.L.5
MacDonald, R.S.6
Rottinghaus, G.E.7
Chen, Y.C.8
Sauter, E.R.9
-
130
-
-
27744529808
-
Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis
-
DOI 10.1093/carcin/bgi153
-
Quante M, Heeg S, von Werder A, Goessel G, Fulda C, Doebele M, Nakagawa H, Beijersbergen R, BlumH, Opitz O (2005) Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis. Carcinogenesis 26:1879-1889 (Pubitemid 41631260)
-
(2005)
Carcinogenesis
, vol.26
, Issue.11
, pp. 1879-1889
-
-
Quante, M.1
Heeg, S.2
Von Werder, A.3
Goessel, G.4
Fulda, C.5
Doebele, M.6
Nakagawa, H.7
Beijersbergen, R.8
Blum, H.E.9
Opitz, O.G.10
-
131
-
-
57749176653
-
Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia
-
Raynal NJ, Charbonneau M, Momparler LF, Momparler RL (2008) Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia. Oncol Res 17:223-230
-
(2008)
Oncol Res
, vol.17
, pp. 223-230
-
-
Raynal, N.J.1
Charbonneau, M.2
Momparler, L.F.3
Momparler, R.L.4
-
132
-
-
55949095821
-
Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
-
Reuter S, Eifes S, Dicato M, Aggarwal BB, Diederich M (2008) Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells. Biochem Pharmacol 76:1340-1351
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 1340-1351
-
-
Reuter, S.1
Eifes, S.2
Dicato, M.3
Aggarwal, B.B.4
Diederich, M.5
-
133
-
-
77952180832
-
Green tea polyphenol suppresses tumor invasion and angiogenesis in Nbutyl-(- 4-hydroxybutyl) nitrosamine-induced bladder cancer
-
Sagara Y, Miyata Y, Nomata K, Hayashi T, Kanetake H (2010) Green tea polyphenol suppresses tumor invasion and angiogenesis in Nbutyl-(- 4-hydroxybutyl) nitrosamine-induced bladder cancer. Cancer Epidemiol 34:350-354
-
(2010)
Cancer Epidemiol
, vol.34
, pp. 350-354
-
-
Sagara, Y.1
Miyata, Y.2
Nomata, K.3
Hayashi, T.4
Kanetake, H.5
-
134
-
-
33749598345
-
Epigenetic activation of tumor suppressor microRNAs in human cancer cells
-
Saito Y, Jones P (2006) Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Cell Cycle 5:2220-2222 (Pubitemid 44546557)
-
(2006)
Cell Cycle
, vol.5
, Issue.19
, pp. 2220-2222
-
-
Saito, Y.1
Jones, P.A.2
-
135
-
-
4143059348
-
Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma
-
DOI 10.1016/j.urology.2004.03.045, PII S0090429504004170
-
Sasamura H, Takahashi A, Yuan J, Kitamura H, Masumori N, Miyao N, Itoh N, Tsukamoto T (2004) Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma. Urology 64:389-393 (Pubitemid 39092489)
-
(2004)
Urology
, vol.64
, Issue.2
, pp. 389-393
-
-
Sasamura, H.1
Takahashi, A.2
Yuan, J.3
Kitamura, H.4
Masumori, N.5
Miyao, N.6
Itoh, N.7
Tsukamoto, T.8
-
136
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
DOI 10.1038/nature03672
-
Seligson D, Horvath S, Shi T, Yu H, Tze S, Grunstein M, Kurdistani S (2005) Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435:1262-1266 (Pubitemid 40943093)
-
(2005)
Nature
, vol.435
, Issue.7046
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
137
-
-
68949110352
-
Phase I trial of daily oral polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia
-
Shanafelt T, Call T, Zent C, LaPlant B, Bowen D, Roos M, Secreto C, Ghosh A, Kabat B, Lee M, Yang C, Jelinek D, Erlichman C, Kay N (2009) Phase I trial of daily oral polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia. J Clin Oncol 27:3808-3814
-
(2009)
J Clin Oncol
, vol.27
, pp. 3808-3814
-
-
Shanafelt, T.1
Call, T.2
Zent, C.3
LaPlant, B.4
Bowen, D.5
Roos, M.6
Secreto, C.7
Ghosh, A.8
Kabat, B.9
Lee, M.10
Yang, C.11
Jelinek, D.12
Erlichman, C.13
Kay, N.14
-
139
-
-
34447523548
-
Role of Curcumin in Cancer Therapy
-
DOI 10.1016/j.currproblcancer.2007.04.001, PII S0147027207000219, Role of Curcumin in Cancer Therapy
-
Shishodia S, Chaturvedi M, Aggarwal B (2007) Role of curcumin in cancer therapy. Curr Probl Cancer 31:243-305 (Pubitemid 47077491)
-
(2007)
Current Problems in Cancer
, vol.31
, Issue.4
, pp. 243-305
-
-
Shishodia, S.1
Chaturvedi, M.M.2
Aggarwal, B.B.3
-
140
-
-
32944478433
-
Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis
-
DOI 10.1158/0008-5472.CAN-05-1332
-
Singh AV, Franke AA, Blackburn GL, Zhou JR (2006) Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis. Cancer Res 66:1851-1858 (Pubitemid 43259972)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1851-1858
-
-
Singh, A.V.1
Franke, A.A.2
Blackburn, G.L.3
Zhou, J.-R.4
-
141
-
-
77953539793
-
Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells
-
Stefanska B, Rudnicka K, Bednarek A, Fabianowska-Majewska K (2010) Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells. Eur J Pharmacol 638:47-53
-
(2010)
Eur J Pharmacol
, vol.638
, pp. 47-53
-
-
Stefanska, B.1
Rudnicka, K.2
Bednarek, A.3
Fabianowska-Majewska, K.4
-
142
-
-
13844280432
-
The novel targets for antiangiogenesis of genistein on human cancer cells
-
Su SJ, Yeh TM, Chuang WJ, Ho CL, Chang KL, Cheng HL, Liu HS, Hsu PY, Chow NH (2005) The novel targets for antiangiogenesis of genistein on human cancer cells. Biochem Pharmacol 69:307-318
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 307-318
-
-
Su, S.J.1
Yeh, T.M.2
Chuang, W.J.3
Ho, C.L.4
Chang, K.L.5
Cheng, H.L.6
Liu, H.S.7
Hsu, P.Y.8
Chow, N.H.9
-
143
-
-
70349316774
-
Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression
-
Sun Q, Cong R, Yan H, Gu H, Zeng Y, Liu N, Chen J, Wang B (2009) Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression. Oncol Rep 22:563-567
-
(2009)
Oncol Rep
, vol.22
, pp. 563-567
-
-
Sun, Q.1
Cong, R.2
Yan, H.3
Gu, H.4
Zeng, Y.5
Liu, N.6
Chen, J.7
Wang, B.8
-
144
-
-
69349093211
-
Environmental influences on epigenetic profiles
-
Suter M, Aagaard-Tillery K (2009) Environmental influences on epigenetic profiles. Semin Reprod Med 27:380-390
-
(2009)
Semin Reprod Med
, vol.27
, pp. 380-390
-
-
Suter, M.1
Aagaard-Tillery, K.2
-
145
-
-
57349126317
-
Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein
-
Tang W, Newbold R, Mardilovich K, Jefferson W, Cheng R, Medvedovic M, Ho S (2008) Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein. Endocrinology 149:5922-5931
-
(2008)
Endocrinology
, vol.149
, pp. 5922-5931
-
-
Tang, W.1
Newbold, R.2
Mardilovich, K.3
Jefferson, W.4
Cheng, R.5
Medvedovic, M.6
Ho, S.7
-
146
-
-
0027535235
-
Effects of DNA methylation on DNA-binding proteins and gene expression
-
DOI 10.1016/0959-437X(93)90027-M
-
Tate P, Bird A (1993) Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev 3:226-231 (Pubitemid 23108662)
-
(1993)
Current Opinion in Genetics and Development
, vol.3
, Issue.2
, pp. 226-231
-
-
Tate, P.H.1
Bird, A.P.2
-
147
-
-
63349102182
-
Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells
-
Telang U, Brazeau D, Morris M (2009) Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells. Exp Biol Med (Maywood) 234:287-295
-
(2009)
Exp Biol Med (Maywood)
, vol.234
, pp. 287-295
-
-
Telang, U.1
Brazeau, D.2
Morris, M.3
-
148
-
-
40949119020
-
Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy
-
DOI 10.1038/sj.bjp.0707666, PII 0707666
-
Tikoo K, Meena R, Kabra D, Gaikwad A (2008) Change in posttranslational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocininduced type I diabetic nephropathy. Br J Pharmacol 153:1225-1231 (Pubitemid 351415498)
-
(2008)
British Journal of Pharmacology
, vol.153
, Issue.6
, pp. 1225-1231
-
-
Tikoo, K.1
Meena, R.L.2
Kabra, D.G.3
Gaikwad, A.B.4
-
149
-
-
23244450241
-
Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane
-
Traka M, Gasper A, Smith J, Hawkey C, Bao Y, Mithen R (2005) Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. J Nutr 135:1865-1872 (Pubitemid 41099743)
-
(2005)
Journal of Nutrition
, vol.135
, Issue.8
, pp. 1865-1872
-
-
Traka, M.1
Gasper, A.V.2
Smith, J.A.3
Hawkey, C.J.4
Bao, Y.5
Mithen, R.F.6
-
150
-
-
77954887577
-
Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo
-
Tran PL, Kim SA, Choi HS, Yoon JH, Ahn SG (2010) Epigallocatechin-3- gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo. BMC Cancer 10:276
-
(2010)
BMC Cancer
, vol.10
, pp. 276
-
-
Tran, P.L.1
Kim, S.A.2
Choi, H.S.3
Yoon, J.H.4
Ahn, S.G.5
-
151
-
-
74049144587
-
Phase II randomized, placebocontrolled trial of green tea extract in patients with high-risk oral premalignant lesions
-
Tsao A, Liu D, Martin J, Tang X, Lee J, El-Naggar A, Wistuba I, Culotta K, Mao L, Gillenwater A, Sagesaka Y, Hong W, Papadimitrakopoulou V (2009) Phase II randomized, placebocontrolled trial of green tea extract in patients with
-
(2009)
Cancer Prev Res (Phila Pa)
, vol.2
, pp. 931-941
-
-
Tsao, A.1
Liu, D.2
Martin, J.3
Tang, X.4
Lee, J.5
El-Naggar, A.6
Wistuba, I.7
Culotta, K.8
Mao, L.9
Gillenwater, A.10
Sagesaka, Y.11
Hong, W.12
Papadimitrakopoulou, V.13
-
152
-
-
77952611330
-
Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/ Wnt and activation of p53 signaling pathways
-
Vanamala J, Reddivari L, Radhakrishnan S, Tarver C (2010) Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/ Wnt and activation of p53 signaling pathways. BMC Cancer 10:238
-
(2010)
BMC Cancer
, vol.10
, pp. 238
-
-
Vanamala, J.1
Reddivari, L.2
Radhakrishnan, S.3
Tarver, C.4
-
153
-
-
70349975929
-
Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer
-
Volate SR, Muga SJ, Issa AY, Nitcheva D, Smith T, Wargovich MJ (2009) Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. Mol Carcinog 48:920-933
-
(2009)
Mol Carcinog
, vol.48
, pp. 920-933
-
-
Volate, S.R.1
Muga, S.J.2
Issa, A.Y.3
Nitcheva, D.4
Smith, T.5
Wargovich, M.J.6
-
154
-
-
0035542974
-
Methyl CpG-binding proteins and transcriptional repression
-
Wade P (2001) Methyl CpG-binding proteins and transcriptional repression. Bioessays 23:1131-1137
-
(2001)
Bioessays
, vol.23
, pp. 1131-1137
-
-
Wade, P.1
-
155
-
-
53149144656
-
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis
-
Wang R, Zheng Y, Kim H, Xu X, Cao L, Luhasen T, Lee M, Xiao C, Vassilopoulos A, Chen W, Gardner K, Man Y, Hung M, Finkel T, Deng C (2008) Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis. Mol Cell 32:11-20
-
(2008)
Mol Cell
, vol.32
, pp. 11-20
-
-
Wang, R.1
Zheng, Y.2
Kim, H.3
Xu, X.4
Cao, L.5
Luhasen, T.6
Lee, M.7
Xiao, C.8
Vassilopoulos, A.9
Chen, W.10
Gardner, K.11
Man, Y.12
Hung, M.13
Finkel, T.14
Deng, C.15
-
157
-
-
13444305417
-
Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients
-
DOI 10.1093/carcin/bgh304
-
Yuasa Y, Nagasaki H, Akiyama Y, Sakai H, Nakajima T, Ohkura Y, Takizawa T, Koike M, Tani M, Iwai T, Sugihara K, Imai K, Nakachi K (2005) Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients. Carcinogenesis 26:193-200 (Pubitemid 40207715)
-
(2005)
Carcinogenesis
, vol.26
, Issue.1
, pp. 193-200
-
-
Yuasa, Y.1
Nagasaki, H.2
Akiyama, Y.3
Sakai, H.4
Nakajima, T.5
Ohkura, Y.6
Takizawa, T.7
Koike, M.8
Tani, M.9
Iwai, T.10
Sugihara, K.11
Imai, K.12
Nakachi, K.13
-
158
-
-
64249158774
-
DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients
-
Yuasa Y, Nagasaki H, Akiyama Y, Hashimoto Y, Takizawa T, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K (2009) DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients. Int J Cancer 124:2677-2682
-
(2009)
Int J Cancer
, vol.124
, pp. 2677-2682
-
-
Yuasa, Y.1
Nagasaki, H.2
Akiyama, Y.3
Hashimoto, Y.4
Takizawa, T.5
Kojima, K.6
Kawano, T.7
Sugihara, K.8
Imai, K.9
Nakachi, K.10
-
159
-
-
77954595294
-
Effects of epigallocatechin gallate on regulatory T cell number and function in obese v. lean volunteers
-
Yun JM, Jialal I, Devaraj S (2010a) Effects of epigallocatechin gallate on regulatory T cell number and function in obese v. lean volunteers. Br J Nutr 103:1771-1777
-
(2010)
Br J Nutr
, vol.103
, pp. 1771-1777
-
-
Yun, J.M.1
Jialal, I.2
Devaraj, S.3
-
160
-
-
79952363576
-
Epigenetic regulation of high glucose-induced proinflammatory cytokine production inmonocytes by curcumin
-
(in press)
-
Yun JM, Jialal I, Devaraj S (2010b) Epigenetic regulation of high glucose-induced proinflammatory cytokine production inmonocytes by curcumin. J Nutr Biochem (in press)
-
(2010)
J Nutr Biochem
-
-
Yun, J.M.1
Jialal, I.2
Devaraj, S.3
-
161
-
-
77649190601
-
Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice
-
Zhang D, Al-Hendy M, Richard-Davis G, Montgomery-Rice V, Sharan C, Rajaratnam V, Khurana A, Al-Hendy A (2010) Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice. Am J Obstet Gynecol 202(289):e281-e289
-
(2010)
Am J Obstet Gynecol
, vol.202
, Issue.289
-
-
Zhang, D.1
Al-Hendy, M.2
Richard-Davis, G.3
Montgomery-Rice, V.4
Sharan, C.5
Rajaratnam, V.6
Khurana, A.7
Al-Hendy, A.8
|